Virulence, Volume 11, Issue 1 (2020)

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Virulence, Volume 11, Issue 1 (2020)

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Research Article

Article
Wza gene knockout decreases Acinetobacter baumannii virulence and affects Wzy-dependent capsular polysaccharide synthesis
Tianshui Niu, Lihua Guo, Qixia Luo, Kai Zhou, Wei Yu, Yunbo Chen, Chen Huang & Yonghong Xiao
Pages: 1-13
Published online: 27 Dec 2019
AbstractforWza gene knockout decreases Acinetobacter baumannii virulence and affects Wzy-dependent capsular polysaccharide synthesis | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
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Review Article

Review Article
Mini review: Prevention of mother–child transmission of HIV: 25 years of continuous progress toward the eradication of pediatric AIDS?
Stéphane Blanche
Pages: 14-22
Published online: 29 Dec 2019
AbstractforMini review: Prevention of mother–child transmission of HIV: 25 years of continuous progress toward the eradication of pediatric AIDS? | Full Text | References | PDF (1.7 MB) | EPUB
  • 3087 Views
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Research Article

Article
Complete genome analysis of Vibrio mimicus strain SCCF01, a highly virulent isolate from the freshwater catfish
Zehui Yu, Erlong Wang, Yi Geng, Kaiyu Wang, Defang Chen, Xiaoli Huang, Ping Ouyang, Zhicai Zuo, Chao Huang, Jing Fang, Lizi Yin, Hongrui Guo & Zhijun Zhong
Pages: 23-31
Published online: 28 Dec 2019
AbstractforComplete genome analysis of Vibrio mimicus strain SCCF01, a highly virulent isolate from the freshwater catfish | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 2574 Views
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Brief Report

Brief Report
Exosomes cloak the virion to transmit Enterovirus 71 non-lytically
Jiaqi Gu, Jing Wu, Daihua Fang, Yang Qiu, Xinran Zou, Xiaonan Jia, Yiqian Yin, Li Shen & Lingxiang Mao
Pages: 32-38
Published online: 28 Dec 2019
AbstractforExosomes cloak the virion to transmit Enterovirus 71 non-lytically | Full Text | References | PDF (2.4 MB) | EPUB
  • 3227 Views
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Research Article

Article
Metformin promotes innate immunity through a conserved PMK-1/p38 MAPK pathway
Yi Xiao, Fang Liu, Sanhua Li, Nian Jiang, Changyan Yu, Xinting Zhu, Ying Qin, Jing Hui, Lingjie Meng, Changwei Song, Xiao-Fei Li & Yun Liu
Pages: 39-48
Published online: 28 Dec 2019
AbstractforMetformin promotes innate immunity through a conserved PMK-1/p38 MAPK pathway | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 5259 Views
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Open Access
Article
Harnessing efficient multiplex PCR methods to detect the expanding Tet(X) family of tigecycline resistance genes
Kai Ji, Yongchang Xu, Jian Sun, Man Huang, Xu Jia, Chengjian Jiang & Youjun Feng
Pages: 49-56
Published online: 28 Dec 2019
AbstractforHarnessing efficient multiplex PCR methods to detect the expanding Tet(X) family of tigecycline resistance genes | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 3316 Views
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Open Access
Article
Mechanism of pyocyanin abolishment caused by mvaT mvaU double knockout in Pseudomonas aeruginosa PAO1
Limin Dong, Jing Pang, Xiukun Wang, Youwen Zhang, Guoqing Li, Xinxin Hu, Xinyi Yang, Chung-Dar Lu, Congran Li & Xuefu You
Pages: 57-67
Published online: 28 Dec 2019
AbstractforMechanism of pyocyanin abolishment caused by mvaT mvaU double knockout in Pseudomonas aeruginosa PAO1 | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 3478 Views
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Open Access
Article
Determination of antiviral action of long non-coding RNA loc107051710 during infectious bursal disease virus infection due to enhancement of interferon production
Xuewei Huang, Yigang Xu, Qingyu Lin, Weilong Guo, Dongfang Zhao, Chunmei Wang, Li Wang, Han Zhou, Yanping Jiang, Wen Cui, Xinyuan Qiao, Yijing Li, Guangpeng Ma & Lijie Tang
Pages: 68-79
Published online: 28 Dec 2019
AbstractforDetermination of antiviral action of long non-coding RNA loc107051710 during infectious bursal disease virus infection due to enhancement of interferon production | Full Text | References | PDF (4.1 MB) | EPUB | Supplemental
  • 1867 Views
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Brief Report

Brief Report
Bovine leukemia virus tax gene/Tax protein polymorphism and its relation to Enzootic Bovine Leukosis
Irina M. Zyrianova & Svetlana N. Kovalchuk
Pages: 80-87
Published online: 28 Dec 2019
AbstractforBovine leukemia virus tax gene/Tax protein polymorphism and its relation to Enzootic Bovine Leukosis | Full Text | References | PDF (3.2 MB) | EPUB
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Review Article

Review Article
Setting the stage: The initial immune response to blood-stage parasites
Allison N. Bucşan & Kim C. Williamson
Pages: 88-103
Published online: 03 Jan 2020
AbstractforSetting the stage: The initial immune response to blood-stage parasites | Full Text | References | PDF (2.8 MB) | EPUB
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Brief Report

Brief Report
Twitching motility of Stenotrophomonas maltophilia under iron limitation: In-silico, phenotypic and proteomic approaches
V. Kalidasan & Vasantha Kumari Neela
Pages: 104-112
Published online: 20 Jan 2020
AbstractforTwitching motility of Stenotrophomonas maltophilia under iron limitation: In-silico, phenotypic and proteomic approaches | Full Text | References | PDF (1.6 MB) | EPUB
  • 1867 Views
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Research Article

Article
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes
Jianhong Sun, Wanpo Zhang, Zhongyuan Tan, Caishang Zheng, Yan Tang, Xianliang Ke, Yuan Zhang, Yan Liu, Penghui Li, Qinxue Hu, Hanzhong Wang, Panyong Mao & Zhenhua Zheng
Pages: 113-131
Published online: 20 Jan 2020
AbstractforZika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes | Full Text | References | PDF (6.2 MB) | EPUB
  • 2560 Views
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Open Access
Article
Mutation on lysX from Mycobacterium avium hominissuis impacts the host–pathogen interaction and virulence phenotype
Greana Kirubakar, Hubert Schäfer, Volker Rickerts, Carsten Schwarz & Astrid Lewin
Pages: 132-144
Published online: 29 Jan 2020
AbstractforMutation on lysX from Mycobacterium avium hominissuis impacts the host–pathogen interaction and virulence phenotype | Full Text | References | PDF (2.9 MB) | EPUB | Supplemental
  • 1898 Views
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Open Access
Article
Bacterial membrane vesicles from Acinetobacter baumannii induced by ceftazidime are more virulent than those induced by imipenem
Chun-Hsiang Chiu, Yi-Tzu Lee, Yu-Chun Lin, Shu-Chen Kuo, Ya-Sung Yang, Yung-Chih Wang, Yu-Han Liu, Jung-Chung Lin, Feng-Yee Chang & Te-Li Chen
Pages: 145-158
Published online: 11 Feb 2020
AbstractforBacterial membrane vesicles from Acinetobacter baumannii induced by ceftazidime are more virulent than those induced by imipenem | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1972 Views
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Review Article

Review Article
Balancing in a black box: Potential immunomodulatory roles for TGF-β signaling during blood-stage malaria
Lisa L. Drewry & John T. Harty
Pages: 159-169
Published online: 11 Feb 2020
AbstractforBalancing in a black box: Potential immunomodulatory roles for TGF-β signaling during blood-stage malaria | Full Text | References | PDF (1.3 MB) | EPUB
  • 2521 Views
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Research Article

