Autophagy, Volume 10, Issue 5 (2014)

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Autophagy, Volume 10, Issue 5 (2014)

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Editor's Corner

Editorial
Citing recent declines in the discovery of new ATG genes, some scientists now suggest that the end of autophagy research may be within sight
Daniel J Klionsky
Pages: 715-716
Published online: 07 Apr 2014
CitationforCiting recent declines in the discovery of new ATG genes, some scientists now suggest that the end of autophagy research may be within sight | Full Text | References | PDF (777.3 KB)
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Autophagy Community

Autophagy researchers
Pages: 717-720
Published online: 26 Mar 2014
First Page PreviewforAutophagy researchers | Full Text | PDF (948 KB)
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Artophagosome

Editorial
Macromusophagy
A solo piano musical representation of macroautophagy
Wendy W-K Lee & Daniel J Klionsky
Pages: 721-735
Published online: 14 Feb 2014
AbstractforMacromusophagy | Full Text | References | PDF (2.9 MB) | Supplemental
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Basic Research Paper

Article
The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation
Yuanzhi Lao, Gang Wan, Zhenyan Liu, Xiaoyu Wang, Ping Ruan, Wei Xu, Danqing Xu, Weidong Xie, Yaou Zhang, Hongxi Xu & Naihan Xu
Pages: 736-749
Published online: 14 Feb 2014
AbstractforThe natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation | Full Text | References | PDF (10.3 MB) | Supplemental
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Open Access
Article
Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation
Paola Matarrese, Tina Garofalo, Valeria Manganelli, Lucrezia Gambardella, Matteo Marconi, Maria Grasso, Antonella Tinari, Roberta Misasi, Walter Malorni & Maurizio Sorice
Pages: 750-765
Published online: 10 Feb 2014
AbstractforEvidence for the involvement of GD3 ganglioside in autophagosome formation and maturation | Full Text | References | PDF (3.7 MB) | Supplemental
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Article
Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression
Ji Wang, Rongyan Kang, He Huang, Xueyan Xi, Bei Wang, Jianwei Wang & Zhendong Zhao
Pages: 766-784
Published online: 20 Feb 2014
AbstractforHepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression | Full Text | References | PDF (6.2 MB) | Supplemental
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Article
The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy
Chul-Su Yang, Jwa-Jin Kim, Hye-Mi Lee, Hyo Sun Jin, Sang-Hee Lee, Ji-Hoon Park, Soung Jung Kim, Jin-Man Kim, Yong-Mahn Han, Myung-Shik Lee, Gi Ryang Kweon, Minho Shong & Eun-Kyeong Jo
Pages: 785-802
Published online: 25 Feb 2014
AbstractforThe AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy | Full Text | References | PDF (5.5 MB) | Supplemental
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Article
FGF7/KGF regulates autophagy in keratinocytes
A novel dual role in the induction of both assembly and turnover of autophagosomes
Francesca Belleudi, Valeria Purpura, Silvia Caputo & Maria Rosaria Torrisi
Pages: 803-821
Published online: 26 Feb 2014
AbstractforFGF7/KGF regulates autophagy in keratinocytes | Full Text | References | PDF (9.5 MB)
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Open Access
Article
Identification of autophagy as a longevity-assurance mechanism in the aging model Podospora anserina
Laura Knuppertz, Andrea Hamann, Francesco Pampaloni, Ernst Stelzer & Heinz D Osiewacz
Pages: 822-834
Published online: 27 Feb 2014
AbstractforIdentification of autophagy as a longevity-assurance mechanism in the aging model Podospora anserina | Full Text | References | PDF (2.9 MB) | Supplemental
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Open Access
Article
Deficiency of the exportomer components Pex1, Pex6, and Pex15 causes enhanced pexophagy in Saccharomyces cerevisiae
James M Nuttall, Alison M Motley & Ewald H Hettema
Pages: 835-845
Published online: 18 Mar 2014
AbstractforDeficiency of the exportomer components Pex1, Pex6, and Pex15 causes enhanced pexophagy in Saccharomyces cerevisiae | Full Text | References | PDF (2.2 MB) | Supplemental
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Article
Involvement of autophagy in hypoxic-excitotoxic neuronal death
Vanessa Ginet, Amélie Spiehlmann, Coralie Rummel, Nikita Rudinskiy, Yulia Grishchuk, Ruth Luthi-Carter, Peter GH Clarke, Anita C Truttmann & Julien Puyal
Pages: 846-860
Published online: 11 Mar 2014
AbstractforInvolvement of autophagy in hypoxic-excitotoxic neuronal death | Full Text | References | PDF (8.2 MB) | Supplemental
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Article
Size, stoichiometry, and organization of soluble LC3-associated complexes
Lewis J Kraft, Tuan A Nguyen, Steven S Vogel & Anne K Kenworthy
Pages: 861-877
Published online: 10 Mar 2014
AbstractforSize, stoichiometry, and organization of soluble LC3-associated complexes | Full Text | References | PDF (1.8 MB)
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Article
OsATG7 is required for autophagy-dependent lipid metabolism in rice postmeiotic anther development
Takamitsu Kurusu, Tomoko Koyano, Shigeru Hanamata, Takahiko Kubo, Yuhei Noguchi, Chikako Yagi, Noriko Nagata, Takashi Yamamoto, Takayuki Ohnishi, Yozo Okazaki, Nobutaka Kitahata, Daichi Ando, Masaya Ishikawa, Shinya Wada, Akio Miyao, Hirohiko Hirochika, Hiroaki Shimada, Amane Makino, Kazuki Saito, Hiroyuki Ishida, Tetsu Kinoshita, Nori Kurata & Kazuyuki Kuchitsu
Pages: 878-888
Published online: 24 Mar 2014
AbstractforOsATG7 is required for autophagy-dependent lipid metabolism in rice postmeiotic anther development | Full Text | References | PDF (2.4 MB) | Supplemental
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Article
BAX channel activity mediates lysosomal disruption linked to Parkinson disease
Jordi Bové, Marta Martínez-Vicente, Benjamin Dehay, Celine Perier, Ariadna Recasens, Agnes Bombrun, Bruno Antonsson & Miquel Vila
Pages: 889-900
Published online: 26 Mar 2014
AbstractforBAX channel activity mediates lysosomal disruption linked to Parkinson disease | Full Text | References | PDF (3 MB) | Supplemental
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Toolbox

