Drug Delivery, Volume 24, Issue 1 (2017)

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Drug Delivery, Volume 24, Issue 1 (2017)

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Critical Review

Review
Design of amphotericin B oral formulation for antifungal therapy
Min Liu, Meiwan Chen & Zhiwen Yang
Pages: 1-9
Published online: 03 Feb 2017
AbstractforDesign of amphotericin B oral formulation for antifungal therapy | Full Text | References | PDF (421.5 KB)
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Open Access

Research Articles

Article
A microemulsion co-loaded with Schizandrin A–docetaxel enhances esophageal carcinoma treatment through overcoming multidrug resistance
Xiangyu Su, Chanchan Gao, Fangfang Shi, Xiaoyao Feng, Lin Liu, Ding Qu & Cailian Wang
Pages: 10-19
Published online: 03 Feb 2017
AbstractforA microemulsion co-loaded with Schizandrin A–docetaxel enhances esophageal carcinoma treatment through overcoming multidrug resistance | Full Text | References | PDF (1.8 MB)
  • 2616 Views
  • 18 CrossRef citations
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Open Access
Article
Asialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma
Sandhya Pranatharthiharan, Mitesh D. Patel, Vinod C. Malshe, Vaishali Pujari, Ajit Gorakshakar, Manisha Madkaikar, Kanjaksha Ghosh & Padma V. Devarajan
Pages: 20-29
Published online: 03 Feb 2017
AbstractforAsialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma | Full Text | References | PDF (1.2 MB) | Supplemental
  • 6371 Views
  • 67 CrossRef citations
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Open Access
Article
Hyaluronic acid-modified didecyldimethylammonium bromide/ d-a-tocopheryl polyethylene glycol succinate mixed micelles for delivery of baohuoside I against non-small cell lung cancer: in vitro and in vivo evaluation
Hongmei Yan, Jie Song, Xiaobin Jia & Zhenhai Zhang
Pages: 30-39
Published online: 03 Feb 2017
AbstractforHyaluronic acid-modified didecyldimethylammonium bromide/ d-a-tocopheryl polyethylene glycol succinate mixed micelles for delivery of baohuoside I against non-small cell lung cancer: in vitro and in vivo evaluation | Full Text | References | PDF (1.9 MB)
  • 2422 Views
  • 28 CrossRef citations
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Open Access
Article
Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats
Mahasen A. Radwan, Bushra T. AlQuadeib, Lidija Šiller, Matthew C. Wright & Benjamin Horrocks
Pages: 40-50
Published online: 03 Feb 2017
AbstractforOral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats | Full Text | References | PDF (1 MB)
  • 5880 Views
  • 67 CrossRef citations
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Open Access
Article
A green approach to dual-drug nanoformulations with targeting and synergistic effects for cancer therapy
Shichao Wu, Xiangrui Yang, Yue Lu, Zhongxiong Fan, Yang Li, Yuan Jiang & Zhenqing Hou
Pages: 51-60
Published online: 03 Feb 2017
AbstractforA green approach to dual-drug nanoformulations with targeting and synergistic effects for cancer therapy | Full Text | References | PDF (1.8 MB) | Supplemental
  • 3674 Views
  • 27 CrossRef citations
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Open Access
Article
Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage
Kiran S. Avadhani, Jyothsna Manikkath, Mradul Tiwari, Misra Chandrasekhar, Ashok Godavarthi, Shimoga M. Vidya, Raghu C. Hariharapura, Guruprasad Kalthur, Nayanabhirama Udupa & Srinivas Mutalik
Pages: 61-74
Published online: 03 Feb 2017
AbstractforSkin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage | Full Text | References | PDF (721.4 KB)
  • 15026 Views
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Open Access
Article
In vivo synergistic anti-tumor effect of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma
YanXin Yu, Shan Xu, Hong You, YinJie Zhang, Bo Yang, XiaoYang Sun, LingLin Yang, Yue Chen, ShaoZhi Fu & JingBo Wu
Pages: 75-82
Published online: 03 Feb 2017
AbstractforIn vivo synergistic anti-tumor effect of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma | Full Text | References | PDF (1.7 MB)
  • 2737 Views
  • 28 CrossRef citations
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Open Access

Review Article

Review
A novel strategy to achieve effective drug delivery: exploit cells as carrier combined with nanoparticles
Liang Pang, Chun Zhang, Jing Qin, Limei Han, Ruixiang Li, Chao Hong, Huining He & Jianxin Wang
Pages: 83-91
Published online: 03 Feb 2017
AbstractforA novel strategy to achieve effective drug delivery: exploit cells as carrier combined with nanoparticles | Full Text | References | PDF (1.2 MB)
  • 6965 Views
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Open Access

Research Articles

Article
Research on the comparison of the demethylvancomycin’s diffusion–deposition characteristics in the ocular solid tissues of sustained subtenon drug delivery with subconjunctival injection
Yi-Qin Duan, Ye-Zhen Yang, Xue-Tao Huang & Ding Lin
Pages: 92-98
Published online: 03 Feb 2017
AbstractforResearch on the comparison of the demethylvancomycin’s diffusion–deposition characteristics in the ocular solid tissues of sustained subtenon drug delivery with subconjunctival injection | Full Text | References | PDF (700.3 KB)
  • 1063 Views
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Open Access
Article
Optimizing novel penetration enhancing hybridized vesicles for augmenting the in-vivo effect of an anti-glaucoma drug
Sarah S. Naguib, Rania M. Hathout & Samar Mansour
Pages: 99-108
Published online: 03 Feb 2017
AbstractforOptimizing novel penetration enhancing hybridized vesicles for augmenting the in-vivo effect of an anti-glaucoma drug | Full Text | References | PDF (879.4 KB) | Supplemental
  • 2038 Views
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Open Access
Article
High drug payload curcumin nanosuspensions stabilized by mPEG-DSPE and SPC: in vitro and in vivo evaluation
Jingyi Hong, Yingying Liu, Yao Xiao, Xiaofeng Yang, Wenjing Su, Mingzhu Zhang, Yonghong Liao, Haixue Kuang & Xiangtao Wang
Pages: 109-120
Published online: 03 Feb 2017
AbstractforHigh drug payload curcumin nanosuspensions stabilized by mPEG-DSPE and SPC: in vitro and in vivo evaluation | Full Text | References | PDF (2.4 MB)
  • 2698 Views
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Open Access

Original Article

Article
Cholesterol–PEG comodified poly (N-butyl) cyanoacrylate nanoparticles for brain delivery: in vitro and in vivo evaluations
Xiao Hu, Feifei Yang, Yonghong Liao, Lin Li & Lan Zhang
Pages: 121-132
Published online: 03 Feb 2017
AbstractforCholesterol–PEG comodified poly (N-butyl) cyanoacrylate nanoparticles for brain delivery: in vitro and in vivo evaluations | Full Text | References | PDF (873.5 KB) | Supplemental
  • 2330 Views
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Open Access

Research Article

Article
Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis
Maha M. A. Nasra, Heba M. Khiri, Heba A. Hazzah & Ossama Y. Abdallah
Pages: 133-142
Published online: 03 Feb 2017
AbstractforFormulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis | Full Text | References | PDF (749.4 KB)
  • 8422 Views
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Original Articles

Article
Simultaneous monitoring of the drug release and antitumor effect of a novel drug delivery system-MWCNTs/DOX/TC
Xia Dong, Zhiting Sun, Xiaoxiao Wang, Dunwan Zhu, Lanxia Liu & Xigang Leng
Pages: 143-151
Published online: 03 Feb 2017
AbstractforSimultaneous monitoring of the drug release and antitumor effect of a novel drug delivery system-MWCNTs/DOX/TC | Full Text | References | PDF (2.2 MB)
  • 2569 Views
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Open Access
Article
Docosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion
Rajshree L. Shinde & Padma V. Devarajan
Pages: 152-161
Published online: 03 Feb 2017
AbstractforDocosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion | Full Text | References | PDF (787 KB) | Supplemental
  • 4185 Views
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Review Article

Review
Polyphenols delivery by polymeric materials: challenges in cancer treatment
Orazio Vittorio, Manuela Curcio, Monica Cojoc, Gerardo F. Goya, Silke Hampel, Francesca Iemma, Anna Dubrovska & Giuseppe Cirillo
Pages: 162-180
Published online: 03 Feb 2017
AbstractforPolyphenols delivery by polymeric materials: challenges in cancer treatment | Full Text | References | PDF (672.1 KB)
  • 4439 Views
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Research Articles

Article
Contribution of both olfactory and systemic pathways for brain targeting of nimodipine-loaded lipo-pluronics micelles: in vitro characterization and in vivo biodistribution study after intranasal and intravenous delivery
Hassan M. Rashed, Rehab N. Shamma & Emad B. Basalious
Pages: 181-187
Published online: 03 Feb 2017
AbstractforContribution of both olfactory and systemic pathways for brain targeting of nimodipine-loaded lipo-pluronics micelles: in vitro characterization and in vivo biodistribution study after intranasal and intravenous delivery | Full Text | References | PDF (729.7 KB)
  • 1897 Views
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Open Access
Article
Respirable controlled release polymeric colloid (RCRPC) of bosentan for the management of pulmonary hypertension: in vitro aerosolization, histological examination and in vivo pulmonary absorption
Lydia A. Hanna, Emad B. Basalious & Omaima N. ELGazayerly
Pages: 188-198
Published online: 03 Feb 2017
AbstractforRespirable controlled release polymeric colloid (RCRPC) of bosentan for the management of pulmonary hypertension: in vitro aerosolization, histological examination and in vivo pulmonary absorption | Full Text | References | PDF (1.3 MB)
  • 1990 Views
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Open Access
Article
Formation of multimeric antibodies for self-delivery of active monomers
Yaron Dekel, Yossy Machluf, Tal Gefen, Gennady Eidelshtein, Alexander Kotlyar, Yaron Bram, Ehud Shahar, Farah Reslane, Elina Aizenshtein & Jacob Pitcovski
Pages: 199-208
Published online: 03 Feb 2017
AbstractforFormation of multimeric antibodies for self-delivery of active monomers | Full Text | References | PDF (1.2 MB)
  • 2196 Views
  • 5 CrossRef citations
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Open Access
Article
Cholesterol-conjugated poly(D, L-lactide)-based micelles as a nanocarrier system for effective delivery of curcumin in cancer therapy
Preeti Kumari, Omkara Swami Muddineti, Sri Vishnu Kiran Rompicharla, Pratyusha Ghanta, Adithya Karthik B B N, Balaram Ghosh & Swati Biswas
Pages: 209-223
Published online: 03 Feb 2017
AbstractforCholesterol-conjugated poly(D, L-lactide)-based micelles as a nanocarrier system for effective delivery of curcumin in cancer therapy | Full Text | References | PDF (3.4 MB) | Supplemental
  • 3534 Views
  • 63 CrossRef citations
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Open Access
Article
Enhanced oral bioavailability and anticancer efficacy of fisetin by encapsulating as inclusion complex with HPβCD in polymeric nanoparticles
Amrita Kadari, Sagarika Gudem, Hitesh Kulhari, Murali Mohan Bhandi, Roshan M. Borkar, Venkata Ramana Murthy Kolapalli & Ramakrishna Sistla
Pages: 224-232
Published online: 03 Feb 2017
AbstractforEnhanced oral bioavailability and anticancer efficacy of fisetin by encapsulating as inclusion complex with HPβCD in polymeric nanoparticles | Full Text | References | PDF (954.9 KB) | Supplemental
  • 6512 Views
  • 78 CrossRef citations
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Open Access
Article
Orally delivered polycurcumin responsive to bacterial reduction for targeted therapy of inflammatory bowel disease
Hongzhi Qiao, Dong Fang, Jing Chen, Yuan Sun, Chen Kang, Liuqing Di, Junsong Li, Zhipeng Chen, Jun Chen & Yahan Gao
Pages: 233-242
Published online: 03 Feb 2017
AbstractforOrally delivered polycurcumin responsive to bacterial reduction for targeted therapy of inflammatory bowel disease | Full Text | References | PDF (1.4 MB)
  • 3609 Views
  • 39 CrossRef citations
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Open Access
Article
Passive targeting and lung tolerability of enoxaparin microspheres for a sustained antithrombotic activity in rats
Shaimaa S. Ibrahim, Rihab Osman, Nahed D. Mortada, Ahmed-Shawky Geneidy & Gehanne A. S. Awad
Pages: 243-251
Published online: 03 Feb 2017
AbstractforPassive targeting and lung tolerability of enoxaparin microspheres for a sustained antithrombotic activity in rats | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1497 Views
  • 6 CrossRef citations
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Open Access
Article
Nanotransfersomes-loaded thermosensitive in situ gel as a rectal delivery system of tizanidine HCl: preparation, in vitro and in vivo performance
Fatma A. Moawad, Adel A. Ali & Heba F. Salem
Pages: 252-260
Published online: 03 Feb 2017
AbstractforNanotransfersomes-loaded thermosensitive in situ gel as a rectal delivery system of tizanidine HCl: preparation, in vitro and in vivo performance | Full Text | References | PDF (996.2 KB)
  • 3924 Views
  • 57 CrossRef citations
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Open Access
Article
Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles
Jian Hou, E. Sun, Zhen-Hai Zhang, Jing Wang, Lei Yang, Li Cui, Zhong-Cheng Ke, Xiao-Bin Tan, Xiao-Bin Jia & Huixia Lv
Pages: 261-269
Published online: 06 Feb 2017
AbstractforImproved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles | Full Text | References | PDF (1.7 MB)
  • 3403 Views
  • 45 CrossRef citations
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Open Access
Article
Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix
Yang Guo, Ting Zhong, Xiao-Chuan Duan, Shuang Zhang, Xin Yao, Yi-Fan Yin, Dan Huang, Wei Ren, Qiang Zhang & Xuan Zhang
Pages: 270-277
Published online: 06 Feb 2017
AbstractforImproving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix | Full Text | References | PDF (2.4 MB) | Supplemental
  • 3029 Views
  • 20 CrossRef citations
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Open Access

