Journal of Receptors and Signal Transduction, Volume 19, Issue 1-4 (1999)

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Journal of Receptors and Signal Transduction, Volume 19, Issue 1-4 (1999)

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Original Article

Article
Methodology of Receptor Research–-A Philosophical Perspective
Peter Janich
Pages: 1-14
Published online: 10 Jul 2009
AbstractforMethodology of Receptor Research–-A Philosophical Perspective | References | PDF (647.7 KB)
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Article
Chance Favors the Prepared Mind - From Serendipity to Rational Drug Design
Hugo Kubinyi
Pages: 15-39
Published online: 10 Jul 2009
AbstractforChance Favors the Prepared Mind - From Serendipity to Rational Drug Design | References | PDF (1.1 MB)
  • 433 Views
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Article
Receptors and Signalling Components of Plant Hormones
M. Iten, T. Hoffmann & E. Grill
Pages: 41-58
Published online: 10 Jul 2009
AbstractforReceptors and Signalling Components of Plant Hormones | References | PDF (745.8 KB)
  • 88 Views
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Article
Extracts and Constituents of Hypericum Perforatum Inhibit the Binding of Various Ligands to Recombinant Receptors Expressed with the Semliki Forest Virus System
U. Simmen, W. Burkard, K. Berger, W. Schaffner & K. Lundstrom
Pages: 59-74
Published online: 10 Jul 2009
AbstractforExtracts and Constituents of Hypericum Perforatum Inhibit the Binding of Various Ligands to Recombinant Receptors Expressed with the Semliki Forest Virus System | References | PDF (708.7 KB)
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Article
The Jak-Stat Pathway: Cytokine Signalling from the Receptor to the Nucleus
Markus H. Heim
Pages: 75-120
Published online: 10 Jul 2009
AbstractforThe Jak-Stat Pathway: Cytokine Signalling from the Receptor to the Nucleus | References | PDF (2.4 MB)
  • 2122 Views
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Article
Regulation of Protein Kinase B
R. Meier & B. A. Hemmings
Pages: 121-128
Published online: 10 Jul 2009
AbstractforRegulation of Protein Kinase B | References | PDF (345.5 KB)
  • 115 Views
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Article
Fluorine-18 Radiolabelling, Biodistribution Studies and Preliminary Pet Evaluation of a New Memantine Derivative for Imaging the NMDA Receptor
S. M. Ametamey, S. Samnick, K. L. Leenders, P. Vontobel, G. Quack, C. G. Parsons & P. A. Schubiger
Pages: 129-141
Published online: 10 Jul 2009
AbstractforFluorine-18 Radiolabelling, Biodistribution Studies and Preliminary Pet Evaluation of a New Memantine Derivative for Imaging the NMDA Receptor | References | PDF (539.5 KB)
  • 140 Views
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Article
Analysis of the Endocytic Pathway Upon Intracellular Transport of IgG Molecules Through Fc Receptors
I. Athanassakis, E. Protopapadakis & S. Vassiliadis
Pages: 143-154
Published online: 10 Jul 2009
AbstractforAnalysis of the Endocytic Pathway Upon Intracellular Transport of IgG Molecules Through Fc Receptors | References | PDF (841 KB)
  • 32 Views
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Article
TP5 Triggers Signal Transduction Involving Mitogen Activated Protein Kinases in Monocytes
S. Gonser, N. E. A. Crompton, P. J. A. Weber, A. G. Beck-Sickinger & G. Folkers
Pages: 155-166
Published online: 10 Jul 2009
AbstractforTP5 Triggers Signal Transduction Involving Mitogen Activated Protein Kinases in Monocytes | References | PDF (656.4 KB)
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Article
A Microplate Binding Assay for the Somatostatin Type-2 Receptor (SSTR2)
S. Froidevaux, M. Meier, M. Häusler, H. Mäcke, C. Beglinger & A. N. Eberle
Pages: 167-180
Published online: 10 Jul 2009
AbstractforA Microplate Binding Assay for the Somatostatin Type-2 Receptor (SSTR2) | References | PDF (588.6 KB)