Article
Distinct host-immune response toward species related intracellular mycobacterial killing: A transcriptomic study
Abhilasha Madhvi, Hridesh Mishra, Novel N. Chegou, Gerard Tromp, Carel J. Van Heerden, R. D. Pietersen, Gina Leisching & Bienyameen Baker
Pages: 170-182
Published online: 13 Feb 2020
AbstractforDistinct host-immune response toward species related intracellular mycobacterial killing: A transcriptomic study | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 2269 Views
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Review Article

Review Article
Orchestrated efforts on host network hijacking: Processes governing virus replication
Xiaofeng Dai, Olivier Hakizimana, Xuanhao Zhang, Aman Chandra Kaushik & Jianying Zhang
Pages: 183-198
Published online: 12 Feb 2020
AbstractforOrchestrated efforts on host network hijacking: Processes governing virus replication | Full Text | References | PDF (5.2 MB) | EPUB
  • 3119 Views
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Review Article
Predictors of outcome in childhood Plasmodium falciparum malaria
Harsita Patel, Claire Dunican & Aubrey J. Cunnington
Pages: 199-221
Published online: 17 Feb 2020
AbstractforPredictors of outcome in childhood Plasmodium falciparum malaria | Full Text | References | PDF (1.6 MB) | EPUB
  • 4435 Views
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Research Article

Article
A M35 family metalloprotease is required for fungal virulence against insects by inactivating host prophenoloxidases and beyond
Antian Huang, Mengting Lu, Erjun Ling, Ping Li & Chengshu Wang
Pages: 222-237
Published online: 21 Feb 2020
AbstractforA M35 family metalloprotease is required for fungal virulence against insects by inactivating host prophenoloxidases and beyond | Full Text | References | PDF (5 MB) | EPUB | Supplemental
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Review Article

Review Article
Immune priming: the secret weapon of the insect world
Gerard Sheehan, Gemma Farrell & Kevin Kavanagh
Pages: 238-246
Published online: 21 Feb 2020
AbstractforImmune priming: the secret weapon of the insect world | Full Text | References | PDF (1.3 MB) | EPUB
  • 8267 Views
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Research Article

Article
A ROD9 island encoded gene in Salmonella Enteritidis plays an important role in acid tolerance response and helps in systemic infection in mice
Susmita Das, Shilpa Ray, Aryashree Arunima, Bikash Sahu & Mrutyunjay Suar
Pages: 247-259
Published online: 01 Mar 2020
AbstractforA ROD9 island encoded gene in Salmonella Enteritidis plays an important role in acid tolerance response and helps in systemic infection in mice | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 1273 Views
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Open Access
Article
MiR-140 inhibits classical swine fever virus replication by targeting Rab25 in swine umbilical vein endothelial cells
Panpan Xu, Shuangkai Jia, Kai Wang, Zhixin Fan, Hongqing Zheng, Jiangman Lv, Yanfen Jiang, Yufeng Hou, Bihao Lou, Hongchao Zhou, Yanming Zhang & Kangkang Guo
Pages: 260-269
Published online: 29 Feb 2020
AbstractforMiR-140 inhibits classical swine fever virus replication by targeting Rab25 in swine umbilical vein endothelial cells | Full Text | References | PDF (2.8 MB) | EPUB
  • 1450 Views
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Open Access
Article
Streptococcus pneumoniae PepO promotes host anti-infection defense via autophagy in a Toll-like receptor 2/4 dependent manner
Zhaoche Shu, Jun Yuan, Hong Wang, Jinghui Zhang, Sijie Li, Hong Zhang, Yusi Liu, Yibing Yin & Xuemei Zhang
Pages: 270-282
Published online: 14 Mar 2020
AbstractforStreptococcus pneumoniae PepO promotes host anti-infection defense via autophagy in a Toll-like receptor 2/4 dependent manner | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
  • 1737 Views
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Open Access
Article
Characterization of Schu S4 aro mutants as live attenuated tularemia vaccine candidates
Aimee L. Cunningham, Barbara J. Mann, Aiping Qin, Araceli E. Santiago, Christen Grassel, Michael Lipsky, Stefanie N. Vogel & Eileen M. Barry
Pages: 283-294
Published online: 02 Apr 2020
AbstractforCharacterization of Schu S4 aro mutants as live attenuated tularemia vaccine candidates | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 1384 Views
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Open Access
Article
RpoS-regulated SEN1538 gene promotes resistance to stress and influences Salmonella enterica serovar enteritidis virulence
Aryashree Arunima, Sunil Kumar Swain, Shilpa Ray, Birendra Kumar Prusty & Mrutyunjay Suar
Pages: 295-314
Published online: 05 Apr 2020
AbstractforRpoS-regulated SEN1538 gene promotes resistance to stress and influences Salmonella enterica serovar enteritidis virulence | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
  • 2374 Views
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Open Access
Article
Direct interaction between RecA and a CheW-like protein is required for surface-associated motility, chemotaxis and the full virulence of Acinetobacter baumannii strain ATCC 17978
Jordi Corral, María Pérez-Varela, Jordi Barbé & Jesús Aranda
Pages: 315-326
Published online: 07 Apr 2020
AbstractforDirect interaction between RecA and a CheW-like protein is required for surface-associated motility, chemotaxis and the full virulence of Acinetobacter baumannii strain ATCC 17978 | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
  • 1984 Views
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Open Access
Article
Molecularly defined extraintestinal pathogenic Escherichia coli status predicts virulence in a murine sepsis model better than does virotype, individual virulence genes, or clonal subset among E. coli ST131 isolates
Irene Merino, Stephen B. Porter, Brian Johnston, Connie Clabots, Paul Thuras, Patricia Ruiz-Garbajosa, Rafael Cantón & James R. Johnson
Pages: 327-336
Published online: 07 Apr 2020
AbstractforMolecularly defined extraintestinal pathogenic Escherichia coli status predicts virulence in a murine sepsis model better than does virotype, individual virulence genes, or clonal subset among E. coli ST131 isolates | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 1838 Views
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Review Article

Review Article
The regulation of hyphae growth in Candida albicans
Hui Chen, Xuedong Zhou, Biao Ren & Lei Cheng
Pages: 337-348
Published online: 10 Apr 2020
AbstractforThe regulation of hyphae growth in Candida albicans | Full Text | References | PDF (2.8 MB) | EPUB
  • 23737 Views
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Research Article

Article
Malate enhances survival of zebrafish against Vibrio alginolyticus infection in the same manner as taurine
Man-Jun Yang, Di Xu, Dai-Xiao Yang, Lu Li, Xuan-Xian Peng, Zhuang-gui Chen & Hui Li
Pages: 349-364
Published online: 21 Apr 2020
AbstractforMalate enhances survival of zebrafish against Vibrio alginolyticus infection in the same manner as taurine | Full Text | References | PDF (6.4 MB) | EPUB | Supplemental
  • 2430 Views
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Article
Subtilisin-like Pr1 proteases marking the evolution of pathogenicity in a wide-spectrum insect-pathogenic fungus
Ben-Jie Gao, Ya-Ni Mou, Sen-Miao Tong, Sheng-Hua Ying & Ming-Guang Feng
Pages: 365-380
Published online: 23 Apr 2020
AbstractforSubtilisin-like Pr1 proteases marking the evolution of pathogenicity in a wide-spectrum insect-pathogenic fungus | Full Text | References | PDF (6.6 MB) | EPUB | Supplemental
  • 2803 Views
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Article
Colonization factor CS30 from enterotoxigenic Escherichia coli binds to sulfatide in human and porcine small intestine
Astrid Von Mentzer, Dani Zalem, Zofia Chrienova & Susann Teneberg
Pages: 381-390
Published online: 14 Apr 2020
AbstractforColonization factor CS30 from enterotoxigenic Escherichia coli binds to sulfatide in human and porcine small intestine | Full Text | References | PDF (3.7 MB) | EPUB
  • 1352 Views
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Review Article

