Xenobiotica, Volume 30, Issue 1 (2000)

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Xenobiotica, Volume 30, Issue 1 (2000)

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Research Article

Article
Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform
D. F. V. Lewis, M. G. Bird, M. Dickins, B. G. Lake, P. J. Eddershaw, M. H. Tarbit, P. S. Goldfarb
Pages: 1-25
Published online: 27 Aug 2009
AbstractforMolecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform | References | PDF (734.6 KB)
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Article
Cytochrome P450 enzyme activity and protein expression in primary porcine enterocyte and hepatocyte cultures
T. Hansen, J. Borlak, A. Bader
Pages: 27-46
Published online: 27 Aug 2009
AbstractforCytochrome P450 enzyme activity and protein expression in primary porcine enterocyte and hepatocyte cultures | References | PDF (887.6 KB)
  • 139 Views
  • 31 CrossRef citations
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Article
Interspecies comparison and role of human cytochrome P450 and flavin-containing monooxygenase in hepatic metabolism of L-775,606, a potent 5-HT1D receptor agonist
T. Prueksaritanont, P. Lu, L. Gorham, F. Sternfeld, K. P. Vyas
Pages: 47-59
Published online: 27 Aug 2009
AbstractforInterspecies comparison and role of human cytochrome P450 and flavin-containing monooxygenase in hepatic metabolism of L-775,606, a potent 5-HT1D receptor agonist | References | PDF (283.2 KB)
  • 76 Views
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Article
In vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: comparison with pioglitazone and rosiglitazone
H. Yamazaki, M. Suzuki, K. Tane, N. Shimada, M. Nakajima, T. Yokoi
Pages: 61-70
Published online: 27 Aug 2009
AbstractforIn vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: comparison with pioglitazone and rosiglitazone | References | PDF (227.5 KB)
  • 160 Views
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Article
Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes
N. Ishiguro, C. Senda, W. Kishimoto, K. Sakai, Y. Funae, T. Igarashi
Pages: 71-80
Published online: 27 Aug 2009
AbstractforIdentification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes | References | PDF (215.3 KB)
  • 198 Views
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Article
Pronounced differences in inhibition potency of lactone and non-lactone compounds for mouse and human coumarin 7-hydroxylases (CYP2A5 and CYP2A6)
R. O. Juvonen, J. Gynther, M. Pasanen, E. Alhava, A. Poso
Pages: 81-92
Published online: 27 Aug 2009
AbstractforPronounced differences in inhibition potency of lactone and non-lactone compounds for mouse and human coumarin 7-hydroxylases (CYP2A5 and CYP2A6) | References | PDF (256.6 KB)
  • 50 Views
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Article
Comparison of the pharmacokinetics of verapamil in the pregnant and non-pregnant rabbit: study of maternal and foetal tissue levels
C. Solans, M. A. Bregante, J. J. Aramayona, L. J. Fraile, M. A. Garcia
Pages: 93-102
Published online: 27 Aug 2009
AbstractforComparison of the pharmacokinetics of verapamil in the pregnant and non-pregnant rabbit: study of maternal and foetal tissue levels | References | PDF (190.2 KB)
  • 31 Views
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Article
Biotransformation of the xanthine oxidase inhibitor BOF-4272 and its metabolites in the liver and by the intestinal flora in rat
S. Naito, M. Nishimura
Pages: 103-109
Published online: 27 Aug 2009
AbstractforBiotransformation of the xanthine oxidase inhibitor BOF-4272 and its metabolites in the liver and by the intestinal flora in rat | References | PDF (167.3 KB)
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