Original Article

Article
Development and characterization of polymer-coated liposomes for vaginal delivery of sildenafil citrate
Hanan Refai, Doaa Hassan & Rehab Abdelmonem
Pages: 278-288
Published online: 06 Feb 2017
AbstractforDevelopment and characterization of polymer-coated liposomes for vaginal delivery of sildenafil citrate | Full Text | References | PDF (1.2 MB)
  • 5390 Views
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Review Article

Review
Seek and destroy: targeted adeno-associated viruses for gene delivery to hepatocellular carcinoma
Bijay Dhungel, Aparna Jayachandran, Christopher J. Layton & Jason C. Steel
Pages: 289-299
Published online: 06 Feb 2017
AbstractforSeek and destroy: targeted adeno-associated viruses for gene delivery to hepatocellular carcinoma | Full Text | References | PDF (739.9 KB)
  • 3741 Views
  • 16 CrossRef citations
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Research Article

Article
Preparation of endostatin-loaded chitosan nanoparticles and evaluation of the antitumor effect of such nanoparticles on the Lewis lung cancer model
Rui-Lin Ding, Fang Xie, Yue Hu, Shao-Zhi Fu, Jing-Bo Wu, Juan Fan, Wen-Feng He, Yu He, Ling-Lin Yang, Sheng Lin & Qing-Lian Wen
Pages: 300-308
Published online: 06 Feb 2017
AbstractforPreparation of endostatin-loaded chitosan nanoparticles and evaluation of the antitumor effect of such nanoparticles on the Lewis lung cancer model | Full Text | References | PDF (2 MB)
  • 2660 Views
  • 28 CrossRef citations
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Original Articles

Article
Ocular ketoconazole-loaded proniosomal gels: formulation, ex vivo corneal permeation and in vivo studies
Ghada A. Abdelbary, Maha M. Amin & Mohamed Y. Zakaria
Pages: 309-319
Published online: 06 Feb 2017
AbstractforOcular ketoconazole-loaded proniosomal gels: formulation, ex vivo corneal permeation and in vivo studies | Full Text | References | PDF (819.1 KB)
  • 3571 Views
  • 62 CrossRef citations
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Open Access
Article
The development of mechanically formed stable nanobubbles intended for sonoporation-mediated gene transfection
Rodi Abdalkader, Shigeru Kawakami, Johan Unga, Yuriko Higuchi, Ryo Suzuki, Kazuo Maruyama, Fumiyoshi Yamashita & Mitsuru Hashida
Pages: 320-327
Published online: 06 Feb 2017
AbstractforThe development of mechanically formed stable nanobubbles intended for sonoporation-mediated gene transfection | Full Text | References | PDF (1.8 MB) | Supplemental
  • 2586 Views
  • 22 CrossRef citations
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Article
Investigation of the effect of solubility increase at the main absorption site on bioavailability of BCS class II drug (risperidone) using liquisolid technique
Ahmed Khames
Pages: 328-338
Published online: 06 Feb 2017
AbstractforInvestigation of the effect of solubility increase at the main absorption site on bioavailability of BCS class II drug (risperidone) using liquisolid technique | Full Text | References | PDF (1.2 MB)
  • 6234 Views
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Research Articles

Article
PCM and TAT co-modified liposome with improved myocardium delivery: in vitro and in vivo evaluations
Xin Wang, Hua Huang, Liangke Zhang, Yan Bai & Huali Chen
Pages: 339-345
Published online: 06 Feb 2017
AbstractforPCM and TAT co-modified liposome with improved myocardium delivery: in vitro and in vivo evaluations | Full Text | References | PDF (1.1 MB)
  • 2336 Views
  • 19 CrossRef citations
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Open Access
Article
Successful delivery of docetaxel to rat brain using experimentally developed nanoliposome: a treatment strategy for brain tumor
Tapan Kumar Shaw, Dipika Mandal, Goutam Dey, Murari Mohan Pal, Paramita Paul, Samrat Chakraborty, Kazi Asraf Ali, Biswajit Mukherjee, Amal Kumar Bandyopadhyay & Mahitosh Mandal
Pages: 346-357
Published online: 06 Feb 2017
AbstractforSuccessful delivery of docetaxel to rat brain using experimentally developed nanoliposome: a treatment strategy for brain tumor | Full Text | References | PDF (1.6 MB) | Supplemental
  • 3483 Views
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Review Article

Review
Nanocarriers as treatment modalities for hypertension
Tausif Alam, Saba Khan, Bharti Gaba, Md. Faheem Haider, Sanjula Baboota & Javed Ali
Pages: 358-369
Published online: 06 Feb 2017
AbstractforNanocarriers as treatment modalities for hypertension | Full Text | References | PDF (477.9 KB)
  • 8895 Views
  • 53 CrossRef citations
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Research Articles

Article
Diclofenac sodium ion exchange resin complex loaded melt cast films for sustained release ocular delivery
Goutham R. Adelli, Sai Prachetan Balguri, Prakash Bhagav, Vijayasankar Raman & Soumyajit Majumdar
Pages: 370-379
Published online: 06 Feb 2017
AbstractforDiclofenac sodium ion exchange resin complex loaded melt cast films for sustained release ocular delivery | Full Text | References | PDF (722.2 KB) | Supplemental
  • 2626 Views
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Open Access
Article
Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches
Vieri Piazzini, Elena Monteforte, Cristina Luceri, Elisabetta Bigagli, Anna Rita Bilia & Maria Camilla Bergonzi
Pages: 380-390
Published online: 06 Feb 2017
AbstractforNanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches | Full Text | References | PDF (700.3 KB)
  • 5313 Views
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Article
Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles
YueLong Wang, Min Wu, Lei Gu, XiaoLing Li, Jun He, LiangXue Zhou, Aiping Tong, Juan Shi, HongYan Zhu, JianGuo Xu & Gang Guo
Pages: 391-401
Published online: 06 Feb 2017
AbstractforEffective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles | Full Text | References | PDF (3.3 MB)
  • 3685 Views
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Original Article

Article
Targeting delivery of simvastatin using ICAM-1 antibody-conjugated nanostructured lipid carriers for acute lung injury therapy
Shu-Juan Li, Xiao-Juan Wang, Jing-Bo Hu, Xu-Qi Kang, Li Chen, Xiao-Ling Xu, Xiao-Ying Ying, Sai-Ping Jiang & Yong-Zhong Du
Pages: 402-413
Published online: 06 Feb 2017
AbstractforTargeting delivery of simvastatin using ICAM-1 antibody-conjugated nanostructured lipid carriers for acute lung injury therapy | Full Text | References | PDF (2.7 MB) | Supplemental
  • 2253 Views
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Research Article

Article
In vitro and in vivo investigation for optimization of niosomal ability for sustainment and bioavailability enhancement of diltiazem after nasal administration
H. O. Ammar, M. Haider, M. Ibrahim & N. M. El Hoffy
Pages: 414-421
Published online: 06 Feb 2017
AbstractforIn vitro and in vivo investigation for optimization of niosomal ability for sustainment and bioavailability enhancement of diltiazem after nasal administration | Full Text | References | PDF (450.1 KB)
  • 3649 Views
  • 40 CrossRef citations
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Original Articles

Article
Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies
Tao Yi, Dandan Tang, Fan Wang, Jiqiong Zhang, Jiao Zhang, Jirui Wang, Xiaoyu Xu & Jifen Zhang
Pages: 422-429
Published online: 06 Feb 2017
AbstractforEnhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies | Full Text | References | PDF (569.3 KB) | Supplemental
  • 3114 Views
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Article
The protective effect of lipid emulsion in preventing bupivacaine-induced mitochondrial injury and apoptosis of H9C2 cardiomyocytes
Zhe Chen, Zhousheng Jin, Yun Xia, Shishi Zhao, Xuzhong Xu, Thomas J. Papadimos & Quanguang Wang
Pages: 430-436
Published online: 06 Feb 2017
AbstractforThe protective effect of lipid emulsion in preventing bupivacaine-induced mitochondrial injury and apoptosis of H9C2 cardiomyocytes | Full Text | References | PDF (812.8 KB)
  • 1690 Views
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Research Article

Article
Plasma concentration of metformin and dexamethasone after administration through Osseogate
Hong-Kyun Kim & Young-Seok Park
Pages: 437-442
Published online: 06 Feb 2017
AbstractforPlasma concentration of metformin and dexamethasone after administration through Osseogate | Full Text | References | PDF (525.4 KB)
  • 1626 Views
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Original Article

Article
PLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies
Ying Liu, Xin Wu, Yushuai Mi, Bimeng Zhang, Shengying Gu, Gaolin Liu & Xiaoyu Li
Pages: 443-451
Published online: 06 Feb 2017
AbstractforPLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies | Full Text | References | PDF (1.2 MB)
  • 3712 Views
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Research Articles

Article
Controllable continuous sub-tenon drug delivery of dexamethasone disodium phosphate to ocular posterior segment in rabbit
Xuetao Huang, Shaogang Liu, Yezhen Yang, Yiqin Duan & Ding Lin
Pages: 452-458
Published online: 06 Feb 2017
AbstractforControllable continuous sub-tenon drug delivery of dexamethasone disodium phosphate to ocular posterior segment in rabbit | Full Text | References | PDF (465.2 KB)
  • 1650 Views
  • 10 CrossRef citations
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Article
In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy
Can Huang, Na-Mei Li, Pei Gao, Sa Yang, Qian Ning, Wen Huang, Zhi-Ping Li, Peng-Ju Ye, Li Xiang, Dong-Xiu He, Xiang-Wen Tan & Cui-Yun Yu
Pages: 459-466
Published online: 21 Feb 2017
AbstractforIn vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy | Full Text | References | PDF (1.1 MB)
  • 2206 Views
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Original Article

Article
Transdermal delivery of isoniazid and rifampin in guinea pigs by electro-phonophoresis
Suting Chen, Yi Han, Daping Yu, Fengmin Huo, Fen Wang, Yunxu Li, Lingling Dong, Zhidong Liu & Hairong Huang
Pages: 467-470
Published online: 09 Feb 2017
AbstractforTransdermal delivery of isoniazid and rifampin in guinea pigs by electro-phonophoresis | Full Text | References | PDF (267.2 KB)
  • 1598 Views
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Research Articles