Review Article
Maternal-neonatal listeriosis
Caroline Charlier, Olivier Disson & Marc Lecuit
Pages: 391-397
Published online: 03 May 2020
AbstractforMaternal-neonatal listeriosis | Full Text | References | PDF (1.6 MB) | EPUB
  • 5844 Views
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Editorial

Editorial
Maternal-fetal infections: Why do they matter?
Caroline Charlier & Marc Lecuit
Pages: 398-399
Published online: 03 May 2020
CitationforMaternal-fetal infections: Why do they matter? | Full Text | References | PDF (368.4 KB) | EPUB
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Review Article

Review Article
Mechanisms underlying of antiretroviral drugs in different cellular reservoirs with a focus on macrophages
Stefano Aquaro, Ana Borrajo, Michele Pellegrino & Valentina Svicher
Pages: 400-413
Published online: 06 May 2020
AbstractforMechanisms underlying of antiretroviral drugs in different cellular reservoirs with a focus on macrophages | Full Text | References | PDF (1.3 MB) | EPUB
  • 3015 Views
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Research Article

Article
Host surface ectonucleotidase-CD73 and the opportunistic pathogen, Porphyromonas gingivalis, cross-modulation underlies a new homeostatic mechanism for chronic bacterial survival in human epithelial cells
Jaden S. Lee, Nityananda Chowdhury, JoAnn S. Roberts & Özlem Yilmaz
Pages: 414-429
Published online: 18 May 2020
AbstractforHost surface ectonucleotidase-CD73 and the opportunistic pathogen, Porphyromonas gingivalis, cross-modulation underlies a new homeostatic mechanism for chronic bacterial survival in human epithelial cells | Full Text | References | PDF (3.7 MB) | EPUB | Supplemental
  • 2040 Views
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Article
Toll-like receptor 4 signaling-mediated responses are critically engaged in optimal host protection against highly virulent Mycobacterium tuberculosis K infection
Jaehun Park, Hongmin Kim, Kee Woong Kwon, Hong-Hee Choi, Soon Myung Kang, Jung Joo Hong & Sung Jae Shin
Pages: 430-445
Published online: 13 May 2020
AbstractforToll-like receptor 4 signaling-mediated responses are critically engaged in optimal host protection against highly virulent Mycobacterium tuberculosis K infection | Full Text | References | PDF (5.7 MB) | EPUB
  • 1774 Views
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Research paper

Article
Identification of conditionally essential genes for Streptococcus suis infection in pigs
Jesús Arenas, Aldert Zomer, Jose Harders-Westerveen, Hester J. Bootsma, Marien I. De Jonge, Norbert Stockhofe-Zurwieden, Hilde E. Smith & Astrid De Greeff
Pages: 446-464
Published online: 18 May 2020
AbstractforIdentification of conditionally essential genes for Streptococcus suis infection in pigs | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 4248 Views
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Article
Relevance of inducible nitric oxide synthase for immune control of Mycobacterium avium subspecies paratuberculosis infection in mice
Ketema Abdissa, Nanthapon Ruangkiattikul, Wiebke Ahrend, Andreas Nerlich, Andreas Beineke, Kristin Laarmann, Nina Janze, Ulrike Lobermeyer, Abdulhadi Suwandi, Christine Falk, Ulrike Schleicher, Christian Bogdan, Siegfried Weiss & Ralph Goethe
Pages: 465-481
Published online: 14 May 2020
AbstractforRelevance of inducible nitric oxide synthase for immune control of Mycobacterium avium subspecies paratuberculosis infection in mice | Full Text | References | PDF (6.2 MB) | EPUB | Supplemental
  • 1813 Views
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Research Article

Article
A case series describing the epidemiology and clinical characteristics of COVID-19 infection in Jilin Province
Na Du, Haiying Chen, Qing Zhang, Lihe Che, Lixin Lou, Xiaohua Li, Kaiyu Zhang & Wanguo Bao
Pages: 482-485
Published online: 22 May 2020
AbstractforA case series describing the epidemiology and clinical characteristics of COVID-19 infection in Jilin Province | Full Text | References | PDF (1 MB) | EPUB
  • 4301 Views
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Editorial

Editorial
Mice with humanized-lungs and immune system - an idealized model for COVID-19 and other respiratory illness
Sujit Pujhari & Jason L Rasgon
Pages: 486-488
Published online: 20 May 2020
AbstractforMice with humanized-lungs and immune system - an idealized model for COVID-19 and other respiratory illness | Full Text | References | PDF (802.1 KB) | EPUB
  • 5194 Views
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Research Article

Article
Rab18 binds to classical swine fever virus NS5A and mediates viral replication and assembly in swine umbilical vein endothelial cells
Liang Zhang, Di Zhao, Mingxing Jin, Mengzhao Song, Shanchuan Liu, Kangkang Guo & Yanming Zhang
Pages: 489-501
Published online: 18 May 2020
AbstractforRab18 binds to classical swine fever virus NS5A and mediates viral replication and assembly in swine umbilical vein endothelial cells | Full Text | References | PDF (4.5 MB) | EPUB
  • 1573 Views
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Article
UvrY is required for the full virulence of Aeromonas dhakensis
Yi-Wei Chen, Wen-Hsuan Yeh, Hung-Jen Tang, Jenn-Wei Chen, Hung-Yu Shu, Yu-Chen Su, Sin-Tian Wang, Cheng-Ju Kuo, Yin-Ching Chuang, Chi-Chung Chen, Wen-Chien Ko, Chang-Shi Chen & Po-Lin Chen
Pages: 502-520
Published online: 20 May 2020
AbstractforUvrY is required for the full virulence of Aeromonas dhakensis | Full Text | References | PDF (5.9 MB) | EPUB | Supplemental
  • 2150 Views
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Research Paper

Article
PepO is a target of the two-component systems VicRK and CovR required for systemic virulence of Streptococcus mutans
Lívia A. Alves, Tridib Ganguly, Érika N. Harth-Chú, Jessica Kajfasz, José A. Lemos, Jacqueline Abranches & Renata O. Mattos-Graner
Pages: 521-536
Published online: 19 May 2020
AbstractforPepO is a target of the two-component systems VicRK and CovR required for systemic virulence of Streptococcus mutans | Full Text | References | PDF (3.9 MB) | EPUB
  • 1756 Views
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Research Article

Article
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation
Lei You, Junbo Chen, Weiyong Liu, Qi Xiang, Zhen Luo, Wenbiao Wang, Wei Xu, Kailang Wu, Qi Zhang, Yingle Liu & Jianguo Wu
Pages: 537-553
Published online: 20 May 2020
AbstractforEnterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation | Full Text | References | PDF (7 MB) | EPUB | Supplemental
  • 4161 Views
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Research Paper

Article
Putative determinants of virulence in Melissococcus plutonius, the bacterial agent causing European foulbrood in honey bees
Daniela Grossar, Verena Kilchenmann, Eva Forsgren, Jean-Daniel Charrière, Laurent Gauthier, Michel Chapuisat & Vincent Dietemann
Pages: 554-567
Published online: 26 May 2020
AbstractforPutative determinants of virulence in Melissococcus plutonius, the bacterial agent causing European foulbrood in honey bees | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 3517 Views
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Article
The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis
Catherine S. Nation, Akram A. Da’Dara & Patrick J. Skelly
Pages: 568-579
Published online: 22 May 2020
AbstractforThe essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis | Full Text | References | PDF (3.5 MB) | EPUB
  • 1238 Views
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Article
Contribution of NKT cells to the immune response and pathogenesis triggered by respiratory viruses
Emma Rey-Jurado, Karen Bohmwald, Nicolás M.S. Gálvez, Daniela Becerra, Steven A. Porcelli, Leandro J. Carreño & Alexis M. Kalergis
Pages: 580-593
Published online: 28 May 2020
AbstractforContribution of NKT cells to the immune response and pathogenesis triggered by respiratory viruses | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 2086 Views
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Article
B cell intrinsic expression of IFNλ receptor suppresses the acute humoral immune response to experimental blood-stage malaria
William O. Hahn, Marion Pepper & W. Conrad Liles
Pages: 594-606
Published online: 07 Jun 2020
AbstractforB cell intrinsic expression of IFNλ receptor suppresses the acute humoral immune response to experimental blood-stage malaria | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 1734 Views
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Article
TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein
Zhiqiang Duan, Chao Yuan, Yifan Han, Lei Zhou, Jiafu Zhao, Yong Ruan, Jiaqi Chen, Mengmeng Ni & Xinqin Ji
Pages: 607-635
Published online: 27 Jun 2020
AbstractforTMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein | Full Text | References | PDF (5.6 MB) | EPUB | Supplemental
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Research paper