  • 83 Views
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Article
Binding of Interleukin-13 and Interleukin-4 to the Interleukin (IL)-4/IL-13 Receptor of Human Synovial Fibroblasts
Rudolf A. Lutz, Ningping Feng & Rene Moser
Pages: 181-190
Published online: 10 Jul 2009
AbstractforBinding of Interleukin-13 and Interleukin-4 to the Interleukin (IL)-4/IL-13 Receptor of Human Synovial Fibroblasts | References | PDF (417.5 KB)
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Article
Participation of β-Adrenergic Receptors on Macrophages in Modulation of LPS-Induced Cytokine Release
C. A. Izeboud, J. A. J. Mocking, M. Monshouwer, A. S.J.P.A.M. van Miert & R. F. Witkamp
Pages: 191-202
Published online: 10 Jul 2009
AbstractforParticipation of β-Adrenergic Receptors on Macrophages in Modulation of LPS-Induced Cytokine Release | References | PDF (563.7 KB)
  • 364 Views
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Article
Melanocortin and leptin signaling systems: Central regulation of catabolic energy balance
Stewart L. Fisher, Keith A. Yagaloff & Paul Burn
Pages: 203-216
Published online: 10 Jul 2009
AbstractforMelanocortin and leptin signaling systems: Central regulation of catabolic energy balance | References | PDF (667.8 KB)
  • 53 Views
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Article
From Insulin Receptor Signalling to Glut 4 Translocation Abnormalities in Obesity and Insulin Resistance
Y. Le Marchand-Brustel, J-F. Tanti, M. Cormont, J-M. Ricort, T. Grémeaux & S. Grillo
Pages: 217-228
Published online: 10 Jul 2009
AbstractforFrom Insulin Receptor Signalling to Glut 4 Translocation Abnormalities in Obesity and Insulin Resistance | References | PDF (567.9 KB)
  • 155 Views
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Article
Genomic Organization and Mutational Analysis of the Human UCP2 Gene, a Prime Candidate Gene for Human Obesity
Klaus-Ulrich Lentes, Naxin Tu, Hongmei Chen, Ulrike Winnikes, Irmtraud Reinert, Gaby Marmann & Karl Martin Pirke
Pages: 229-244
Published online: 10 Jul 2009
AbstractforGenomic Organization and Mutational Analysis of the Human UCP2 Gene, a Prime Candidate Gene for Human Obesity | References | PDF (1.2 MB)
  • 89 Views
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Article
Splice Variants of the OB Receptor Gene are Differentially Expressed in Brain and Peripheral Tissues of Mice
Shu-Cheng Chen, Jarema P. Kochan, L. Arthur Campfield, Paul Burn & Richard J. Smeyne
Pages: 245-266
Published online: 10 Jul 2009
AbstractforSplice Variants of the OB Receptor Gene are Differentially Expressed in Brain and Peripheral Tissues of Mice | References | PDF (2.2 MB)
  • 82 Views
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Article
Binding of Long-Term Glycated Low Density Lipoprotein and Age- Albumin by Peripheral Monocytes and Endothelial Cells
G. Sobal, H. Sinzinger & E. J. Menzel
Pages: 267-281
Published online: 10 Jul 2009
AbstractforBinding of Long-Term Glycated Low Density Lipoprotein and Age- Albumin by Peripheral Monocytes and Endothelial Cells | References | PDF (650.9 KB)
  • 18 Views
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Article
Effect of Isoflavone Genistein on Insulin Receptors in Perfused Liver of Ovariectomized Rats
P. Mackowiak, L. Nogowski & K. W. Nowak
Pages: 283-292
Published online: 10 Jul 2009
AbstractforEffect of Isoflavone Genistein on Insulin Receptors in Perfused Liver of Ovariectomized Rats | References | PDF (420.2 KB)
  • 22 Views
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Article
Characterization of Ligand-Induced Conformational States in the β2 Adrenergic Receptor
Brian Kobilka, Ulrik Gether, Roland Seifert, Sansan Lin & Pejman Ghanouni
Pages: 293-300
Published online: 10 Jul 2009
AbstractforCharacterization of Ligand-Induced Conformational States in the β2 Adrenergic Receptor | References | PDF (377.5 KB)
