Human Vaccines & Immunotherapeutics, Volume 10, Issue 7 (2014)

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Human Vaccines & Immunotherapeutics, Volume 10, Issue 7 (2014)

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Editor's Corner

Editorial
Letter from the Editor
Ronald Ellis & Eva M Riedmann
Pages: 1771-1772
Published online: 29 Sep 2014
CitationforLetter from the Editor | Full Text | PDF (145.3 KB)
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Portrait

Human Vaccines & Immunotherapeutics: News
Eva M. Riedmann
Pages: 1773-1777
Published online: 25 Aug 2014
AbstractforHuman Vaccines & Immunotherapeutics: News | PDF (171.5 KB)
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Portrait of Dr Michael G. Hanna, Jr
A pioneer in active specific immunotherapy of cancer
Michael Hanna Jr
Pages: 1778-1780
Published online: 21 Jul 2014
AbstractforPortrait of Dr Michael G. Hanna, Jr | Full Text | References | PDF (215.5 KB)
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Research Paper

Article
Efficacy of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical intraepithelial neoplasia and cervical infection in young Japanese women
Open follow-up of a randomized clinical trial up to 4 years post-vaccination
Ryo Konno, Hiroyuki Yoshikawa, Marie Okutani, Wim Quint, Pemmaraju V Suryakiran, Lan Lin & Frank Struyf
Pages: 1781-1794
Published online: 24 Apr 2014
AbstractforEfficacy of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical intraepithelial neoplasia and cervical infection in young Japanese women | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Projected impact of Cervarix® vaccination on oncogenic human papillomavirus infection and cervical cancer in the United Kingdom
Thierry Van Effelterre, Cosmina Hogea & Sylvia Taylor
Page: 1795
Published online: 07 Jul 2014
AbstractforProjected impact of Cervarix® vaccination on oncogenic human papillomavirus infection and cervical cancer in the United Kingdom | PDF (2.3 MB)
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Article
Immunogenicity and safety of the HPV-16/18 AS04-adjuvanted vaccine in healthy Chinese girls and women aged 9 to 45 years
Results from 2 randomized controlled trials
Fengcai Zhu, Juan Li, Yuemei Hu, Xiang Zhang, Xiaoping Yang, Hui Zhao, Junzhi Wang, Jianguo Yang, Guodong Xia, Qinyong Dai, Haiwen Tang, Pemmaraju V Suryakiran, Sanjoy K Datta, Dominique Descamps, Dan Bi & Frank Struyf
Pages: 1795-1806
Published online: 29 Apr 2014
AbstractforImmunogenicity and safety of the HPV-16/18 AS04-adjuvanted vaccine in healthy Chinese girls and women aged 9 to 45 years | Full Text | References | PDF (1.8 MB) | Supplemental
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Article
Effect of the decision-making process in the family on HPV vaccination rates among adolescents 9–17 years of age
Abbey B Berenson, Tabassum H Laz, Jacqueline M Hirth, Christine J McGrath & Mahbubur Rahman
Pages: 1807-1811
Published online: 29 Apr 2014
AbstractforEffect of the decision-making process in the family on HPV vaccination rates among adolescents 9–17 years of age | Full Text | References | PDF (643.3 KB)
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Review

Review Article
Human papillomaviruses-related cancers
Presence and prevention strategies in the Middle East and North African Regions
Ala-Eddin Al Moustafa, Rana Al-Awadhi, Nabiha Missaoui, Ishag Adam, Raika Durusoy, Lina Ghabreau, Nizar Akil, Hussain Gadelkarim Ahmed, Amber Yasmeen & Ghazi Alsbeih
Pages: 1812-1821
Published online: 30 Apr 2014
AbstractforHuman papillomaviruses-related cancers | Full Text | References | PDF (885.1 KB)
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Commentary

