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Volume 8, Issue 6

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 6 (2012)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 6 (2012)

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Research Article

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Page: 1

Published online: 18 May 2012

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Reviews

Review Article

Crystal structures of human sulfotransferases: insights into the mechanisms of action and substrate selectivity

Dong Dong, Roland Ako & Baojian Wu PhD

Pages: 635-646

Published online: 19 Apr 2012

AbstractforCrystal structures of human sulfotransferases: insights into the mechanisms of action and substrate selectivity | Full Text | References | PDF (890.5 KB)

488 Views
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Review Article

Novel models for assessing blood–brain barrier drug permeation

Werner J Geldenhuys, David D Allen & Jeffrey R Bloomquist

Pages: 647-653

Published online: 03 Apr 2012

AbstractforNovel models for assessing blood–brain barrier drug permeation | Full Text | References | PDF (285.4 KB)

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Review Article

Cytochrome c: potential as a noninvasive biomarker of drug-induced acute kidney injury

David M Small (PhD Student and Research Officer) & Glenda C Gobe (Co-Director, Associate Professor)

Pages: 655-664

Published online: 05 Apr 2012

AbstractforCytochrome c: potential as a noninvasive biomarker of drug-induced acute kidney injury | Full Text | References | PDF (272.6 KB)

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Review Article

The role of transporters in the toxicity of nucleoside and nucleotide analogs

Christopher A Koczor (Postdoctoral Fellow) , Rebecca A Torres (Postdoctoral Fellow) & William Lewis

Pages: 665-676

Published online: 18 Apr 2012

AbstractforThe role of transporters in the toxicity of nucleoside and nucleotide analogs | Full Text | References | PDF (276.9 KB)

530 Views
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Review Article

The effects of green tea polyphenols on drug metabolism

Chung S Yang (Professor) PhD & Eva Pan PharmD

Pages: 677-689

Published online: 18 Apr 2012

AbstractforThe effects of green tea polyphenols on drug metabolism | Full Text | References | PDF (351.7 KB)

729 Views
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Review Article

An update on the ability of St. John's wort to affect the metabolism of other drugs

Roja Rahimi & Mohammad Abdollahi (Professor)

Pages: 691-708

Published online: 18 May 2012

AbstractforAn update on the ability of St. John's wort to affect the metabolism of other drugs | Full Text | References | PDF (264.7 KB)

1469 Views
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Review Article

Pharmacokinetic and pharmacogenetic determinants and considerations in chemotherapy selection and dosing in infants

Janine R Hutson (MD/PhD Candidate) MSc, Sheila Weitzman (Staff Oncologist) MB BCh, Tal Schechter (Staff Oncologist) MD, Robert J Arceci (Chief) MD PhD, Richard B Kim (Chair) MD & Yaron Finkelstein (Staff physician) MD

Pages: 709-722

Published online: 18 Apr 2012

AbstractforPharmacokinetic and pharmacogenetic determinants and considerations in chemotherapy selection and dosing in infants | Full Text | References | PDF (287.6 KB)

261 Views
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Review Article

Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability – considerations for drug development

Yurong Lai, Manthena Varma, Bo Feng, Joel Clay Stephens, Emi Kimoto, Ayman El-Kattan, Katsuomi Ichikawa, Hironori Kikkawa, Chiho Ono, Akiyuki Suzuki, Misaki Suzuki, Yuichi Yamamoto & Larry Tremaine

Pages: 723-743

Published online: 18 Apr 2012

AbstractforImpact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability – considerations for drug development | Full Text | References | PDF (332.6 KB)

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Drug Evaluations

Article

Pharmacokinetic evaluation of atorvastatin and sitagliptin in combination for the treatment of type 2 diabetes

André J Scheen (Professor)

Pages: 745-758

Published online: 16 May 2012

AbstractforPharmacokinetic evaluation of atorvastatin and sitagliptin in combination for the treatment of type 2 diabetes | Full Text | References | PDF (339.9 KB)

556 Views
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Article

Evaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections

Joanne Livermore & William Hope (Professor of Therapeutics and Infectious Diseases)

Pages: 759-765

Published online: 25 Apr 2012

AbstractforEvaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections | Full Text | References | PDF (242.1 KB)

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Expert Opinion on Drug Metabolism & Toxicology (Vol.8, Iss.6, 2012)

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