Article
A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo
Shuai He, Bohong Cen, Lumin Liao, Zhen Wang, Yixin Qin, Zhuomin Wu, Wenjie Liao, Zhongyi Zhang & Aimin Ji
Pages: 471-481
Published online: 09 Feb 2017
AbstractforA tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo | Full Text | References | PDF (3.3 MB) | Supplemental
  • 3945 Views
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Article
Synthesis of sericin-based conjugates by click chemistry: enhancement of sunitinib bioavailability and cell membrane permeation
Luca Scrivano, Domenico Iacopetta, Maria Stefania Sinicropi, Carmela Saturnino, Pasquale Longo, Ortensia Ilaria Parisi & Francesco Puoci
Pages: 482-490
Published online: 09 Feb 2017
AbstractforSynthesis of sericin-based conjugates by click chemistry: enhancement of sunitinib bioavailability and cell membrane permeation | Full Text | References | PDF (866.3 KB)
  • 2394 Views
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Article
Mathematical modeling of intraperitoneal drug delivery: simulation of drug distribution in a single tumor nodule
Margo Steuperaert, Giuseppe Falvo D’Urso Labate, Charlotte Debbaut, Olivier De Wever, Christian Vanhove, Wim Ceelen & Patrick Segers
Pages: 491-501
Published online: 09 Feb 2017
AbstractforMathematical modeling of intraperitoneal drug delivery: simulation of drug distribution in a single tumor nodule | Full Text | References | PDF (1.2 MB) | Supplemental
  • 4590 Views
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Article
Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration
Fakhar ud Din, Ju Yeon Choi, Dong Wuk Kim, Omer Mustapha, Dong Shik Kim, Raj Kumar Thapa, Sae Kwang Ku, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim & Han-Gon Choi
Pages: 502-510
Published online: 09 Feb 2017
AbstractforIrinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration | Full Text | References | PDF (1.7 MB)
  • 2917 Views
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Article
Magnetically triggered drug release from nanoparticles and its applications in anti-tumor treatment
Xin Hua, Qin Yang, Zhimin Dong, Jiashuo Zhang, Wanjiang Zhang, Qiudong Wang, Shengnan Tan & Hugh D. C. Smyth
Pages: 511-518
Published online: 09 Feb 2017
AbstractforMagnetically triggered drug release from nanoparticles and its applications in anti-tumor treatment | Full Text | References | PDF (1.8 MB)
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Article
Surface density of polyarginine influence the size, zeta potential, cellular uptake and tissue distribution of the nanostructured lipid carrier
Mingshuang Sun, Zhihong Zhu, Huixin Wang, Cuiyan Han, Dandan Liu, Lei Tian, Xinggang Yang & Weisan Pan
Pages: 519-526
Published online: 09 Feb 2017
AbstractforSurface density of polyarginine influence the size, zeta potential, cellular uptake and tissue distribution of the nanostructured lipid carrier | Full Text | References | PDF (1.7 MB) | Supplemental
  • 2361 Views
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Article
Anhydrous reverse micelle nanoparticles: new strategy to overcome sedimentation instability of peptide-containing pressurized metered-dose inhalers
Zhengwei Huang, Han Wu, Beibei Yang, Longkai Chen, Ying Huang, Guilan Quan, Chune Zhu, Xing Li, Xin Pan & Chuanbin Wu
Pages: 527-538
Published online: 09 Feb 2017
AbstractforAnhydrous reverse micelle nanoparticles: new strategy to overcome sedimentation instability of peptide-containing pressurized metered-dose inhalers | Full Text | References | PDF (1.6 MB)
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Review

Review
Basic concepts and recent advances in nanogels as carriers for medical applications
Iordana Neamtu, Alina Gabriela Rusu, Alina Diaconu, Loredana Elena Nita & Aurica P. Chiriac
Pages: 539-557
Published online: 09 Feb 2017
AbstractforBasic concepts and recent advances in nanogels as carriers for medical applications | Full Text | References | PDF (1.6 MB)
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Original Article

Article
Marked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice
Chisayo Kozuka, Chigusa Shimizu-Okabe, Chitoshi Takayama, Kaku Nakano, Hidetaka Morinaga, Ayano Kinjo, Kotaro Fukuda, Asuka Kamei, Akihito Yasuoka, Takashi Kondo, Keiko Abe, Kensuke Egashira & Hiroaki Masuzaki
Pages: 558-568
Published online: 09 Feb 2017
AbstractforMarked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice | Full Text | References | PDF (1.3 MB) | Supplemental
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Review Article

Review
pH-Responsive carriers for oral drug delivery: challenges and opportunities of current platforms
Lin Liu, WenDong Yao, YueFeng Rao, XiaoYang Lu & JianQing Gao
Pages: 569-581
Published online: 14 Feb 2017
AbstractforpH-Responsive carriers for oral drug delivery: challenges and opportunities of current platforms | Full Text | References | PDF (490.8 KB)
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Research Articles

Article
In vitro–ex vivo correlations between a cell-laden hydrogel and mucosal tissue for screening composite delivery systems
Anna K. Blakney, Adam B. Little, Yonghou Jiang & Kim A. Woodrow
Pages: 582-590
Published online: 21 Feb 2017
AbstractforIn vitro–ex vivo correlations between a cell-laden hydrogel and mucosal tissue for screening composite delivery systems | Full Text | References | PDF (990.1 KB) | Supplemental
  • 1463 Views
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Article
Influence of PEG coating on the oral bioavailability of gold nanoparticles in rats
Ahmed Alalaiwe, Georgia Roberts, Paul Carpinone, John Munson & Stephen Roberts
Pages: 591-598
Published online: 21 Feb 2017
AbstractforInfluence of PEG coating on the oral bioavailability of gold nanoparticles in rats | Full Text | References | PDF (727.7 KB)
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Original Article

Article
Antitumor activity of intratracheal inhalation of temozolomide (TMZ) loaded into gold nanoparticles and/or liposomes against urethane-induced lung cancer in BALB/c mice
Mohamed A. Hamzawy, Amira M. Abo-youssef, Heba F. Salem & Sameh A. Mohammed
Pages: 599-607
Published online: 26 Feb 2017
AbstractforAntitumor activity of intratracheal inhalation of temozolomide (TMZ) loaded into gold nanoparticles and/or liposomes against urethane-induced lung cancer in BALB/c mice | Full Text | References | PDF (1.5 MB)
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Review Article

Review
“Fusion and binding inhibition” key target for HIV-1 treatment and pre-exposure prophylaxis: targets, drug delivery and nanotechnology approaches
Tanushree Malik, Gaurav Chauhan, Goutam Rath, R. S. R. Murthy & Amit K. Goyal
Pages: 608-621
Published online: 26 Feb 2017
Abstractfor“Fusion and binding inhibition” key target for HIV-1 treatment and pre-exposure prophylaxis: targets, drug delivery and nanotechnology approaches | Full Text | References | PDF (1.8 MB) | Supplemental
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Research Articles

Article
Sustained release ivermectin-loaded solid lipid dispersion for subcutaneous delivery: in vitro and in vivo evaluation
Mengmeng Lu, Dan Xiong, Weiwei Sun, Tong Yu, Zixia Hu, Jiafeng Ding, Yunpeng Cai, Shizhuang Yang & Baoliang Pan
Pages: 622-631
Published online: 10 Mar 2017
AbstractforSustained release ivermectin-loaded solid lipid dispersion for subcutaneous delivery: in vitro and in vivo evaluation | Full Text | References | PDF (672.2 KB) | Supplemental
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Article
Characterization and evaluation of a self-microemulsifying drug delivery system containing tectorigenin, an isoflavone with low aqueous solubility and poor permeability
Yunrong Zhang, Li He, Shanlan Yue, Qingting Huang, Yuhong Zhang & Junyi Yang
Pages: 632-640
Published online: 10 Mar 2017
AbstractforCharacterization and evaluation of a self-microemulsifying drug delivery system containing tectorigenin, an isoflavone with low aqueous solubility and poor permeability | Full Text | References | PDF (336.6 KB)
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Article
Thermosensitive porphyrin-incorporated hydrogel with four-arm PEG-PCL copolymer (II): doxorubicin loaded hydrogel as a dual fluorescent drug delivery system for simultaneous imaging tracking in vivo
Xia Dong, Hongli Chen, Jingwen Qin, Chang Wei, Jie Liang, Tianjun Liu, Deling Kong & Feng Lv
Pages: 641-650
Published online: 10 Mar 2017
AbstractforThermosensitive porphyrin-incorporated hydrogel with four-arm PEG-PCL copolymer (II): doxorubicin loaded hydrogel as a dual fluorescent drug delivery system for simultaneous imaging tracking in vivo | Full Text | References | PDF (2.1 MB)
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Original Article

Article
Bacterial magnetic particles improve testes-mediated transgene efficiency in mice
Chao Wang, Guanghong Sun, Ye Wang, Nana Kong, Yafei Chi, Leilei Yang, Qiliang Xin, Zhen Teng, Xu Wang, Yujun Wen, Ying Li & Guoliang Xia
Pages: 651-659
Published online: 10 Mar 2017
AbstractforBacterial magnetic particles improve testes-mediated transgene efficiency in mice | Full Text | References | PDF (1.7 MB)
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Research Articles