Dendritic cell immunotherapy in uterine cancer
An Coosemans, Sandra Tuyaerts, Anke Vanderstraeten, Ignace Vergote, Frédéric Amant & Stefaan W Van Gool
Pages: 1822-1827
Published online: 30 Apr 2014
AbstractforDendritic cell immunotherapy in uterine cancer | Full Text | References | PDF (689 KB)
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Research Paper

Article
Awareness and understanding of cancer immunotherapy in Europe
Håkan Mellstedt, Gustav Gaudernack, Winald R Gerritsen, Christoph Huber, Ignacio Melero, Giorgio Parmiani, Suzy Scholl, Nicholas Thatcher, John Wagstaff & Christoph Zielinski
Pages: 1828-1835
Published online: 28 Apr 2014
AbstractforAwareness and understanding of cancer immunotherapy in Europe | Full Text | References | PDF (1.5 MB)
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Article
Methionine enkephalin (MENK) improves lymphocyte subpopulations in human peripheral blood of 50 cancer patients by inhibiting regulatory T cells (Tregs)
Qiushi Wang, Xinghua Gao, Zhe Yuan, Zhe Wang, Yiming Meng, Yan Cao, Nicolas P Plotnikoff, Noreen Griffin & Fengping Shan
Pages: 1836-1840
Published online: 01 May 2014
AbstractforMethionine enkephalin (MENK) improves lymphocyte subpopulations in human peripheral blood of 50 cancer patients by inhibiting regulatory T cells (Tregs) | Full Text | References | PDF (870 KB)
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Article
A few years later
Update of the cost-effectiveness of infant pneumococcal vaccination in Dutch children
Pepijn Vemer & Maarten J Postma
Pages: 1841-1849
Published online: 08 May 2014
AbstractforA few years later | Full Text | References | PDF (898.5 KB)
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Article
Immunogenicity and safety of 13-valent pneumococcal conjugate vaccine when administered to healthy Japanese adults aged ≥50 years
An open-label trial
Masanari Shiramoto, Shin Irie, Christine Juergens, Masako Yamaji, Satoshi Tamai, Masakazu Aizawa, Todd Belanger, William C Gruber, Daniel A Scott & Beate Schmoele-Thoma
Pages: 1850-1858
Published online: 28 Apr 2014
AbstractforImmunogenicity and safety of 13-valent pneumococcal conjugate vaccine when administered to healthy Japanese adults aged ≥50 years | Full Text | References | PDF (1.9 MB) | Supplemental
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Article
Immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine as a booster dose in 12- to 18-month-old children primed with 3 doses of 7-valent pneumococcal conjugate vaccine
Usa Thisyakorn, Kulkanya Chokephaibulkit, Pope Kosalaraksa, Suwat Benjaponpitak, Chitsanu Pancharoen & Sunate Chuenkitmongkol
Pages: 1859-1865
Published online: 23 Apr 2014
AbstractforImmunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine as a booster dose in 12- to 18-month-old children primed with 3 doses of 7-valent pneumococcal conjugate vaccine | Full Text | References | PDF (530.1 KB) | Supplemental
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Article
Changing trends in serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae causing invasive diseases in Central Thailand, 2009–2012
Wanatpreeya Phongsamart, Somporn Srifeungfung, Tanittha Chatsuwan, Pongpun Nunthapisud, Vipa Treerauthaweeraphong, Pimpha Rungnobhakhun, Sirintip Sricharoenchai & Kulkanya Chokephaibulkit
Pages: 1866-1873
Published online: 23 Apr 2014
AbstractforChanging trends in serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae causing invasive diseases in Central Thailand, 2009–2012 | Full Text | References | PDF (960.7 KB)
  • 1918 Views
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Article
Pentavalent replicon vaccines against botulinum neurotoxins and tetanus toxin using DNA-based Semliki Forest virus replicon vectors
YunZhou Yu, Si Liu, Yao Ma, Zheng-Wei Gong, Shuang Wang & Zhi-Wei Sun
Pages: 1874-1879
Published online: 01 May 2014
AbstractforPentavalent replicon vaccines against botulinum neurotoxins and tetanus toxin using DNA-based Semliki Forest virus replicon vectors | Full Text | References | PDF (357 KB)
  • 885 Views
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Article
Immunomodulatory effects of recombinant BCG expressing MSP-1C of Plasmodium falciparum on LPS- or LPS+IFN-γ-stimulated J774A.1 cells
Dhaniah Mohamad, Rapeah Suppian & Norazmi Mohd Nor
Pages: 1880-1886
Published online: 24 Apr 2014
AbstractforImmunomodulatory effects of recombinant BCG expressing MSP-1C of Plasmodium falciparum on LPS- or LPS+IFN-γ-stimulated J774A.1 cells | Full Text | References | PDF (3.2 MB)
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Review

