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Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 8 (2012)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 8 (2012)

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Research Article

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Page: 1

Published online: 18 Jul 2012

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Original Research

Article

Single-dose pharmacokinetics and dose proportionality of intravenous pazufloxacin mesilate in healthy Korean volunteers

Joomi Lee, Sook Jin Seong, Mi-sun Lim, Sung Min Park, Jeonghyeon Park, Jeong Ju Seo, Hae Won Lee & Young-Ran Yoon (Clinical Professor) (Associate Professor)

Pages: 921-928

Published online: 18 Jul 2012

AbstractforSingle-dose pharmacokinetics and dose proportionality of intravenous pazufloxacin mesilate in healthy Korean volunteers | Full Text | References | PDF (318.4 KB)

198 Views
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Reviews

Review Article

Current regulatory approaches of bioequivalence testing

Vangelis Karalis (Lecturer in Pharmacokinetics) & Panos Macheras (Professor in Biopharmaceutics - Pharmacokinetics)

Pages: 929-942

Published online: 11 Jun 2012

AbstractforCurrent regulatory approaches of bioequivalence testing | Full Text | References | PDF (385.5 KB)

513 Views
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Review Article

Drug-drug interactions involving lysosomes: mechanisms and potential clinical implications

Randall Logan, Ryan S Funk (Pediatric Research Fellow) PharmD, PhD, Erick Axcell PharmD & Jeffrey P Krise (Associate Professor, Director of Graduate Studies) PhD

Pages: 943-958

Published online: 22 May 2012

AbstractforDrug-drug interactions involving lysosomes: mechanisms and potential clinical implications | Full Text | References | PDF (2.6 MB)

877 Views
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Review Article

The effects of alcohol on the metabolism and toxicology of anti-psoriasis drugs

Gino A Vena (Professor) MD & Nicoletta Cassano MD

Pages: 959-972

Published online: 17 May 2012

AbstractforThe effects of alcohol on the metabolism and toxicology of anti-psoriasis drugs | Full Text | References | PDF (235.7 KB)

435 Views
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Review Article

Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux

Chrisna Gouws, Dewald Steyn, Lissinda Du Plessis, Jan Steenekamp & Josias H Hamman

Pages: 973-984

Published online: 22 May 2012

AbstractforCombination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux | Full Text | References | PDF (277.5 KB)

551 Views
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Review Article

The early estimation of circulating drug metabolites in humans

Debra Luffer-Atlas PhD

Pages: 985-997

Published online: 10 Jun 2012

AbstractforThe early estimation of circulating drug metabolites in humans | Full Text | References | PDF (297.5 KB)

431 Views
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Review Article

Organotypic systems in drug metabolism and toxicity: challenges and opportunities

Ajit Dash MD PhD, Brett R Blackman & Brian R Wamhoff

Pages: 999-1014

Published online: 26 May 2012

AbstractforOrganotypic systems in drug metabolism and toxicity: challenges and opportunities | Full Text | References | PDF (613.6 KB)

484 Views
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Drug Evaluations

A preliminary evaluation of bardoxolone methyl for the treatment of diabetic nephropathy

Merlin Thomas (Professor)

Pages: 1015-1022

Published online: 30 Jun 2012

AbstractforA preliminary evaluation of bardoxolone methyl for the treatment of diabetic nephropathy | Full Text | References | PDF (224.3 KB)

653 Views
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Evaluation of verteporfin pharmakokinetics – redefining the need of photosensitizers in ophthalmology

Focke Ziemssen (Professor) & Heinrich Heimann

Pages: 1023-1041

Published online: 05 Jul 2012

AbstractforEvaluation of verteporfin pharmakokinetics – redefining the need of photosensitizers in ophthalmology | Full Text | References | PDF (326.4 KB)

516 Views
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Pharmacokinetic evaluation of zolmitriptan for the treatment of migraines

Luana Lionetto, Barbara Casolla, Fabiola Mastropietri, Lidia D'Alonzo, Andrea Negro, Maurizio Simmaco & Paolo Martelletti

Pages: 1043-1050

Published online: 05 Jul 2012

AbstractforPharmacokinetic evaluation of zolmitriptan for the treatment of migraines | Full Text | References | PDF (223.5 KB)

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Expert Opinion on Drug Metabolism & Toxicology (Vol.8, Iss.8, 2012)

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