Article
Honokiol-loaded polymeric nanoparticles: an active targeting drug delivery system for the treatment of nasopharyngeal carcinoma
Bo Yang, XiaoLing Ni, LongXia Chen, Heng Zhang, PeiRong Ren, Yue Feng, Yue Chen, ShaoZhi Fu & JingBo Wu
Pages: 660-669
Published online: 03 Apr 2017
AbstractforHonokiol-loaded polymeric nanoparticles: an active targeting drug delivery system for the treatment of nasopharyngeal carcinoma | Full Text | References | PDF (2.2 MB)
  • 2202 Views
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Article
Enhanced cytotoxic effect of camptothecin nanosponges in anaplastic thyroid cancer cells in vitro and in vivo on orthotopic xenograft tumors
Casimiro Luca Gigliotti, Benedetta Ferrara, Sergio Occhipinti, Elena Boggio, Giuseppina Barrera, Stefania Pizzimenti, Mirella Giovarelli, Roberto Fantozzi, Annalisa Chiocchetti, Monica Argenziano, Nausicaa Clemente, Francesco Trotta, Caterina Marchiò, Laura Annaratone, Renzo Boldorini, Umberto Dianzani, Roberta Cavalli & Chiara Dianzani
Pages: 670-680
Published online: 03 Apr 2017
AbstractforEnhanced cytotoxic effect of camptothecin nanosponges in anaplastic thyroid cancer cells in vitro and in vivo on orthotopic xenograft tumors | Full Text | References | PDF (1.5 MB) | Supplemental
  • 2281 Views
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Article
Polydopamine and peptide decorated doxorubicin-loaded mesoporous silica nanoparticles as a targeted drug delivery system for bladder cancer therapy
Yi Wei, Li Gao, Lu Wang, Lin Shi, Erdong Wei, Baotong Zhou, Li Zhou & Bo Ge
Pages: 681-691
Published online: 17 Apr 2017
AbstractforPolydopamine and peptide decorated doxorubicin-loaded mesoporous silica nanoparticles as a targeted drug delivery system for bladder cancer therapy | Full Text | References | PDF (2.5 MB) | Supplemental
  • 7828 Views
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Article
Electrosteric stealth Rivastigmine loaded liposomes for brain targeting: preparation, characterization, ex vivo, bio-distribution and in vivo pharmacokinetic studies
Sara Nageeb El-Helaly, Ahmed Abd Elbary, Mohamed A. Kassem & Mohamed A. El-Nabarawi
Pages: 692-700
Published online: 18 Apr 2017
AbstractforElectrosteric stealth Rivastigmine loaded liposomes for brain targeting: preparation, characterization, ex vivo, bio-distribution and in vivo pharmacokinetic studies | Full Text | References | PDF (520.9 KB) | Supplemental
  • 2807 Views
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Article
Transdermal iontophoresis patch with reverse electrodialysis
Joon Lee, Kilsung Kwon, Minyoung Kim, Joonhong Min, Nathaniel S. Hwang & Won-serk Kim
Pages: 701-706
Published online: 20 Apr 2017
AbstractforTransdermal iontophoresis patch with reverse electrodialysis | Full Text | References | PDF (1.3 MB)
  • 4142 Views
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Article
Design of a novel curcumin-soybean phosphatidylcholine complex-based targeted drug delivery systems
Jiajiang Xie, Yanxiu Li, Liang Song, Zhou Pan, Shefang Ye & Zhenqing Hou
Pages: 707-719
Published online: 24 Apr 2017
AbstractforDesign of a novel curcumin-soybean phosphatidylcholine complex-based targeted drug delivery systems | Full Text | References | PDF (3.2 MB)
  • 3388 Views
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Article
A novel matrix dispersion based on phospholipid complex for improving oral bioavailability of baicalein: preparation, in vitro and in vivo evaluations
Yang Zhou, Wujun Dong, Jun Ye, Huazhen Hao, Junzhuo Zhou, Renyun Wang & Yuling Liu
Pages: 720-728
Published online: 24 Apr 2017
AbstractforA novel matrix dispersion based on phospholipid complex for improving oral bioavailability of baicalein: preparation, in vitro and in vivo evaluations | Full Text | References | PDF (1 MB)
  • 2787 Views
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Article
N-Butyl-2-cyanoacrylate-based injectable and in situ-forming implants for efficient intratumoral chemotherapy
Yanpu Wu, Luming Wang, Kaili Zhang, Lixiao Zhou, Xiaobing Zhang, Xuecheng Jiang & Chenggang Zhu
Pages: 729-736
Published online: 25 Apr 2017
AbstractforN-Butyl-2-cyanoacrylate-based injectable and in situ-forming implants for efficient intratumoral chemotherapy | Full Text | References | PDF (1.7 MB) | Supplemental
  • 1561 Views
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Article
Effective intraperitoneal gene transfection system using nanobubbles and ultrasound irradiation
Koyo Nishimura, Shintaro Fumoto, Yuki Fuchigami, Masayori Hagimori, Kazuo Maruyama & Shigeru Kawakami
Pages: 737-744
Published online: 27 Apr 2017
AbstractforEffective intraperitoneal gene transfection system using nanobubbles and ultrasound irradiation | Full Text | References | PDF (1.5 MB) | Supplemental
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Letter
Preparation and testing of cefquinome-loaded poly lactic-co-glycolic acid microspheres for lung targeting
Shaoqi Qu, Li Zhao, Jiajia Zhu, Chunmei Wang, Cunchun Dai, Hui Guo & Zhihui Hao
Pages: 745-751
Published online: 28 Apr 2017
AbstractforPreparation and testing of cefquinome-loaded poly lactic-co-glycolic acid microspheres for lung targeting | Full Text | References | PDF (795.8 KB)
  • 2015 Views
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Article
Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer
Ziqing Duan, Cuitian Chen, Jing Qin, Qi Liu, Qi Wang, Xinchun Xu & Jianxin Wang
Pages: 752-764
Published online: 04 May 2017
AbstractforCell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer | Full Text | References | PDF (2.7 MB) | Supplemental
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Article
Characterization and antitumor efficacy of poly(L-lactid acid)-based etoposide-loaded implants
Li Gao, Chuanqi Xie, Yuzhi Du, Xiaodong Wang, Erkang Xuan, Xiuxiu Liu, Yang Zhao, Jianjian Xu & Lan Luo
Pages: 765-774
Published online: 05 May 2017
AbstractforCharacterization and antitumor efficacy of poly(L-lactid acid)-based etoposide-loaded implants | Full Text | References | PDF (2.3 MB)
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Review Article

Review
Photonic crystal materials and their application in biomedicine
Huadong Chen, Rong Lou, Yanxiao Chen, Lili Chen, Jingya Lu & Qianqian Dong
Pages: 775-780
Published online: 05 May 2017
AbstractforPhotonic crystal materials and their application in biomedicine | Full Text | References | PDF (621.7 KB)
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Research Articles

Article
Loratadine bioavailability via buccal transferosomal gel: formulation, statistical optimization, in vitro/in vivo characterization, and pharmacokinetics in human volunteers
Mohammed H. Elkomy, Shahira F. El Menshawe, Heba A. Abou-Taleb & Marwa H. Elkarmalawy
Pages: 781-791
Published online: 08 May 2017
AbstractforLoratadine bioavailability via buccal transferosomal gel: formulation, statistical optimization, in vitro/in vivo characterization, and pharmacokinetics in human volunteers | Full Text | References | PDF (896.3 KB) | Supplemental
  • 4553 Views
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Article
Cisplatin and paclitaxel co-delivered by folate-decorated lipid carriers for the treatment of head and neck cancer
Jiying Yang, Zengjuan Ju & Shufang Dong
Pages: 792-799
Published online: 11 May 2017
AbstractforCisplatin and paclitaxel co-delivered by folate-decorated lipid carriers for the treatment of head and neck cancer | Full Text | References | PDF (645.4 KB)
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Original Article

Article
Ceramide lipid-based nanosuspension for enhanced delivery of docetaxel with synergistic antitumor efficiency
Tianqi Wang, Lixia Feng, Shaomei Yang, Yongjun Liu & Na Zhang
Pages: 800-810
Published online: 13 May 2017
AbstractforCeramide lipid-based nanosuspension for enhanced delivery of docetaxel with synergistic antitumor efficiency | Full Text | References | PDF (2.8 MB)
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Research Articles

Article
Nanoparticle-based delivery enhances anti-inflammatory effect of low molecular weight heparin in experimental ulcerative colitis
Tawfek Yazeji, Brice Moulari, Arnaud Beduneau, Valentin Stein, Dirk Dietrich, Yann Pellequer & Alf Lamprecht
Pages: 811-817
Published online: 16 May 2017
AbstractforNanoparticle-based delivery enhances anti-inflammatory effect of low molecular weight heparin in experimental ulcerative colitis | Full Text | References | PDF (863.4 KB) | Supplemental
  • 2336 Views
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Article
Dexamethasone distribution characteristic following controllable continuous sub-tenon drug delivery in rabbit
Xuetao Huang, Manqiang Peng, Yezhen Yang, Yiqin Duan, Kuanshu Li, Shaogang Liu, Changhua Ye & Ding Lin
Pages: 818-824
Published online: 16 May 2017
AbstractforDexamethasone distribution characteristic following controllable continuous sub-tenon drug delivery in rabbit | Full Text | References | PDF (535.8 KB)
  • 1960 Views
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Article
PEG–lipid–PLGA hybrid nanoparticles loaded with berberine–phospholipid complex to facilitate the oral delivery efficiency
Fei Yu, Mingtao Ao, Xiao Zheng, Nini Li, Junjie Xia, Yang Li, Donghui Li, Zhenqing Hou, Zhongquan Qi & Xiao Dong Chen
Pages: 825-833
Published online: 16 May 2017
AbstractforPEG–lipid–PLGA hybrid nanoparticles loaded with berberine–phospholipid complex to facilitate the oral delivery efficiency | Full Text | References | PDF (1.7 MB)
  • 5406 Views
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Article
Preliminary study on fabrication, characterization and synergistic anti-lung cancer effects of self-assembled micelles of covalently conjugated celastrol–polyethylene glycol–ginsenoside Rh2
Peng Li, XiaoYue Zhou, Ding Qu, Mengfei Guo, Chenyi Fan, Tong Zhou & Yang Ling
Pages: 834-845
Published online: 22 May 2017
AbstractforPreliminary study on fabrication, characterization and synergistic anti-lung cancer effects of self-assembled micelles of covalently conjugated celastrol–polyethylene glycol–ginsenoside Rh2 | Full Text | References | PDF (2.3 MB) | Supplemental
  • 1843 Views
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Article
Etodolac transdermal cubosomes for the treatment of rheumatoid arthritis: ex vivo permeation and in vivo pharmacokinetic studies
Salwa Salah, Azza A. Mahmoud & Amany O. Kamel
Pages: 846-856
Published online: 23 May 2017
AbstractforEtodolac transdermal cubosomes for the treatment of rheumatoid arthritis: ex vivo permeation and in vivo pharmacokinetic studies | Full Text | References | PDF (1 MB)
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Article
Reversed lipid-based nanoparticles dispersed in oil for malignant tumor treatment via intratumoral injection
Liao Shen, Zhen Zhang, Tao Wang, Xi Yang, Ri Huang & Dongqin Quan
Pages: 857-866
Published online: 26 May 2017
AbstractforReversed lipid-based nanoparticles dispersed in oil for malignant tumor treatment via intratumoral injection | Full Text | References | PDF (3 MB)
  • 1569 Views
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Article
Temperature-sensitive heparin-modified poloxamer hydrogel with affinity to KGF facilitate the morphologic and functional recovery of the injured rat uterus
He-Lin Xu, Jie Xu, Si-Si Zhang, Qun-Yan Zhu, Bing-Hui Jin, De-Li ZhuGe, Bi-Xin Shen, Xue-Qing Wu, Jian Xiao & Ying-Zheng Zhao
Pages: 867-881
Published online: 02 Jun 2017
AbstractforTemperature-sensitive heparin-modified poloxamer hydrogel with affinity to KGF facilitate the morphologic and functional recovery of the injured rat uterus | Full Text | References | PDF (4 MB) | Supplemental
  • 3569 Views
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Article
Anti-CD123 antibody-modified niosomes for targeted delivery of daunorubicin against acute myeloid leukemia
Fu-rong Liu, Hui Jin, Yin Wang, Chen Chen, Ming Li, Sheng-jun Mao, Qiantao Wang & Hui Li
Pages: 882-890
Published online: 02 Jun 2017
AbstractforAnti-CD123 antibody-modified niosomes for targeted delivery of daunorubicin against acute myeloid leukemia | Full Text | References | PDF (1.2 MB)
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Review Article

Review
Toxicity of orally inhaled drug formulations at the alveolar barrier: parameters for initial biological screening
Eleonore Fröhlich
Pages: 891-905
Published online: 02 Jun 2017
AbstractforToxicity of orally inhaled drug formulations at the alveolar barrier: parameters for initial biological screening | Full Text | References | PDF (1.3 MB)
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Research Articles

