Leukemia & Lymphoma, Volume 59, Issue 9 (2018)

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Leukemia & Lymphoma, Volume 59, Issue 9 (2018)

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Commentary

Lenalidomide in non-deletion 5q lower-risk myelodysplastic syndromes: a glass quarter full or three quarters empty?
Rory M. Shallis & Amer M. Zeidan
Pages: 2015-2017
Published online: 07 Feb 2018
First Page PreviewforLenalidomide in non-deletion 5q lower-risk myelodysplastic syndromes: a glass quarter full or three quarters empty? | Full Text | References | PDF (309.9 KB) | Supplemental
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Changing role of bone marrow examination in the diagnosis of hematological malignancies
Surender Juneja & David Westerman
Pages: 2018-2020
Published online: 12 Feb 2018
First Page PreviewforChanging role of bone marrow examination in the diagnosis of hematological malignancies | Full Text | References | PDF (299.1 KB) | Supplemental
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Review

Emerging molecular predictive and prognostic factors in acute myeloid leukemia
Shannon R. McCurdy & Mark J. Levis
Pages: 2021-2039
Published online: 02 Nov 2017
AbstractforEmerging molecular predictive and prognostic factors in acute myeloid leukemia | Full Text | References | PDF (1.3 MB) | Supplemental
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Building upon the success of CART19: chimeric antigen receptor T cells for hematologic malignancies
Antonia Rotolo, Anastasios Karadimitris & Marco Ruella
Pages: 2040-2055
Published online: 22 Nov 2017
AbstractforBuilding upon the success of CART19: chimeric antigen receptor T cells for hematologic malignancies | Full Text | References | PDF (1.7 MB) | Supplemental
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CAR T cell therapy for multiple myeloma: where are we now and where are we headed?
Arnab Ghosh, Sham Mailankody, Sergio A. Giralt, C. Ola Landgren, Eric L. Smith & Renier J. Brentjens
Pages: 2056-2067
Published online: 06 Nov 2017
AbstractforCAR T cell therapy for multiple myeloma: where are we now and where are we headed? | Full Text | References | PDF (1.6 MB) | Supplemental
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STAT3 inhibition as a therapeutic strategy for leukemia
Rubashruti Kanna, Gaurav Choudhary, Nandini Ramachandra, Ulrich Steidl, Amit Verma & Aditi Shastri
Pages: 2068-2074
Published online: 22 Nov 2017
AbstractforSTAT3 inhibition as a therapeutic strategy for leukemia | Full Text | References | PDF (913.4 KB) | Supplemental
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Original Article: Clinical

Improvement of fatigue, physical functioning, and well-being among patients with severe impairment at baseline receiving ibrutinib in combination with bendamustine and rituximab for relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma in the HELIOS study
Paula Cramer, Graeme Fraser, Rodrigo Santucci-Silva, Sebastian Grosicki, Marie-Sarah Dilhuydy, Ann Janssens, Javier Loscertales, Simon Rule, Andre Goy, Shana Traina, Eric K. H. Chan, Joris Diels, Nishan Sengupta, Michelle Mahler, Mariya Salman, Angela Howes & Asher Chanan-Khan
Pages: 2075-2084
Published online: 03 Jan 2018
AbstractforImprovement of fatigue, physical functioning, and well-being among patients with severe impairment at baseline receiving ibrutinib in combination with bendamustine and rituximab for relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma in the HELIOS study | Full Text | References | PDF (1.3 MB) | Supplemental
  • 4761 Views
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Open Access
Prognostic impact of activation-induced cytidine deaminase expression for patients with diffuse large B-cell lymphoma
Hiroshi Arima, Masakazu Fujimoto, Momoko Nishikori, Toshiyuki Kitano, Wataru Kishimoto, Masakatsu Hishizawa, Tadakazu Kondo, Kouhei Yamashita, Masahiro Hirata, Hironori Haga & Akifumi Takaori-Kondo
Pages: 2085-2095
Published online: 18 Dec 2017
AbstractforPrognostic impact of activation-induced cytidine deaminase expression for patients with diffuse large B-cell lymphoma | Full Text | References | PDF (2.2 MB) | Supplemental
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Decreased survival in hepatitis C patients with monomorphic post-transplant lymphoproliferative disorder after liver transplantation treated with frontline immunochemotherapy
Juan Pablo Alderuccio, Alexandra Stefanovic, Daniel Dammrich, Jennifer R. Chapman, Francisco Vega, Gennaro Selvaggi, Andreas Tzakis & Izidore S. Lossos
Pages: 2096-2104
Published online: 18 Dec 2017
AbstractforDecreased survival in hepatitis C patients with monomorphic post-transplant lymphoproliferative disorder after liver transplantation treated with frontline immunochemotherapy | Full Text | References | PDF (798.6 KB) | Supplemental
  • 278 Views
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Disease site as a determinant of survival outcome in patients with primary cutaneous peripheral T-cell lymphoma, unspecified: an analysis of 4057 cases from the US National Cancer Database
Chang Su, Kevin A. Nguyen, Harrison X. Bai, Ya Cao, Yongguang Tao, Giorgos Karakousis, Paul J. Zhang, Guiying Zhang & Rong Xiao
Pages: 2105-2112
Published online: 07 Dec 2017
AbstractforDisease site as a determinant of survival outcome in patients with primary cutaneous peripheral T-cell lymphoma, unspecified: an analysis of 4057 cases from the US National Cancer Database | Full Text | References | PDF (1 MB) | Supplemental
  • 315 Views
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Original Article: Research