Article
Insights into idarubicin antimicrobial activity against methicillin-resistant Staphylococcus aureus
Pengfei She, Shijia Li, Linying Zhou, Zhen Luo, Jinfeng Liao, Lanlan Xu, Xianghai Zeng, Ti Chen, Yaqian Liu & Yong Wu
Pages: 636-651
Published online: 29 May 2020
AbstractforInsights into idarubicin antimicrobial activity against methicillin-resistant Staphylococcus aureus | Full Text | References | PDF (6.4 MB) | EPUB | Supplemental
  • 1995 Views
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Research Paper

Article
Identification of FDA-approved antivirulence drugs targeting the Pseudomonas aeruginosa quorum sensing effector protein PqsE
Valerio Baldelli, Francesca D’Angelo, Viola Pavoncello, Ersilia Vita Fiscarelli, Paolo Visca, Giordano Rampioni & Livia Leoni
Pages: 652-668
Published online: 28 May 2020
AbstractforIdentification of FDA-approved antivirulence drugs targeting the Pseudomonas aeruginosa quorum sensing effector protein PqsE | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
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Article
Establishment of stable Vero cell lines expressing TMPRSS2 and MSPL: A useful tool for propagating porcine epidemic diarrhea virus in the absence of exogenous trypsin
Xiaona Wang, Xinyuan Qiao, Ling Sui, Haiyuan Zhao, Fengsai Li, Yan-Dong Tang, Wen Shi, Yuyao Guo, Yanping Jiang, Li Wang, Han Zhou, Lijie Tang, Yigang Xu & Yijing Li
Pages: 669-685
Published online: 29 May 2020
AbstractforEstablishment of stable Vero cell lines expressing TMPRSS2 and MSPL: A useful tool for propagating porcine epidemic diarrhea virus in the absence of exogenous trypsin | Full Text | References | PDF (5.8 MB) | EPUB | Supplemental
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Research paper

Article
Measles in Romania – clinical and epidemiological characteristics of hospitalized measles cases during the first three years of the 2016-ongoing epidemic
Daniela Pițigoi, Oana Săndulescu, Maria Dorina Crăciun, Anca Drăgănescu, Gheorghiță Jugulete, Anca Streinu-Cercel, Angelica Vișan, Claudia Rîciu, Alexandru Rafila, Victoria Aramă, Monica Luminos & Adrian Streinu-Cercel
Pages: 686-694
Published online: 07 Jun 2020
AbstractforMeasles in Romania – clinical and epidemiological characteristics of hospitalized measles cases during the first three years of the 2016-ongoing epidemic | Full Text | References | PDF (863.5 KB) | EPUB
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Article
Bacterial adhesion inhibitor prevents infection in a rodent surgical incision model
R. M. Huebinger, D. H. Do, D. L. Carlson, X. Yao, D. H. Stones, M. De Souza Santos, D. P. Vaz, E. Keen, S. E. Wolf, JP Minei, K. P. Francis, K. Orth & A. M. Krachler
Pages: 695-706
Published online: 03 Jun 2020
AbstractforBacterial adhesion inhibitor prevents infection in a rodent surgical incision model | Full Text | References | PDF (5.7 MB) | EPUB
  • 1372 Views
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Article
Development of a TaqMan-probe-based multiplex real-time PCR for the simultaneous detection of emerging and reemerging swine coronaviruses
Zhongzhou Pan, Jiaxuan Lu, Ningning Wang, Wan-Ting He, Letian Zhang, Wen Zhao & Shuo Su
Pages: 707-718
Published online: 03 Jun 2020
AbstractforDevelopment of a TaqMan-probe-based multiplex real-time PCR for the simultaneous detection of emerging and reemerging swine coronaviruses | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
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Article
Titan cell formation is unique to Cryptococcus species complex
Mariusz Dyląg, Rodney J. Colon-Reyes & Lukasz Kozubowski
Pages: 719-729
Published online: 04 Jun 2020
AbstractforTitan cell formation is unique to Cryptococcus species complex | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Article
Clinical and epidemiological characterization of severe Plasmodium vivax malaria in Gujarat, India
Anupkumar R. Anvikar, Anna Maria van Eijk, Asha Shah, Kamlesh J. Upadhyay, Steven A. Sullivan, Ankita J. Patel, Jaykumar M. Joshi, Suchi Tyagi, Ranvir Singh, Jane M. Carlton, Himanshu Gupta & Samuel C. Wassmer
Pages: 730-738
Published online: 03 Jun 2020
AbstractforClinical and epidemiological characterization of severe Plasmodium vivax malaria in Gujarat, India | Full Text | References | PDF (457.9 KB) | EPUB | Supplemental
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Article
Arachidonic acid metabolism is elevated in Mycoplasma gallisepticum and Escherichia coli co-infection and induces LTC4 in serum as the biomarker for detecting poultry respiratory disease
Zhiyong Wu, Chunli Chen, Qiaomei Zhang, Jiaxin Bao, Qianqian Fan, Rui Li, Muhammad Ishfaq & Jichang Li
Pages: 730-738
Published online: 03 Jun 2020
AbstractforArachidonic acid metabolism is elevated in Mycoplasma gallisepticum and Escherichia coli co-infection and induces LTC4 in serum as the biomarker for detecting poultry respiratory disease | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
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Research Paper

Article
New insights into the evolution of host specificity of three Penicillium species and the pathogenicity of P. Italicum involving the infection of Valencia orange (Citrus sinensis)
Liang Gong, Yongfeng Liu, Yehui Xiong, Taotao Li, Chunxiao Yin, Juanni Zhao, Jialin Yu, Qi Yin, Vijai Kumar Gupta, Yueming Jiang & Xuewu Duan
Pages: 748-768
Published online: 11 Jun 2020
AbstractforNew insights into the evolution of host specificity of three Penicillium species and the pathogenicity of P. Italicum involving the infection of Valencia orange (Citrus sinensis) | Full Text | References | PDF (7.1 MB) | EPUB | Supplemental
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Research paper

Article
The interaction between flagellin and the glycosphingolipid Gb3 on host cells contributes to Bacillus cereus acute infection
Song Gao, Chengpei Ni, Wenhua Huang, Huaijie Hao, Hua Jiang, Qingyu Lv, Yuling Zheng, Peng Liu, Decong Kong & Yongqiang Jiang
Pages: 769-780
Published online: 07 Jun 2020
AbstractforThe interaction between flagellin and the glycosphingolipid Gb3 on host cells contributes to Bacillus cereus acute infection | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Research Paper

Article
Transcriptional host–pathogen responses of Pseudogymnoascus destructans and three species of bats with white-nose syndrome
Christina M. Davy, Michael E. Donaldson, Hana Bandouchova, Ana M. Breit, Nicole A.S. Dorville, Yvonne A. Dzal, Veronika Kovacova, Emma L. Kunkel, Natália Martínková, Kaleigh J.O. Norquay, James E. Paterson, Jan Zukal, Jiri Pikula, Craig K.R. Willis & Christopher J. Kyle
Pages: 781-794
Published online: 17 Jun 2020
AbstractforTranscriptional host–pathogen responses of Pseudogymnoascus destructans and three species of bats with white-nose syndrome | Full Text | References | PDF (4.1 MB) | EPUB | Supplemental
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Brief Report