  • 69 Views
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Article
Agonist-Specific Regulation of δ-Opioid Receptor Trafficking by G Protein-Coupled Receptor Kinase and β-Arrestin
Jie Zhang, Stephen S. G. Ferguson, Ping-Yee Law, Larry S. Barak & Marc G. Caron
Pages: 301-313
Published online: 10 Jul 2009
AbstractforAgonist-Specific Regulation of δ-Opioid Receptor Trafficking by G Protein-Coupled Receptor Kinase and β-Arrestin | References | PDF (880.3 KB)
  • 125 Views
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Article
Phosphorylation and Recycling Kinetics of g Protein-Coupled Receptors
Giulio Innamorati, Hamid Sadeghi & Mariel Birnbaumer
Pages: 315-326
Published online: 10 Jul 2009
AbstractforPhosphorylation and Recycling Kinetics of g Protein-Coupled Receptors | References | PDF (828.7 KB)
  • 78 Views
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Article
The Uncoupled State of the Human Formyl Peptide Receptor
Terri L. Gilbert, Eric R. Prossnitz & Larry A. Sklar
Pages: 327-340
Published online: 10 Jul 2009
AbstractforThe Uncoupled State of the Human Formyl Peptide Receptor | References | PDF (662.6 KB)
  • 17 Views
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Article
Molecular Modelling Studies on g Protein-Coupled Receptors: From Sequence to Structure?
A. S. Van Neuren, G. Müller, G. Klebe & L. Moroder
Pages: 341-353
Published online: 10 Jul 2009
AbstractforMolecular Modelling Studies on g Protein-Coupled Receptors: From Sequence to Structure? | References | PDF (567.6 KB)
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Article
Molecular Dynamics of a Vasopressin V2 Receptor in a Phospholipid Bilayer Membrane
Cezary Czaplewski, Marta Pasenkiewicz-Gierula & Jerzy Ciarkowski
Pages: 355-367
Published online: 10 Jul 2009
AbstractforMolecular Dynamics of a Vasopressin V2 Receptor in a Phospholipid Bilayer Membrane | References | PDF (1.2 MB)
  • 36 Views
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Article
Expression of the α1b-Adrenergic Receptor and G Protein Subunits in Mammalian Cell Lines Using the Semliki Forest Virus Expression System
A. Scheer, K. Björ Klöf, S. Cotecchia & K. Lundstrom
Pages: 369-378
Published online: 10 Jul 2009
AbstractforExpression of the α1b-Adrenergic Receptor and G Protein Subunits in Mammalian Cell Lines Using the Semliki Forest Virus Expression System | References | PDF (391.6 KB)
  • 19 Views
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Article
Comparison of Antibodies Directed Against Receptor Segments of NPY-Receptors
Christophe P. Eckard, Annette G. Beck-Sickinger & Heike A. Wieland
Pages: 379-394
Published online: 10 Jul 2009
AbstractforComparison of Antibodies Directed Against Receptor Segments of NPY-Receptors | References | PDF (826.2 KB)
  • 42 Views
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Article
Development of a Dual Glow-Signal Firefly and Renilla Luciferase Assay Reagent for the Analysis of G-Protein Coupled Receptor Signalling
J. Stables, S. Scott, S. Brown, C. Roelant, D. Burns, M. G. Lee & S. Rees
Pages: 395-410
Published online: 10 Jul 2009
AbstractforDevelopment of a Dual Glow-Signal Firefly and Renilla Luciferase Assay Reagent for the Analysis of G-Protein Coupled Receptor Signalling | References | PDF (623.5 KB)
  • 458 Views
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Article
Synthesis and Characterization of New Radioligands for the Mammalian Melanin-Concentrating Hormone (MCH) Receptor
E. Hintermann, R. Drozdz, H. Tanner & A. N. Eberle
Pages: 411-422
Published online: 10 Jul 2009
AbstractforSynthesis and Characterization of New Radioligands for the Mammalian Melanin-Concentrating Hormone (MCH) Receptor | References | PDF (525.7 KB)
  • 56 Views
  • 18 CrossRef citations
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Article
Fluorescent Muscarinic EGFP-hM1 Chimeric Receptors: Design, Ligand Binding and Functional Properties
