Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 6 (2015)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 6 (2015)

See all volumes and issues
Vol 20, 2024 Vol 19, 2023 Vol 18, 2022 Vol 17, 2021 Vol 16, 2020 Vol 15, 2019 Vol 14, 2018 Vol 13, 2017 Vol 12, 2016 Volume 11, 2015 Vol 10, 2014 Vol 9, 2013 Vol 8, 2012 Vol 7, 2011 Vol 6, 2010 Vol 5, 2009 Vol 4, 2008 Vol 3, 2007 Vol 2, 2006 Vol 1, 2005
Download citations Download PDFs Download issue

Editorial

Editorial
Strategies to overcome statin intolerance
Aris P Agouridis, Devaki R Nair & Dimitri P Mikhailidis (Academic Head of Department) MD FRCP FRCPath
Pages: 851-855
Published online: 18 Mar 2015
AbstractforStrategies to overcome statin intolerance | Full Text | References | PDF (173.3 KB)
  • 1602 Views
  • 13 CrossRef citations
  • 0Altmetric
Free Access

Original Research

Article
Relative contributions of the major human CYP450 to the metabolism of icotinib and its implication in prediction of drug–drug interaction between icotinib and CYP3A4 inhibitors/inducers using physiologically based pharmacokinetic modeling
Jia Chen, Dongyang Liu, Xin Zheng, Qian Zhao, Ji Jiang & Pei Hu
Pages: 857-868
Published online: 08 Apr 2015
AbstractforRelative contributions of the major human CYP450 to the metabolism of icotinib and its implication in prediction of drug–drug interaction between icotinib and CYP3A4 inhibitors/inducers using physiologically based pharmacokinetic modeling | Full Text | References | PDF (788.2 KB)
  • 610 Views
  • 15 CrossRef citations
  • 0Altmetric

Review

Transgenic mice and metabolomics for study of hepatic xenobiotic metabolism and toxicity
Frank J Gonzalez, Zhong-Ze Fang & Xiaochao Ma
Pages: 869-881
Published online: 02 Apr 2015
AbstractforTransgenic mice and metabolomics for study of hepatic xenobiotic metabolism and toxicity | Full Text | References | PDF (974.3 KB)
  • 420 Views
  • 38 CrossRef citations
  • 0Altmetric
Antidepressant use in the elderly: the role of pharmacodynamics and pharmacokinetics in drug safety
Janet Sultana (PhD Student) MSc, Edoardo Spina (Professor of Pharmacology) MD PhD & Gianluca Trifirò (Associate Professor of Pharmacology) MD PhD
Pages: 883-892
Published online: 03 Mar 2015
AbstractforAntidepressant use in the elderly: the role of pharmacodynamics and pharmacokinetics in drug safety | Full Text | References | PDF (237 KB)
  • 1359 Views
  • 53 CrossRef citations
  • 0Altmetric
Pharmacokinetics of antiretrovirals in mucosal tissue
Mackenzie L Cottrell, Nithya Srinivas & Angela DM Kashuba PharmD DABCP
Pages: 893-905
Published online: 22 Mar 2015
AbstractforPharmacokinetics of antiretrovirals in mucosal tissue | Full Text | References | PDF (373.9 KB)
  • 415 Views
  • 29 CrossRef citations
  • 0Altmetric
Mechanisms and therapeutic potential of inhibiting drug efflux transporters
Anna Klukovits (Senior Scientist) PhD & Peter Krajcsi (Chief Scientific Officer) PhD
Pages: 907-920
Published online: 24 Mar 2015
AbstractforMechanisms and therapeutic potential of inhibiting drug efflux transporters | Full Text | References | PDF (333 KB)
  • 305 Views
  • 17 CrossRef citations
  • 0Altmetric
Dosing algorithms for initiation of immunosuppressive drugs in solid organ transplant recipients
Louise M Andrews MSc Pharm D, Natalia Riva MSc, Brenda C de Winter PhD, Dennis A Hesselink MD PhD, Saskia N de Wildt MD PhD, Karlien Cransberg MD PhD & Teun van Gelder MD PhD
Pages: 921-936
Published online: 12 Apr 2015
AbstractforDosing algorithms for initiation of immunosuppressive drugs in solid organ transplant recipients | Full Text | References | PDF (337.6 KB)
  • 853 Views
  • 26 CrossRef citations
  • 0Altmetric
Pharmacodynamic profile and drug interactions with non-vitamin K antagonist oral anticoagulants: implications for patients with atrial fibrillation
Qinmei Xiong MD, Yee C Lau & Gregory YH Lip (Professor) MD
Pages: 937-948
Published online: 22 Mar 2015
AbstractforPharmacodynamic profile and drug interactions with non-vitamin K antagonist oral anticoagulants: implications for patients with atrial fibrillation | Full Text | References | PDF (319.9 KB)
  • 684 Views
  • 3 CrossRef citations
  • 0Altmetric
Posttranscriptional regulation of uridine diphosphate glucuronosyltransferases
Zoe Riches & Abby C Collier
Pages: 949-965
Published online: 22 Mar 2015
AbstractforPosttranscriptional regulation of uridine diphosphate glucuronosyltransferases | Full Text | References | PDF (616.4 KB)
  • 316 Views
  • 14 CrossRef citations
  • 0Altmetric