Review Article
Laser vaccine adjuvants
History, progress, and potential
Satoshi Kashiwagi, Timothy Brauns, Jeffrey Gelfand & Mark C Poznansky
Pages: 1892-1907
Published online: 29 Apr 2014
AbstractforLaser vaccine adjuvants | Full Text | References | PDF (2.6 MB)
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Commentary

Engineered PRINT® nanoparticles for controlled delivery of antigens and immunostimulants
Anton Beletskii, Ashley Galloway, Shyam Rele, Michele Stone & Frank Malinoski
Pages: 1908-1913
Published online: 22 Apr 2014
AbstractforEngineered PRINT® nanoparticles for controlled delivery of antigens and immunostimulants | Full Text | References | PDF (1.5 MB)
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Short Report

Brief Report
Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate
Elena Curti, Christopher A Seid, Elissa Hudspeth, Lori Center, Wanderson Rezende, Jeroen Pollet, Cliff Kwityn, Molly Hammond, Rise K Matsunami, David A Engler, Peter J Hotez & Maria Elena Bottazzi
Pages: 1914-1925
Published online: 30 Apr 2014
AbstractforOptimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate | Full Text | References | PDF (1.1 MB)
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Book Review

Review of Gene Vaccines book
Kenneth E Ugen
Page: 1926
Published online: 23 Apr 2014
CitationforReview of Gene Vaccines book | Full Text | PDF (550.8 KB)
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Commentary

Hepatitis C vaccine
Need of the hour
Ramesh Verma, Pardeep Khanna & Suraj Chawla
Pages: 1927-1929
Published online: 08 May 2014
AbstractforHepatitis C vaccine | Full Text | References | PDF (593.4 KB)
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Research Paper

Article
Annual influenza vaccination
Uptake, barriers, and enablers among student health care providers at the University of Notre Dame Australia, Fremantle
David A Kelly, David J Macey & Donna B Mak
Pages: 1930-1934
Published online: 08 May 2014
AbstractforAnnual influenza vaccination | Full Text | References | PDF (699.1 KB)
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Review

Review Article
Fast vaccine design and development based on correlates of protection (COPs): Influenza as a trendsetter
Cécile van Els, Siri Mjaaland, Lisbeth Næss, Julia Sarkadi, Eva Gonczol, Karen Smith Korsholm, Jon Hansen, Jørgen de Jonge, Gideon Kersten, Jennifer Warner, Amanda Semper, Corine Kruiswijk & Fredrik Oftung
Pages: 1935-1948
Published online: 24 Apr 2014
AbstractforFast vaccine design and development based on correlates of protection (COPs): Influenza as a trendsetter | Full Text | References | PDF (1.4 MB)
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Research Paper

