OncoImmunology, Volume 4, Issue 11 (2015)

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OncoImmunology, Volume 4, Issue 11 (2015)

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Author's View

Opinion
TLR activation and ionizing radiation induce strong immune responses against multiple tumor entities
Sebastian Schölch, Conrad Rauber, Jürgen Weitz, Moritz Koch & Peter E Huber
Article: e1042201
Published online: 14 Sep 2015
AbstractforTLR activation and ionizing radiation induce strong immune responses against multiple tumor entities | Full Text | References | PDF (156.1 KB)
  • 1057 Views
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Opinion
Natural killer cell mediated immunosurveillance of pediatric neuroblastoma
Michaela Semeraro, Sylvie Rusakiewicz, Laurence Zitvogel & Guido Kroemer
Article: e1042202
Published online: 14 Sep 2015
AbstractforNatural killer cell mediated immunosurveillance of pediatric neuroblastoma | Full Text | References | PDF (172.6 KB)
  • 1002 Views
  • 27 CrossRef citations
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Opinion
Toward a rational design of combination therapy in cancer
Marie-Agnès Doucey & Ioannis Xenarios
Article: e1046674
Published online: 14 Sep 2015
AbstractforToward a rational design of combination therapy in cancer | Full Text | References | PDF (163.6 KB)
  • 881 Views
  • 1 CrossRef citations
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Open Access
Opinion
CD73: A potential biomarker for anti-PD-1 therapy
Paul A Beavis, Clare Y Slaney, Nicole Milenkovski, Melissa A Henderson, Sherene Loi, John Stagg, Michael H Kershaw & Phillip K Darcy
Article: e1046675
Published online: 14 Sep 2015
AbstractforCD73: A potential biomarker for anti-PD-1 therapy | Full Text | References | PDF (248.6 KB)
  • 2310 Views
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Opinion
Restoring inflammatory balance as a potential preventive strategy for inflammation induced cancer
Simona Hefetz-Sela, Ilan Stein & Eli Pikarsky
Article: e1039764
Published online: 14 Sep 2015
AbstractforRestoring inflammatory balance as a potential preventive strategy for inflammation induced cancer | Full Text | References | PDF (143.1 KB)
  • 411 Views
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Article
β3-adrenoreceptor and tumor microenvironment: a new hub
Paola Chiarugi & Luca Filippi
Article: e1026532
Published online: 14 Sep 2015
Abstractforβ3-adrenoreceptor and tumor microenvironment: a new hub | Full Text | References | PDF (290.8 KB)
  • 526 Views
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Original Research

