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Volume 11, Issue 7

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 7 (2015)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 7 (2015)

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Editorial

Tissue-engineered blood vessels as promising tools for testing drug toxicity

George A Truskey & Cristina E Fernandez

Pages: 1021-1024

Published online: 31 May 2015

AbstractforTissue-engineered blood vessels as promising tools for testing drug toxicity | Full Text | References | PDF (139.2 KB)

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Editorial

Can pharmacogenomics help to improve therapy in patients with high-grade osteosarcoma?

Leo Kager MD, Christopher Diakos MD & Stefan Bielack MD

Pages: 1025-1028

Published online: 16 Apr 2015

AbstractforCan pharmacogenomics help to improve therapy in patients with high-grade osteosarcoma? | Full Text | References | PDF (140.8 KB)

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Original Research

Article

Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes

Danyi Lu, Dong Dong, Zhong Liu, Yifei Wang & Baojian Wu PhD

Pages: 1029-1040

Published online: 15 Jun 2015

AbstractforMetabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes | Full Text | References | PDF (1.3 MB) | Supplemental

162 Views
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Review

Neonatal medicines research: challenges and opportunities

Janko Samardzic, Mark A Turner, Ralph Bax & Karel Allegaert MD PhD

Pages: 1041-1052

Published online: 10 May 2015

AbstractforNeonatal medicines research: challenges and opportunities | Full Text | References | PDF (419.9 KB)

323 Views
10 CrossRef citations
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Mechanism of sulfotransferase pharmacogenetics in altered xenobiotic metabolism

Bo-Han Chen, Chen-Chu Wang, You-Hua Hou, Yi-Chih Mao & Yuh-Shyong Yang

Pages: 1053-1071

Published online: 15 Jun 2015

AbstractforMechanism of sulfotransferase pharmacogenetics in altered xenobiotic metabolism | Full Text | References | PDF (1.9 MB)

427 Views
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Measuring pharmacogenetics in special groups: geriatrics

Davide Seripa BiolD PhD, Francesco Panza MD, Julia Daragjati PharmD PhD, Giulia Paroni & Alberto Pilotto MD

Pages: 1073-1088

Published online: 19 May 2015

AbstractforMeasuring pharmacogenetics in special groups: geriatrics | Full Text | References | PDF (649 KB)

292 Views
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Influence of ethnicity on response to asthma drugs

Mario Cazzola (Professor) , Paola Rogliani, Alessandro Sanduzzi & Maria Gabriella Matera

Pages: 1089-1097

Published online: 20 May 2015

AbstractforInfluence of ethnicity on response to asthma drugs | Full Text | References | PDF (243.2 KB)

306 Views
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Small-molecule modulators of the constitutive androstane receptor

Milu T Cherian PhD, Sergio C Chai PhD & Taosheng Chen PhD

Pages: 1099-1114

Published online: 15 May 2015

AbstractforSmall-molecule modulators of the constitutive androstane receptor | Full Text | References | PDF (542.2 KB)

389 Views
27 CrossRef citations
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Tools for predicting the PK/PD of therapeutic proteins

Lei Diao PhD & Bernd Meibohm PhD FCP

Pages: 1115-1125

Published online: 04 May 2015

AbstractforTools for predicting the PK/PD of therapeutic proteins | Full Text | References | PDF (490 KB)

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Medication overuse and chronic migraine: a critical review according to clinical pharmacology

Anna Ferrari MD, Carlo Baraldi MD & Emilio Sternieri MD

Pages: 1127-1144

Published online: 31 May 2015

AbstractforMedication overuse and chronic migraine: a critical review according to clinical pharmacology | Full Text | References | PDF (352.2 KB)

535 Views
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Drug Evaluation

Pharmacokinetic and pharmacodynamic evaluation of ramelteon: an insomnia therapy

Gilberto Spadoni (Associate Professor) , Annalida Bedini (Assistant Professor) , Simone Lucarini (Assistant Professor) , Marco Mor (Full Professor) & Silvia Rivara (Associate Professor)

Pages: 1145-1156

Published online: 08 May 2015

AbstractforPharmacokinetic and pharmacodynamic evaluation of ramelteon: an insomnia therapy | Full Text | References | PDF (388.1 KB)

600 Views
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Pharmacokinetic and pharmacodynamic evaluation of telaprevir for the treatment of hepatitis C

Antonio Rivero-Juarez PhD, Angela Camacho MD PhD & Antonio Rivero MD PhD

Pages: 1157-1165

Published online: 25 May 2015

AbstractforPharmacokinetic and pharmacodynamic evaluation of telaprevir for the treatment of hepatitis C | Full Text | References | PDF (341 KB)

263 Views
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Pharmacokinetic and pharmacodynamic evaluation of raltegravir and experience from clinical trials in HIV-positive patients

Andrea Calcagno, Antonio D’Avolio & Stefano Bonora

Pages: 1167-1176

Published online: 15 Jun 2015

AbstractforPharmacokinetic and pharmacodynamic evaluation of raltegravir and experience from clinical trials in HIV-positive patients | Full Text | References | PDF (243 KB)

398 Views
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Evaluation of the pharmacokinetics of ixabepilone for the treatment of breast cancer

Antonella De Luca, Amelia D’Alessio, Monica Rosaria Maiello, Marianna Gallo, Nicoletta Chicchinelli, Maria Pergameno, Maria Sofia Piccirilli & Nicola Normanno

Pages: 1177-1185

Published online: 15 Jun 2015

AbstractforEvaluation of the pharmacokinetics of ixabepilone for the treatment of breast cancer | Full Text | References | PDF (258.2 KB)

214 Views
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Expert Opinion on Drug Metabolism & Toxicology (Vol.11, Iss.7, 2015)

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