Journal of Receptors and Signal Transduction, Volume 37, Issue 2 (2017)

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Journal of Receptors and Signal Transduction, Volume 37, Issue 2 (2017)

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Research Article

Article
Pharmacophore modeling, comprehensive 3D-QSAR, and binding mode analysis of TGR5 agonists
Thangaraj Sindhu & Pappu Srinivasan
Pages: 109-123
Published online: 07 Jun 2016
AbstractforPharmacophore modeling, comprehensive 3D-QSAR, and binding mode analysis of TGR5 agonists | Full Text | References | PDF (2.6 MB)
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Article
The role of α1-adrenergic receptors in regulating metabolism: increased glucose tolerance, leptin secretion and lipid oxidation
Ting Shi, Robert S. Papay & Dianne M. Perez
Pages: 124-132
Published online: 08 Jun 2016
AbstractforThe role of α1-adrenergic receptors in regulating metabolism: increased glucose tolerance, leptin secretion and lipid oxidation | Full Text | References | PDF (1.2 MB)
  • 302 Views
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Article
H4R activation utilizes distinct signaling pathways for the production of RANTES and IL-13 in human mast cells
Angel Jemima Ebenezer, Prema Arunachalam & Berla Thangam Elden
Pages: 133-140
Published online: 12 Jul 2016
AbstractforH4R activation utilizes distinct signaling pathways for the production of RANTES and IL-13 in human mast cells | Full Text | References | PDF (1.4 MB)
  • 230 Views
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Article
Persistent mechanical stretch-induced calcium overload and MAPK signal activation contributed to SCF reduction in colonic smooth muscle in vivo and in vitro
Fang Dong, Shu Yang, Haimei Sun, Jihong Yan, Xiaoxia Guo, Dandan Li & Deshan Zhou
Pages: 141-148
Published online: 12 Jul 2016
AbstractforPersistent mechanical stretch-induced calcium overload and MAPK signal activation contributed to SCF reduction in colonic smooth muscle in vivo and in vitro | Full Text | References | PDF (1.6 MB) | Supplemental
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Article
ERα dimerization: a key factor for the weak estrogenic activity of an ERα modulator unable to compete with estradiol in binding assays
Guy Leclercq, Ioanna Laïos, Céline Elie-Caille, Denis Leiber, Guy Laurent, Eric Lesniewska, Zahra Tanfin & Yves Jacquot
Pages: 149-166
Published online: 12 Jul 2016
AbstractforERα dimerization: a key factor for the weak estrogenic activity of an ERα modulator unable to compete with estradiol in binding assays | Full Text | References | PDF (4 MB)
  • 165 Views
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Article
Uric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFRβ
M. Kırça, N. Oğuz, A. Çetin, F. Uzuner & A. Yeşilkaya
Pages: 167-173
Published online: 12 Jul 2016
AbstractforUric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFRβ | Full Text | References | PDF (820.1 KB)
  • 387 Views
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Article
Dihydroartemisinin induces apoptosis in human gastric cancer cell line BGC-823 through activation of JNK1/2 and p38 MAPK signaling pathways
Shuyi Zhang, Lei Shi, Hongwen Ma, Hongzhou Li, Yanru Li, Ying Lu, Qiaoping Wang & Wen Li
Pages: 174-180
Published online: 12 Jul 2016
AbstractforDihydroartemisinin induces apoptosis in human gastric cancer cell line BGC-823 through activation of JNK1/2 and p38 MAPK signaling pathways | Full Text | References | PDF (1 MB)
  • 235 Views
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Article
Assessment of cell line competence for studies of pharmacological GPR30 modulation
Cátia Sousa, Madalena Ribeiro, Ana Teresa Rufino, Alcino Jorge Leitão & Alexandrina Ferreira Mendes
Pages: 181-188
Published online: 12 Jul 2016
AbstractforAssessment of cell line competence for studies of pharmacological GPR30 modulation | Full Text | References | PDF (1.5 MB)
  • 206 Views
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Article
Cholest-4-en-3-one attenuates TGF-β responsiveness by inducing TGF-β receptors degradation in Mv1Lu cells and colorectal adenocarcinoma cells
Chun-Lin Chen, Deng-Chyang Wu, Min-Yun Liu, Ming-Wei Lin, Hung-Tu Huang, Yaw-Bin Huang, Li-Chai Chen, Yu-Yu Chen, Jih-Jung Chen, Pei-Hua Yang, Yu-Chen Kao & Pei-Yu Chen
Pages: 189-199
Published online: 12 Jul 2016
AbstractforCholest-4-en-3-one attenuates TGF-β responsiveness by inducing TGF-β receptors degradation in Mv1Lu cells and colorectal adenocarcinoma cells | Full Text | References | PDF (2.6 MB) | Supplemental
  • 118 Views
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Review Article

Review
Cellular and molecular mechanisms of acute exposure to sulfur mustard: a systematic review
Mohammad Reza Nourani, Hamideh Mahmoodzadeh Hosseini, Sadegh Azimzadeh Jamalkandi & Abbas Ali Imani Fooladi
Pages: 200-216
Published online: 02 Aug 2016
AbstractforCellular and molecular mechanisms of acute exposure to sulfur mustard: a systematic review | Full Text | References | PDF (3.9 MB)
  • 387 Views
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