Article
Characterization of transgene expression and pDNA distribution of the suctioned kidney in mice
Natsuko Oyama, Yuki Fuchigami, Shintaro Fumoto, Megumu Sato, Masayori Hagimori, Kazunori Shimizu & Shigeru Kawakami
Pages: 906-917
Published online: 06 Jun 2017
AbstractforCharacterization of transgene expression and pDNA distribution of the suctioned kidney in mice | Full Text | References | PDF (2.1 MB)
  • 1347 Views
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Article
Engineering of a novel optimized platform for sublingual delivery with novel characterization tools: in vitro evaluation and in vivo pharmacokinetics study in human
Nadia M. Morsi, Ghada A. Abdelbary, Ahmed H. Elshafeey & M. Abdallah Ahmed
Pages: 918-931
Published online: 09 Jun 2017
AbstractforEngineering of a novel optimized platform for sublingual delivery with novel characterization tools: in vitro evaluation and in vivo pharmacokinetics study in human | Full Text | References | PDF (1.5 MB) | Supplemental
  • 2887 Views
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Article
Atorvastatin-loaded nanostructured lipid carriers (NLCs): strategy to overcome oral delivery drawbacks
Mohammed Elmowafy, Hany M. Ibrahim, Mohammed A. Ahmed, Khaled Shalaby, Ayman Salama & Hossam Hefesha
Pages: 932-941
Published online: 15 Jun 2017
AbstractforAtorvastatin-loaded nanostructured lipid carriers (NLCs): strategy to overcome oral delivery drawbacks | Full Text | References | PDF (1.3 MB)
  • 5082 Views
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Article
Assessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity
Abbie Omolu, Maryse Bailly & Richard M. Day
Pages: 942-951
Published online: 15 Jun 2017
AbstractforAssessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity | Full Text | References | PDF (1.2 MB)
  • 2563 Views
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Article
Polyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice
Mingxing Wang, Bo Wu, Sapana N Shah, Peijuan Lu & Qilong Lu
Pages: 952-961
Published online: 20 Jun 2017
AbstractforPolyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice | Full Text | References | PDF (1.6 MB) | Supplemental
  • 1313 Views
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Article
Lipid-based nanosystem of edaravone: development, optimization, characterization and in vitro/in vivo evaluation
Ankit Parikh, Krishna Kathawala, Chun Chuan Tan, Sanjay Garg & Xin-Fu Zhou
Pages: 962-978
Published online: 21 Jun 2017
AbstractforLipid-based nanosystem of edaravone: development, optimization, characterization and in vitro/in vivo evaluation | Full Text | References | PDF (1.6 MB) | Supplemental
  • 3115 Views
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Article
Transdermal administration of melatonin coupled to cryopass laser treatment as noninvasive therapy for prostate cancer
Laura Terraneo, Paola Bianciardi, Eleonora Virgili, Elena Finati, Michele Samaja & Rita Paroni
Pages: 979-985
Published online: 23 Jun 2017
AbstractforTransdermal administration of melatonin coupled to cryopass laser treatment as noninvasive therapy for prostate cancer | Full Text | References | PDF (1.2 MB)
  • 1533 Views
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Article
Liposomes equipped with cell penetrating peptide BR2 enhances chemotherapeutic effects of cantharidin against hepatocellular carcinoma
Xue Zhang, Congcong Lin, Aiping Lu, Ge Lin, Huoji Chen, Qiang Liu, Zhijun Yang & Hongqi Zhang
Pages: 986-998
Published online: 23 Jun 2017
AbstractforLiposomes equipped with cell penetrating peptide BR2 enhances chemotherapeutic effects of cantharidin against hepatocellular carcinoma | Full Text | References | PDF (1.8 MB)
  • 3215 Views
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Article
Pullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine
Nina Henry, Johann Clouet, Audrey Fragale, Louise Griveau, Claire Chédeville, Joëlle Véziers, Pierre Weiss, Jean Le Bideau, Jérôme Guicheux & Catherine Le Visage
Pages: 999-1010
Published online: 23 Jun 2017
AbstractforPullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine | Full Text | References | PDF (1.3 MB)
  • 3238 Views
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Article
Comparison of pharmacokinetics and drug release in tissues after transarterial chemoembolization with doxorubicin using diverse lipiodol emulsions and CalliSpheres Beads in rabbit livers
Shuisheng Zhang, Can Huang, Zhengzheng Li, Yongjie Yang, Tingting Bao, Haibo Chen, Yinghua Zou & Li Song
Pages: 1011-1017
Published online: 29 Jun 2017
AbstractforComparison of pharmacokinetics and drug release in tissues after transarterial chemoembolization with doxorubicin using diverse lipiodol emulsions and CalliSpheres Beads in rabbit livers | Full Text | References | PDF (686.7 KB)
  • 3623 Views
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Article
A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
Kyeong Soo Kim, Eun Su Yang, Dong Shik Kim, Dong Wuk Kim, Hye Hyun Yoo, Chul Soon Yong, Yu Seok Youn, Kyung Taek Oh, Jun-Pil Jee, Jong Oh Kim, Sung Giu Jin & Han Gon Choi
Pages: 1018-1025
Published online: 04 Jul 2017
AbstractforA novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol | Full Text | References | PDF (1.1 MB) | Supplemental
  • 2686 Views
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Article
Fabrication, in-vitro characterization, and enhanced in-vivo evaluation of carbopol-based nanoemulsion gel of apigenin for UV-induced skin carcinoma
Manmohan S. Jangdey, Anshita Gupta & Swarnlata Saraf
Pages: 1026-1036
Published online: 07 Jul 2017
AbstractforFabrication, in-vitro characterization, and enhanced in-vivo evaluation of carbopol-based nanoemulsion gel of apigenin for UV-induced skin carcinoma | Full Text | References | PDF (1.1 MB)
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Review Article

Review
Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability
Qun-Lin Zhang, Bingmei M. Fu & Zhang-Jin Zhang
Pages: 1037-1044
Published online: 07 Jul 2017
AbstractforBorneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability | Full Text | References | PDF (938 KB)
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Research Articles

Article
Dual-modified liposome codelivery of doxorubicin and vincristine improve targeting and therapeutic efficacy of glioma
Yue Zhang, Meifang Zhai, Zhijiang Chen, Xiaoyang Han, Fanglin Yu, Zhiping Li, Xiangyang Xie, Cuiyan Han, Lian Yu, Yang Yang & Xingguo Mei
Pages: 1045-1055
Published online: 07 Jul 2017
AbstractforDual-modified liposome codelivery of doxorubicin and vincristine improve targeting and therapeutic efficacy of glioma | Full Text | References | PDF (1.6 MB)
  • 3850 Views
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Article
Formulation and in vitro/in vivo evaluation of chitosan-based film forming gel containing ketoprofen
Dong-Won Oh, Ji-Hyun Kang, Hyo-Jung Lee, Sang-Duk Han, Min-Hyung Kang, Yie-Hyuk Kwon, Joon-Ho Jun, Dong-Wook Kim, Yun-Seok Rhee, Ju-Young Kim, Eun-Seok Park & Chung-Woong Park
Pages: 1056-1066
Published online: 07 Jul 2017
AbstractforFormulation and in vitro/in vivo evaluation of chitosan-based film forming gel containing ketoprofen | Full Text | References | PDF (1.3 MB)
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Article
Atorvastatin-loaded micelles with bone-targeted ligand for the treatment of osteoporosis
Yonghui Xie, Xueying Tan, Jian Huang, Hongwei Huang, Ping Zou & Jingbo Hu
Pages: 1067-1076
Published online: 13 Jul 2017
AbstractforAtorvastatin-loaded micelles with bone-targeted ligand for the treatment of osteoporosis | Full Text | References | PDF (1.3 MB)
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Article
Agomelatine-based in situ gels for brain targeting via the nasal route: statistical optimization, in vitro, and in vivo evaluation
Ahmed M. Fatouh, Ahmed H. Elshafeey & Ahmed Abdelbary
Pages: 1077-1085
Published online: 26 Jul 2017
AbstractforAgomelatine-based in situ gels for brain targeting via the nasal route: statistical optimization, in vitro, and in vivo evaluation | Full Text | References | PDF (875.3 KB)
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Article
Biomimetic synthesis of proline-derivative templated mesoporous silica for increasing the brain distribution of diazepam and improving the pharmacodynamics of nimesulide
Heran Li, Jianxin Wang, Jialiang Cong, Chen Wei, Jing Li, Hongzhuo Liu, Sanming Li & Mingshi Yang
Pages: 1086-1098
Published online: 01 Aug 2017
AbstractforBiomimetic synthesis of proline-derivative templated mesoporous silica for increasing the brain distribution of diazepam and improving the pharmacodynamics of nimesulide | Full Text | References | PDF (1.7 MB)
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Article
Exploring the immunopotentiation of Chinese yam polysaccharide poly(lactic-co-glycolic acid) nanoparticles in an ovalbumin vaccine formulation in vivo
Li Luo, Tao Qin, Yifan Huang, Sisi Zheng, Ruonan Bo, Zhenguang Liu, Jie Xing, Yuanliang Hu, Jiaguo Liu & Deyun Wang
Pages: 1099-1111
Published online: 04 Aug 2017
AbstractforExploring the immunopotentiation of Chinese yam polysaccharide poly(lactic-co-glycolic acid) nanoparticles in an ovalbumin vaccine formulation in vivo | Full Text | References | PDF (2 MB)
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Article
Nanotechnology-based drug delivery of ropinirole for Parkinson’s disease
Emilia Barcia, Liudmila Boeva, Luis García-García, Karla Slowing, Ana Fernández-Carballido, Yaquelyn Casanova & Sofía Negro
Pages: 1112-1123
Published online: 06 Aug 2017
AbstractforNanotechnology-based drug delivery of ropinirole for Parkinson’s disease | Full Text | References | PDF (1.7 MB)
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Article
Co-delivery of docetaxel and bortezomib based on a targeting nanoplatform for enhancing cancer chemotherapy effects
Junpeng Nie, Wei Cheng, Yunmei Peng, Gan Liu, Yuhan Chen, Xusheng Wang, Chaoyu Liang, Wei Tao, Yinping Wei, Xiaowei Zeng & Lin Mei
Pages: 1124-1138
Published online: 08 Aug 2017
AbstractforCo-delivery of docetaxel and bortezomib based on a targeting nanoplatform for enhancing cancer chemotherapy effects | Full Text | References | PDF (2.4 MB) | Supplemental
  • 3026 Views
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Article
Novel composite drug delivery system as a novel radio sensitizer for the local treatment of cervical carcinoma
Shan Xu, Yu Ying Tang, Yan Xin Yu, Qin Yun, Jing Pin Yang, Heng Zhang, Qiuxia Peng, Xiaoyang Sun, Ling Lin Yang, ShaoZhi Fu & Jing Bo Wu
Pages: 1139-1147
Published online: 11 Aug 2017
AbstractforNovel composite drug delivery system as a novel radio sensitizer for the local treatment of cervical carcinoma | Full Text | References | PDF (1.3 MB)
  • 1371 Views
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Article
An injectable in situ gel with cubic and hexagonal nanostructures for local treatment of chronic periodontitis
Liling Mei, Xintian Huang, Yecheng Xie, Jintian Chen, Ying Huang, Bei Wang, Hui Wang, Xin Pan & Chuanbin Wu
Pages: 1148-1158
Published online: 17 Aug 2017
AbstractforAn injectable in situ gel with cubic and hexagonal nanostructures for local treatment of chronic periodontitis | Full Text | References | PDF (1.5 MB) | Supplemental
  • 2978 Views
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Article
Transdermal agomelatine microemulsion gel: pyramidal screening, statistical optimization and in vivo bioavailability
Mayada Said, Ibrahim Elsayed, Ahmed A. Aboelwafa & Ahmed H. Elshafeey
Pages: 1159-1169
Published online: 23 Aug 2017
AbstractforTransdermal agomelatine microemulsion gel: pyramidal screening, statistical optimization and in vivo bioavailability | Full Text | References | PDF (1.2 MB)
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Article
Redox-responsive PEGylated self-assembled prodrug-nanoparticles formed by single disulfide bond bridge periplocymarin-vitamin E conjugate for liver cancer chemotherapy
Huiyun Zhang, Wenqian Xu, Emmanuel Omari-Siaw, Yingkun Liu, Baoding Chen, Deyu Chen, Jiangnan Yu & Ximing Xu
Pages: 1170-1178
Published online: 24 Aug 2017
AbstractforRedox-responsive PEGylated self-assembled prodrug-nanoparticles formed by single disulfide bond bridge periplocymarin-vitamin E conjugate for liver cancer chemotherapy | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1901 Views
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Article
A multicomponent microemulsion using rational combination strategy improves lung cancer treatment through synergistic effects and deep tumor penetration
Ding Qu, Mengfei Guo, Yue Qin, Lixiang Wang, Bing Zong, Yunyan Chen & Yan Chen
Pages: 1179-1190
Published online: 25 Aug 2017
AbstractforA multicomponent microemulsion using rational combination strategy improves lung cancer treatment through synergistic effects and deep tumor penetration | Full Text | References | PDF (1.9 MB) | Supplemental
  • 1691 Views
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Article
Hierarchical pulmonary target nanoparticles via inhaled administration for anticancer drug delivery
Rui Chen, Liu Xu, Qin Fan, Man Li, Jingjing Wang, Li Wu, Weidong Li, Jinao Duan & Zhipeng Chen
Pages: 1191-1203
Published online: 28 Aug 2017
AbstractforHierarchical pulmonary target nanoparticles via inhaled administration for anticancer drug delivery | Full Text | References | PDF (1.6 MB) | Supplemental
  • 1858 Views
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Article
Novel reverse electrodialysis-driven iontophoretic system for topical and transdermal delivery of poorly permeable therapeutic agents
Ki-Taek Kim, Joon Lee, Min-Hwan Kim, Ju-Hwan Park, Jae-Young Lee, Joo-Hyun Song, Minwoong Jung, Myoung-Hoon Jang, Hyun-Jong Cho, In-Soo Yoon & Dae-Duk Kim
Pages: 1204-1215
Published online: 28 Aug 2017
AbstractforNovel reverse electrodialysis-driven iontophoretic system for topical and transdermal delivery of poorly permeable therapeutic agents | Full Text | References | PDF (1.6 MB) | Supplemental
  • 2461 Views
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Article
Novel CD123-aptamer-originated targeted drug trains for selectively delivering cytotoxic agent to tumor cells in acute myeloid leukemia theranostics
Haibin Wu, Meng Wang, Bo Dai, Yanmin Zhang, Ying Yang, Qiao Li, Mingyue Duan, Xi Zhang, Xiaomei Wang, Anmao Li & Liyu Zhang
Pages: 1216-1229
Published online: 28 Aug 2017
AbstractforNovel CD123-aptamer-originated targeted drug trains for selectively delivering cytotoxic agent to tumor cells in acute myeloid leukemia theranostics | Full Text | References | PDF (1.9 MB) | Supplemental
  • 2753 Views
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Article
Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy
Min Zhou, Xin Li, Yuanyuan Li, Qiu’e Yao, Yue Ming, Ziwei Li, Laichun Lu & Sanjun Shi
Pages: 1230-1242
Published online: 31 Aug 2017
AbstractforAscorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy | Full Text | References | PDF (1.9 MB)
  • 3277 Views
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Article
Acceptability of orodispersible films for delivery of medicines to infants and preschool children
Mine Orlu, Sejal R. Ranmal, Yucheng Sheng, Catherine Tuleu & Paul Seddon
Pages: 1243-1248
Published online: 31 Aug 2017
AbstractforAcceptability of orodispersible films for delivery of medicines to infants and preschool children | Full Text | References | PDF (948.8 KB)
  • 3131 Views
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Review Article

