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‘Latest articles’ are articles accepted for publication in this journal but not yet published in a volume/issue. Articles are removed from the ‘Latest articles’ list when they are published in a volume/issue. Latest articles are citable using the author(s), year of online publication, article title, journal and article DOI.

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Review Article

Review Article
Pharmacokinetic evaluation of Donanemab for the treatment of Alzheimer’s
Tanya Song, Yunfei Wang, Bret David Silverglate & George T Grossberg
Accepted author version posted online: 17 May 2024
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Review Article

Review Article
The role of the circadian timing system on drug metabolism and detoxification: an update
Alper Okyar, Dilek Ozturk Civelek, Yasemin Kubra Akyel, Saliha Surme, Zeliha Pala Kara & İ. Halil Kavakli
Accepted author version posted online: 16 May 2024
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Review Article

Review Article
Recent progress in machine learning approaches for predicting carcinogenicity in drug development
Nguyen Quoc Khanh Le, Thi-Xuan Tran, Phung-Anh Nguyen, Trang-Thi Ho & Van-Nui Nguyen
Accepted author version posted online: 14 May 2024
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Review

Review Article
Pharmacokinetic and toxicological considerations affecting antiretroviral drug dosing in pregnant women
Zoran Todorović, Gordana Dragović & Relja Lukić
Published online: 14 May 2024
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Special Report

Report
New approach methods on the bench side to accelerate clinical trials during pregnancy
Ramkumar Menon, Lauren Richardson & Ananth Kumar Kammala
Published online: 13 May 2024
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Original Research

Article
Induction effect of antiretroviral bictegravir on the expression of Abcb1, Abcg2 and Abcc1 genes associated with P-gp, BCRP and MRP1 transporters present in rat peripheral blood mononuclear cells
Tarang Jadav, Niraj Rajput, Hemant Kumar, Santosh Kumar Behera & Pinaki Sengupta
Published online: 13 May 2024
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Drug Evaluation

Review Article
Evaluating the pharmacokinetics of upadacitinib for the treatment of moderate-to-severe Crohn’s disease
Ilaria Faggiani, Ferdinando D’Amico, Francesca Bernardi, Sarah Bencardino, Mariangela Allocca, Federica Furfaro, Tommaso Lorenzo Parigi, Alessandra Zilli, Gionata Fiorino, Laurent Peyrin-Biroulet & Silvio Danese
Published online: 13 May 2024
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Review

Review Article
Interactions between grapefruit juice and psychotropic medications: an update of the literature and an original case series
Marcin Siwek, Anna Julia Krupa & Jarosław Woroń
Published online: 09 May 2024
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Original Research

Article
Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: in vitro and pharmacoepidemiological approaches
Ayako Moriyama, Hinata Ueda, Katsuya Narumi, Shuho Asano, Ayako Furugen, Yoshitaka Saito & Masaki Kobayashi
Published online: 09 May 2024
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Review

Review Article
Interactions between antiepileptic drugs and direct oral anticoagulants for primary and secondary stroke prevention
Claudia Stöllberger, Josef Finsterer & Birke Schneider
Published online: 09 May 2024
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Editorial

Editorial
In NAMs we trust – an innovative paradigm-shift in risk-based chemicals management for globally harmonized protection goals
Camilla Alexander-White
Published online: 09 May 2024
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Free Access

Editorial

Editorial
Cephalosporins with warfarin increase the risk of bleeding: myth or fact?
Abrar K. Thabit, Samaher Y. Almoalim & Rahaf Altalhi
Published online: 09 May 2024
  • 160 Views
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Free Access

Review

Review Article
Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review
Yaping Liu, Jiapeng Li & Hao-Jie Zhu
Published online: 06 May 2024
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Review

Review Article
Pharmacokinetic considerations for drugs that treat diarrhea-predominant irritable bowel syndrome: what’s new?
Shilan Mozaffari, Shekoufeh Nikfar & Mohammad Abdollahi
Published online: 02 May 2024
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Review

Review Article
Optimizing co-prescription of clozapine and antiseizure medications: a systematic review and expert recommendations for clinical practice
Hélène Verdoux, Clélia Quiles & Jose de Leon
Published online: 18 Apr 2024
  • 201 Views
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Editorial

Editorial
Bioactivity descriptors for in vivo toxicity prediction: now and the future
Palle Helmke, Barbara Füzi & Gerhard F. Ecker
Published online: 04 Apr 2024
  • 264 Views
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Free Access

Review

Review Article
Beyond the hype and toward application: liver complex in vitro models in preclinical drug safety
Sushma Jadalannagari & Lorna Ewart
Published online: 13 Mar 2024
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Open Access

Review

Review Article
In-silico approaches to assessing multiple high-level drug-drug and drug-disease adverse drug effects
Xuan Xu, Jim E Riviere, Shahzad Raza, Nuwan Indika Millagaha Gedara, Remya Ampadi Ramachandran, Lisa A Tell, Gerald J. Wyckoff & Majid Jaberi-Douraki
Published online: 01 Feb 2024
  • 641 Views
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Open Access

Review

Review Article
Where developmental toxicity meets explainable artificial intelligence: state-of-the-art and perspectives
Maria Vittoria Togo, Fabrizio Mastrolorito, Angelica Orfino, Elisabetta Anna Graps, Anna Rita Tondo, Cosimo Damiano Altomare, Fulvio Ciriaco, Daniela Trisciuzzi, Orazio Nicolotti & Nicola Amoroso
Published online: 23 Dec 2023
  • 145 Views
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Editorial

Editorial
Overcoming barriers to machine learning applications in toxicity prediction
Abdallah Abou Hajal & Ahmad Z. Al Meslamani
Published online: 13 Dec 2023
  • 714 Views
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Free Access

Research Article

Article
In-depth mechanistic analysis including high-throughput RNA sequencing in the prediction of functional and structural cardiotoxicants using hiPSC cardiomyocytes
Alicia Rosell-Hidalgo, Christopher Bruhn, Emma Shardlow, Ryan Barton, Stephanie Ryder, Timur Samatov, Alexandra Hackmann, Gerald Ryan Aquino, Micael Fernandes Dos Reis, Vladimir Galatenko, Ruediger Fritsch, Cord Dohrmann & Paul A Walker
Published online: 23 Nov 2023
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Open Access
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