C. Weill, B. Ilien, M. Goeldner & J.-L. Galzi
Pages: 423-436
Published online: 10 Jul 2009
AbstractforFluorescent Muscarinic EGFP-hM1 Chimeric Receptors: Design, Ligand Binding and Functional Properties | References | PDF (655.2 KB)
  • 53 Views
  • 8 CrossRef citations
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Article
Steady-State Binding of Adenine Nucleotides ATP, ADP and AMP to Rat Liver and Adipose Plasma Membranes
Gennady G. Yegutkin & Geoffrey Burnstock
Pages: 437-448
Published online: 10 Jul 2009
AbstractforSteady-State Binding of Adenine Nucleotides ATP, ADP and AMP to Rat Liver and Adipose Plasma Membranes | References | PDF (496.6 KB)
  • 30 Views
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Article
A Combinatorial Peptoid Library for the Identification of Novel MSH and GRP / Bombesin Receptor Ligands
G. Heizmann, P. Hildebrand, H. Tanner, S. Ketterer, A. Pansky, S. Froidevaux, C. Beglinger & A. N. Eberle
Pages: 449-466
Published online: 10 Jul 2009
AbstractforA Combinatorial Peptoid Library for the Identification of Novel MSH and GRP / Bombesin Receptor Ligands | References | PDF (788.6 KB)
  • 74 Views
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Article
Synthesis and Receptor Binding Analysis of Thirteen Oligomeric α-MSH Analogs
Yves Brandenburger, Keith Rose, Claudia Bagutti & Alex N. Eberle
Pages: 467-480
Published online: 10 Jul 2009
AbstractforSynthesis and Receptor Binding Analysis of Thirteen Oligomeric α-MSH Analogs | References | PDF (618.6 KB)
  • 22 Views
  • 9 CrossRef citations
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Article
Calcium Signalling and Gene Expression
Goedele van Haasteren, Senlin Li, Marco Muda, Stefan Susini & Werner Schlegel
Pages: 481-492
Published online: 10 Jul 2009
AbstractforCalcium Signalling and Gene Expression | References | PDF (597.8 KB)
  • 300 Views
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Article
Blue Native Page as a Useful Method for the Analysis of the Assembly of Distinct Combinations of Nicotinic Acetylcholine Receptor Subunits
A. Nicke, J. Rettinger, E. Mutschler & G. Schmalzing
Pages: 493-507
Published online: 10 Jul 2009
AbstractforBlue Native Page as a Useful Method for the Analysis of the Assembly of Distinct Combinations of Nicotinic Acetylcholine Receptor Subunits | References | PDF (810.5 KB)
  • 121 Views
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Article
Angiotensin II Type I Receptor Activation Modulates L- and T- Type Calcium Channel Activity Through Distinct Mechanisms in Bovine Adrenal Glomerulosa Cells
A. D. Maturana, M. M. Burnay, A. M. Capponi, M. B. Vallotton & M. F. Rossier
Pages: 509-520
Published online: 10 Jul 2009
AbstractforAngiotensin II Type I Receptor Activation Modulates L- and T- Type Calcium Channel Activity Through Distinct Mechanisms in Bovine Adrenal Glomerulosa Cells | References | PDF (490.9 KB)
  • 32 Views
  • 7 CrossRef citations
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Article
Synthesis and Electrophysiological Studies of a Novel Epibatidine Analogue
Jourg E. Spang, Jourg T. Patt, Sonia Bertrand, Daniel Bertrand, Gerrit Westera & P. August Schubiger
Pages: 521-531
Published online: 10 Jul 2009
AbstractforSynthesis and Electrophysiological Studies of a Novel Epibatidine Analogue | References | PDF (461.4 KB)
  • 20 Views
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Article
Fluorescence Techniques for Fundamental and Applied Studies of Membrane Protein Receptors: The 5-HT, Serotonin Receptor
Ruud Hovius, Evelyne L. Schmid, Ana-Paula Tairi, Horst Blasey, Alain R. Bernard, Kenneth Lundström & Horst Vogel
Pages: 533-545
Published online: 10 Jul 2009
AbstractforFluorescence Techniques for Fundamental and Applied Studies of Membrane Protein Receptors: The 5-HT, Serotonin Receptor | References | PDF (726.6 KB)
  • 43 Views
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Article
