Expert Opinion on Drug Discovery, Volume 2, Issue 1 (2007)

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Expert Opinion on Drug Discovery, Volume 2, Issue 1 (2007)

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Reviews

Article
Malignant glioma drug discovery – targeting protein kinases
Sith Sathornsumetee, Kaitlyn A Vredenburgh, Kathryn P Lattimore & Jeremy N Rich
Pages: 1-17
Published online: 16 Jan 2007
AbstractforMalignant glioma drug discovery – targeting protein kinases | Full Text | References | PDF (564.8 KB)
  • 68 Views
  • 18 CrossRef citations
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Article
Using databases and data mining in vaccinology
Matthew N Davies, Pingping Guan, Martin J Blythe, Jesper Salomon, Christopher P Toseland, Channa Hattotuwagama, Valerie Walshe, Irini A Doytchinova & Darren R Flower
Pages: 19-35
Published online: 16 Jan 2007
AbstractforUsing databases and data mining in vaccinology | Full Text | References | PDF (424.8 KB)
  • 76 Views
  • 8 CrossRef citations
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Article
Combining ligand-based and structure-based drug design in the virtual screening arena
Stefano Moro, Magdalena Bacilieri & Francesca Deflorian
Pages: 37-49
Published online: 16 Jan 2007
AbstractforCombining ligand-based and structure-based drug design in the virtual screening arena | Full Text | References | PDF (191.6 KB)
  • 182 Views
  • 18 CrossRef citations
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Article
The importance of plasma protein binding in drug discovery
George L Trainor
Pages: 51-64
Published online: 16 Jan 2007
AbstractforThe importance of plasma protein binding in drug discovery | Full Text | References | PDF (158.1 KB)
  • 2799 Views
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Article
Optical molecular imaging in drug discovery and clinical development
Bohumil Bednar, Guo-Jun Zhang, David L Williams Jr, Richard Hargreaves & Cyrille Sur
Pages: 65-85
Published online: 16 Jan 2007
AbstractforOptical molecular imaging in drug discovery and clinical development | Full Text | References | PDF (537.6 KB)
  • 113 Views
  • 15 CrossRef citations
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Article
Indolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3D QSAR studies
Rino Ragno, Antonia Coluccia, Giuseppe La Regina & Romano Silvestri
Pages: 87-114
Published online: 16 Jan 2007
AbstractforIndolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3D QSAR studies | Full Text | References | PDF (594.7 KB)
  • 43 Views
  • 5 CrossRef citations
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Drug Discovery Case History

Article
Ceftobiprole – a case study
Malcolm GP Page
Pages: 115-129
Published online: 16 Jan 2007
AbstractforCeftobiprole – a case study | Full Text | References | PDF (188.6 KB)
  • 93 Views
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Technology Evaluation

Article
Molecular field technology applied to virtual screening and finding the bioactive conformation
Tim Cheeseright, Mark Mackey PhD, Sally Rose PhD & Andy Vinter PhD
Pages: 131-144
Published online: 16 Jan 2007
AbstractforMolecular field technology applied to virtual screening and finding the bioactive conformation | Full Text | References | PDF (566.6 KB)
  • 147 Views
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Article
New solid-state chemistry technologies to bring better drugs to market: knowledge-based decision making
Aeri Park, Leonard J Chyall, Jeanette Dunlap, Christine Schertz, David Jonaitis, Barbara C Stahly, Simon Bates, Rex Shipplett & Scott Childs
Pages: 145-154
Published online: 16 Jan 2007
AbstractforNew solid-state chemistry technologies to bring better drugs to market: knowledge-based decision making | Full Text | References | PDF (299.7 KB)
  • 144 Views
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