Article
Characterization of T cell repertoire of blood, tumor, and ascites in ovarian cancer patients using next generation sequencing
Miran Jang, Poh-Yin Yew, Kosei Hasegawa, Yuji Ikeda, Keiichi Fujiwara, Gini F Fleming, Yusuke Nakamura & Jae-Hyun Park
Article: e1030561
Published online: 20 Aug 2015
AbstractforCharacterization of T cell repertoire of blood, tumor, and ascites in ovarian cancer patients using next generation sequencing | Full Text | References | PDF (1.3 MB) | Supplemental
  • 3517 Views
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Open Access
Article
An optimized peptide vaccine strategy capable of inducing multivalent CD8+ T cell responses with potent antitumor effects
Hyun-Il Cho, Soo-Hyun Jung, Hyun-Jung Sohn, Esteban Celis & Tai-Gyu Kim
Article: e1043504
Published online: 14 Sep 2015
AbstractforAn optimized peptide vaccine strategy capable of inducing multivalent CD8+ T cell responses with potent antitumor effects | Full Text | References | PDF (726.4 KB) | Supplemental
  • 2289 Views
  • 24 CrossRef citations
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Open Access
Article
COX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells
Ze-Lei Li, Shu-Biao Ye, Li-Yin OuYang, Han Zhang, Yu-Shan Chen, Jia He, Qiu-Yan Chen, Chao-Nan Qian, Xiao-Shi Zhang, Jun Cui, Yi-Xin Zeng & Jiang Li
Article: e1044712
Published online: 14 Sep 2015
AbstractforCOX-2 promotes metastasis in nasopharyngeal carcinoma by mediating interactions between cancer cells and myeloid-derived suppressor cells | Full Text | References | PDF (1.4 MB) | Supplemental
  • 1821 Views
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Article
Spatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/neu by human dendritic cells
Renato B Baleeiro, René Rietscher, Andrea Diedrich, Justyna A Czaplewska, Claus-Michael Lehr, Regina Scherließ, Andrea Hanefeld, Michael Gottschaldt & Peter Walden
Article: e1047585
Published online: 14 Sep 2015
AbstractforSpatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/neu by human dendritic cells | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1012 Views
  • 9 CrossRef citations
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Article
Immunomodulatory effect of peritumorally administered interferon-beta on melanoma through tumor-associated macrophages
Aya Kakizaki, Taku Fujimura, Sadanori Furudate, Yumi Kambayashi, Takeshi Yamauchi, Hideo Yagita & Setsuya Aiba
Article: e1047584
Published online: 14 Sep 2015
AbstractforImmunomodulatory effect of peritumorally administered interferon-beta on melanoma through tumor-associated macrophages | Full Text | References | PDF (994.1 KB)
  • 2130 Views
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Open Access
Article
Chimeric antigen receptor T cells targeting HERV-K inhibit breast cancer and its metastasis through downregulation of Ras
Fuling Zhou, Janani Krishnamurthy, Yongchang Wei, Ming Li, Kelly Hunt, Gary L Johanning, Laurence JN Cooper & Feng Wang-Johanning
Article: e1047582
Published online: 14 Sep 2015
AbstractforChimeric antigen receptor T cells targeting HERV-K inhibit breast cancer and its metastasis through downregulation of Ras | Full Text | References | PDF (2.3 MB) | Supplemental
  • 3182 Views
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Article
Histamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas
Brian Ahn, Gary Kohanbash, Takayuki Ohkuri, Akemi Kosaka, Xiaowei Chen, Maki Ikeura, Timothy C Wang & Hideho Okada
Article: e1047581
Published online: 14 Sep 2015
AbstractforHistamine deficiency promotes accumulation of immunosuppressive immature myeloid cells and growth of murine gliomas | Full Text | References | PDF (510.2 KB)
  • 1062 Views
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Article
Anergic bone marrow Vγ9Vδ2 T cells as early and long-lasting markers of PD-1-targetable microenvironment-induced immune suppression in human myeloma
Barbara Castella, Myriam Foglietta, Patrizia Sciancalepore, Micol Rigoni, Marta Coscia, Valentina Griggio, Candida Vitale, Riccardo Ferracini, Elona Saraci, Paola Omedé, Chiara Riganti, Antonio Palumbo, Mario Boccadoro & Massimo Massaia
Article: e1047580
Published online: 14 Sep 2015
AbstractforAnergic bone marrow Vγ9Vδ2 T cells as early and long-lasting markers of PD-1-targetable microenvironment-induced immune suppression in human myeloma | Full Text | References | PDF (694.8 KB) | Supplemental
  • 1879 Views
  • 53 CrossRef citations
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Open Access
Article
In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity
Michaela Prchal-Murphy, Agnieszka Witalisz-Siepracka, Karoline T Bednarik, Eva Maria Putz, Dagmar Gotthardt, Katrin Meissl, Veronika Sexl, Mathias Müller & Birgit Strobl
Article: e1047579
Published online: 14 Sep 2015
AbstractforIn vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity | Full Text | References | PDF (932.5 KB) | Supplemental
  • 2207 Views
  • 26 CrossRef citations
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Open Access
Article
Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation
Colin de Haar, Maud Plantinga, Nina JG Blokland, Niek P van Til, Thijs WH Flinsenberg, Viggo F Van Tendeloo, Evelien L Smits, Louis Boon, Lotte Spel, Marianne Boes, Jaap Jan Boelens & Stefan Nierkens
Article: e1023973
Published online: 14 Sep 2015
AbstractforGeneration of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation | Full Text | References | PDF (862.7 KB) | Supplemental
  • 1188 Views
  • 21 CrossRef citations
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Article
Tolerance and efficacy of autologous or donor-derived T cells expressing CD19 chimeric antigen receptors in adult B-ALL with extramedullary leukemia
Hanren Dai, Wenying Zhang, Xiaolei Li, Qingwang Han, Yelei Guo, Yajing Zhang, Yao Wang, Chunmeng Wang, Fengxia Shi, Yan Zhang, Meixia Chen, Kaichao Feng, Quanshun Wang, Hongli Zhu, Xiaobing Fu, Suxia Li & Weidong Han
Article: e1027469
Published online: 14 Sep 2015
AbstractforTolerance and efficacy of autologous or donor-derived T cells expressing CD19 chimeric antigen receptors in adult B-ALL with extramedullary leukemia | Full Text | References | PDF (985.4 KB) | Supplemental
  • 4956 Views
  • 128 CrossRef citations
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Open Access
Article
Increased sMICA and TGFβ1 levels in HNSCC patients impair NKG2D-dependent functionality of activated NK cells
Stephan Klöß, Nicole Chambron, Tanja Gardlowski, Lubomir Arseniev, Joachim Koch, Ruth Esser, Wolfgang Glienke, Oliver Seitz & Ulrike Köhl
Article: e1055993
Published online: 14 Sep 2015
AbstractforIncreased sMICA and TGFβ1 levels in HNSCC patients impair NKG2D-dependent functionality of activated NK cells | Full Text | References | PDF (19.7 MB) | Supplemental
  • 1100 Views
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Article
Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma
Panagiotis Karagiannis, Federica Villanova, Debra H Josephs, Isabel Correa, Mieke Van Hemelrijck, Carl Hobbs, Louise Saul, Isioma U Egbuniwe, Isabella Tosi, Kristina M Ilieva, Emma Kent, Eduardo Calonje, Mark Harries, Ian Fentiman, Joyce Taylor-Papadimitriou, Joy Burchell, James F Spicer, Katie E Lacy, Frank O Nestle & Sophia N Karagiannis
Article: e1032492
Published online: 14 Sep 2015
AbstractforElevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma | Full Text | References | PDF (1 MB) | Supplemental
  • 2302 Views
  • 43 CrossRef citations
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Open Access
Article
A systematic evaluation of abscopal responses following radiotherapy in patients with metastatic melanoma treated with ipilimumab
Ravi A Chandra, Tyler J Wilhite, Tracy A Balboni, Brian M Alexander, Alexander Spektor, Patrick A Ott, Andrea K Ng, F Stephen Hodi & Jonathan D Schoenfeld
Article: e1046028
Published online: 14 Sep 2015
AbstractforA systematic evaluation of abscopal responses following radiotherapy in patients with metastatic melanoma treated with ipilimumab | Full Text | References | PDF (245.9 KB) | Supplemental
  • 2706 Views
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Review

Review
Trial Watch: Adoptive cell transfer for oncological indications
Fernando Aranda, Aitziber Buqué, Norma Bloy, Francesca Castoldi, Alexander Eggermont, Isabelle Cremer, Wolf Hervé Fridman, Jitka Fucikova, Jérôme Galon, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e1046673
Published online: 14 Sep 2015
AbstractforTrial Watch: Adoptive cell transfer for oncological indications | Full Text | References | PDF (167.1 KB)
  • 2736 Views
  • 27 CrossRef citations
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