Reactive Affinity Probes for the Mapping of the Glycine-Binding Site of the NMDA Receptor NR1 Subunit
A. Kreimeyer, B. Laube, M. Sturgess, M. Goeldner & B. Foucaud
Pages: 547-557
Published online: 10 Jul 2009
AbstractforReactive Affinity Probes for the Mapping of the Glycine-Binding Site of the NMDA Receptor NR1 Subunit | References | PDF (505.5 KB)
  • 18 Views
  • 1 CrossRef citations
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Article
Benzophenone-Type Photoactivatable Derivatives of α-Neurotoxins and α-Conotoxins in Studies on Torpedo Nicotinic Acetylcholine Receptor
I. Kasheverov, M. Zhmak, E. Chivilyov, P. Saez-Brionez, Yu. Utkin, F. Hucho & V. Tsetlin
Pages: 559-571
Published online: 10 Jul 2009
AbstractforBenzophenone-Type Photoactivatable Derivatives of α-Neurotoxins and α-Conotoxins in Studies on Torpedo Nicotinic Acetylcholine Receptor | References | PDF (513.3 KB)
  • 42 Views
  • 12 CrossRef citations
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Article
Subtleties of Structure-Agonist Versus Antagonist Relationships of Opioid Peptides and Peptidomimetics
P. W. Schiller, G. Weltrowska, R. Schmidt, I. Berezowska, T.M.-D. Nguyen, C. Lemieux, N. N. Chung, K. A. Carpenter & B. C. Wilkes
Pages: 573-588
Published online: 10 Jul 2009
AbstractforSubtleties of Structure-Agonist Versus Antagonist Relationships of Opioid Peptides and Peptidomimetics | References | PDF (715.2 KB)
  • 37 Views
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Article
Functional Architecture of Vasopressin/Oxytocin Receptors
M. Hibert, J. Hoflack, S. Trumpp-Kallmeyer, B. Mouillac, B. Chini, E. Mahea, N. Cotte, S. Jard, M. Manning & C. Barberis
Pages: 589-596
Published online: 10 Jul 2009
AbstractforFunctional Architecture of Vasopressin/Oxytocin Receptors | References | PDF (368 KB)
  • 152 Views
  • 23 CrossRef citations
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Article
Partial Agonism: Mechanisms Based on Ligand-Receptor Interactions and on Stimulus-Response Coupling
Vladimir Pliska
Pages: 597-629
Published online: 10 Jul 2009
AbstractforPartial Agonism: Mechanisms Based on Ligand-Receptor Interactions and on Stimulus-Response Coupling | References | PDF (1.3 MB)
  • 183 Views
  • 15 CrossRef citations
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Article
Discovery and Design of Novel Vasopresses Hypotensive Pepitide Agonists
M. Manning, S. Stoev, L. L. Cheng, N. C. Wo & W. Y. Chan
Pages: 631-644
Published online: 10 Jul 2009
AbstractforDiscovery and Design of Novel Vasopresses Hypotensive Pepitide Agonists | References | PDF (623.8 KB)
  • 21 Views
  • 10 CrossRef citations
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Article
Structure-Based Design of Nonnatural Ligands for the HLA-B27 Protein
Seaverine Deadier, Stefan Krebs, Josea R. Lamas, Sorana Poenaru, Gerd Folkers, José A. López de Castro, Dieter Seebach & Didier Rognan
Pages: 645-657
Published online: 10 Jul 2009
AbstractforStructure-Based Design of Nonnatural Ligands for the HLA-B27 Protein | References | PDF (554.7 KB)
  • 24 Views
  • 10 CrossRef citations
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Article
Use of Mass Spectrometric Methods for Protein Identification in Receptor Research
P. Schrotz-King, M. Wilm, J. S. Andersen, K. Ashman, A. V. Podtelejnikov, A. Bachi, A. King & M. Mann
Pages: 659-672
Published online: 10 Jul 2009
AbstractforUse of Mass Spectrometric Methods for Protein Identification in Receptor Research | References | PDF (667.8 KB)
  • 54 Views
  • 6 CrossRef citations
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Article
Alphaviruses as Tools in Neurobiology and Gene Therapy
Kenneth Lundstrom
Pages: 673-686
Published online: 10 Jul 2009
AbstractforAlphaviruses as Tools in Neurobiology and Gene Therapy | References | PDF (665.6 KB)
  • 51 Views
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Article
