Journal of Receptors and Signal Transduction, Volume 38, Issue 3 (2018)

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Journal of Receptors and Signal Transduction, Volume 38, Issue 3 (2018)

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Research Article

Article
Antiproliferative and apoptosis-induction studies of 5-hydroxy 3′,4′,7-trimethoxyflavone in human breast cancer cells MCF-7: an in vitro and in silico approach
A. Sudha, P. Srinivasan, V. Kanimozhi, K. Palanivel & B. Kadalmani
Pages: 179-190
Published online: 08 May 2018
AbstractforAntiproliferative and apoptosis-induction studies of 5-hydroxy 3′,4′,7-trimethoxyflavone in human breast cancer cells MCF-7: an in vitro and in silico approach | Full Text | References | PDF (2.4 MB)
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Article
PPARgamma-mediated ALDH1A3 suppression exerts anti-proliferative effects in lung cancer by inducing lipid peroxidation
Tuyen N. M. Hua, Jun Namkung, Ai N. H. Phan, Vu T. A. Vo, Min-Kyu Kim, Yangsik Jeong & Jong-Whan Choi
Pages: 191-197
Published online: 06 Jun 2018
AbstractforPPARgamma-mediated ALDH1A3 suppression exerts anti-proliferative effects in lung cancer by inducing lipid peroxidation | Full Text | References | PDF (1,018.8 KB) | Supplemental
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Article
Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors
Mingdong Yu, Baohui Su & Xiaoxia Zhang
Pages: 198-203
Published online: 22 Jun 2018
AbstractforGardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors | Full Text | References | PDF (892.9 KB)
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Article
Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells
Angel Jemima Ebenezer, Kavya Prasad, Sanjana Rajan & Elden Berla Thangam
Pages: 204-212
Published online: 04 Jun 2018
AbstractforSilencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells | Full Text | References | PDF (1.3 MB)
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Article
Discovery of FIXa inhibitors by combination of pharmacophore modeling, molecular docking, and 3D-QSAR modeling
Penghua Li, Jiale Peng, Yeheng Zhou, Yaping Li, XingYong Liu, LiangLiang Wang & ZhiLi Zuo
Pages: 213-224
Published online: 04 May 2018
AbstractforDiscovery of FIXa inhibitors by combination of pharmacophore modeling, molecular docking, and 3D-QSAR modeling | Full Text | References | PDF (2.6 MB)
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Article
Atom-based 3D-QSAR, induced fit docking, and molecular dynamics simulations study of thieno[2,3-b]pyridines negative allosteric modulators of mGluR5
Sitrarasu Vijaya Prabhu & Sanjeev Kumar Singh
Pages: 225-239
Published online: 28 May 2018
AbstractforAtom-based 3D-QSAR, induced fit docking, and molecular dynamics simulations study of thieno[2,3-b]pyridines negative allosteric modulators of mGluR5 | Full Text | References | PDF (3.7 MB)
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Article
Computational and experimental validation of morin as adenosine deaminase inhibitor
K. G. Arun, C. S. Sharanya & C. Sadasivan
Pages: 240-245
Published online: 29 May 2018
AbstractforComputational and experimental validation of morin as adenosine deaminase inhibitor | Full Text | References | PDF (1.2 MB)
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Article
Pharmacophore modeling, molecular docking and molecular dynamics studies on natural products database to discover novel skeleton as non-purine xanthine oxidase inhibitors
Jiale Peng, Yaping Li, Yeheng Zhou, Li Zhang, Xingyong Liu & Zhili Zuo
Pages: 246-255
Published online: 29 May 2018
AbstractforPharmacophore modeling, molecular docking and molecular dynamics studies on natural products database to discover novel skeleton as non-purine xanthine oxidase inhibitors | Full Text | References | PDF (2.7 MB)
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Article
Designing of enzyme inhibitors based on active site specificity: lessons from methyl gallate and its lipoxygenase inhibitory profile
Sharanya C. S.Arun K. G.Vijaytha V.Sabu A.Haridas M.
Pages: 256-265
Published online: 30 May 2018
AbstractforDesigning of enzyme inhibitors based on active site specificity: lessons from methyl gallate and its lipoxygenase inhibitory profile | Full Text | References | PDF (2.4 MB) | Supplemental
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Article
Molecular dynamics and quantum chemistry-based approaches to identify isoform selective HDAC2 inhibitor – a novel target to prevent Alzheimer’s disease
Sanjay K. Choubey & Jeyaraman Jeyakanthan
Pages: 266-278
Published online: 22 Jun 2018
AbstractforMolecular dynamics and quantum chemistry-based approaches to identify isoform selective HDAC2 inhibitor – a novel target to prevent Alzheimer’s disease | Full Text | References | PDF (3.7 MB) | Supplemental
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