Management of Hodgkin lymphoma in the era of brentuximab vedotin: real-world data from five European countries
Graham P. Collins, Antonio Rueda, Gilles Salles, Bastian von Tresckow & Francesco Zaja
Pages: 2113-2120
Published online: 16 Jan 2018
AbstractforManagement of Hodgkin lymphoma in the era of brentuximab vedotin: real-world data from five European countries | Full Text | References | PDF (1.3 MB) | Supplemental
  • 898 Views
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Original Article: Clinical

Bortezomib in combination with dose-adjusted EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin) induces long-term survival in patients with plasmablastic lymphoma: a retrospective analysis
Christopher Dittus, Natalie Grover, Steven Ellsworth, Xianming Tan & Steven I. Park
Pages: 2121-2127
Published online: 05 Jan 2018
AbstractforBortezomib in combination with dose-adjusted EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin) induces long-term survival in patients with plasmablastic lymphoma: a retrospective analysis | Full Text | References | PDF (758 KB) | Supplemental
  • 2270 Views
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A phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma
Mohamad Bassam Sonbol, Talal Hilal, Amylou C. Dueck, Allison C. Rosenthal, Christopher R. Conley, Heidi E. Kosiorek, Brenda F. Ginos, Katherine M. Gano, Craig S. Nichols, Jose F. Leis, Patrick B. Johnston, Thomas M. Habermann, Donald W. Northfelt, Peter Leif Bergsagel, David J. Inwards, Thomas E. Witzig, Stephen M. Ansell & Craig B. Reeder
Pages: 2128-2134
Published online: 10 Jan 2018
AbstractforA phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma | Full Text | References | PDF (741.9 KB) | Supplemental
  • 606 Views
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Safety profile of lenalidomide in patients with lower-risk myelodysplastic syndromes without del(5q): results of a phase 3 trial
Antonio Almeida, Pierre Fenaux, Guillermo Garcia-Manero, Stuart L. Goldberg, Stefanie Gröpper, Anna Jonasova, Norbert Vey, Carmen Castaneda, Jianhua Zhong, C. L. Beach & Valeria Santini
Pages: 2135-2143
Published online: 11 Jan 2018
AbstractforSafety profile of lenalidomide in patients with lower-risk myelodysplastic syndromes without del(5q): results of a phase 3 trial | Full Text | References | PDF (1.6 MB) | Supplemental
  • 660 Views
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Expression of multiple leukemic stem cell markers is associated with poor prognosis in de novo acute myeloid leukemia
Tomohiro Yabushita, Hironaga Satake, Hayato Maruoka, Mari Morita, Daisuke Katoh, Yoshimitsu Shimomura, Satoshi Yoshioka, Takeshi Morimoto & Takayuki Ishikawa
Pages: 2144-2151
Published online: 18 Dec 2017
AbstractforExpression of multiple leukemic stem cell markers is associated with poor prognosis in de novo acute myeloid leukemia | Full Text | References | PDF (1.1 MB) | Supplemental
  • 679 Views
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The impact of early molecular response in children and adolescents with chronic myeloid leukemia treated with imatinib: a single-center study from China
Haigang Shao, Zhao Zeng, Jiannong Cen, Jun Zhang, Shuxiao Bai, Chunxiao Wu, Yanlei Gong, Yong Wang, Huiying Qiu, Suning Chen & Jinlan Pan
Pages: 2152-2158
Published online: 15 Jan 2018
AbstractforThe impact of early molecular response in children and adolescents with chronic myeloid leukemia treated with imatinib: a single-center study from China | Full Text | References | PDF (793.8 KB)
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Original Article: Research