Article
Development of a novel method for quantification of autophagic protein degradation by AHA labeling
Jianbin Zhang, Jigang Wang, Shukie Ng, Qingsong Lin & Han-Ming Shen
Pages: 901-912
Published online: 24 Mar 2014
AbstractforDevelopment of a novel method for quantification of autophagic protein degradation by AHA labeling | Full Text | References | PDF (2.1 MB) | Supplemental
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Protocol

Brief Report
iLIR
A web resource for prediction of Atg8-family interacting proteins
Ioanna Kalvari, Stelios Tsompanis, Nitha C Mulakkal, Richard Osgood, Terje Johansen, Ioannis P Nezis & Vasilis J Promponas
Pages: 913-925
Published online: 26 Feb 2014
AbstractforiLIR | Full Text | References | PDF (984.8 KB)
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Autophagic Punctum

Article Commentary
Arabidopsis ATG4 cysteine proteases specificity toward ATG8 substrates
Eunsook Park, Jongchan Woo & SP Dinesh-Kumar
Pages: 926-927
Published online: 20 Mar 2014
AbstractforArabidopsis ATG4 cysteine proteases specificity toward ATG8 substrates | Full Text | PDF (918.1 KB)
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Article Commentary
Vacuolar cell death in plants
Metacaspase releases the brakes on autophagy
Elena A Minina, Andrei P Smertenko & Peter V Bozhkov
Pages: 928-929
Published online: 27 Feb 2014
AbstractforVacuolar cell death in plants | Full Text | PDF (693 KB)
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Article Commentary
Dimethyl α-ketoglutarate inhibits maladaptive autophagy in pressure overload-induced cardiomyopathy
Guillermo Mariño, Federico Pietrocola, Yongli Kong, Tobias Eisenberg, Joseph A Hill, Frank Madeo & Guido Kroemer
Pages: 930-932
Published online: 20 Mar 2014
AbstractforDimethyl α-ketoglutarate inhibits maladaptive autophagy in pressure overload-induced cardiomyopathy | Full Text | PDF (849.7 KB)
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Article Commentary
Different phosphatidylinositol 3-phosphate asymmetries in yeast and mammalian autophagosomes revealed by a new electron microscopy technique
Toyoshi Fujimoto, Hayashi Yamamoto & Yoshinori Ohsumi
Pages: 933-935
Published online: 24 Mar 2014
AbstractforDifferent phosphatidylinositol 3-phosphate asymmetries in yeast and mammalian autophagosomes revealed by a new electron microscopy technique | Full Text | PDF (979.9 KB)
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Article Commentary
Plant autophagy is responsible for peroxisomal transition and plays an important role in the maintenance of peroxisomal quality
Michitaro Shibata, Kazusato Oikawa, Kohki Yoshimoto, Shino Goto-Yamada, Shoji Mano, Kenji Yamada, Maki Kondo, Makoto Hayashi, Wataru Sakamoto, Yoshinori Ohsumi & Mikio Nishimura
Pages: 936-937
Published online: 26 Mar 2014
AbstractforPlant autophagy is responsible for peroxisomal transition and plays an important role in the maintenance of peroxisomal quality | Full Text | PDF (753.4 KB)
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Article Addendum

Article Commentary
WITHDRAWN: Regulation of plasma membrane receptors by a new autophagy-related BECN/Beclin family member
Weiran Zhang & Congcong He
Pages: 938-941
Published online: 20 Feb 2014
AbstractforWITHDRAWN: Regulation of plasma membrane receptors by a new autophagy-related BECN/Beclin family member | PDF (184.9 KB)
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