Review
Suppression of chronic inflammation with engineered nanomaterials delivering nuclear factor κB transcription factor decoy oligodeoxynucleotides
Leila Farahmand, Behrad Darvishi & Keivan Majidzadeh-A
Pages: 1249-1261
Published online: 05 Sep 2017
AbstractforSuppression of chronic inflammation with engineered nanomaterials delivering nuclear factor κB transcription factor decoy oligodeoxynucleotides | Full Text | References | PDF (1.2 MB)
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Research Articles

Article
Polyunsaturated fatty acid-based targeted nanotherapeutics to enhance the therapeutic efficacy of docetaxel
Thiruganesh Ramasamy, Pasupathi Sundaramoorthy, Hima Bindu Ruttala, Yongjoo Choi, Woo Hyun Shin, Jee-Heon Jeong, Sae Kwang Ku, Han-Gon Choi, Hwan Mook Kim, Chul Soon Yong & Jong Oh Kim
Pages: 1262-1272
Published online: 09 Sep 2017
AbstractforPolyunsaturated fatty acid-based targeted nanotherapeutics to enhance the therapeutic efficacy of docetaxel | Full Text | References | PDF (1.7 MB) | Supplemental
  • 1893 Views
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Article
Subretinal delivery of erythropoietin alleviates the N-methyl-N-nitrosourea-induced photoreceptor degeneration and visual functional impairments: an in vivo and ex vivo study
Ye Tao, Yue Wang, Zhao Ma, Liqiang Wang, Limin Qin, Lu Wang, Yi Fei Huang & Shizhong Zhang
Pages: 1273-1283
Published online: 09 Sep 2017
AbstractforSubretinal delivery of erythropoietin alleviates the N-methyl-N-nitrosourea-induced photoreceptor degeneration and visual functional impairments: an in vivo and ex vivo study | Full Text | References | PDF (1.4 MB)
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Article
Enhanced tumor targeting effects of a novel paclitaxel-loaded polymer: PEG–PCCL-modified magnetic iron oxide nanoparticles
Xinyi Li, Yuan Yang, Yiping Jia, Xuan Pu, Ting Yang, Yicheng Wang, Xuefei Ma, Qi Chen, Mengwen Sun, Dapeng Wei, Yu Kuang, Yang Li & Yu Liu
Pages: 1284-1294
Published online: 11 Sep 2017
AbstractforEnhanced tumor targeting effects of a novel paclitaxel-loaded polymer: PEG–PCCL-modified magnetic iron oxide nanoparticles | Full Text | References | PDF (1.6 MB)
  • 1319 Views
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Review Article

Book Review
Development of DNA tetrahedron-based drug delivery system
Yue Hu, Zhou Chen, He Zhang, Mingkai Li, Zheng Hou, Xiaoxing Luo & Xiaoyan Xue
Pages: 1295-1301
Published online: 11 Sep 2017
AbstractforDevelopment of DNA tetrahedron-based drug delivery system | Full Text | References | PDF (704.2 KB)
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Research Articles