Article
Optimal designs of an HA-based DNA vaccine against H7 subtype influenza viruses
Lu Zhang, Na Jia, Jun Li, Yaping Han, Wuchun Cao, Shixia Wang, Zuhu Huang & Shan Lu
Pages: 1949-1958
Published online: 30 Apr 2014
AbstractforOptimal designs of an HA-based DNA vaccine against H7 subtype influenza viruses | Full Text | References | PDF (1.6 MB)
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Article
A phase 1, open-label safety and immunogenicity study of an AS03-adjuvanted trivalent inactivated influenza vaccine in children aged 6 to 35 months
Alfonso Carmona Martinez, Ignacio Salamanca de la Cueva, Philippe Boutet, Carline Vanden Abeele, Igor Smolenov & Jeanne-Marie Devaster
Pages: 1959-1968
Published online: 30 Apr 2014
AbstractforA phase 1, open-label safety and immunogenicity study of an AS03-adjuvanted trivalent inactivated influenza vaccine in children aged 6 to 35 months | Full Text | References | PDF (486.2 KB) | Supplemental
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Case Report

Case Report
Acute disseminated encephalomyelitis with severe neurological outcomes following virosomal seasonal influenza vaccine
Cristiano Alicino, Maria Teresa Infante, Ilaria Gandoglia, Nadia Miolo, Gian Luigi Mancardi, Simona Zappettini, Elisabetta Capello, Andrea Orsi, Tiziano Tamburini & Marina Grandis
Pages: 1969-1973
Published online: 01 May 2014
AbstractforAcute disseminated encephalomyelitis with severe neurological outcomes following virosomal seasonal influenza vaccine | Full Text | References | PDF (283.8 KB)
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Review

Review Article
Effect of race/ethnicity on participation in HIV vaccine trials and comparison to other trials of biomedical prevention
Shayesta Dhalla & Gary Poole
Pages: 1974-1984
Published online: 01 May 2014
AbstractforEffect of race/ethnicity on participation in HIV vaccine trials and comparison to other trials of biomedical prevention | Full Text | References | PDF (715.9 KB)
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Research Paper

Article
The role of follicular helper T cells and the germinal center in HIV-1 gp120 DNA prime and gp120 protein boost vaccination
Kristin Hollister, Yuxin Chen, Shixia Wang, Hao Wu, Arpita Mondal, Ninah Clegg, Shan Lu & Alexander Dent
Pages: 1985-1992
Published online: 29 Apr 2014
AbstractforThe role of follicular helper T cells and the germinal center in HIV-1 gp120 DNA prime and gp120 protein boost vaccination | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
A phase 2 randomized controlled trial of a multicomponent meningococcal serogroup B vaccine (I)
Effects of prophylactic paracetamol on immunogenicity and reactogenicity of routine infant vaccines and 4CMenB
Roman Prymula, Susanna Esposito, Gian Vincenzo Zuccotti, Fang Xie, Daniela Toneatto, Igor Kohl & Peter M Dull
Pages: 1993-2004
Published online: 24 Apr 2014
AbstractforA phase 2 randomized controlled trial of a multicomponent meningococcal serogroup B vaccine (I) | Full Text | References | PDF (830.5 KB) | Supplemental
  • 4375 Views
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Article
A phase II randomized controlled trial of a multicomponent meningococcal serogroup B vaccine, 4CMenB, in infants (II)
Effects of variations of the OMV and protein content on immunogenicity and reactogenicity
Susanna Esposito, Roman Prymula, Gian Vincenzo Zuccotti, Fang Xie, Michelangelo Barone, Peter M Dull & Daniela Toneatto
Pages: 2005-2014
Published online: 11 Jul 2014
AbstractforA phase II randomized controlled trial of a multicomponent meningococcal serogroup B vaccine, 4CMenB, in infants (II) | Full Text | References | PDF (1.5 MB) | Supplemental
  • 1976 Views
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Article
Oral delivery of Brucella spp. recombinant protein U-Omp16 abrogates the IgE-mediated milk allergy
Paola Lorena Smaldini, Andrés Esteban Ibañez, Carlos Alberto Fossati, Juliana Cassataro & Guillermo Horacio Docena
Pages: 2015-2023
Published online: 01 May 2014
AbstractforOral delivery of Brucella spp. recombinant protein U-Omp16 abrogates the IgE-mediated milk allergy | Full Text | References | PDF (3.3 MB)
  • 881 Views
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Article
Vaccination induced changes in pro-inflammatory cytokine levels as an early putative biomarker for cognitive improvement in a transgenic mouse model for Alzheimer disease
Xiaoyang Lin, Ge Bai, Linda Lin, Hengyi Wu, Jianfeng Cai, Kenneth E Ugen & Chuanhai Cao
Pages: 2024-2031
Published online: 21 Apr 2014
AbstractforVaccination induced changes in pro-inflammatory cytokine levels as an early putative biomarker for cognitive improvement in a transgenic mouse model for Alzheimer disease | Full Text | References | PDF (1.4 MB)
  • 1074 Views
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Article
Public health impact of accelerated immunization against rotavirus infection among children aged less than 6 months in the United States
Derek Weycker, Mark Andrew Atwood, Baudouin Standaert & Girishanthy Krishnarajah
Pages: 2032-2038
Published online: 29 Apr 2014
AbstractforPublic health impact of accelerated immunization against rotavirus infection among children aged less than 6 months in the United States | Full Text | References | PDF (1.2 MB) | Supplemental
  • 765 Views
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Article
Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo
Suvi Lappalainen, Ana Ruth Pastor, Kirsi Tamminen, Vanessa López-Guerrero, Fernando Esquivel-Guadarrama, Laura A Palomares, Timo Vesikari & Vesna Blazevic
Pages: 2039-2047
Published online: 29 Apr 2014
AbstractforImmune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo | Full Text | References | PDF (1.3 MB)
  • 1884 Views
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Review

