Journal of Receptors and Signal Transduction, Volume 35, Issue 5 (2015)

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Journal of Receptors and Signal Transduction, Volume 35, Issue 5 (2015)

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Research Article

Article
Insight into the binding mode of a novel LSD1 inhibitor by molecular docking and molecular dynamics simulations
Xu Zhang, Mo Li, Yu Wang & Yi Zhao
Pages: 363-369
Published online: 12 Sep 2015
AbstractforInsight into the binding mode of a novel LSD1 inhibitor by molecular docking and molecular dynamics simulations | Full Text | References | PDF (1.6 MB)
  • 217 Views
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Article
Assessment of dual inhibition property of newly discovered inhibitors against PCAF and GCN5 through in silico screening, molecular dynamics simulation and DFT approach
Venkatesan Suryanarayanan & Sanjeev Kumar Singh
Pages: 370-380
Published online: 18 Nov 2014
AbstractforAssessment of dual inhibition property of newly discovered inhibitors against PCAF and GCN5 through in silico screening, molecular dynamics simulation and DFT approach | Full Text | References | PDF (1.3 MB)
  • 223 Views
  • 38 CrossRef citations
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Article
Susceptibility and progression of end stage renal disease are not associated with angiotensin II type 1 receptor gene polymorphism
Mariam Onsy F. Hanna, Rasha Mohamad Hosny Shahin, Safa S. Meshaal & Inas F. Kostandi
Pages: 381-385
Published online: 15 Oct 2014
AbstractforSusceptibility and progression of end stage renal disease are not associated with angiotensin II type 1 receptor gene polymorphism | Full Text | References | PDF (130.7 KB)
  • 68 Views
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Review Article

Estrogen-related receptor alpha and mitochondria: tale of the titans
Harmit S. Ranhotra
Pages: 386-390
Published online: 15 Sep 2014
AbstractforEstrogen-related receptor alpha and mitochondria: tale of the titans | Full Text | References | PDF (123.8 KB)
  • 740 Views
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Research Article

Article
Vitamin D receptor gene polymorphisms (TaqI and ApaI) in relation to 25-hydroxyvitamin D levels and coronary artery disease incidence
Mohamed A. Abu el Maaty, Sally I. Hassanein, Hameis M. Sleem & Mohamed Z. Gad
Pages: 391-395
Published online: 16 Sep 2014
AbstractforVitamin D receptor gene polymorphisms (TaqI and ApaI) in relation to 25-hydroxyvitamin D levels and coronary artery disease incidence | Full Text | References | PDF (127.3 KB)
  • 150 Views
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Article
Role of MAPK signal pathways in differentiation process of M2 macrophages induced by high-ambient glucose and TGF-β1
Ning Su, Yafang Li, Jie Wang, Jinjin Fan, Xiaoyan Li, Wenxing Peng, Xueqing Yu, Tian-Biao Zhou & Zongpei Jiang
Pages: 396-401
Published online: 09 Sep 2014
AbstractforRole of MAPK signal pathways in differentiation process of M2 macrophages induced by high-ambient glucose and TGF-β1 | Full Text | References | PDF (775.9 KB)
  • 395 Views
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Article
Activation of the bile acid receptor TGR5 enhances LPS-induced inflammatory responses in a human monocytic cell line
Kaia Mobraten, Tarjei Haugbro, Ellen Karlstrom, Charlotte R. Kleiveland & Tor Lea
Pages: 402-409
Published online: 24 Nov 2014
AbstractforActivation of the bile acid receptor TGR5 enhances LPS-induced inflammatory responses in a human monocytic cell line | Full Text | References | PDF (866.3 KB)
  • 898 Views
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Original Articles

Article
Potent inhibition of TGF-β signaling pathway regulator Abl: potential therapeutics for hepatic fibrosis
Kuifeng Wang, Yongzhi Tang, Fei Yan, Jiansheng Zhu & Jicheng Li
Pages: 410-419
Published online: 24 Nov 2014
AbstractforPotent inhibition of TGF-β signaling pathway regulator Abl: potential therapeutics for hepatic fibrosis | Full Text | References | PDF (2 MB)
  • 139 Views
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Review Article

Role of toll-like receptors in myocardial infarction
Yu Sun, Wen-Zhou Liu, Tao Liu, Xu Feng, Nuo Yang & Hua-Fu Zhou
Pages: 420-422
Published online: 17 Dec 2014
AbstractforRole of toll-like receptors in myocardial infarction | Full Text | References | PDF (103 KB)
  • 216 Views
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Research Article

