Current Medical Research and Opinion, Volume 34, Issue 5 (2018)

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Current Medical Research and Opinion, Volume 34, Issue 5 (2018)

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Oncology

Oncology

Review
ASXL1 mutations in myeloid neoplasms: pathogenetic considerations, impact on clinical outcomes and survival
Juliana Alvarez Argote & Constantin A. Dasanu
Pages: 757-763
Published online: 24 Jan 2017
AbstractforASXL1 mutations in myeloid neoplasms: pathogenetic considerations, impact on clinical outcomes and survival | Full Text | References | PDF (798.4 KB)
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Pharmacoeconomics

Article
Systematic bias in predictions of new drugs’ budget impact: analysis of a sample of recent US drug launches
Michael S. Broder, Jenelle M. Zambrano, Jackie Lee & Richard S. Marken
Pages: 765-773
Published online: 03 May 2017
AbstractforSystematic bias in predictions of new drugs’ budget impact: analysis of a sample of recent US drug launches | Full Text | References | PDF (864 KB)
  • 411 Views
  • 8 CrossRef citations
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Oncology

Article
Adjusted comparison of daratumumab monotherapy versus real-world historical control data from the Czech Republic in heavily pretreated and highly refractory multiple myeloma patients
Tomáš Jelínek, Vladimír Maisnar, Luděk Pour, Ivan Špička, Jiří Minařík, Evžen Gregora, Petr Kessler, Michal Sýkora, Hana Fraňková, Dagmar Adamová, Marek Wróbel, Peter Mikula, Jiří Jarkovský, Joris Diels, Xenia Gatopoulou, Šárka Veselá, Hervé Besson, Lucie Brožová, Tetsuro Ito & Roman Hájek
Pages: 775-783
Published online: 15 Feb 2018
AbstractforAdjusted comparison of daratumumab monotherapy versus real-world historical control data from the Czech Republic in heavily pretreated and highly refractory multiple myeloma patients | Full Text | References | PDF (1.2 MB)
  • 784 Views
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Urology

Article
Mirabegron improves quality-of-life, treatment satisfaction, and persistence in patients with overactive bladder: a multi-center, non-interventional, real-world, 12-month study
Robert Freeman, Steve Foley, José Rosa Arias, Eduardo Vicente, Robert Grill, Zuzana Kachlirova, Anny Stari, Moses Huang & Nurul Choudhury
Pages: 785-793
Published online: 10 Jan 2018
AbstractforMirabegron improves quality-of-life, treatment satisfaction, and persistence in patients with overactive bladder: a multi-center, non-interventional, real-world, 12-month study | Full Text | References | PDF (1.1 MB) | Supplemental
  • 442 Views
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Oncology

Article
Tyrosine kinase inhibitors for advanced or metastatic thyroid cancer: a meta-analysis of randomized controlled trials
Jen-Wei Liu, Chiehfeng Chen, El-Wui Loh, Chun-Cheng Chu, Mu-Yi Wang, Hsin-Ju Ouyang, Ya-Ting Chang, Wei-Zhan Zhuang, Ching-Wen Chou, Der-Jr Huang, Chia-Hwa Lee, Yun Yen & Ka-Wai Tam
Pages: 795-803
Published online: 12 Sep 2017
AbstractforTyrosine kinase inhibitors for advanced or metastatic thyroid cancer: a meta-analysis of randomized controlled trials | Full Text | References | PDF (2.1 MB)
  • 420 Views
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Article
Risk of osteoporosis in thyroid cancer patients using levothyroxine: a population-based study
Shih-Yi Lin, Cheng-Li Lin, Hsien-Te Chen & Chia-Hung Kao
Pages: 805-812
Published online: 05 Oct 2017
AbstractforRisk of osteoporosis in thyroid cancer patients using levothyroxine: a population-based study | Full Text | References | PDF (676.1 KB)
  • 385 Views
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Article
Overall survival in patients with glioblastoma before and after bevacizumab approval
Derek R. Johnson, Antonio M. P. Omuro, Arliene Ravelo, Nicolas Sommer, Annie Guerin, Raluca Ionescu-Ittu, Sherry Shi, Alex Macalalad & Joon H. Uhm
Pages: 813-820
Published online: 10 Nov 2017
AbstractforOverall survival in patients with glioblastoma before and after bevacizumab approval | Full Text | References | PDF (1.2 MB) | Supplemental
  • 441 Views
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General Medicine

Editorial
Healthcare reform in China: challenges and opportunities
Marianthi Papagianni & Konstantinos Tziomalos
Pages: 821-823
Published online: 01 Dec 2017
First Page PreviewforHealthcare reform in China: challenges and opportunities | Full Text | References | PDF (264.9 KB)
  • 3797 Views
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Free Access