Brief Report
Attenuation of Pseudomonas aeruginosa infection by INP0341, a salicylidene acylhydrazide, in a murine model of keratitis
Prerana Sharma, Mikael Elofsson & Sanhita Roy
Pages: 795-804
Published online: 07 Jun 2020
AbstractforAttenuation of Pseudomonas aeruginosa infection by INP0341, a salicylidene acylhydrazide, in a murine model of keratitis | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Editorial

Editorial
Autophagy and SARS-CoV-2 infection: A possible smart targeting of the autophagy pathway
Shahla Shojaei, Madhumita Suresh, Daniel J. Klionsky, Hagar Ibrahim Labouta & Saeid Ghavami
Pages: 805-810
Published online: 22 Jun 2020
AbstractforAutophagy and SARS-CoV-2 infection: A possible smart targeting of the autophagy pathway | Full Text | References | PDF (1,015.4 KB) | EPUB
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Research paper

Article
A novel biosafety level 2 compliant tuberculosis infection model using a ΔleuDΔpanCD double auxotroph of Mycobacterium tuberculosis H37Rv and Galleria mellonella
Masanori Asai, Yanwen Li, John Spiropoulos, William Cooley, David Everest, Brian D. Robertson, Paul R. Langford & Sandra M. Newton
Pages: 811-824
Published online: 24 Jun 2020
AbstractforA novel biosafety level 2 compliant tuberculosis infection model using a ΔleuDΔpanCD double auxotroph of Mycobacterium tuberculosis H37Rv and Galleria mellonella | Full Text | References | PDF (7.3 MB) | EPUB | Supplemental
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Article
Screening for phagocytosis resistance-related genes via a transposon mutant library of Streptococcus suis serotype 2
Xiaomeng Pei, Mingxing Liu, Hong Zhou & Hongjie Fan
Pages: 825-838
Published online: 02 Jul 2020
AbstractforScreening for phagocytosis resistance-related genes via a transposon mutant library of Streptococcus suis serotype 2 | Full Text | References | PDF (3.2 MB) | EPUB
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Article
Chemotactic invasion in deep soft tissue by Vibrio vulnificus is essential for the progression of necrotic lesions
Kohei Yamazaki, Takashige Kashimoto, Takehiro Kado, Yukihiro Akeda, Kazuki Yoshioka, Toshio Kodama, Mai Yamamoto, Masashi Okamura, Tsutomu Kakuda & Shunji Ueno
Pages: 839-847
Published online: 27 Jun 2020
AbstractforChemotactic invasion in deep soft tissue by Vibrio vulnificus is essential for the progression of necrotic lesions | Full Text | References | PDF (3 MB) | EPUB | Supplemental
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Research Paper

Article
miR-9875 functions in antiviral immunity by targeting PDCD6 in mud crab (Scylla paramamosain)
Yi Gong, Tongtong Kong, Xin Ren, Shanmeng Lin & Shengkang Li
Pages: 848-861
Published online: 28 Jun 2020
AbstractformiR-9875 functions in antiviral immunity by targeting PDCD6 in mud crab (Scylla paramamosain) | Full Text | References | PDF (9.9 MB) | EPUB
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Research paper

Article
Differential adaptability between reference strains and clinical isolates of Pseudomonas aeruginosa into the lung epithelium intracellular lifestyle
Maria Del Mar Cendra & Eduard Torrents
Pages: 862-876
Published online: 22 Jul 2020
AbstractforDifferential adaptability between reference strains and clinical isolates of Pseudomonas aeruginosa into the lung epithelium intracellular lifestyle | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
  • 1899 Views
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Research Paper

Article
Maltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature
Ming Jiang, Li-Fen Yang, Jun Zheng, Zhuang-Gui Chen & Bo Peng
Pages: 877-888
Published online: 22 Jul 2020
AbstractforMaltose promotes crucian carp survival against Aeromonas sobrial infection at high temperature | Full Text | References | PDF (9.5 MB) | EPUB | Supplemental
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Review article

Review Article
Elite controllers: A heterogeneous group of HIV-infected patients
María A. Navarrete-Muñoz, Clara Restrepo, José M. Benito & Norma Rallón
Pages: 889-897
Published online: 22 Jul 2020
AbstractforElite controllers: A heterogeneous group of HIV-infected patients | Full Text | References | PDF (1.5 MB) | EPUB
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Review Article
PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interaction
Flavio De Maio, Rita Berisio, Riccardo Manganelli & Giovanni Delogu
Pages: 898-915
Published online: 25 Jul 2020
AbstractforPE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interaction | Full Text | References | PDF (7.8 MB) | EPUB | Supplemental
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Research paper

Article
Phylogenetic and codon usage analysis of atypical porcine pestivirus (APPV)
Shuonan Pan, Chunxiao Mou, Huiguang Wu & Zhenhai Chen
Pages: 916-926
Published online: 29 Jul 2020
AbstractforPhylogenetic and codon usage analysis of atypical porcine pestivirus (APPV) | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
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Article
Inactivation of the htpsA gene affects capsule development and pathogenicity of Streptococcus suis
Hua Ni, Min Li, Qiaoqiao Wang, Jing Wang, Xumiao Liu, Feng Zheng, Dan Hu, Xu Yu, Yifang Han, Qi Zhang, Tingting Zhou, Yiwen Wang, Chunhui Wang, Jimin Gao, Zhu-Qing Shao & Xiuzhen Pan
Pages: 927-940
Published online: 20 Aug 2020
AbstractforInactivation of the htpsA gene affects capsule development and pathogenicity of Streptococcus suis | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
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Editorial

Editorial
Enteric involvement of SARS-CoV-2: Implications for the COVID-19 management, transmission, and infection control
Jiandong Shi, Jing Sun & Yunzhang Hu
Pages: 941-944
Published online: 27 Jul 2020
First Page PreviewforEnteric involvement of SARS-CoV-2: Implications for the COVID-19 management, transmission, and infection control | Full Text | References | PDF (221 KB) | EPUB
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Editorial
Mammalian malaria: Remembering the Alamo
Colin J. Sutherland
Pages: 945-946
Published online: 27 Jul 2020
CitationforMammalian malaria: Remembering the Alamo | Full Text | References | PDF (213.9 KB) | EPUB
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Research paper