Article
Study of naïve and memory cells in a cohort of Egyptian chronic granulomatous disease patients
Rabab El Hawary, Safa Meshaal, Diana Nagy, Ingy Fikry, Radwa Alkady, Dalia Abd Elaziz, Nermeen Galal, Jeannette Boutros, Aisha Elmarsafy & Reem Jan Farid
Pages: 423-428
Published online: 23 Mar 2015
AbstractforStudy of naïve and memory cells in a cohort of Egyptian chronic granulomatous disease patients | Full Text | References | PDF (118.5 KB)
  • 138 Views
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Article
The mechanism of protriptyline-induced Ca2+ movement and non-Ca2+-triggered cell death in PC3 human prostate cancer cells
Hong-Tai Chang, Chiang-Ting Chou, Chia-Cheng Yu, Jeng-Yu Tsai, Te-Kung Sun, Wei-Zhe Liang, Ko-Long Lin, Hui-Wen Tseng, Chun-Chi Kuo, Fu-An Chen, Daih-Huang Kuo, Chih-Chuan Pan, Chin-Man Ho, Pochuen Shieh & Chung-Ren Jan
Pages: 429-434
Published online: 22 Jun 2015
AbstractforThe mechanism of protriptyline-induced Ca2+ movement and non-Ca2+-triggered cell death in PC3 human prostate cancer cells | Full Text | References | PDF (300.9 KB)
  • 109 Views
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Review Article

Signaling pathway factors expression in renal tissue of apoE-knockout mice
Tian-Biao Zhou
Pages: 435-438
Published online: 22 Jun 2015
AbstractforSignaling pathway factors expression in renal tissue of apoE-knockout mice | Full Text | References | PDF (109.5 KB)
  • 285 Views
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Original Paper

Article
Molecular insights of benzodipyrazole as CDK2 inhibitors: combined molecular docking, molecular dynamics, and 3D QSAR studies
Varun Guttikonda, Divya Raavi, Sasi Kala Maadwar & Deepak Reddy Gade
Pages: 439-449
Published online: 22 Apr 2015
AbstractforMolecular insights of benzodipyrazole as CDK2 inhibitors: combined molecular docking, molecular dynamics, and 3D QSAR studies | Full Text | References | PDF (3.1 MB) | Supplemental
  • 178 Views
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Research Article

Article
Protection of curcumin against amyloid-β-induced cell damage and death involves the prevention from NMDA receptor-mediated intracellular Ca2+ elevation
Han-Chang Huang, Ping Chang, Shu-Yan Lu, Bo-Wen Zheng & Zhao-Feng Jiang
Pages: 450-457
Published online: 08 Jun 2015
AbstractforProtection of curcumin against amyloid-β-induced cell damage and death involves the prevention from NMDA receptor-mediated intracellular Ca2+ elevation | Full Text | References | PDF (988.8 KB)
  • 304 Views
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Article
Effects of losartan on expression of monocyte chemoattractant protein-1 (MCP-1) in hyperuricemic nephropathy rats
Shengyou Yu, Qi Ren & Wei Wu
Pages: 458-461
Published online: 01 Apr 2015
AbstractforEffects of losartan on expression of monocyte chemoattractant protein-1 (MCP-1) in hyperuricemic nephropathy rats | Full Text | References | PDF (506.2 KB)
  • 103 Views
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Article
Expression of Duffy antigen receptor for chemokines (DARC) is down-regulated in colorectal cancer
Shihang Zhou, Ming Liu, Ying Hu, Wanxin An, Xiaohua Liang, Weijian Yu & Fengyuan Piao
Pages: 462-467
Published online: 22 Jun 2015
AbstractforExpression of Duffy antigen receptor for chemokines (DARC) is down-regulated in colorectal cancer | Full Text | References | PDF (1.4 MB)
  • 139 Views
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Article
Structural insights of PA-824 derivatives: ligand-based 3D-QSAR study and design of novel PA824 derivatives as anti-tubercular agents
Bharathkumar Inturi, Gurubasavaraj V. Pujar & Madhusudhan N. Purohit
Pages: 468-478
Published online: 08 Jun 2015
AbstractforStructural insights of PA-824 derivatives: ligand-based 3D-QSAR study and design of novel PA824 derivatives as anti-tubercular agents | Full Text | References | PDF (1.2 MB)
  • 121 Views
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Review Article

Comparative transcriptional and translational analysis of heme oxygenase expression in response to sulfur mustard
Mohammad Reza Nourani, Hamideh Mahmoodzadeh Hosseini & Abbas Ali Imani Fooladi
Pages: 479-484
Published online: 22 Jun 2015
AbstractforComparative transcriptional and translational analysis of heme oxygenase expression in response to sulfur mustard | Full Text | References | PDF (317.2 KB)
  • 148 Views
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Research Article

Article
Identification of metals from osteoblastic ST-2 cell supernatants as novel OGR1 agonists
Rie Abe-Ohya, Tomio Ishikawa, Hideyuki Shiozawa, Koji Suda & Futoshi Nara
Pages: 485-492
Published online: 08 Jun 2015
AbstractforIdentification of metals from osteoblastic ST-2 cell supernatants as novel OGR1 agonists | Full Text | References | PDF (583.1 KB)
  • 231 Views
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Article
ANP and CNP activate CFTR expressed in Xenopus laevis oocytes by direct activation of PKA
Klaus Stahl, Maximilian Stahl, Hugo R. de Jonge & John N. Forrest Jr.
Pages: 493-504
Published online: 27 May 2015
AbstractforANP and CNP activate CFTR expressed in Xenopus laevis oocytes by direct activation of PKA | Full Text | References | PDF (709.9 KB)
  • 216 Views
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