Article
Promising galactose-decorated biodegradable poloxamer 188-PLGA diblock copolymer nanoparticles of resibufogenin for enhancing liver cancer therapy
Hao Dong, Li Tian, Meng Gao, Hong Xu, Chenghong Zhang, Li Lv, Jianbin Zhang, Changyuan Wang, Yan Tian & Xiaochi Ma
Pages: 1302-1316
Published online: 12 Sep 2017
AbstractforPromising galactose-decorated biodegradable poloxamer 188-PLGA diblock copolymer nanoparticles of resibufogenin for enhancing liver cancer therapy | Full Text | References | PDF (2.1 MB)
  • 2232 Views
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Article
Photopolymerization-based synthesis of iron oxide nanoparticle embedded PNIPAM nanogels for biomedical applications
Daniel J. Denmark, Robert H. Hyde, Charlotte Gladney, Manh-Huong Phan, Kirpal S. Bisht, Hariharan Srikanth, Pritish Mukherjee & Sarath Witanachchi
Pages: 1317-1324
Published online: 14 Sep 2017
AbstractforPhotopolymerization-based synthesis of iron oxide nanoparticle embedded PNIPAM nanogels for biomedical applications | Full Text | References | PDF (1.5 MB)
  • 2113 Views
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Article
Expansible thermal gelling foam aerosol for vaginal drug delivery
Liling Mei, Jintian Chen, Siqin Yu, Ying Huang, Yecheng Xie, Hui Wang, Xin Pan & Chuanbin Wu
Pages: 1325-1337
Published online: 18 Sep 2017
AbstractforExpansible thermal gelling foam aerosol for vaginal drug delivery | Full Text | References | PDF (1.9 MB) | Supplemental
  • 2573 Views
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Article
Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy
Longfa Kou, Qing Yao, Sathish Sivaprakasam, Qiuhua Luo, Yinghua Sun, Qiang Fu, Zhonggui He, Jin Sun & Vadivel Ganapathy
Pages: 1338-1349
Published online: 15 Sep 2017
AbstractforDual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy | Full Text | References | PDF (1.6 MB) | Supplemental
  • 3286 Views
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Article
Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice
Shiva Pathak, Shobha Regmi, Biki Gupta, Bijay K. Poudel, Tung Thanh Pham, Chul Soon Yong, Jong Oh Kim, Jae-Ryong Kim, Min Hui Park, Young Kyung Bae, Simmyung Yook, Cheol-Hee Ahn & Jee-Heon Jeong
Pages: 1350-1359
Published online: 15 Sep 2017
AbstractforSingle synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Investigation of the transport and absorption of Angelica sinensis polysaccharide through gastrointestinal tract both in vitro and in vivo
Kaiping Wang, Fang Cheng, Xianglin Pan, Tao Zhou, Xiqiu Liu, Ziming Zheng, Li Luo & Yu Zhang
Pages: 1360-1371
Published online: 18 Sep 2017
AbstractforInvestigation of the transport and absorption of Angelica sinensis polysaccharide through gastrointestinal tract both in vitro and in vivo | Full Text | References | PDF (1.5 MB) | Supplemental
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Article
Maximized nanodrug-loaded mesenchymal stem cells by a dual drug-loaded mode for the systemic treatment of metastatic lung cancer
Sen Yao, Xuqian Li, Jingxuan Liu, Yuqing Sun, Zhuanhe Wang & Yanyan Jiang
Pages: 1372-1383
Published online: 18 Sep 2017
AbstractforMaximized nanodrug-loaded mesenchymal stem cells by a dual drug-loaded mode for the systemic treatment of metastatic lung cancer | Full Text | References | PDF (1.9 MB) | Supplemental
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Article
Toward smart design of retinal drug carriers: a novel bovine retinal explant model to study the barrier role of the vitreoretinal interface
Karen Peynshaert, Joke Devoldere, Valérie Forster, Serge Picaud, Christian Vanhove, Stefaan C. De Smedt & Katrien Remaut
Pages: 1384-1394
Published online: 19 Sep 2017
AbstractforToward smart design of retinal drug carriers: a novel bovine retinal explant model to study the barrier role of the vitreoretinal interface | Full Text | References | PDF (13.3 MB)
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Article
Which inhaled corticosteroid and long-acting β-agonist combination is better in patients with moderate-to-severe asthma, a dry powder inhaler or a pressurized metered-dose inhaler?
Masato Muraki, Kyuya Gose, Soichiro Hanada, Hirochiyo Sawaguchi & Yuji Tohda
Pages: 1395-1400
Published online: 20 Sep 2017
AbstractforWhich inhaled corticosteroid and long-acting β-agonist combination is better in patients with moderate-to-severe asthma, a dry powder inhaler or a pressurized metered-dose inhaler? | Full Text | References | PDF (886.1 KB) | Supplemental
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Article
Glioma and microenvironment dual targeted nanocarrier for improved antiglioblastoma efficacy
Xiuzhen Wang, Qing Zhang, Lingyan Lv, Junjie Fu, Yan Jiang, Hongliang Xin & Qizheng Yao
Pages: 1401-1409
Published online: 21 Sep 2017
AbstractforGlioma and microenvironment dual targeted nanocarrier for improved antiglioblastoma efficacy | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
In vivo antitumor effect of endostatin-loaded chitosan nanoparticles combined with paclitaxel on Lewis lung carcinoma
Fang Xie, Rui-Lin Ding, Wen-Feng He, Zong-Jun-Lin Liu, Shao-Zhi Fu, Jing-Bo Wu, Ling-Lin Yang, Sheng Lin & Qing-Lian Wen
Pages: 1410-1418
Published online: 21 Sep 2017
AbstractforIn vivo antitumor effect of endostatin-loaded chitosan nanoparticles combined with paclitaxel on Lewis lung carcinoma | Full Text | References | PDF (1.3 MB)
  • 1782 Views
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Article
Enhancement of radiotherapy efficacy by pleiotropic liposomes encapsulated paclitaxel and perfluorotributylamine
Xing Jiang, Baoli Zhang, Zaigang Zhou, Lingtong Meng, Zhiling Sun, Yun Xu, Qiuping Xu, Ahu Yuan, Lixia Yu, Hanqing Qian, Jinhui Wu, Yiqiao Hu & Baorui Liu
Pages: 1419-1428
Published online: 22 Sep 2017
AbstractforEnhancement of radiotherapy efficacy by pleiotropic liposomes encapsulated paclitaxel and perfluorotributylamine | Full Text | References | PDF (1.7 MB) | Supplemental
  • 1914 Views
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Article
Brain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral, biochemical, neurochemical and histological alterations in mice
Monu Yadav, Milind Parle, Nidhi Sharma, Sameer Dhingra, Neha Raina & Deepak Kumar Jindal
Pages: 1429-1440
Published online: 25 Sep 2017
AbstractforBrain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral, biochemical, neurochemical and histological alterations in mice | Full Text | References | PDF (1.2 MB)
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Article
Near infrared light mediated photochemotherapy for efficiently treating deep orthotopic tumors guided by ultrasound imaging
Zuhua Wang, Shaoyan Xuan, Wenqi Qiu, Jiang Zhu, Xiaomeng Guo, Wei Li, Hanbo Zhang, Xiuliang Zhu, Yong-Zhong Du & Jian You
Pages: 1441-1452
Published online: 25 Sep 2017
AbstractforNear infrared light mediated photochemotherapy for efficiently treating deep orthotopic tumors guided by ultrasound imaging | Full Text | References | PDF (1.8 MB) | Supplemental
  • 1279 Views
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Article
A novel biosensor based on intestinal 3D organoids for detecting the function of BCRP
Lei Zhang, Junfang Zhao, Chenmeizi Liang, Mingyao Liu, Feng Xu & Xin Wang
Pages: 1453-1459
Published online: 26 Sep 2017
AbstractforA novel biosensor based on intestinal 3D organoids for detecting the function of BCRP | Full Text | References | PDF (1.1 MB)
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Article
Self-delivering prodrug-nanoassemblies fabricated by disulfide bond bridged oleate prodrug of docetaxel for breast cancer therapy
Shenwu Zhang, Jibin Guan, Mengchi Sun, Dong Zhang, Haotian Zhang, Bingjun Sun, Weiling Guo, Bin Lin, Yongjun Wang, Zhonggui He, Cong Luo & Jin Sun
Pages: 1460-1469
Published online: 26 Sep 2017
AbstractforSelf-delivering prodrug-nanoassemblies fabricated by disulfide bond bridged oleate prodrug of docetaxel for breast cancer therapy | Full Text | References | PDF (1.5 MB) | Supplemental
  • 2737 Views
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Article
Curcumin: a calixarene derivative micelle potentiates anti-breast cancer stem cells effects in xenografted, triple-negative breast cancer mouse models
Wei Chen, Lin Li, Xiaofen Zhang, Yuan Liang, Zhijun Pu, Lingfeng Wang & Jingxin Mo
Pages: 1470-1481
Published online: 28 Sep 2017
AbstractforCurcumin: a calixarene derivative micelle potentiates anti-breast cancer stem cells effects in xenografted, triple-negative breast cancer mouse models | Full Text | References | PDF (1.8 MB) | Supplemental
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Article
Targeted inhibition of human hematological cancers in vivo by doxorubicin encapsulated in smart lipoic acid-crosslinked hyaluronic acid nanoparticles
Yinan Zhong, Fenghua Meng, Chao Deng, Xinliang Mao & Zhiyuan Zhong
Pages: 1482-1490
Published online: 28 Sep 2017
AbstractforTargeted inhibition of human hematological cancers in vivo by doxorubicin encapsulated in smart lipoic acid-crosslinked hyaluronic acid nanoparticles | Full Text | References | PDF (1.6 MB) | Supplemental
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Article
Genkwanin nanosuspensions: a novel and potential antitumor drug in breast carcinoma therapy
Yijing Li, Jingyi Hong, Haowen Li, Xiaoyu Qi, Yifei Guo, Meihua Han & Xiangtao Wang
Pages: 1491-1500
Published online: 29 Sep 2017
AbstractforGenkwanin nanosuspensions: a novel and potential antitumor drug in breast carcinoma therapy | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1922 Views
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Article
In vitro and in vivo antitumor effect of gefitinib nanoparticles on human lung cancer
Xiao Ling Ni, Long Xia Chen, Heng Zhang, Bo Yang, Shan Xu, Min Wu, Jing Liu, Ling Lin Yang, Yue Chen, Shao Zhi Fu & Jing Bo Wu
Pages: 1501-1512
Published online: 29 Sep 2017
AbstractforIn vitro and in vivo antitumor effect of gefitinib nanoparticles on human lung cancer | Full Text | References | PDF (1.8 MB) | Supplemental
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Article
Insulin-loaded PLGA microspheres for glucose-responsive release
Jun-Zi Wu, Gareth R. Williams, He-Yu Li, Dong-Xiu Wang, Shu-De Li & Li-Min Zhu
Pages: 1513-1525
Published online: 04 Oct 2017
AbstractforInsulin-loaded PLGA microspheres for glucose-responsive release | Full Text | References | PDF (2.2 MB) | Supplemental
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Article
TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors
Xi Yang, Zhaojun Li, Qinjie Wu, Shouchun Chen, Cheng Yi & Changyang Gong
Pages: 1526-1536
Published online: 10 Oct 2017
AbstractforTRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors | Full Text | References | PDF (1.6 MB) | Supplemental
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Article
Self-assembling HA/PEI/dsRNA-p21 ternary complexes for CD44 mediated small active RNA delivery to colorectal cancer
Chen-Lin Feng, Yan-Xing Han, Hui-Hui Guo, Xiao-Lei Ma, Zhi-Qiang Wang, Lu-Lu Wang, Wen-Sheng Zheng & Jian-Dong Jiang
Pages: 1537-1548
Published online: 10 Oct 2017
AbstractforSelf-assembling HA/PEI/dsRNA-p21 ternary complexes for CD44 mediated small active RNA delivery to colorectal cancer | Full Text | References | PDF (4.6 MB)
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Article
GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways
Jiang Pi, Jinhuan Jiang, Huaihong Cai, Fen Yang, Hua Jin, Peihui Yang, Jiye Cai & Zheng W. Chen
Pages: 1549-1564
Published online: 11 Oct 2017
AbstractforGE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways | Full Text | References | PDF (3.1 MB) | Supplemental
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Article
A novel core-shell lipid nanoparticle for improving oral administration of water soluble chemotherapeutic agents: inhibited intestinal hydrolysis and enhanced lymphatic absorption
Tao Wang, Liao Shen, Zhen Zhang, Haiyan Li, Ri Huang, Yadan Zhang & Dongqin Quan
Pages: 1565-1573
Published online: 13 Oct 2017
AbstractforA novel core-shell lipid nanoparticle for improving oral administration of water soluble chemotherapeutic agents: inhibited intestinal hydrolysis and enhanced lymphatic absorption | Full Text | References | PDF (1.2 MB)
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Article
Quaternized chitosan nanoparticles loaded with the combined attenuated live vaccine against Newcastle disease and infectious bronchitis elicit immune response in chicken after intranasal administration
Kai Zhao, Shanshan Li, Wei Li, Lu Yu, Xutong Duan, Jinyu Han, Xiaohua Wang & Zheng Jin
Pages: 1574-1586
Published online: 13 Oct 2017
AbstractforQuaternized chitosan nanoparticles loaded with the combined attenuated live vaccine against Newcastle disease and infectious bronchitis elicit immune response in chicken after intranasal administration | Full Text | References | PDF (1.9 MB) | Supplemental
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Article
2-Hydroxyoleic acid-inserted liposomes as a multifunctional carrier of anticancer drugs
Eun-Ji Jang, Woo Rim Choi, Soo-Yeon Kim, Soon-Seok Hong, Inmoo Rhee, Sang-Jin Lee, Sung Weon Choi, Han-Gon Choi & Soo-Jeong Lim
Pages: 1587-1597
Published online: 13 Oct 2017
Abstractfor2-Hydroxyoleic acid-inserted liposomes as a multifunctional carrier of anticancer drugs | Full Text | References | PDF (1.2 MB)
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Article
Preparation and evaluation of Vinpocetine self-emulsifying pH gradient release pellets
Mengqi Liu, Shiming Zhang, Shuxia Cui, Fen Chen, Lianqun Jia, Shu Wang, Xiumei Gai, Pingfei Li, Feifei Yang, Weisan Pan & Xinggang Yang
Pages: 1598-1604
Published online: 18 Oct 2017
AbstractforPreparation and evaluation of Vinpocetine self-emulsifying pH gradient release pellets | Full Text | References | PDF (765.3 KB)
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Article
N-acetyl-L-cysteine functionalized nanostructured lipid carrier for improving oral bioavailability of curcumin: preparation, in vitro and in vivo evaluations
Cihui Tian, Sajid Asghar, Yifan Wu, Daddy Kambere Amerigos, Zhipeng Chen, Mei Zhang, Lining Yin, Lin Huang, Qineng Ping & Yanyu Xiao
Pages: 1605-1616
Published online: 24 Oct 2017
AbstractforN-acetyl-L-cysteine functionalized nanostructured lipid carrier for improving oral bioavailability of curcumin: preparation, in vitro and in vivo evaluations | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy
Lan Li, Jingyu Ni, Min Li, Jingrui Chen, Lifeng Han, Yan Zhu, Deling Kong, Jingyuan Mao, Yi Wang, Boli Zhang, Meifeng Zhu, Xiumei Gao & Guanwei Fan
Pages: 1617-1630
Published online: 24 Oct 2017
AbstractforGinsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy | Full Text | References | PDF (2.2 MB) | Supplemental
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Article
Critical physicochemical and biological attributes of nanoemulsions for pulmonary delivery of rifampicin by nebulization technique in tuberculosis treatment
Kifayatullah Shah, Lai Wah Chan & Tin Wui Wong
Pages: 1631-1647
Published online: 24 Oct 2017
AbstractforCritical physicochemical and biological attributes of nanoemulsions for pulmonary delivery of rifampicin by nebulization technique in tuberculosis treatment | Full Text | References | PDF (1.7 MB)
  • 3089 Views
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Article
Immunotherapeutic effect of BCG-polysaccharide nucleic acid powder on Mycobacterium tuberculosis-infected mice using microneedle patches
Qinying Yan, Houming Liu, Zhigang Cheng, Yun Xue, Zhide Cheng, Xuyong Dai, Wanshui Shan & Fan Chen
Pages: 1648-1653
Published online: 25 Oct 2017
AbstractforImmunotherapeutic effect of BCG-polysaccharide nucleic acid powder on Mycobacterium tuberculosis-infected mice using microneedle patches | Full Text | References | PDF (900.3 KB) | Supplemental
  • 2132 Views
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Article
The role of osmolarity adjusting agents in the regulation of encapsulated cell behavior to provide a safer and more predictable delivery of therapeutics
Ainhoa Gonzalez-Pujana, Aitor Rementeria, Francisco Javier Blanco, Manoli Igartua, Jose Luis Pedraz, Edorta Santos-Vizcaino & Rosa Maria Hernandez
Pages: 1654-1666
Published online: 27 Oct 2017
AbstractforThe role of osmolarity adjusting agents in the regulation of encapsulated cell behavior to provide a safer and more predictable delivery of therapeutics | Full Text | References | PDF (2.4 MB) | Supplemental
  • 3334 Views
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Article
Characterization of brusatol self-microemulsifying drug delivery system and its therapeutic effect against dextran sodium sulfate-induced ulcerative colitis in mice
Jiangtao Zhou, Lihua Tan, Jianhui Xie, Zhengquan Lai, Yanfeng Huang, Chang Qu, Dandan Luo, Zhixiu Lin, Ping Huang, Ziren Su & Youliang Xie
Pages: 1667-1679
Published online: 27 Oct 2017
AbstractforCharacterization of brusatol self-microemulsifying drug delivery system and its therapeutic effect against dextran sodium sulfate-induced ulcerative colitis in mice | Full Text | References | PDF (1.7 MB)
  • 2955 Views
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Article
Synergistic dual-modified liposome improves targeting and therapeutic efficacy of bone metastasis from breast cancer
Xianzhu Ke, Wen Lin, Xiaokang Li, Hailiang Wang, Xin Xiao & Zheng Guo
Pages: 1680-1689
Published online: 02 Nov 2017
AbstractforSynergistic dual-modified liposome improves targeting and therapeutic efficacy of bone metastasis from breast cancer | Full Text | References | PDF (1.4 MB) | Supplemental
  • 2472 Views
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Article
Hydrophobic binding peptide-conjugated hybrid lipid-mesoporous silica nanoparticles for effective chemo-photothermal therapy of pancreatic cancer
Raj Kumar Thapa, Hanh Thuy Nguyen, Milan Gautam, Aarajana Shrestha, Eung Seok Lee, Sae Kwang Ku, Han-Gon Choi, Chul Soon Yong & Jong Oh Kim
Pages: 1690-1702
Published online: 03 Nov 2017
AbstractforHydrophobic binding peptide-conjugated hybrid lipid-mesoporous silica nanoparticles for effective chemo-photothermal therapy of pancreatic cancer | Full Text | References | PDF (2.4 MB) | Supplemental
  • 2471 Views
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Article
A novel lipid prodrug strategy for sustained delivery of hexadecyloxypropyl 9-[2-(phosphonomethoxy)ethyl]guanine (HDP-PMEG) on unwanted ocular proliferation
Mei Chen, Jiangping Hou, Guilin Tan, Peng Xie, William R. Freeman, James R. Beadle, Karl Y. Hostetler & Lingyun Cheng
Pages: 1703-1712
Published online: 08 Nov 2017
AbstractforA novel lipid prodrug strategy for sustained delivery of hexadecyloxypropyl 9-[2-(phosphonomethoxy)ethyl]guanine (HDP-PMEG) on unwanted ocular proliferation | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1109 Views
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Article
Preparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique
Weiwei Wu, Yuangang Zu, Li Wang, Lingling Wang, Huimei Wang, Yuanyuan Li, Mingfang Wu, Xiuhua Zhao & Yujie Fu
Pages: 1713-1720
Published online: 08 Nov 2017
AbstractforPreparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique | Full Text | References | PDF (922.6 KB) | Supplemental
  • 2796 Views
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Article
Carbonate apatite nanoparticles carry siRNA(s) targeting growth factor receptor genes egfr1 and erbb2 to regress mouse breast tumor
Snigdha Tiash, Nur Izyani Binti Kamaruzman & Ezharul Hoque Chowdhury
Pages: 1721-1730
Published online: 09 Nov 2017
AbstractforCarbonate apatite nanoparticles carry siRNA(s) targeting growth factor receptor genes egfr1 and erbb2 to regress mouse breast tumor | Full Text | References | PDF (1.1 MB) | Supplemental
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Article
Sustained-release solid dispersion of pelubiprofen using the blended mixture of aminoclay and pH independent polymers: preparation and in vitro/in vivo characterization
Yeo-Song Lee, Jae Guen Song, Sang Hoon Lee & Hyo-Kyung Han
Pages: 1731-1739
Published online: 10 Nov 2017
AbstractforSustained-release solid dispersion of pelubiprofen using the blended mixture of aminoclay and pH independent polymers: preparation and in vitro/in vivo characterization | Full Text | References | PDF (1.2 MB) | Supplemental
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Article
Development of magnetic anionic liposome/atelocollagen complexes for efficient magnetic drug targeting
Yusuke Kono, Taketo Nakai, Hitomi Taguchi & Takuya Fujita
Pages: 1740-1749
Published online: 15 Nov 2017
AbstractforDevelopment of magnetic anionic liposome/atelocollagen complexes for efficient magnetic drug targeting | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1577 Views
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Article
SS-31 peptide enables mitochondrial targeting drug delivery: a promising therapeutic alteration to prevent hair cell damage from aminoglycosides
Xiao Kuang, Shuang Zhou, Weiling Guo, Zhenjie Wang, Yanhui Sun & Hongzhuo Liu
Pages: 1750-1761
Published online: 07 Dec 2017
AbstractforSS-31 peptide enables mitochondrial targeting drug delivery: a promising therapeutic alteration to prevent hair cell damage from aminoglycosides | Full Text | References | PDF (1.5 MB) | Supplemental
  • 3185 Views
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Article
Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation
Amr Mostafa El Sharawy, Marwa Hassan Shukr & Ahmed Hassen Elshafeey
Pages: 1762-1769
Published online: 24 Nov 2017
AbstractforFormulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation | Full Text | References | PDF (823.4 KB)
  • 3190 Views
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Article
Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury
Nan Li, Dong Weng, Shan-Mei Wang, Yuan Zhang, Shan-Shan Chen, Zhao-Fang Yin, Jiali Zhai, Judy Scoble, Charlotte C. Williams, Tao Chen, Hui Qiu, Qin Wu, Meng-Meng Zhao, Li-Qin Lu, Xavier Mulet & Hui-Ping Li
Pages: 1770-1781
Published online: 21 Nov 2017
AbstractforSurfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury | Full Text | References | PDF (1.7 MB)
  • 2960 Views
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Article
Reduction-responsive PEtOz-SS-PCL micelle with tailored size to overcome blood–brain barrier and enhance doxorubicin antiglioma effect
Yuling Li, Li Baiyang, Bu Leran, Wang Zhen, Xie Yandong, Du Baixiang, Zhu Dandan, Zhu Yufu, Liang Jun, Yu Rutong & Liu Hongmei
Pages: 1782-1790
Published online: 24 Nov 2017
AbstractforReduction-responsive PEtOz-SS-PCL micelle with tailored size to overcome blood–brain barrier and enhance doxorubicin antiglioma effect | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1375 Views
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Article
Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer
Shengpeng Wang, Min Shao, Zhangfeng Zhong, Anqi Wang, Jiliang Cao, Yucong Lu, Yitao Wang & Jinming Zhang
Pages: 1791-1800
Published online: 24 Nov 2017
AbstractforCo-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer | Full Text | References | PDF (1.6 MB)
  • 2688 Views
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Article
Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab-paclitaxel
Anne Steins, Eva A. Ebbing, Marcel C. M. Pistorius, Cynthia Waasdorp, Kausilia K. Krishnadath, Jan Paul Medema, Johanna W. Wilmink, Ron A. A. Mathôt, Maarten F. Bijlsma & Hanneke W. M. van Laarhoven
Pages: 1801-1810
Published online: 24 Nov 2017
AbstractforSystemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab-paclitaxel | Full Text | References | PDF (1.5 MB) | Supplemental
  • 1607 Views
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Article
A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231
Xiufeng Liu, Xintong Liu, Suwen Sunchen, Meixia Liu, Chen Shen, Juanjuan Wu, Wanli Zhao, Boyang Yu & Jihua Liu
Pages: 1811-1817
Published online: 24 Nov 2017
AbstractforA novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231 | Full Text | References | PDF (925.8 KB) | Supplemental
  • 1344 Views
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Article
PDGFRβ-specific affibody-directed delivery of a photosensitizer, IR700, is efficient for vascular-targeted photodynamic therapy of colorectal cancer
Qiuxiao Shi, Ze Tao, Hao Yang, Qing Fan, Danfeng Wei, Lin Wan & Xiaofeng Lu
Pages: 1818-1830
Published online: 28 Nov 2017
AbstractforPDGFRβ-specific affibody-directed delivery of a photosensitizer, IR700, is efficient for vascular-targeted photodynamic therapy of colorectal cancer | Full Text | References | PDF (2.3 MB) | Supplemental
  • 2421 Views
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Review Article