Article
Exoproteomic profiling uncovers critical determinants for virulence of livestock-associated and human-originated Staphylococcus aureus ST398 strains
Xin Zhao, Monika A. Chlebowicz-Flissikowska, Min Wang, Elias Vera Murguia, Anne de Jong, Dörte Becher, Sandra Maaß, Girbe Buist & Jan Maarten van Dijl
Pages: 947-963
Published online: 29 Jul 2020
AbstractforExoproteomic profiling uncovers critical determinants for virulence of livestock-associated and human-originated Staphylococcus aureus ST398 strains | Full Text | References | PDF (6.1 MB) | EPUB | Supplemental
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Article
Development of a fully automated high throughput PCR for the detection of SARS-CoV-2: The need for speed
Florian J. Mayer, Franz Ratzinger, Ralf L.J. Schmidt, Georg Greiner, Olfert Landt, Alexander Am Ende, Victor M. Corman, Nicole Perkmann-Nagele, Thomas Watkins-Riedel, Dagmar Petermann, Karoline Abadir, Josef Zweimüller-Mayer & Robert Strassl
Pages: 964-967
Published online: 29 Jul 2020
AbstractforDevelopment of a fully automated high throughput PCR for the detection of SARS-CoV-2: The need for speed | Full Text | References | PDF (284 KB) | EPUB | Supplemental
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Article
Transcriptional remodeling during metacyclogenesis in Trypanosoma cruzi I
Lissa Cruz-Saavedra, Gustavo A. Vallejo, Felipe Guhl, Louisa A. Messenger & Juan David Ramírez
Pages: 968-979
Published online: 27 Jul 2020
AbstractforTranscriptional remodeling during metacyclogenesis in Trypanosoma cruzi I | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
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Article
Bacteria elevate extracellular adenosine to exploit host signaling for blood-brain barrier disruption
Zunquan Zhao, Xueyi Shang, Ying Chen, Yuling Zheng, Wenhua Huang, Hua Jiang, Qingyu Lv, Decong Kong, Yongqiang Jiang & Peng Liu
Pages: 980-994
Published online: 10 Aug 2020
AbstractforBacteria elevate extracellular adenosine to exploit host signaling for blood-brain barrier disruption | Full Text | References | PDF (12.8 MB) | EPUB | Supplemental
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Article
Outer membrane vesicles produced by Burkholderia cepacia cultured with subinhibitory concentrations of ceftazidime enhance pro-inflammatory responses
Se Yeon Kim, Mi Hyun Kim, Joo Hee Son, Seung Il Kim, Sung Ho Yun, Kyeongmin Kim, Shukho Kim, Minsang Shin & Je Chul Lee
Pages: 995-1005
Published online: 15 Aug 2020
AbstractforOuter membrane vesicles produced by Burkholderia cepacia cultured with subinhibitory concentrations of ceftazidime enhance pro-inflammatory responses | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
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Article
Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study
Chao Yu, Miao Zhou, Yang Liu, Tinglin Guo, Chongyang Ou, Liye Yang, Yan Li, Dongliang Li, Xinyu Hu, Li Shuai, Bin Wang & Zui Zou
Pages: 1006-1014
Published online: 12 Aug 2020
AbstractforCharacteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Article
Epidemiological and clinical differences of coronavirus disease 2019 patients with distinct viral exposure history
Yinjie Gao, Xuemei Ma, Jingfeng Bi, Jindong Chu, Bo Liu, Chunsheng Chi, Jianguo Yan, Xiaoli Yu, Fangming Liu, Xiaohong Deng, Hongbing Zhang & Bo Jin
Pages: 1015-1023
Published online: 12 Aug 2020
AbstractforEpidemiological and clinical differences of coronavirus disease 2019 patients with distinct viral exposure history | Full Text | References | PDF (944.6 KB) | EPUB
  • 2655 Views
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Article
The Peptidoglycan-associated lipoprotein Pal contributes to the virulence of Burkholderia mallei and provides protection against lethal aerosol challenge
Jeremy S. Dyke, Maria Cristina Huertas-Diaz, Frank Michel, Nathan E. Holladay, Robert J. Hogan, Biao He & Eric R. Lafontaine
Pages: 1024-1040
Published online: 15 Aug 2020
AbstractforThe Peptidoglycan-associated lipoprotein Pal contributes to the virulence of Burkholderia mallei and provides protection against lethal aerosol challenge | Full Text | References | PDF (3.6 MB) | EPUB
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Article
A DUF4148 family protein produced inside RAW264.7 cells is a critical Burkholderia pseudomallei virulence factor
Susan Welkos, Irma Blanco, Udoka Okaro, Jennifer Chua & David DeShazer
Pages: 1041-1058
Published online: 23 Aug 2020
AbstractforA DUF4148 family protein produced inside RAW264.7 cells is a critical Burkholderia pseudomallei virulence factor | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
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Article
Mycoplasma hyopneumoniae evades complement activation by binding to factor H via elongation factor thermo unstable (EF-Tu)
Yanfei Yu, Jia Wang, Rui Han, Li Wang, Lei Zhang, Amy Yimin Zhang, Jiuqing Xin, Shaoli Li, Yanhua Zeng, Guoqing Shao, Zhixin Feng & Qiyan Xiong
Pages: 1059-1074
Published online: 20 Aug 2020
AbstractforMycoplasma hyopneumoniae evades complement activation by binding to factor H via elongation factor thermo unstable (EF-Tu) | Full Text | References | PDF (9.8 MB) | EPUB | Supplemental
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Article
Tobacco Hornworm (Manduca sexta) caterpillars as a novel host model for the study of fungal virulence and drug efficacy
Naomi Lyons, Isabel Softley, Andrew Balfour, Carolyn Williamson, Heath E. O’Brien, Amol C. Shetty, Vincent M. Bruno & Stephanie Diezmann
Pages: 1075-1089
Published online: 25 Aug 2020
AbstractforTobacco Hornworm (Manduca sexta) caterpillars as a novel host model for the study of fungal virulence and drug efficacy | Full Text | References | PDF (6 MB) | EPUB | Supplemental
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Article
Surfactant phospholipids act as molecular switches for premature induction of quorum sensing-dependent virulence in Pseudomonas aeruginosa
Zhizhou Kuang, Richard C. Bennett, Jingjun Lin, Yonghua Hao, Luchang Zhu, Henry T. Akinbi & Gee W. Lau
Pages: 1090-1107
Published online: 25 Aug 2020
AbstractforSurfactant phospholipids act as molecular switches for premature induction of quorum sensing-dependent virulence in Pseudomonas aeruginosa | Full Text | References | PDF (2.8 MB) | EPUB
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Article
Cu transporter protein CrpF protects against Cu-induced toxicity in Fusarium oxysporum
Damaris Lorenzo-Gutiérrez, Lucía Gómez-Gil, Josep Guarro, M. Isabel G. Roncero, Javier Capilla & Loida López-Fernández
Pages: 1108-1121
Published online: 30 Aug 2020
AbstractforCu transporter protein CrpF protects against Cu-induced toxicity in Fusarium oxysporum | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
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Article
Neutrophil extracellular traps (NETs)-mediated killing of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) are impaired in patients with diabetes mellitus
Longyang Jin, Yudong Liu, Chendi Jing, Ruobing Wang, Qi Wang & Hui Wang
Pages: 1122-1130
Published online: 29 Aug 2020
AbstractforNeutrophil extracellular traps (NETs)-mediated killing of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) are impaired in patients with diabetes mellitus | Full Text | References | PDF (5.6 MB) | EPUB | Supplemental
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Article
Virulent infection of outbred Hartley guinea pigs with recombinant Pichinde virus as a surrogate small animal model for human Lassa fever
Shuiyun Lan, Wun-Ju Shieh, Qinfeng Huang, Sherif R. Zaki, Yuying Liang & Hinh Ly
Pages: 1131-1141
Published online: 30 Aug 2020
AbstractforVirulent infection of outbred Hartley guinea pigs with recombinant Pichinde virus as a surrogate small animal model for human Lassa fever | Full Text | References | PDF (4.7 MB) | EPUB
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Article
Pathogenesis of Staphylococcus haemolyticus on primary human skin fibroblast cells
Hala O. Eltwisy, Medhat Abdel-Fattah, Amani M. Elsisi, Mahmoud M. Omar, Ahmed Aly Abdelmoteleb & Mohamed A. El-Mokhtar
Pages: 1142-1157
Published online: 30 Aug 2020
AbstractforPathogenesis of Staphylococcus haemolyticus on primary human skin fibroblast cells | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
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Article
Screening of immune biomarkers in different breeds of chickens infected with J subgroup of avian leukemia virus by proteomic
Fei Ye, Yan Wang, Qijian He, Zhaoshuo Wang, Enyue Ma, Shiliang Zhu, Heling Yu, Huadong Yin, Xiaoling Zhao, Diyan Li, Hengyong Xu, Hua Li & Qing Zhu
Pages: 1158-1176
Published online: 30 Aug 2020
AbstractforScreening of immune biomarkers in different breeds of chickens infected with J subgroup of avian leukemia virus by proteomic | Full Text | References | PDF (10.9 MB) | EPUB
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Review article