Oncology

Review
First-line vascular endothelial growth factor targeted therapy in renal cell carcinoma: priming the tumor microenvironment for immunotherapy
Nizar Tannir, Hans Hammers & Asim Amin
Pages: 825-831
Published online: 01 Feb 2018
AbstractforFirst-line vascular endothelial growth factor targeted therapy in renal cell carcinoma: priming the tumor microenvironment for immunotherapy | Full Text | References | PDF (1.2 MB)
  • 491 Views
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Ageing

Article
Impact of medication reviews on inappropriate prescribing in aged care
Linda Ghali Koria, Tabish Syed Zaidi, Gregory Peterson, Prasad Nishtala, Paul J. Hannah & Ronald Castelino
Pages: 833-838
Published online: 05 Feb 2018
AbstractforImpact of medication reviews on inappropriate prescribing in aged care | Full Text | References | PDF (627.8 KB)
  • 876 Views
  • 13 CrossRef citations
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Gynaecology

Review
Treatment options and reproductive outcome for adenomyosis-associated infertility
Ilaria Soave, Jean-Marie Wenger, Nicola Pluchino & Roberto Marci
Pages: 839-849
Published online: 10 Nov 2017
AbstractforTreatment options and reproductive outcome for adenomyosis-associated infertility | Full Text | References | PDF (1.1 MB)
  • 1040 Views
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Oncology

Article
Primary care variability in patients at higher risk for colorectal cancer: evaluation of screening and preventive care practices
John Peabody, Juan-Sebastien Saldivar, Eric Swagel, Steven Fugaro, David Paculdo & Mary Tran
Pages: 851-856
Published online: 21 Jan 2018
AbstractforPrimary care variability in patients at higher risk for colorectal cancer: evaluation of screening and preventive care practices | Full Text | References | PDF (567 KB) | Supplemental
  • 148 Views
  • 4 CrossRef citations
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Article
Neutrophil–lymphocyte ratio, platelet–lymphocyte ratio, neutrophil–platelet score and prognostic nutritional index: do they have prognostic significance in metastatic pancreas cancer?
Mutlu Dogan, Efnan Algin, Zeynep Tugba Guven, Meltem Baykara, Tugba Fahriye Kos, Oznur Bal & Nurullah Zengin
Pages: 857-863
Published online: 15 Dec 2017
AbstractforNeutrophil–lymphocyte ratio, platelet–lymphocyte ratio, neutrophil–platelet score and prognostic nutritional index: do they have prognostic significance in metastatic pancreas cancer? | Full Text | References | PDF (1.1 MB)
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Renal

Report
Evaluation of changes in renal function in PARAMOUNT: a phase III study of maintenance pemetrexed plus best supportive care versus placebo plus best supportive care after induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer
Gary Middleton, Cesare Gridelli, Filippo De Marinis, Jean-Louis Pujol, Martin Reck, Rodryg Ramlau, Barbara Parente, Thierry Pieters, Carla M. Visseren-Grul, Bélen San Antonio, William J. John, Annamaria Hayden Zimmermann, Nadia Chouaki & Luis Paz-Ares
Pages: 865-871
Published online: 27 Mar 2018
AbstractforEvaluation of changes in renal function in PARAMOUNT: a phase III study of maintenance pemetrexed plus best supportive care versus placebo plus best supportive care after induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer | Full Text | References | PDF (673.3 KB)
  • 486 Views
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Gynaecology

Article
Bleeding pattern difference between levonorgestrel intrauterine system and copper intrauterine devices inserted immediately post-abortion: a multicenter, prospective, observational cohort study in Chinese women
Xiaoning Chen, Qianxi Li, Xiaoye Wang, Jing Chen, Wen Lv, Bin Shi, Hong Wang, Jianru Luo & Jian Li
Pages: 873-880
Published online: 07 Feb 2018
AbstractforBleeding pattern difference between levonorgestrel intrauterine system and copper intrauterine devices inserted immediately post-abortion: a multicenter, prospective, observational cohort study in Chinese women | Full Text | References | PDF (950.8 KB) | Supplemental
  • 417 Views
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Endocrinology

Article Commentary
Recombinant luteinizing hormone supplementation to recombinant follicle stimulating hormone therapy in gonadotropin releasing hormone analogue cycles: what is the evidence?
Johnny S. Younis & Neri Laufer
Pages: 881-886
Published online: 15 Jan 2018
AbstractforRecombinant luteinizing hormone supplementation to recombinant follicle stimulating hormone therapy in gonadotropin releasing hormone analogue cycles: what is the evidence? | Full Text | References | PDF (497.4 KB)
  • 1454 Views
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Free Access

Pain

Report
High-concentration topical capsaicin in the management of refractory neuropathic pain in patients with neurofibromatosis type 1: a case series
P. Bardo-Brouard, C. Luizard, L. Valeyrie-Allanore, C. Goujon, B. Do, A. Colin, P. Wolkenstein & M. Paul
Pages: 887-891
Published online: 21 Feb 2018
AbstractforHigh-concentration topical capsaicin in the management of refractory neuropathic pain in patients with neurofibromatosis type 1: a case series | Full Text | References | PDF (554.5 KB)
  • 194 Views
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General medicine

