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Volume 18, Issue 11

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 18, Issue 11 (2009)

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Expert Opinion on Investigational Drugs, Volume 18, Issue 11 (2009)

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Vol 33, 2024 Vol 32, 2023 Vol 31, 2022 Vol 30, 2021 Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Volume 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 Vol 12, 2003 Vol 11, 2002 Vol 10, 2001 Vol 9, 2000 Vol 8, 1999 Vol 7, 1998 Vol 6, 1997 Vol 5, 1996 Vol 4, 1995 Vol 3, 1994

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Discontinued Drugs Perspective

Article

Discontinued drugs in 2008: oncology drugs

Robert Williams

Pages: 1581-1594

Published online: 11 Aug 2009

AbstractforDiscontinued drugs in 2008: oncology drugs | Full Text | References | PDF (378 KB)

305 Views
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Original Research

Article

Oxaliplatin induces apoptosis in hepatocellular carcinoma cells and inhibits tumor growth

Zheng Wang, Jian Zhou, Jia Fan MD PHD, Shuang-Jian Qiu, Yao Yu, Xiao-Wu Huang, Jian Sun, Chang-Jun Tan & Zhi Dai

Pages: 1595-1604

Published online: 28 Sep 2009

AbstractforOxaliplatin induces apoptosis in hepatocellular carcinoma cells and inhibits tumor growth | Full Text | References | PDF (2.4 MB)

353 Views
17 CrossRef citations
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Reviews

Article

Targeting of HDAC8 and investigational inhibitors in neuroblastoma

Ina Oehme, Hedwig E Deubzer, Marco Lodrini, Till Milde & Olaf Witt

Pages: 1605-1617

Published online: 28 Sep 2009

AbstractforTargeting of HDAC8 and investigational inhibitors in neuroblastoma | Full Text | References | PDF (1.2 MB)

773 Views
61 CrossRef citations
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Article

Novel investigational adenosine A_2A receptor antagonists for Parkinson's disease

Annalisa Pinna

Pages: 1619-1631

Published online: 04 Nov 2009

AbstractforNovel investigational adenosine A_2A receptor antagonists for Parkinson's disease | Full Text | References | PDF (397.6 KB)

546 Views
69 CrossRef citations
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Article

Investigating the role of PDGF as a potential drug therapy in bone formation and fracture healing

Simon Graham MBChB, Andreas Leonidou MBChB MRCS, Marie Lester MBChB, Manolis Heliotis MSc FDS FRCS, Athanasios Mantalaris PhD & Eleftherios Tsiridis MD MSc PhD FRCS

Pages: 1633-1654

Published online: 13 Sep 2009

AbstractforInvestigating the role of PDGF as a potential drug therapy in bone formation and fracture healing | Full Text | References | PDF (419.4 KB)

565 Views
85 CrossRef citations
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Article

Monotherapy versus combination therapy for the treatment of chronic hepatitis B

Ivana Carey & Phillip M Harrison

Pages: 1655-1666

Published online: 23 Oct 2009

AbstractforMonotherapy versus combination therapy for the treatment of chronic hepatitis B | Full Text | References | PDF (311.9 KB)

223 Views
29 CrossRef citations
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Article

Antivascular agents for non-small-cell lung cancer: current status and future directions

Eitan Amir, Laszlo Mandoky, Fiona Blackhall, Nick Thatcher, Walter Klepetko, Hendrik Jan Ankersmit, Mir Ali Reza Hoda, Gyula Ostoros, Magdolna Dank & Balazs Dome MD PhD

Pages: 1667-1686

Published online: 30 Oct 2009

AbstractforAntivascular agents for non-small-cell lung cancer: current status and future directions | Full Text | References | PDF (383.1 KB)

115 Views
7 CrossRef citations
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Article

Will treatment of rheumatoid arthritis with an IL-6R inhibitor help facilitate the ‘age of remission’?

Robert J Moots PhD, Andrew JK Östör MBBS & John D Isaacs PhD

Pages: 1687-1699

Published online: 28 Aug 2009

AbstractforWill treatment of rheumatoid arthritis with an IL-6R inhibitor help facilitate the ‘age of remission’? | Full Text | References | PDF (413.7 KB)

149 Views
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Article

Novel VEGF signalling inhibitors: how helpful are biomarkers in their early development?

Joanna Wood, Edwina Scott & Anne L Thomas

Pages: 1701-1714

Published online: 30 Oct 2009

AbstractforNovel VEGF signalling inhibitors: how helpful are biomarkers in their early development? | Full Text | References | PDF (322.2 KB)

81 Views
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Drug Evaluations

Article

Lurasidone: a new drug in development for schizophrenia

Jonathan M Meyer MD, Antony D Loebel MD & Edward Schweizer MD

Pages: 1715-1726

Published online: 28 Sep 2009

AbstractforLurasidone: a new drug in development for schizophrenia | Full Text | References | PDF (451.9 KB)

1379 Views
108 CrossRef citations
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Article

Darinaparsin: a novel organic arsenical with promising anticancer activity

Koren K Mann, Barbara Wallner, Izidore S Lossos & Wilson H Miller Jr

Pages: 1727-1734

Published online: 23 Oct 2009

AbstractforDarinaparsin: a novel organic arsenical with promising anticancer activity | Full Text | References | PDF (1.5 MB)

471 Views
58 CrossRef citations
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Article

Neratinib: an oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer

Prithviraj Bose MD & Howard Ozer MD PhD

Pages: 1735-1751

Published online: 28 Sep 2009

AbstractforNeratinib: an oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer | Full Text | References | PDF (2 MB)

876 Views
58 CrossRef citations
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Article

Vilazodone, a novel dual-acting serotonergic antidepressant for managing major depression

Arif Khan MD

Pages: 1753-1764

Published online: 21 Sep 2009

AbstractforVilazodone, a novel dual-acting serotonergic antidepressant for managing major depression | Full Text | References | PDF (374.2 KB)

879 Views
49 CrossRef citations
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Article

SR 57746A/xaliproden, a non-peptide neurotrophic compound: prospects and constraints for the treatment of nervous system diseases

Marc Porzner MD, Tobias Müller MD & Thomas Seufferlein MD

Pages: 1765-1772

Published online: 09 Oct 2009

AbstractforSR 57746A/xaliproden, a non-peptide neurotrophic compound: prospects and constraints for the treatment of nervous system diseases | Full Text | References | PDF (237 KB)

166 Views
8 CrossRef citations
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Article

Vicriviroc: a CCR5 antagonist for treatment-experienced patients with HIV-1 infection

Tim Kümmerle, Clara Lehmann, Pia Hartmann, Christoph Wyen & Gerd Fätkenheuer

Pages: 1773-1785

Published online: 04 Nov 2009

AbstractforVicriviroc: a CCR5 antagonist for treatment-experienced patients with HIV-1 infection | Full Text | References | PDF (397 KB)

118 Views
6 CrossRef citations
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Article

Satraplatin: leading the new generation of oral platinum agents

Ashish Bhargava MD & Ulka N Vaishampayan MD

Pages: 1787-1797

Published online: 04 Nov 2009

AbstractforSatraplatin: leading the new generation of oral platinum agents | Full Text | References | PDF (299.4 KB)

345 Views
99 CrossRef citations
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