Review Article
The spreading of parasites by human migratory activities
Dietmar Steverding
Pages: 1177-1191
Published online: 30 Aug 2020
AbstractforThe spreading of parasites by human migratory activities | Full Text | References | PDF (1.1 MB) | EPUB
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Review Article
Trehalose and bacterial virulence
Muthita Vanaporn & Richard W Titball
Pages: 1192-1202
Published online: 30 Aug 2020
AbstractforTrehalose and bacterial virulence | Full Text | References | PDF (554.2 KB) | EPUB
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Article
Canine parvovirus induces G1/S cell cycle arrest that involves EGFR Tyr1086 phosphorylation
Xiaofeng Dai, Xuanhao Zhang, Yujie Miao, Peiyu Han & Jianying Zhang
Pages: 1203-1214
Published online: 02 Sep 2020
AbstractforCanine parvovirus induces G1/S cell cycle arrest that involves EGFR Tyr1086 phosphorylation | Full Text | References | PDF (4.8 MB) | EPUB | Supplemental
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Article
Hypervirulent Klebsiella pneumoniae is emerging as an increasingly prevalent K. pneumoniae pathotype responsible for nosocomial and healthcare-associated infections in Beijing, China
Chao Liu, Pengcheng Du, Nan Xiao, Fansen Ji, Thomas A. Russo, Jun Guo & the China Surveillance of Hypervirulent Klebsiella pneumoniae(CS-HVKP) Research Group.
Pages: 1215-1224
Published online: 12 Sep 2020
AbstractforHypervirulent Klebsiella pneumoniae is emerging as an increasingly prevalent K. pneumoniae pathotype responsible for nosocomial and healthcare-associated infections in Beijing, China | Full Text | References | PDF (511.7 KB) | EPUB | Supplemental
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Article
Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis
Young Jae Kim, Sang-Hee Lee, Sang Min Jeon, Prashanta Silwal, Ju-Young Seo, Bui Thi Bich Hanh, June-Woo Park, Jake Whang, Min Joung Lee, Jun Young Heo, Soon Ha Kim, Jin-Man Kim, Gyu Yong Song, Jichan Jang & Eun-Kyeong Jo
Pages: 1225-1239
Published online: 09 Sep 2020
AbstractforSirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis | Full Text | References | PDF (7.1 MB) | EPUB | Supplemental
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Review Article

Review Article
Clinical characteristics of family-clustered onset of coronavirus disease 2019 in Jilin Province, China
Na Du, Yanfang Jiang, Qing Zhang, Lihe Che, Xiaohua Li, Lixin Lou, Wanguo Bao & Shucheng Hua
Pages: 1240-1249
Published online: 15 Sep 2020
AbstractforClinical characteristics of family-clustered onset of coronavirus disease 2019 in Jilin Province, China | Full Text | References | PDF (11.9 MB) | EPUB
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Research Article

Article
Exploration of turn-positive RT-PCR results and factors related to treatment outcome in COVID-19: A retrospective cohort study
Yong Xiao, Xiao Shi, Qian She, Qi Chen, Hong Pan, Jin Zhang, Xiaojiao Liu, Haiyan Wu, Wenfei Jin, Ge Ke, Shuzhong Liu, Jiao Li, Jing Zhou, Dongwen Wu, Fen Wang, Honggang Yu & Mingkai Chen
Pages: 1250-1256
Published online: 13 Sep 2020
AbstractforExploration of turn-positive RT-PCR results and factors related to treatment outcome in COVID-19: A retrospective cohort study | Full Text | References | PDF (306.8 KB) | EPUB | Supplemental
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Article
CRISPR-cas system in the acquisition of virulence genes in dental-root canal and hospital-acquired isolates of Enterococcus faecalis
Pourya Gholizadeh, Mohammad Aghazadeh, Reza Ghotaslou, Mohammad Ahangarzadeh Rezaee, Tahereh Pirzadeh, Şükran Köse, Khudaverdi Ganbarov, Mehdi Yousefi & Hossein Samadi Kafil
Pages: 1257-1267
Published online: 15 Sep 2020
AbstractforCRISPR-cas system in the acquisition of virulence genes in dental-root canal and hospital-acquired isolates of Enterococcus faecalis | Full Text | References | PDF (958.9 KB) | EPUB
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Article
Coxiella burnetii replicates in Galleria mellonella hemocytes and transcriptome mapping reveals in vivo regulated genes
Andrea Kovacs-Simon, Georgie Metters, Isobel Norville, Claudia Hemsley & Richard W. Titball
Pages: 1268-1278
Published online: 24 Sep 2020
AbstractforCoxiella burnetii replicates in Galleria mellonella hemocytes and transcriptome mapping reveals in vivo regulated genes | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Article
The Tat system and its dependent cell division proteins are critical for virulence of extra-intestinal pathogenic Escherichia coli
Jinjin Liu, Fan Yin, Te Liu, Shaowen Li, Chen Tan, Lu Li, Rui Zhou & Qi Huang
Pages: 1279-1292
Published online: 22 Sep 2020
AbstractforThe Tat system and its dependent cell division proteins are critical for virulence of extra-intestinal pathogenic Escherichia coli | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
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Article
Identification and validation of a novel anti-virulent that binds to pyoverdine and inhibits its function
Xu Wang, Quinn Kleerekoper, Alexey V. Revtovich, Donghoon Kang & Natalia V. Kirienko
Pages: 1293-1309
Published online: 22 Sep 2020
AbstractforIdentification and validation of a novel anti-virulent that binds to pyoverdine and inhibits its function | Full Text | References | PDF (8.1 MB) | EPUB | Supplemental
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Article
Exploring metal availability in the natural niche of Streptococcus pneumoniae to discover potential vaccine antigens
Lucille F. van Beek, Kristin Surmann, H. Bart van den Berg van Saparoea, Diane Houben, Wouter S. P. Jong, Christian Hentschker, Thomas H. A. Ederveen, Elena Mitsi, Daniela M. Ferreira, Fred van Opzeeland, Christa E. van der Gaast – de Jongh, Irma Joosten, Uwe Völker, Frank Schmidt, Joen Luirink, Dimitri A. Diavatopoulos & Marien I. de Jonge
Pages: 1310-1328
Published online: 05 Oct 2020
AbstractforExploring metal availability in the natural niche of Streptococcus pneumoniae to discover potential vaccine antigens | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Article
Live imaging and quantitative analysis of Aspergillus fumigatus growth and morphology during inter-microbial interaction with Pseudomonas aeruginosa
Sebastian Wurster, Gabriele Sass, Nathaniel D. Albert, Hasan Nazik, Eric Déziel, David A. Stevens & Dimitrios P. Kontoyiannis
Pages: 1329-1336
Published online: 05 Oct 2020
AbstractforLive imaging and quantitative analysis of Aspergillus fumigatus growth and morphology during inter-microbial interaction with Pseudomonas aeruginosa | Full Text | References | PDF (5.2 MB) | EPUB | Supplemental
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Article
Proteome analysis of bronchoalveolar lavage fluids reveals host and fungal proteins highly expressed during invasive pulmonary aspergillosis in mice and humans
Silke Machata, Mario M. Müller, Roland Lehmann, Patricia Sieber, Gianni Panagiotou, Agostinho Carvalho, Cristina Cunha, Katrien Lagrou, Johan Maertens, Hortense Slevogt & Ilse D. Jacobsen
Pages: 1337-1351
Published online: 12 Oct 2020
AbstractforProteome analysis of bronchoalveolar lavage fluids reveals host and fungal proteins highly expressed during invasive pulmonary aspergillosis in mice and humans | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
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Article
Transcriptomic analyses reveal comprehensive responses of insect hemocytes to mycopathogen Beauveria bassiana, and fungal virulence-related cell wall protein assists pathogen to evade host cellular defense
Jin-Li Ding, Jia Hou, Ming-Guang Feng & Sheng-Hua Ying
Pages: 1352-1365
Published online: 05 Oct 2020
AbstractforTranscriptomic analyses reveal comprehensive responses of insect hemocytes to mycopathogen Beauveria bassiana, and fungal virulence-related cell wall protein assists pathogen to evade host cellular defense | Full Text | References | PDF (10.1 MB) | EPUB | Supplemental
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Article
A mutation in C. neoformans mitochondrial NADH dehydrogenase results in increased virulence in mice
Mitch Merryman, Jacob Crigler, Rebecca Seipelt-Thiemann & Erin McClelland
Pages: 1366-1378
Published online: 24 Oct 2020
AbstractforA mutation in C. neoformans mitochondrial NADH dehydrogenase results in increased virulence in mice | Full Text | References | PDF (768.7 KB) | EPUB
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Article
Nucleolar protein NPM1 is essential for circovirus replication by binding to viral capsid
Jianwei Zhou, Yadong Dai, Cui Lin, Ying Zhang, Zixuan Feng, Weiren Dong, Yulan Jin, Yan Yan, Jiyong Zhou & Jinyan Gu
Pages: 1379-1393
Published online: 19 Oct 2020
AbstractforNucleolar protein NPM1 is essential for circovirus replication by binding to viral capsid | Full Text | References | PDF (7.4 MB) | EPUB
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Article
Reliability of induced sputum test is greater than that of throat swab test for detecting SARS-CoV-2 in patients with COVID-19: A multi-center cross-sectional study
Tianwen Lai, Fangfei Xiang, Jianfeng Zeng, Yingzi Huang, Liping Jia, Hui Chen, Jiayuan Wu, Jianfeng Xie, Shuna Liu, Wei Deng, Weiqiang Zheng, Yang Huang, Qinfu Zhang, Qingfeng Luo, Fan Mo, Lieming Long, Wuying Zhang, Wenna Chen & Huanqin Han
Pages: 1394-1401
Published online: 19 Oct 2020
AbstractforReliability of induced sputum test is greater than that of throat swab test for detecting SARS-CoV-2 in patients with COVID-19: A multi-center cross-sectional study | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Respiratory ß-2-Microglobulin exerts pH dependent antimicrobial activity
Armin Holch, Richard Bauer, Lia-Raluca Olari, Armando A. Rodriguez, Ludger Ständker, Nico Preising, Merve Karacan, Sebastian Wiese, Paul Walther, Yasser B. Ruiz-Blanco, Elsa Sanchez-Garcia, Christian Schumann, Jan Münch & Barbara Spellerberg
Pages: 1402-1414
Published online: 22 Oct 2020
AbstractforRespiratory ß-2-Microglobulin exerts pH dependent antimicrobial activity | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
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Article
P-type Na+/K+ ATPases essential and nonessential for cellular homeostasis and insect pathogenicity of Beauveria bassiana
Ya-Ni Mou, Ben-Jie Gao, Kang Ren, Sen-Miao Tong, Sheng-Hua Ying & Ming-Guang Feng
Pages: 1415-1431
Published online: 24 Oct 2020
AbstractforP-type Na+/K+ ATPases essential and nonessential for cellular homeostasis and insect pathogenicity of Beauveria bassiana | Full Text | References | PDF (7.7 MB) | EPUB | Supplemental
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Article
Aminoglycoside riboswitch control of the expression of integron associated aminoglycoside resistance adenyltransferases
Jun Zhang, Getong Liu, Xuhui Zhang, Yaowen Chang, Shasha Wang, Weizhi He, Wenxia Sun, Dongrong Chen & Alastair I.H. Murchie
Pages: 1432-1442
Published online: 24 Oct 2020
AbstractforAminoglycoside riboswitch control of the expression of integron associated aminoglycoside resistance adenyltransferases | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
  • 1359 Views
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Article
Shorter incubation period is associated with severe disease progression in patients with COVID-19
Changxiang Lai, Rentao Yu, Mingbo Wang, Wenjie Xian, Xin Zhao, Qiyuan Tang, Ruikun Chen, Xuan Zhou, Xuan Li, Zhiyu Li, Zhiwei Li, Guohong Deng & Fang Wang
Pages: 1443-1452
Published online: 27 Oct 2020
AbstractforShorter incubation period is associated with severe disease progression in patients with COVID-19 | Full Text | References | PDF (424.8 KB) | EPUB
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Article
Candida albicans adhesion to central venous catheters: Impact of blood plasma-driven germ tube formation and pathogen-derived adhesins
Philipp Jung, Clara E. Mischo, Gubesh Gunaratnam, Christian Spengler, Sören L. Becker, Bernhard Hube, Karin Jacobs & Markus Bischoff
Pages: 1453-1465
Published online: 27 Oct 2020
AbstractforCandida albicans adhesion to central venous catheters: Impact of blood plasma-driven germ tube formation and pathogen-derived adhesins | Full Text | References | PDF (3.8 MB) | EPUB
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Article
Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs
Hassan E. Eldesouky, Nadia A. Lanman, Tony R. Hazbun & Mohamed N. Seleem
Pages: 1466-1481
Published online: 26 Oct 2020
AbstractforAprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 1839 Views
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Review Article

