Xenobiotica, Volume 39, Issue 10 (2009)

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Xenobiotica, Volume 39, Issue 10 (2009)

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Research Article

Article
Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp
Q.-R. Jin, W.-S. Shim, M.-K. Choi, G.-Y. Tian, I.-S. Song, S.-G. Yang, D.-D. Kim, S.-J. Chung & C.-K. Shim
Pages: 711-721
Published online: 24 Jun 2009
AbstractforDecreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp | Full Text | References | PDF (1 MB)
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Article
Metabolism-related liabilities of a potent histone deacetylase (HDAC) inhibitor and relevance of the route of administration on its metabolic fate
M. Fonsi, F. Fiore, P. Jones, O. Kinzel, R. Laufer, M. Rowley & E. Monteagudo
Pages: 722-737
Published online: 01 Jul 2009
AbstractforMetabolism-related liabilities of a potent histone deacetylase (HDAC) inhibitor and relevance of the route of administration on its metabolic fate | Full Text | References | PDF (1.4 MB)
  • 140 Views
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Article
Tissue-specific changes in mRNA expression of Abc and Slc transporters in murine pulmonary tuberculosis
S. H. Lee, T. Oh, B.-Y Jeon, E.-Y Kwak, W.-S Shim, S.-N Cho, D.-D Kim, S.-J Chung & C.-K Shim
Pages: 738-748
Published online: 08 Jul 2009
AbstractforTissue-specific changes in mRNA expression of Abc and Slc transporters in murine pulmonary tuberculosis | Full Text | References | PDF (668.3 KB)
  • 120 Views
  • 4 CrossRef citations
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Article
Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis
D. Ung, H. P. Parkman & S. Nagar
Pages: 749-756
Published online: 03 Jul 2009
AbstractforMetabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis | Full Text | References | PDF (883.7 KB)
  • 207 Views
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Article
Species-dependent hepatic metabolism of immunosuppressive agent tacrolimus (FK-506)
P. N. V. Tata, N. Subbotina, G. J. Burckart, D. C. Muddiman, A. I. Gusev, D. M. Hercules, T. E. Starzl & R. Venkataramanan
Pages: 757-765
Published online: 15 Jul 2009
AbstractforSpecies-dependent hepatic metabolism of immunosuppressive agent tacrolimus (FK-506) | Full Text | References | PDF (849.8 KB)
  • 238 Views
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Article
Pharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor α agonist in preclinical species and human
K.S. Frederick, T.S. Maurer, A.S. Kalgutkar, L.J. Royer, O.L. Francone, S.M. Winter, S.G. Terra, D. Chen & X. Gao
Pages: 766-781
Published online: 15 Jul 2009
AbstractforPharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor α agonist in preclinical species and human | Full Text | References | PDF (1.1 MB)
  • 237 Views
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Article
Blood gas partition coefficient and pulmonary extraction ratio for propofol in goats and pigs
M. Grossherr, A. Hengstenberg, L. Dibbelt, B.-W. Igl, R. Noel, A. v. d. Knesebeck, P. Schmucker & H. Gehring
Pages: 782-787
Published online: 23 Jun 2009
AbstractforBlood gas partition coefficient and pulmonary extraction ratio for propofol in goats and pigs | Full Text | References | PDF (640.8 KB)
  • 194 Views
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Article
Effects of the CYP2C9*13 allele on the pharmacokinetics of losartan in healthy male subjects
Z. Li, G. Wang, L.-S. Wang, W. Zhang, Z.-R. Tan, L. Fan, B.-L. Chen, Q. Li, J. Liu, J.-H. Tu, D.-L. Hu, Z.-Q. Liu & H.-H. Zhou
Pages: 788-793
Published online: 15 Jul 2009
AbstractforEffects of the CYP2C9*13 allele on the pharmacokinetics of losartan in healthy male subjects | Full Text | References | PDF (637.4 KB)
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