Drug Evaluation

Pharmacokinetics, pharmacodynamics and clinical efficacy of abiraterone acetate for treating metastatic castration-resistant prostate cancer
Christopher Sejong Han, Rutveej Patel & Isaac Yi Kim
Pages: 967-975
Published online: 04 May 2015
AbstractforPharmacokinetics, pharmacodynamics and clinical efficacy of abiraterone acetate for treating metastatic castration-resistant prostate cancer | Full Text | References | PDF (227.9 KB)
  • 761 Views
  • 13 CrossRef citations
  • 0Altmetric
Pharmacokinetics and pharmacodynamics of ticagrelor when treating non-ST elevation acute coronary syndromes
Francesco Monitillo MD, Massimo Iacoviello MD PhD, Pasquale Caldarola MD, Roberto Valle MD, Mario Chiatto MD & Nadia Aspromonte MD
Pages: 977-993
Published online: 16 Apr 2015
AbstractforPharmacokinetics and pharmacodynamics of ticagrelor when treating non-ST elevation acute coronary syndromes | Full Text | References | PDF (574.8 KB)
  • 312 Views
  • 1 CrossRef citations
  • 0Altmetric
Pharmacokinetic and pharmacodynamic evaluation of aflibercept for the treatment of colorectal cancer
Enrique Sanz-Garcia MD, Tamara Saurí MD, Josep Tabernero MD PhD & Teresa Macarulla MD
Pages: 995-1004
Published online: 19 May 2015
AbstractforPharmacokinetic and pharmacodynamic evaluation of aflibercept for the treatment of colorectal cancer | Full Text | References | PDF (414.6 KB)
  • 387 Views
  • 2 CrossRef citations
  • 0Altmetric
Pharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes
André J Scheen
Pages: 1005-1020
Published online: 02 May 2015
AbstractforPharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes | Full Text | References | PDF (557.9 KB)
  • 612 Views
  • 8 CrossRef citations
  • 0Altmetric

Further Readings

Related articles
Page: 1021
Published online: 19 May 2015
CitationforRelated articles | Full Text | PDF (86.6 KB)
  • 32 Views
  • 0 CrossRef citations
  • 0Altmetric

Explore articles

Explore the most recently published articles

Pharmacokinetic evaluation of Donanemab for the treatment of Alzheimer’s
Tanya Song et al.
Review Article | Published online: 17 May 2024
The role of the circadian timing system on drug metabolism and detoxification: an update
Alper Okyar et al.
Review Article | Published online: 16 May 2024
Pharmacokinetic and toxicological considerations affecting antiretroviral drug dosing in pregnant women
Zoran Todorović et al.
Review Article | Published online: 14 May 2024
Recent progress in machine learning approaches for predicting carcinogenicity in drug development
Nguyen Quoc Khanh Le et al.
Review Article | Published online: 14 May 2024
View all latest articles