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Volume 4, Issue 4

mAbs

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mAbs, Volume 4, Issue 4 (2012)

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mAbs, Volume 4, Issue 4 (2012)

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Editorial

Marketing approval of mogamulizumab

A triumph for glyco-engineering

Alain Beck & Janice M. Reichert

Pages: 419-425

Published online: 01 Jul 2012

AbstractforMarketing approval of mogamulizumab | Full Text | References | PDF (1.2 MB)

4132 Views
179 CrossRef citations
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Open Access

Meeting Report

1st French-Israeli International Conference on B Cells and therapeutic antibodies

October 23–25, 2011 Jerusalem, Israel

Claude-Agnès Reynaud, Sandrine Moutel, Marie-Caroline Dieu-Nosjean, Reuven Laskov & Jean-Luc Teillaud

Pages: 426-433

Published online: 01 Jul 2012

First Page Previewfor1st French-Israeli International Conference on B Cells and therapeutic antibodies | Full Text | References | PDF (254.5 KB)

539 Views
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Open Access

Meeting Report

7th Cancer Scientific Forum of the Cancéropôle Lyon Auvergne Rhône-Alpes

March 20–21, 2012, Lyon, France

Petrus J. Pauwels, Charles Dumontet, Janice M. Reichert, Alain Beck, Liliane Goetsch, Nathalie Corvaïa, Christian Klein, Bertrand Coiffier & Beverly A. Teicher

Pages: 434-444

Published online: 01 Jul 2012

Abstractfor7th Cancer Scientific Forum of the Cancéropôle Lyon Auvergne Rhône-Alpes | Full Text | References | PDF (562.8 KB)

748 Views
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Open Access

Review

Review Article

Molecular engineering of antibodies for therapeutic and diagnostic purposes

Frédéric Ducancel & Bruno H. Muller

Pages: 445-457

Published online: 01 Jul 2012

AbstractforMolecular engineering of antibodies for therapeutic and diagnostic purposes | Full Text | References | PDF (352.6 KB)

3615 Views
78 CrossRef citations
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Free Access

Review Article

Brentuximab vedotin

Niels W. C.J. van de Donk & Eugen Dhimolea

Pages: 458-465

Published online: 01 Jul 2012

AbstractforBrentuximab vedotin | Full Text | References | PDF (1.4 MB)

4482 Views
104 CrossRef citations
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Free Access

Report

Article

Pharmacokinetics of engineered human monomeric and dimeric CH2 domains

Kurt R. Gehlsen, Rui Gong, Dave Bramhill, David A. Wiersma, Shaun A. Kirkpatrick, Yangping Wang, Yang Feng & Dimiter S. Dimitrov

Pages: 466-474

Published online: 01 Jul 2012

AbstractforPharmacokinetics of engineered human monomeric and dimeric CH2 domains | Full Text | References | PDF (1.7 MB)

1383 Views
20 CrossRef citations
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Open Access

Article

Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans

Marcella Yu, Darren Brown, Chae Reed, Shan Chung, Jeff Lutman, Eric Stefanich, Anne Wong, Jean-Philippe Stephan & Robert Bayer

Pages: 475-487

Published online: 01 Jul 2012

AbstractforProduction, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans | Full Text | References | PDF (1.5 MB)

5983 Views
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Free Access

Article

Expression and biological characterization of an anti-CD20 biosimilar candidate antibody

A case study

Denise Dorvignit, Julio L. Palacios, Maylin Merino, Tays Hernández, Katya Sosa, Angel Casacó, Alejandro López-Requena & Cristina Mateo de Acosta

Pages: 488-496

Published online: 01 Jul 2012

AbstractforExpression and biological characterization of an anti-CD20 biosimilar candidate antibody | Full Text | References | PDF (897.6 KB)

2005 Views
14 CrossRef citations
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Article

Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain

Daniel Schlatter, Simon Brack, David W. Banner, Sarah Batey, Jörg Benz, Julian Bertschinger, Walter Huber, Catherine Joseph, Arne C. Rufer, Anita van der Klooster, Martin Weber, Dragan Grabulovski & Michael Hennig

Pages: 497-508

Published online: 01 Jul 2012

AbstractforGeneration, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain | Full Text | References | PDF (2.7 MB) | Supplemental

1339 Views
32 CrossRef citations
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Open Access

Article

Increased serum clearance of oligomannose species present on a human IgG1 molecule

Leslie Alessandri, David Ouellette, Aima Acquah, Mathew Rieser, David LeBlond, Mary Saltarelli, Czeslaw Radziejewski, Taro Fujimori & Ivan Correia

Pages: 509-520

Published online: 01 Jul 2012

AbstractforIncreased serum clearance of oligomannose species present on a human IgG1 molecule | Full Text | References | PDF (2 MB) | Supplemental

2828 Views
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Open Access

Article

A high throughput capillary electrophoresis method to obtain pharmacokinetics and quality attributes of a therapeutic molecule in circulation

Reema Piparia, David Ouellette, W. Blaine Stine, Christine Grinnell, Edit Tarcsa, Czeslaw Radziejewski & Ivan Correia

Pages: 521-531

Published online: 01 Jul 2012

AbstractforA high throughput capillary electrophoresis method to obtain pharmacokinetics and quality attributes of a therapeutic molecule in circulation | Full Text | References | PDF (3 MB)

1076 Views
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Article

Correlation of ADCC activity with cytokine release induced by the stably expressed, glyco-engineered humanized Lewis Y-specific monoclonal antibody MB314

Ralf Kircheis, Nicole Halanek, Iris Koller, Wolfgang Jost, Manfred Schuster, Gilbert Gorr, Klaus Hajszan & Andreas Nechansky

Pages: 532-541

Published online: 01 Jul 2012

AbstractforCorrelation of ADCC activity with cytokine release induced by the stably expressed, glyco-engineered humanized Lewis Y-specific monoclonal antibody MB314 | Full Text | References | PDF (1.8 MB)

2350 Views
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Article

An efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification

Pablo H. Sotelo, Noberto Collazo, Roberto Zuñiga, Matías Gutiérrez-González, Diego Catalán, Carolina Hager Ribeiro, Juan Carlos Aguillón & María Carmen Molina

Pages: 542-550

Published online: 01 Jul 2012

AbstractforAn efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification | Full Text | References | PDF (638.6 KB)

1338 Views
8 CrossRef citations
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Free Access

Editor's Corner

Editorial

2012 Upcoming Meetings

Janice M. Reichert

Pages: 551-552

Published online: 01 Jul 2012

Abstractfor2012 Upcoming Meetings | Full Text | PDF (155.1 KB)

363 Views
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Open Access

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