Cancer Biology & Therapy, Volume 15, Issue 2 (2014)

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Cancer Biology & Therapy, Volume 15, Issue 2 (2014)

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Commentary

Article Commentary
When to screen and not to screen
Nichola Cruickshanks
Pages: 147-148
Published online: 14 Jan 2014
AbstractforWhen to screen and not to screen | Full Text | References | PDF (125.7 KB)
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Review

Review Article
Beyond abiraterone
New hormonal therapies for metastatic castration-resistant prostate cancer
Álvaro Pinto
Pages: 149-155
Published online: 01 Nov 2013
AbstractforBeyond abiraterone | Full Text | References | PDF (948 KB)
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Review Article
AMP-activated protein kinase (AMPK) beyond metabolism
A novel genomic stress sensor participating in the DNA damage response pathway
Toran Sanli, Gregory R Steinberg, Gurmit Singh & Theodoros Tsakiridis
Pages: 156-169
Published online: 01 Nov 2013
AbstractforAMP-activated protein kinase (AMPK) beyond metabolism | Full Text | References | PDF (2.5 MB)
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Journal Club

Bidirectional conversion of intestinal epithelial cells
NFκB is key
Amelie Boquoi
Pages: 170-171
Published online: 14 Jan 2014
AbstractforBidirectional conversion of intestinal epithelial cells | Full Text | References | PDF (707.4 KB)
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Bedside to Bench Report

Article
Reversion of erlotinib-acquired resistance twice by chemotherapy
A case report
Fei-fei Teng, Jian-dong Zhang, Xue Meng & Jin-ming Yu
Pages: 172-177
Published online: 06 Dec 2013
AbstractforReversion of erlotinib-acquired resistance twice by chemotherapy | Full Text | References | PDF (1.3 MB)
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Research Paper

Article
MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells
Lucy Liu, Nicolas Gaboriaud, Konstantina Vougogianopoulou, Yan Tian, Jun Wu, Wei Wen, Leandros Skaltsounis & Richard Jove
Pages: 178-184
Published online: 01 Nov 2013
AbstractforMLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells | Full Text | References | PDF (1.5 MB)
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Article
A comparative study of affibody, panitumumab, and EGF for near-infrared fluorescence imaging of EGFR- and EGFRvIII-expressing tumors
Haibiao Gong, Joy L Kovar, Lael Cheung, Eben L Rosenthal & D Michael Olive
Pages: 185-193
Published online: 01 Nov 2013
AbstractforA comparative study of affibody, panitumumab, and EGF for near-infrared fluorescence imaging of EGFR- and EGFRvIII-expressing tumors | Full Text | References | PDF (2.1 MB) | Supplemental
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Article
Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition
Anna Budina-Kolomets, Gregor M Balaburski, Anastasia Bondar, Neil Beeharry, Tim Yen & Maureen E Murphy
Pages: 194-199
Published online: 01 Nov 2013
AbstractforComparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Blood volatile compounds as biomarkers for colorectal cancer
Changsong Wang, Peng Li, Ailing Lian, Bo Sun, Xiaoyang Wang, Lei Guo, Chunjie Chi, Shanshan Liu, Wei Zhao, Suqi Luo, Zhigang Guo, Yang Zhang, Chaofu Ke, Guozhu Ye, Guowang Xu, Fengmin Zhang & Enyou Li
Pages: 200-206
Published online: 01 Nov 2013
AbstractforBlood volatile compounds as biomarkers for colorectal cancer | Full Text | References | PDF (1.5 MB)
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Article
Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with nilotinib against BCR-ABL-positive leukemia cells involves the ABL kinase domain mutation
Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Toshihiko Kitahara, Shinya Kimura, Taira Maekawa & Kazuma Ohyashiki
Pages: 207-215
Published online: 08 Nov 2013
AbstractforEfficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with nilotinib against BCR-ABL-positive leukemia cells involves the ABL kinase domain mutation | Full Text | References | PDF (3.1 MB)
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Article
Differentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential
Marie-Thérése Stockhausen, Karina Kristoffersen, Louise Stobbe & Hans Skovgaard Poulsen
Pages: 216-224
Published online: 01 Nov 2013
AbstractforDifferentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential | Full Text | References | PDF (1.3 MB)
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Article
Infrared microspectroscopy identifies biomolecular changes associated with chronic oxidative stress in mammary epithelium and stroma of breast tissues from healthy young women
Implications for latent stages of breast carcinogenesis
Imran I Patel, Debra A Shearer, Simon W Fogarty, Nigel J Fullwood, Luca Quaroni, Francis L Martin & Judith Weisz
Pages: 225-235
Published online: 01 Nov 2013
AbstractforInfrared microspectroscopy identifies biomolecular changes associated with chronic oxidative stress in mammary epithelium and stroma of breast tissues from healthy young women | Full Text | References | PDF (2.6 MB)
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Article
Irinotecan disrupts tight junction proteins within the gut
Implications for chemotherapy-induced gut toxicity
Hannah R Wardill, Joanne M Bowen, Noor Al-Dasooqi, Masooma Sultani, Emma Bateman, Romany Stansborough, Joseph Shirren & Rachel J Gibson
Pages: 236-244
Published online: 06 Dec 2013
AbstractforIrinotecan disrupts tight junction proteins within the gut | Full Text | References | PDF (1.8 MB)
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