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Volume 9, Issue 8

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 9, Issue 8 (2014)

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Expert Opinion on Drug Discovery, Volume 9, Issue 8 (2014)

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Vol 19, 2024 Vol 18, 2023 Vol 17, 2022 Vol 16, 2021 Vol 15, 2020 Vol 14, 2019 Vol 13, 2018 Vol 12, 2017 Vol 11, 2016 Vol 10, 2015 Volume 9, 2014 Vol 8, 2013 Vol 7, 2012 Vol 6, 2011 Vol 5, 2010 Vol 4, 2009 Vol 3, 2008 Vol 2, 2007 Vol 1, 2006

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Editorial

The future of drug discovery: enabling technologies for enhancing lead characterization and profiling therapeutic potential

David R Janero

Pages: 847-858

Published online: 26 Jun 2014

AbstractforThe future of drug discovery: enabling technologies for enhancing lead characterization and profiling therapeutic potential | Full Text | References | PDF (499.4 KB)

2178 Views
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Reviews

Review Article

Discovery methodology for the development of direct factor VIIa inhibitors

Brian L Henry MD PhD & Umesh R Desai PhD

Pages: 859-872

Published online: 31 May 2014

AbstractforDiscovery methodology for the development of direct factor VIIa inhibitors | Full Text | References | PDF (635.7 KB)

135 Views
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Review Article

In vitro and in vivo approaches to characterize transporter-mediated disposition in drug discovery

Bo Feng PhD, Manthena V Varma PhD, Chester Costales PhD, Hui Zhang PhD & Larry Tremaine PhD

Pages: 873-890

Published online: 24 May 2014

AbstractforIn vitro and in vivo approaches to characterize transporter-mediated disposition in drug discovery | Full Text | References | PDF (503.7 KB)

1111 Views
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Review Article

Design and development of antivirals and intervention strategies against human herpesviruses using high-throughput approach

Julia Hornig & Alistair McGregor

Pages: 891-915

Published online: 08 Jul 2014

AbstractforDesign and development of antivirals and intervention strategies against human herpesviruses using high-throughput approach | Full Text | References | PDF (817.7 KB)

325 Views
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Review Article

Epigenetic approaches for bipolar disorder drug discovery

Jacob Peedicayil

Pages: 917-930

Published online: 29 May 2014

AbstractforEpigenetic approaches for bipolar disorder drug discovery | Full Text | References | PDF (415.6 KB)

291 Views
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Review Article

Pharmacophore modeling technique applied for the discovery of proteasome inhibitors

Chiara Pautasso, Rossella Troia, Mariella Genuardi & Antonio Palumbo

Pages: 931-943

Published online: 30 May 2014

AbstractforPharmacophore modeling technique applied for the discovery of proteasome inhibitors | Full Text | References | PDF (1,018 KB)

224 Views
6 CrossRef citations
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Review Article

Bone metabolism and adipokines: are there perspectives for bone diseases drug discovery?

Morena Scotece, Javier Conde, Vanessa Abella, Verónica López, Jesús Pino, Francisca Lago, Juan J Gómez-Reino & Oreste Gualillo

Pages: 945-957

Published online: 24 May 2014

AbstractforBone metabolism and adipokines: are there perspectives for bone diseases drug discovery? | Full Text | References | PDF (441.3 KB)

216 Views
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Review Article

Novel targeted therapies for the treatment of penile cancer

Gautum Agarwal MD, Shilpa Gupta MD & Philippe E Spiess (Associate member) MD MS FACS

Pages: 959-968

Published online: 04 Jun 2014

AbstractforNovel targeted therapies for the treatment of penile cancer | Full Text | References | PDF (283.4 KB)

200 Views
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Drug Discovery Case History

Article

Discovery and preclinical development of vismodegib

Stephen E Gould PhD, Jennifer A Low MD PhD, James C Marsters Jr PhD, Kirk Robarge PhD, Lee L Rubin PhD, Frederic J de Sauvage PhD, Daniel P Sutherlin PhD, Harvey Wong PhD & Robert L Yauch PhD

Pages: 969-984

Published online: 23 May 2014

AbstractforDiscovery and preclinical development of vismodegib | Full Text | References | PDF (1.3 MB)

1267 Views
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Expert Opinion on Drug Discovery (Vol.9, Iss.8, 2014)

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