The genomic landscape of two Burkitt lymphoma cases and derived cell lines: comparison between primary and relapse samples
Claudia M. Wever, Dominique Geoffrion, Bruno M. Grande, Stephen Yu, Miguel Alcaide, Maryse Lemaire, Yasser Riazalhosseini, Josée Hébert, Christina Gavino, Donald C. Vinh, Tina Petrogiannis-Haliotis, Svetlana Dmitrienko, Koren K. Mann, Ryan D. Morin & Nathalie A. Johnson
Pages: 2159-2174
Published online: 03 Jan 2018
AbstractforThe genomic landscape of two Burkitt lymphoma cases and derived cell lines: comparison between primary and relapse samples | Full Text | References | PDF (3.4 MB) | Supplemental
  • 792 Views
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Prognostic significance of cathepsin L expression in pediatric acute myeloid leukemia
Garima Pandey, Sameer Bakhshi, Bhaskar Thakur, Prerna Jain & Shyam S. Chauhan
Pages: 2175-2187
Published online: 18 Jan 2018
AbstractforPrognostic significance of cathepsin L expression in pediatric acute myeloid leukemia | Full Text | References | PDF (1.3 MB) | Supplemental
  • 366 Views
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A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells
Zaw Min Oo, Anuradha Illendula, Jolanta Grembecka, Charles Schmidt, Yunpeng Zhou, Virginie Esain, Wanda Kwan, Isaura Frost, Trista E. North, Roger A. Rajewski, Nancy A. Speck & John H. Bushweller
Pages: 2188-2200
Published online: 18 Dec 2017
AbstractforA tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells | Full Text | References | PDF (3.5 MB) | Supplemental
  • 547 Views
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The molecular signature of AML with increased ALDH activity suggests a stem cell origin
Rachel Blume, Eugen Rempel, Linda Manta, Borhan R. Saeed, Wenwen Wang, Simon Raffel, Olga Ermakova, Volker Eckstein, Vladimir Benes, Andreas Trumpp, Anthony D. Ho & Christoph Lutz
Pages: 2201-2210
Published online: 16 Jan 2018
AbstractforThe molecular signature of AML with increased ALDH activity suggests a stem cell origin | Full Text | References | PDF (1.4 MB) | Supplemental
  • 515 Views
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Abundant expression of BMI1 in follicular lymphoma is associated with reduced overall survival
Naif AlJohani, Suk-Jin Choi, Andrew G. Day, Abdulmohsen Alhejaily, Shakeel Virk, Tara Baetz & David P. LeBrun
Pages: 2211-2219
Published online: 18 Dec 2017
AbstractforAbundant expression of BMI1 in follicular lymphoma is associated with reduced overall survival | Full Text | References | PDF (2.3 MB) | Supplemental
  • 254 Views
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DNA damage response-initiated cytokine secretion in bone marrow stromal cells promotes chemoresistance of myeloma cells
Hailong Tang, Mimi Shu, Bo Dai, Li Xu, Baoxia Dong, Guangxun Gao & Xiequn Chen
Pages: 2220-2226
Published online: 18 Dec 2017
AbstractforDNA damage response-initiated cytokine secretion in bone marrow stromal cells promotes chemoresistance of myeloma cells | Full Text | References | PDF (1.6 MB) | Supplemental
  • 376 Views
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Is bone marrow examination always necessary to establish the diagnosis of myelodysplastic syndromes? A proposed non-invasive diagnostic model
Howard S. Oster, Gal Carmi, Alex Kolomansky, Erel Joffe, Irit Kaye, Ilya Kirgner, Uri Greenbaum, Doron Comaneshter & Moshe Mittelman
Pages: 2227-2232
Published online: 02 Jan 2018
AbstractforIs bone marrow examination always necessary to establish the diagnosis of myelodysplastic syndromes? A proposed non-invasive diagnostic model | Full Text | References | PDF (602 KB) | Supplemental
  • 330 Views
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Letter to the Editor

