Cancer Investigation, Volume 30, Issue 5 (2012)

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Cancer Investigation, Volume 30, Issue 5 (2012)

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CELLULAR AND MOLECULAR BIOLOGY

Article
Apoptosis Deregulation Influences Chemoresistance to Azaguanine in Human Leukemic Cell Lines
A. B. Sarmento-Ribeiro, M. Dourado, A. Paiva, A. Freitas, T. Silva, F. Regateiro & C. R. Oliveira
Pages: 331-342
Published online: 21 Feb 2012
AbstractforApoptosis Deregulation Influences Chemoresistance to Azaguanine in Human Leukemic Cell Lines | Full Text | References | PDF (1,014.4 KB)
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Article
High-Throughput Molecular and Histopathologic Profiling of Tumor Tissue in a Novel Transplantable Model of Murine Neuroblastoma: New Tools for Pediatric Drug Discovery
Jimmy K. Stauffer, Rimas J. Orentas, Erin Lincoln, Tahira Khan, Rosalba Salcedo, Julie A. Hixon, Timothy C. Back, Jun S Wei, Rajesh Patidar, Young Song, Laura Hurd, Maria Tsokos, Edwin W. Lai, Graeme Eisenhofer, William Weiss, Javed Khan & Jon M. Wigginton
Pages: 343-363
Published online: 10 May 2012
AbstractforHigh-Throughput Molecular and Histopathologic Profiling of Tumor Tissue in a Novel Transplantable Model of Murine Neuroblastoma: New Tools for Pediatric Drug Discovery | Full Text | References | PDF (3.3 MB)
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Article
Synthetic Peptides Containing ITIM-Like Domains Block Expression of Inflammatory Mediators and Migration/Invasion of Cancer Cells Through Activation of SHP-1 and PI3K
Jae-Kwan Kim, Sang-Min Lee, Kyoungho Suk & Won-Ha Lee
Pages: 364-371
Published online: 10 May 2012
AbstractforSynthetic Peptides Containing ITIM-Like Domains Block Expression of Inflammatory Mediators and Migration/Invasion of Cancer Cells Through Activation of SHP-1 and PI3K | Full Text | References | PDF (512.5 KB)
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Article
Effects of a Combined Treatment With GPR30 Agonist G-1 and Herceptin on Growth and Gene Expression of Human Breast Cancer Cell Lines
Julia Lubig, Claus Lattrich, Anette Springwald, Julia Häring, Susanne Schüler, Olaf Ortmann & Oliver Treeck
Pages: 372-379
Published online: 02 Apr 2012
AbstractforEffects of a Combined Treatment With GPR30 Agonist G-1 and Herceptin on Growth and Gene Expression of Human Breast Cancer Cell Lines | Full Text | References | PDF (482.4 KB)
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Article
Inhibiting CD164 Expression in Colon Cancer Cell Line HCT116 Leads to Reduced Cancer Cell Proliferation, Mobility, and Metastasis in vitro and in vivo
Jingqun Tang, Liyang Zhang, Xiaoling She, Guangqian Zhou, Fenglei Yu, Juanjuan Xiang & Gang Li
Pages: 380-389
Published online: 12 Mar 2012
AbstractforInhibiting CD164 Expression in Colon Cancer Cell Line HCT116 Leads to Reduced Cancer Cell Proliferation, Mobility, and Metastasis in vitro and in vivo | Full Text | References | PDF (762.7 KB)
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Article
CD133 Negatively Regulates Tumorigenicity via AKT Pathway in Synovial Sarcoma
Taichi Kimura, Lei Wang, Kouichi Tabu, Hiroshi Nishihara, Yuji Mashita, Naoyuki Kikuchi, Mishie Tanino, Hiroaki Hiraga & Shinya Tanaka
Pages: 390-397
Published online: 10 May 2012
AbstractforCD133 Negatively Regulates Tumorigenicity via AKT Pathway in Synovial Sarcoma | Full Text | References | PDF (1.8 MB)
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Article
Expression of Cysteine Protease Cathepsin L is Increased in Endometrial Cancer and Correlates With Expression of Growth Regulatory Genes
Maciej Skrzypczak, Anette Springwald, Claus Lattrich, Julia Häring, Susanne Schüler, Olaf Ortmann & Oliver Treeck
Pages: 398-403
Published online: 27 Mar 2012
AbstractforExpression of Cysteine Protease Cathepsin L is Increased in Endometrial Cancer and Correlates With Expression of Growth Regulatory Genes | Full Text | References | PDF (297.8 KB)
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Article
Centroblastic Diffuse Large B Cell Lymphoma Displays Distinct Expression Pattern and Prognostic Role of Apoptosis Resistance Related Proteins
Roberta Soares Faccion, Lidia Maria Magalhães Rezende, Sérgio de Oliveira Romano, Ricardo de Sá Bigni, Gelcio Luiz Quintella Mendes & Raquel Ciuvalschi Maia
Pages: 404-414
Published online: 10 May 2012
AbstractforCentroblastic Diffuse Large B Cell Lymphoma Displays Distinct Expression Pattern and Prognostic Role of Apoptosis Resistance Related Proteins | Full Text | References | PDF (779.5 KB)
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CLINICAL TRANSLATIONAL THERAPEUTICS

Article
MG98, a Second-Generation DNMT1 Inhibitor, in the Treatment of Advanced Renal Cell Carcinoma
Robert J. Amato, Joe Stephenson, Sebastien Hotte, John Nemunaitis, Karl Bélanger, Gregory Reid & Robert E. Martell
Pages: 415-421
Published online: 10 May 2012
AbstractforMG98, a Second-Generation DNMT1 Inhibitor, in the Treatment of Advanced Renal Cell Carcinoma | Full Text | References | PDF (190.5 KB)
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Article
Functional Analysis of the Putative Tumor Suppressor PTPRD in Neuroblastoma Cells
O. Clark, F. Schmidt, C. H. Coles, V. Tchetchelnitski & A. W. Stoker
Pages: 422-432
Published online: 10 May 2012
AbstractforFunctional Analysis of the Putative Tumor Suppressor PTPRD in Neuroblastoma Cells | Full Text | References | PDF (1.7 MB)
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REVIEW

Article
Primary and Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancer: An Update
Ayodele Ayoola, Amit Barochia, Kiran Belani & Chandra P. Belani
Pages: 433-446
Published online: 10 May 2012
AbstractforPrimary and Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancer: An Update | Full Text | References | PDF (296.8 KB)
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