Pharmaceutical Development and Technology, Volume 20, Issue 5 (2015)

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Pharmaceutical Development and Technology, Volume 20, Issue 5 (2015)

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Review Article

Review Article
Multivariate analysis in the pharmaceutical industry: enabling process understanding and improvement in the PAT and QbD era
Ana P. Ferreira & Mike Tobyn
Pages: 513-527
Published online: 18 Mar 2014
AbstractforMultivariate analysis in the pharmaceutical industry: enabling process understanding and improvement in the PAT and QbD era | Full Text | References | PDF (654.9 KB)
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Research Article

Article
Phenylalanine-free taste-masked orodispersible tablets of fexofenadine hydrochloride: development, in vitro evaluation and in vivo estimation of the drug pharmacokinetics in healthy human volunteers
Soad Ali Yehia, Mohamed Shafik El-Ridi, Mina Ibrahim Tadros & Nolwa Gamal El-Sherif
Pages: 528-539
Published online: 03 Feb 2014
AbstractforPhenylalanine-free taste-masked orodispersible tablets of fexofenadine hydrochloride: development, in vitro evaluation and in vivo estimation of the drug pharmacokinetics in healthy human volunteers | Full Text | References | PDF (1.7 MB)
  • 216 Views
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Article
Influence of dissolution media pH and USP1 basket speed on erosion and disintegration characteristics of immediate release metformin hydrochloride tablets
Divyakant Desai, Benjamin Wong, Yande Huang, Dan Tang, Jeffrey Hemenway, Srinivasa Paruchuri, Hang Guo, Daniel Hsieh & Peter Timmins
Pages: 540-545
Published online: 12 Mar 2014
AbstractforInfluence of dissolution media pH and USP1 basket speed on erosion and disintegration characteristics of immediate release metformin hydrochloride tablets | Full Text | References | PDF (322.5 KB)
  • 434 Views
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Article
Formulation of novel sustained release rifampicin-loaded solid lipid microparticles based on structured lipid matrices from Moringa oleifera
Ikechukwu V. Onyishi, Salome A. Chime & Echezona O. Ogudiegwu
Pages: 546-554
Published online: 25 Jun 2014
AbstractforFormulation of novel sustained release rifampicin-loaded solid lipid microparticles based on structured lipid matrices from Moringa oleifera | Full Text | References | PDF (824.7 KB)
  • 137 Views
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Article
Effect of lipid viscosity and high-pressure homogenization on the physical stability of “Vitamin E” enriched emulsion
Alaadin Alayoubi, Ahmed Abu-Fayyad, Mutasem M. Rawas-Qalaji, Paul W. Sylvester & Sami Nazzal
Pages: 555-561
Published online: 12 Mar 2014
AbstractforEffect of lipid viscosity and high-pressure homogenization on the physical stability of “Vitamin E” enriched emulsion | Full Text | References | PDF (509.2 KB)
  • 255 Views
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Article
Physicochemical stability of a new topical timolol 0.5% gel formulation for the treatment of infant hemangioma
V. Merino-Bohórquez, M. Casas, F. Caracuel, M. Cameán, M. J. Fernández-Anguita, G. Ramírez-Soto & M. J. Lucero
Pages: 562-569
Published online: 22 Jul 2014
AbstractforPhysicochemical stability of a new topical timolol 0.5% gel formulation for the treatment of infant hemangioma | Full Text | References | PDF (1 MB)
  • 241 Views
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Article
Impact of fillers on dissolution kinetic of fenofibrate dry foams
Elisabeth Lenz, Angela Sprunk, Peter Kleinebudde & Susanne Page
Pages: 570-578
Published online: 05 Jun 2014
AbstractforImpact of fillers on dissolution kinetic of fenofibrate dry foams | Full Text | References | PDF (1.4 MB)
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Article
Development of polymeric nanoparticles with highly entrapped herbal hydrophilic drug using nanoprecipitation technique: an approach of quality by design
Parameswara Rao Vuddanda, Amit Mishra, Sanjay Kumar Singh & Sanjay Singh
Pages: 579-587
Published online: 15 May 2014
AbstractforDevelopment of polymeric nanoparticles with highly entrapped herbal hydrophilic drug using nanoprecipitation technique: an approach of quality by design | Full Text | References | PDF (2.2 MB)
  • 434 Views
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Article
Design and evaluation of novel barrier layer technologies for controlling venlafaxine hydrochloride release from tablet dosage form
Nikhil Malewar, Makarand Avachat, Shirish Kulkarni & Varsha Pokharkar
Pages: 588-597
Published online: 23 Apr 2014
AbstractforDesign and evaluation of novel barrier layer technologies for controlling venlafaxine hydrochloride release from tablet dosage form | Full Text | References | PDF (1,021.9 KB)
  • 129 Views
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Article
Permeability enhancing lipid-based co-solvent and SEDDS formulations of SQ641, an antimycobacterial agent
Shravan K. Mutyam, Naveen K. Bejugam, Helen J. Parish, Venkata M. Reddy, Elena Bogatcheva & Gita N. Shankar
Pages: 598-607
Published online: 20 Jun 2014
AbstractforPermeability enhancing lipid-based co-solvent and SEDDS formulations of SQ641, an antimycobacterial agent | Full Text | References | PDF (1.9 MB)
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Article
Box–Behnken study design for optimization of bicalutamide-loaded nanostructured lipid carrier: stability assessment
Ritu Kudarha, Namdev L. Dhas, Abhijeet Pandey, Veena S. Belgamwar & Pradum P. Ige
Pages: 608-618
Published online: 02 May 2014
AbstractforBox–Behnken study design for optimization of bicalutamide-loaded nanostructured lipid carrier: stability assessment | Full Text | References | PDF (1.9 MB)
  • 285 Views
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Article
Equipment and method for in vitro release measurements on topical dosage forms
Maria Eugenia Sesto Cabral, Alberto Nicolas Ramos, Carla Agostina Cabrera, Juan Carlos Valdez & Silvia Nelina González
Pages: 619-625
Published online: 16 Oct 2014
AbstractforEquipment and method for in vitro release measurements on topical dosage forms | Full Text | References | PDF (302.4 KB)
  • 190 Views
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Article
Development of eye drops containing antihypertensive drugs: formulation of aqueous irbesartan/γCD eye drops
Phatsawee Jansook, Chutimon Muankaew, Einar Stefánsson & Thorsteinn Loftsson
Pages: 626-632
Published online: 23 Apr 2014
AbstractforDevelopment of eye drops containing antihypertensive drugs: formulation of aqueous irbesartan/γCD eye drops | Full Text | References | PDF (378.1 KB)
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Technical Note

A novel accelerated in vitro release method to evaluate the release of thymopentin from PLGA microspheres
Xiangyang Xie, Zhiping Li, Ling Zhang, Qiang Chi, Yanfang Yang, Hui Zhang, Yang Yang & Xingguo Mei
Pages: 633-640
Published online: 06 Mar 2014
AbstractforA novel accelerated in vitro release method to evaluate the release of thymopentin from PLGA microspheres | Full Text | References | PDF (1.3 MB)
  • 239 Views
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