Coincidence of 5q deletion and the JAK2V617F mutation: report of two patients with overlapping myelodysplastic and myeloproliferative features and review of the literature
Susanne Bürki, Evgenii Shumilov, Nicolas Bonadies, Johanna Flach, Myriam Legros, Yara Banz, Elisabeth Oppliger-Leibundgut, Martin Fiedler, Anne Angelillo-Scherrer, Alicia Rovo & Ulrike Bacher
Pages: 2233-2237
Published online: 03 Jan 2018
First Page PreviewforCoincidence of 5q deletion and the JAK2V617F mutation: report of two patients with overlapping myelodysplastic and myeloproliferative features and review of the literature | Full Text | References | PDF (493.8 KB) | Supplemental
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Outcomes with lower intensity therapy in TP53-mutated acute myeloid leukemia
Prajwal Boddu, Hagop Kantarjian, Farhad Ravandi, Guillermo Garcia-Manero, Gautam Borthakur, Michael Andreeff, Elias J. Jabbour, Christopher B. Benton, Courtney D. DiNardo, Marina Konopleva, Naval Daver, Keyur Patel, Koichi Takahashi, Rashmi Kanagal-Shamanna, Jorge Cortes & Tapan Kadia
Pages: 2238-2241
Published online: 17 Jan 2018
First Page PreviewforOutcomes with lower intensity therapy in TP53-mutated acute myeloid leukemia | Full Text | References | PDF (1.1 MB) | Supplemental
  • 771 Views
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Surface endoglin (CD105) expression on acute leukemia blast cells: an extensive flow cytometry study of 1002 patients
Vincenzo Cosimato, Giulia Scalia, Maddalena Raia, Laura Gentile, Vincenza Cerbone, Feliciano Visconte, Teodora Statuto, Luciana Valvano, Fiorella D’Auria, Giovanni Calice, Daniela Graziano, Pellegrino Musto & Luigi Del Vecchio
Pages: 2242-2245
Published online: 15 Jan 2018
First Page PreviewforSurface endoglin (CD105) expression on acute leukemia blast cells: an extensive flow cytometry study of 1002 patients | Full Text | References | PDF (554.5 KB) | Supplemental
  • 472 Views
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IRF2BP2-RARA t(1;17)(q42.3;q21.2) APL blasts differentiate in response to all-trans retinoic acid
Samir Mazharuddin, Anuja Chattopadhyay, Moshe Y. Levy & Robert L. Redner
Pages: 2246-2249
Published online: 19 Jan 2018
First Page PreviewforIRF2BP2-RARA t(1;17)(q42.3;q21.2) APL blasts differentiate in response to all-trans retinoic acid | Full Text | References | PDF (827 KB) | Supplemental
  • 311 Views
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CD33 splicing SNP regulates expression levels of CD33 in normal regenerating monocytes in AML patients
Jatinder K. Lamba, Andrew P. Voigt, Lata Chauhan, Miyoung Shin, Richard Aplenc, Lisa Eidenschink Brodersen, Alan S. Gamis, Soheil Meshinchi & Michael R. Loken
Pages: 2250-2253
Published online: 10 Jan 2018
First Page PreviewforCD33 splicing SNP regulates expression levels of CD33 in normal regenerating monocytes in AML patients | Full Text | References | PDF (529.2 KB) | Supplemental
  • 626 Views
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Incidence, racial disparities and survival outcomes of mast cell malignancies: analysis from a national database
Anuhya Kommalapati, Yevgeniya Kushchayeva & Sri Harsha Tella
Pages: 2254-2257
Published online: 03 Jan 2018
First Page PreviewforIncidence, racial disparities and survival outcomes of mast cell malignancies: analysis from a national database | Full Text | References | PDF (605.8 KB) | Supplemental
  • 279 Views
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Obinutuzumab monotherapy in previously untreated chronic lymphocytic leukemia
Nathan D. Gay, Eliana Kozin, Craig Okada, Alexey V. Danilov & Stephen Spurgeon
Pages: 2258-2260
Published online: 18 Dec 2017
First Page PreviewforObinutuzumab monotherapy in previously untreated chronic lymphocytic leukemia | Full Text | References | PDF (333.8 KB) | Supplemental
  • 636 Views
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Toxic epidermal necrolysis versus cutaneous Graft-Versus-Host Disease in a hematopoietic stem cell transplant recipient: the role of elafin
Alessandra Chen, Kevin Chao, Lina Rodriguez, William Munday & Scott Worswick
Pages: 2261-2263
Published online: 11 Jan 2018
First Page PreviewforToxic epidermal necrolysis versus cutaneous Graft-Versus-Host Disease in a hematopoietic stem cell transplant recipient: the role of elafin | Full Text | References | PDF (1 MB)
  • 358 Views
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Monitoring of leukemia stem cells in chronic myeloid leukemia patients
Jieke Cui, Zunmin Zhu, Songya Liu, Qing Li, Li Meng, Hui Cheng, Zhaodong Zhong, Weiming Li, Yong You, Xiaojian Zhu & Ping Zou
Pages: 2264-2266
Published online: 16 Jan 2018
First Page PreviewforMonitoring of leukemia stem cells in chronic myeloid leukemia patients | Full Text | References | PDF (400.5 KB) | Supplemental
  • 300 Views
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Chronic myelomonocytic leukemia with central nervous system involvement
Michelle Hannon, Lindsay Wilde, Nneamaka Nwaoduah & Margaret Kasner
Pages: 2267-2268
Published online: 11 Jan 2018
CitationforChronic myelomonocytic leukemia with central nervous system involvement | Full Text | References | PDF (259.9 KB) | Supplemental
  • 347 Views
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