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Volume 4, Issue 3

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 4, Issue 3 (2008)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 4, Issue 3 (2008)

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Reviews

Article

Genetic variations and gene expression of transporters in drug disposition and response

Ying Huang (Assistant Professor) MD PhD,, Sravan Penchala (Graduate Research Assistant) BPharm,, Anh-Nhan Pham (Graduate Research Assistant) BS, & Jeffrey Wang (Assistant Professor) PhD,

Pages: 237-254

Published online: 26 Mar 2008

AbstractforGenetic variations and gene expression of transporters in drug disposition and response | Full Text | References | PDF (487.9 KB)

158 Views
20 CrossRef citations
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Review

Article

Drug-induced phototoxicity evoked by inhibition of human ABC transporter ABCG2: development of in vitro high-speed screening systems

Ai Tamura, Ran An, Yuichiro Hagiya, Kazuyuki Hoshijima PhD, Takashi Yoshida PhD, Kenta Mikuriya PhD & Toshihisa Ishikawa PhD

Pages: 255-272

Published online: 26 Mar 2008

AbstractforDrug-induced phototoxicity evoked by inhibition of human ABC transporter ABCG2: development of in vitro high-speed screening systems | Full Text | References | PDF (1.1 MB)

275 Views
14 CrossRef citations
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Article

Target specificity and off-target effects as determinants of cancer drug efficacy

Maria C Shoshan MD & Stig Linder MD

Pages: 273-280

Published online: 26 Mar 2008

AbstractforTarget specificity and off-target effects as determinants of cancer drug efficacy | Full Text | References | PDF (121.4 KB)

476 Views
25 CrossRef citations
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Article

The hepatic safety profile of duloxetine: a review

Roger S McIntyre, Zilomi D Panjwani, Ha T Nguyen, Hanna O Woldeyohannes, Mohammad Alsuwaidan, Joanna K Soczynska, Maria T Lourenco, Jakub Z Konarski & Sidney H Kennedy

Pages: 281-285

Published online: 26 Mar 2008

AbstractforThe hepatic safety profile of duloxetine: a review | Full Text | References | PDF (106.1 KB)

541 Views
42 CrossRef citations
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Drug Evaluations

Article

An evaluation of rosuvastatin: pharmacokinetics, clinical efficacy and tolerability

John R Crouse III MD

Pages: 287-304

Published online: 26 Mar 2008

AbstractforAn evaluation of rosuvastatin: pharmacokinetics, clinical efficacy and tolerability | Full Text | References | PDF (249.6 KB)

710 Views
15 CrossRef citations
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Drug Evaluation

Article

Etanercept: an overview of its role in the treatment of psoriasis

Malini Patel Galindo MD, Brenda L Bartlett MD, Aron Gewirtzman MD, Natalia Mendoza MD MSc, Anne Marie Tremaine MD & Stephen K Tyring MD PhD

Pages: 305-310

Published online: 26 Mar 2008

AbstractforEtanercept: an overview of its role in the treatment of psoriasis | Full Text | References | PDF (108.1 KB)

121 Views
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Article

Mecasermin rinfabate: rhIGF-I/rhIGFBP-3 complex: iPLEX^™

Rachel M Williams, Anna McDonald, Martin O'Savage & David B Dunger

Pages: 311-324

Published online: 26 Mar 2008

AbstractforMecasermin rinfabate: rhIGF-I/rhIGFBP-3 complex: iPLEX^™ | Full Text | References | PDF (196 KB)

308 Views
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Article

Zolpidem extended-release: therapy for sleep induction and sleep maintenance difficulties

Gary Zammit PhD

Pages: 325-331

Published online: 26 Mar 2008

AbstractforZolpidem extended-release: therapy for sleep induction and sleep maintenance difficulties | Full Text | References | PDF (120.6 KB)

129 Views
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