Review
Recent developments in d-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy
Songwei Tan, Chenming Zou, Wei Zhang, Mingxing Yin, Xueqin Gao & Qing Tang
Pages: 1831-1842
Published online: 28 Nov 2017
AbstractforRecent developments in d-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy | Full Text | References | PDF (1.6 MB) | Supplemental
  • 5612 Views
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Research Article

Article
VEGF-mediated tight junctions pathological fenestration enhances doxorubicin-loaded glycolipid-like nanoparticles traversing BBB for glioblastoma-targeting therapy
Lijuan Wen, Yanan Tan, Suhuan Dai, Yun Zhu, Tingting Meng, Xiqin Yang, Yupeng Liu, Xuan Liu, Hong Yuan & Fuqiang Hu
Pages: 1843-1855
Published online: 28 Nov 2017
AbstractforVEGF-mediated tight junctions pathological fenestration enhances doxorubicin-loaded glycolipid-like nanoparticles traversing BBB for glioblastoma-targeting therapy | Full Text | References | PDF (2.1 MB) | Supplemental
  • 2827 Views
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Original Article

Retraction
RETRACTED ARTICLE: Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury
Pages: 1856-1867
Published online: 30 Nov 2017
AbstractforRETRACTED ARTICLE: Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury | PDF (2.2 MB) | Supplemental
  • 2016 Views
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Research Articles

Article
Nanoemulsion-based delivery system for enhanced oral bioavailability and Caco-2 cell monolayers permeability of berberine hydrochloride
Yong-Jiang Li, Xiong-Bin Hu, Xiu-Ling Lu, De-Hua Liao, Tian-Tian Tang, Jun-Yong Wu & Da-Xiong Xiang
Pages: 1868-1873
Published online: 01 Dec 2017
AbstractforNanoemulsion-based delivery system for enhanced oral bioavailability and Caco-2 cell monolayers permeability of berberine hydrochloride | Full Text | References | PDF (884.4 KB) | Supplemental
  • 3773 Views
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Article
Stealth lipid polymer hybrid nanoparticles loaded with rutin for effective brain delivery – comparative study with the gold standard (Tween 80): optimization, characterization and biodistribution
Rania A. H. Ishak, Nada M. Mostafa & Amany O. Kamel
Pages: 1874-1890
Published online: 01 Dec 2017
AbstractforStealth lipid polymer hybrid nanoparticles loaded with rutin for effective brain delivery – comparative study with the gold standard (Tween 80): optimization, characterization and biodistribution | Full Text | References | PDF (2 MB) | Supplemental
  • 3809 Views
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Article
Optimization on biodistribution and antitumor activity of tripterine using polymeric nanoparticles through RES saturation
Juntao Yin, Peiqing Wang, Yuyun Yin, Yantao Hou & Xiaoyong Song
Pages: 1891-1897
Published online: 01 Dec 2017
AbstractforOptimization on biodistribution and antitumor activity of tripterine using polymeric nanoparticles through RES saturation | Full Text | References | PDF (959.6 KB) | Supplemental
  • 1102 Views
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Review Articles

Review
Drug delivery vectors based on filamentous bacteriophages and phage-mimetic nanoparticles
Zhigang Ju & Wei Sun
Pages: 1898-1908
Published online: 01 Dec 2017
AbstractforDrug delivery vectors based on filamentous bacteriophages and phage-mimetic nanoparticles | Full Text | References | PDF (1 MB)
  • 6346 Views
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Review
Co-delivery nanoparticles of anti-cancer drugs for improving chemotherapy efficacy
Shan-Shan Qi, Jia-Hui Sun, Hao-Han Yu & Shu-Qin Yu
Pages: 1909-1926
Published online: 01 Dec 2017
AbstractforCo-delivery nanoparticles of anti-cancer drugs for improving chemotherapy efficacy | Full Text | References | PDF (1.6 MB)
  • 8713 Views
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Corrigendum

Correction
Correction to: Zhang etal., Comparison of pharmacokinetics and drug release in tissues after transarterial chemoembolization with doxorubicin using diverse lipiodol emulsions and CalliSpheres Beads in rabbit livers
Page: 1927
Published online: 10 Jul 2017
CitationforCorrection to: Zhang etal., Comparison of pharmacokinetics and drug release in tissues after transarterial chemoembolization with doxorubicin using diverse lipiodol emulsions and CalliSpheres Beads in rabbit livers | Full Text | PDF (142.1 KB)
  • 944 Views
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Correction
Correction to: Mei et al., An injectable in situ gel with cubic, hexagonal nanostructures for local treatment of chronic periodontitis
Page: 1928
Published online: 28 Sep 2017
CitationforCorrection to: Mei et al., An injectable in situ gel with cubic, hexagonal nanostructures for local treatment of chronic periodontitis | Full Text | PDF (152 KB)
  • 522 Views
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Correction
Correction to: Dong et al., Promising galactose-decorated biodegradable poloxamer 188-PLGA diblock copolymer nanoparticles of resibufogenin for enhancing liver cancer therapy
Page: 1929
Published online: 25 Oct 2017
CitationforCorrection to: Dong et al., Promising galactose-decorated biodegradable poloxamer 188-PLGA diblock copolymer nanoparticles of resibufogenin for enhancing liver cancer therapy | Full Text | PDF (151.7 KB)
  • 603 Views
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Correction
Correction to: Tan et al., Recent developments in D-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy
Page: 1930
Published online: 04 Dec 2017
CitationforCorrection to: Tan et al., Recent developments in D-α-tocopheryl polyethylene glycol-succinate-based nanomedicine for cancer therapy | Full Text | PDF (151.4 KB)
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