Review Article
Cost-effectiveness of vaccination against herpes zoster
Pieter T de Boer, Jan C Wilschut & Maarten J Postma
Pages: 2048-2061
Published online: 12 Aug 2014
AbstractforCost-effectiveness of vaccination against herpes zoster | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1966 Views
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Letter

Letter
Study on the effectiveness and impact of pentavalent vaccination program in India and other south Asian countries
Sreelakshmi Sreedhar, Anil Antony & Neethu Poulose
Pages: 2062-2065
Published online: 01 May 2014
AbstractforStudy on the effectiveness and impact of pentavalent vaccination program in India and other south Asian countries | Full Text | References | PDF (634.1 KB)
  • 2929 Views
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Research Paper

Article
Relationship of immunogenicity to protective potency in acellular pertussis vaccines
Dorothy Xing, Catpagavalli Asokanathan, Ying Hua Xu, Barbara Bolgiano, Alex Douglas-Bardsley, Shumin Zhang, Junzhi Wang & Michael Corbel
Pages: 2066-2073
Published online: 30 Apr 2014
AbstractforRelationship of immunogenicity to protective potency in acellular pertussis vaccines | Full Text | References | PDF (1.2 MB)
  • 1081 Views
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Article
Investigation in a murine model of possible mechanisms of enhanced local reactions to post-primary diphtheria-tetanus toxoid boosters in recipients of acellular pertussis-diphtheria-tetanus vaccine
Masaki Ochiai, Yoshinobu Horiuchi, Chun-Ting Yuen, Catpagavalli Asokanathan, Akihiko Yamamoto, Kenji Okada, Michiyo Kataoka, Kevin Markey, Michael Corbel & Dorothy Xing
Pages: 2074-2080
Published online: 01 May 2014
AbstractforInvestigation in a murine model of possible mechanisms of enhanced local reactions to post-primary diphtheria-tetanus toxoid boosters in recipients of acellular pertussis-diphtheria-tetanus vaccine | Full Text | References | PDF (818.2 KB)
  • 645 Views
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Case Report

Case Report
Probable disseminated BCG infection in a 10-month-old child after BCG vaccination
Ahmed Zaïem, Senda El Ferjani, Ghozlane Lakhoua, Rym Sahnoun, Talel Badri, Sarrah Kastalli, Riadh Daghfous, Mohamed Lakhal & Sihem El Aidli
Pages: 2081-2082
Published online: 01 May 2014
AbstractforProbable disseminated BCG infection in a 10-month-old child after BCG vaccination | Full Text | References | PDF (611.7 KB)
  • 723 Views
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Review