Expression and Intracellular Localisation of Odorant Receptors in Mammalian Cell Lines Using Semliki Forest Virus Vectors
K. Monastyrskaia, F. Goepfert, R. Hochstrasser, G. Acunta, J. Leighton, J. R. Pink & K. Lundstrom
Pages: 687-701
Published online: 10 Jul 2009
AbstractforExpression and Intracellular Localisation of Odorant Receptors in Mammalian Cell Lines Using Semliki Forest Virus Vectors | References | PDF (1.5 MB)
  • 36 Views
  • 13 CrossRef citations
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Article
Enhanced Metallosorption of Escherichia Coli Cells Due to Surface Display of β- and α-Domains of Mammalian Metallothionein as a Fusion to Lamb Protein
Pavel Kotrba, Pavel Pospisil, Victor de Lorenzo & Tomas Ruml
Pages: 703-715
Published online: 10 Jul 2009
AbstractforEnhanced Metallosorption of Escherichia Coli Cells Due to Surface Display of β- and α-Domains of Mammalian Metallothionein as a Fusion to Lamb Protein | References | PDF (663.3 KB)
  • 49 Views
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Article
Simple and Fast Method to Test the Receptor for Advanced Glycosylated Endproducts (RAGE) For its Tumor Suppressive Potential Using the Tet-On System
I. Bendik, P. Schraml & C. U. Ludwig
Pages: 717-728
Published online: 10 Jul 2009
AbstractforSimple and Fast Method to Test the Receptor for Advanced Glycosylated Endproducts (RAGE) For its Tumor Suppressive Potential Using the Tet-On System | References | PDF (602.6 KB)
  • 30 Views
  • 3 CrossRef citations
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Article
Characterization of Transferrin Receptor in an Immortalized Cell Line of Rat Brain Endothelial Cells, RBE4
J. Huwyler, S. Froidevaux, F. Roux & A. M. Eberle
Pages: 729-739
Published online: 10 Jul 2009
AbstractforCharacterization of Transferrin Receptor in an Immortalized Cell Line of Rat Brain Endothelial Cells, RBE4 | References | PDF (747.5 KB)
  • 115 Views
  • 15 CrossRef citations
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Article
Specificity of Signaling by Hematopoietic Cytokine Receptors: Instructive Versus Permissive Effects
Radek C. Skoda
Pages: 741-772
Published online: 10 Jul 2009
AbstractforSpecificity of Signaling by Hematopoietic Cytokine Receptors: Instructive Versus Permissive Effects | References | PDF (1.6 MB)
  • 37 Views
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Miscellaneous Article

A Tribute to the Swiss Receptor Workshops and Scientific Meetings in General
Maurice Manning
Pages: 773-777
Published online: 10 Jul 2009
First Page PreviewforA Tribute to the Swiss Receptor Workshops and Scientific Meetings in General | PDF (225.8 KB)
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Workshop Synopsis Illustrated by Gerd Folkers
Pages: 779-780
Published online: 10 Jul 2009
CitationforWorkshop Synopsis Illustrated by Gerd Folkers | PDF (34.7 KB)
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List of Participants
Pages: xiii-xvi
Published online: 10 Jul 2009
First Page PreviewforList of Participants | PDF (176.9 KB)
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Preface
Pages: xvii-xviii
Published online: 10 Jul 2009
CitationforPreface | PDF (77.5 KB)
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Acknowledgement
Page: xix
Published online: 10 Jul 2009
CitationforAcknowledgement | PDF (31.8 KB)
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Receptor Research Prize 1998 sponsored by NEN Life Science Products
Pages: xxi-xxii
Published online: 10 Jul 2009
CitationforReceptor Research Prize 1998 sponsored by NEN Life Science Products | PDF (152.6 KB)
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Morschach: The Site of the Eighth Receptor Workshop
Pages: xxiii-xxvii
Published online: 10 Jul 2009
First Page PreviewforMorschach: The Site of the Eighth Receptor Workshop | PDF (156 KB)
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