Review
Human abuse potential studies of abuse-deterrent opioids: lessons from oral and intranasal studies with morphine abuse-deterrent, extended-release, injection-molded tablets
Lynn R. Webster, Eugene R. Viscusi, Colville Brown & Jeffrey M. Dayno
Pages: 893-901
Published online: 08 Feb 2018
AbstractforHuman abuse potential studies of abuse-deterrent opioids: lessons from oral and intranasal studies with morphine abuse-deterrent, extended-release, injection-molded tablets | Full Text | References | PDF (1.4 MB)
  • 268 Views
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Oncology

Review
Abiraterone acetate/androgen deprivation therapy combination versus docetaxel/androgen deprivation therapy combination in advanced hormone-sensitive prostate cancer: a network meta-analysis on safety and efficacy
Loay Kassem, Kyrillus S. Shohdy & Omar Abdel-Rahman
Pages: 903-910
Published online: 27 Mar 2018
AbstractforAbiraterone acetate/androgen deprivation therapy combination versus docetaxel/androgen deprivation therapy combination in advanced hormone-sensitive prostate cancer: a network meta-analysis on safety and efficacy | Full Text | References | PDF (691.4 KB)
  • 806 Views
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Review
An overview on the current status of cancer nanomedicines
Nasimudeen R. Jabir, Khalid Anwar, Chelapram K. Firoz, Mohammad Oves, Mohammad Amjad Kamal & Shams Tabrez
Pages: 911-921
Published online: 22 Jan 2018
AbstractforAn overview on the current status of cancer nanomedicines | Full Text | References | PDF (1.2 MB)
  • 517 Views
  • 35 CrossRef citations
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Article
Assessment of the external validity of the American Joint Committee on Cancer 8th staging system for anal carcinoma
Hani Oweira, Anwar Giryes, Meinrad Mannhart, Michael Decker, Rolf Schlumpf & Omar Abdel-Rahman
Pages: 923-929
Published online: 15 Mar 2018
AbstractforAssessment of the external validity of the American Joint Committee on Cancer 8th staging system for anal carcinoma | Full Text | References | PDF (1.9 MB)
  • 131 Views
  • 2 CrossRef citations
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Pain

Article
Patterns of pain medication use in older individuals with cardiovascular disease
Wissam K. Kabbara, Hani Dimassi & Marwan Sheikh-Taha
Pages: 931-934
Published online: 26 Mar 2018
AbstractforPatterns of pain medication use in older individuals with cardiovascular disease | Full Text | References | PDF (380.6 KB)
  • 356 Views
  • 3 CrossRef citations
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Hematology

Article Commentary
Janus kinase inhibition and symptom control in myeloproliferative neoplasms
Prithviraj Bose & Mahesh Swaminathan
Pages: 935-937
Published online: 12 Mar 2018
First Page PreviewforJanus kinase inhibition and symptom control in myeloproliferative neoplasms | Full Text | References | PDF (313.2 KB)
  • 698 Views
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Free Access

Endocrinology

Article Commentary
Exogenous luteinizing hormone supplementation in controlled ovarian stimulation: why, when and to whom?
Ilaria Soave & Roberto Marci
Pages: 939-941
Published online: 05 Mar 2018
First Page PreviewforExogenous luteinizing hormone supplementation in controlled ovarian stimulation: why, when and to whom? | Full Text | References | PDF (309.2 KB)
  • 1019 Views
  • 2 CrossRef citations
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Free Access

Respiratory

Article Commentary
Current and future challenges in pediatric severe asthma
Amelia Licari & Gian Luigi Marseglia
Pages: 943-944
Published online: 08 Mar 2018
CitationforCurrent and future challenges in pediatric severe asthma | Full Text | References | PDF (457.7 KB)
  • 749 Views
  • 9 CrossRef citations
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Hematology

Article
Hemoglobin A2 (HbA2) has a measure of unreliability in diagnosing β-thalassemia trait (β-TT)
Amani M. Al-Amodi, Neda Z. Ghanem, Sumayh A. Aldakeel, Lubna Ibrahim Al Asoom, Nazish Rafique Ahmed, Noor B. Almandil, Zaki A. Naserullah, Sana Al-Jarrash, Mohammed Shakil Akhtar, Sayed AbdulAzeez, Amein K. Al-Ali & J. Francis Borgio
Pages: 945-951
Published online: 15 Feb 2018
AbstractforHemoglobin A2 (HbA2) has a measure of unreliability in diagnosing β-thalassemia trait (β-TT) | Full Text | References | PDF (1.2 MB)
  • 309 Views
  • 12 CrossRef citations
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