Review Article
Premature B-cell senescence as a consequence of chronic immune activation
Implications for vaccination of immune compromised individuals
Paolo Palma, Stefano Rinaldi, Nicola Cotugno, Veronica Santilli, Savita Pahwa, Paolo Rossi & Alberto Cagigi
Pages: 2083-2088
Published online: 23 Apr 2014
AbstractforPremature B-cell senescence as a consequence of chronic immune activation | Full Text | References | PDF (745.5 KB)
  • 1323 Views
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Research Paper

Article
Immunogenicity and safety of a pediatric dose of a virosomal hepatitis A vaccine in healthy children in India
Results from a phase IV, open, randomized, controlled, multicenter, non-inferiority study
Hemat Jain, Vandana Kumavat, Tejinder Singh, Amanda Versteilen & Michal Sarnecki
Pages: 2089-2097
Published online: 07 May 2014
AbstractforImmunogenicity and safety of a pediatric dose of a virosomal hepatitis A vaccine in healthy children in India | Full Text | References | PDF (1.3 MB)
  • 800 Views
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Article
Influenza vaccine hesitancy in a low-income community in central New York State
Manika Suryadevara, Cynthia A Bonville, Paula F Rosenbaum & Joseph B Domachowske
Pages: 2098-2103
Published online: 29 Apr 2014
AbstractforInfluenza vaccine hesitancy in a low-income community in central New York State | Full Text | References | PDF (645.9 KB)
  • 2009 Views
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Commentary

NIC24 Introduction
Martin J Guppy
Pages: 2104-2105
Published online: 11 Jul 2014
CitationforNIC24 Introduction | Full Text | PDF (568.8 KB)
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Review

Review Article
HPV vaccination in boys and men
Margaret Stanley
Pages: 2106-2108
Published online: 08 May 2014
AbstractforHPV vaccination in boys and men | Full Text | References | PDF (614.2 KB)
  • 2085 Views
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REVIEW

Review Article
HPV vaccination in boys and men
Margaret Stanley
Pages: 2109-2111
Published online: 08 May 2014
AbstractforHPV vaccination in boys and men | Full Text | References | PDF (616.4 KB)
  • 11487 Views
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Review

Review Article
Mucosal Immunity and acute viral gastroenteritis
The example rotavirus
Markus A Rose
Pages: 2112-2114
Published online: 11 Jul 2014
AbstractforMucosal Immunity and acute viral gastroenteritis | Full Text | References | PDF (605.6 KB)
  • 914 Views
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Review Article
Mucosal immunization in perspective
Pediatric influenza vaccines
Markus A Rose
Pages: 2115-2117
Published online: 11 Jul 2014
AbstractforMucosal immunization in perspective | Full Text | References | PDF (609 KB)
  • 1117 Views
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Review Article
Antenatal immunization
Concepts and challenges
Chrissie Jones & Paul Heath
Pages: 2118-2122
Published online: 11 Jul 2014
AbstractforAntenatal immunization | Full Text | References | PDF (1.4 MB)
  • 1848 Views
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Review Article
Active and passive immunization for cancer
David Baxter
Pages: 2123-2129
Published online: 11 Jul 2014
AbstractforActive and passive immunization for cancer | Full Text | References | PDF (650.2 KB)
  • 4717 Views
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Review Article
Health literacy
Ways to maximise the impact and effectiveness of vaccination information
Gillian Rowlands
Pages: 2130-2135
Published online: 11 Jul 2014
AbstractforHealth literacy | Full Text | References | PDF (679.3 KB)
  • 5059 Views
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REVIEW

Review
The polio endgame
Philip Minor
Pages: i-iii
Published online: 21 Jan 2015
AbstractforThe polio endgame | Full Text | References | PDF (127.7 KB)
  • 4803 Views
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