Review Article
Contribution of hypoxia inducible factor-1 during viral infections
Antonia Reyes, Nicolás Corrales, Nicolás M. S. Gálvez, Susan M. Bueno, Alexis M. Kalergis & Pablo A. González
Pages: 1482-1500
Published online: 31 Oct 2020
AbstractforContribution of hypoxia inducible factor-1 during viral infections | Full Text | References | PDF (6.3 MB) | EPUB
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Research Paper

Article
Altering retinol binding protein 4 levels in hepatitis C: Inflammation and steatosis matter
Ming-Ling Chang, Wei-Ting Chen, Jing-Hong Hu, Shiang-Chi Chen, Po-Wen Gu & Rong-Nan Chien
Pages: 1501-1511
Published online: 31 Oct 2020
AbstractforAltering retinol binding protein 4 levels in hepatitis C: Inflammation and steatosis matter | Full Text | References | PDF (7.3 MB) | EPUB
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Article
Parasitoid wasp venom vesicles (venosomes) enter Drosophila melanogaster lamellocytes through a flotillin/lipid raft-dependent endocytic pathway
Bin Wan, Marylène Poirié & Jean-Luc Gatti
Pages: 1512-1521
Published online: 31 Oct 2020
AbstractforParasitoid wasp venom vesicles (venosomes) enter Drosophila melanogaster lamellocytes through a flotillin/lipid raft-dependent endocytic pathway | Full Text | References | PDF (5.1 MB) | EPUB | Supplemental
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Article
A new regulator in the crossroads of oxidative stress resistance and virulence in Candida glabrata: The transcription factor CgTog1
Pedro Pais, Susana Vagueiro, Dalila Mil-Homens, Andreia I. Pimenta, Romeu Viana, Michiyo Okamoto, Hiroji Chibana, Arsénio M. Fialho & Miguel C. Teixeira
Pages: 1522-1538
Published online: 31 Oct 2020
AbstractforA new regulator in the crossroads of oxidative stress resistance and virulence in Candida glabrata: The transcription factor CgTog1 | Full Text | References | PDF (3.8 MB) | EPUB | Supplemental
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Article
YSIRK-G/S-directed translocation is required for Streptococcus suis to deliver diverse cell wall anchoring effectors contributing to bacterial pathogenicity
Qiankun Bai, Jiale Ma, Ze Zhang, Xiaojun Zhong, Zihao Pan, Yinchu Zhu, Yue Zhang, Zongfu Wu, Guangjin Liu & Huochun Yao
Pages: 1539-1556
Published online: 02 Nov 2020
AbstractforYSIRK-G/S-directed translocation is required for Streptococcus suis to deliver diverse cell wall anchoring effectors contributing to bacterial pathogenicity | Full Text | References | PDF (7.5 MB) | EPUB | Supplemental
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Article
Clinical characteristics of asymptomatic carriers of novel coronavirus disease 2019: A multi-center study in Jiangsu Province
Jiaxin Chen, Tao Han, Mao Huang, Yi Yang, Futai Shang, Yishan Zheng, Wenjing Zhao, Liang Luo, Xudong Han, Aihua Lin, Hongsheng Zhao, Qin Gu, Yi Shi, Jun Li, Xingxiang Xu, Kexi Liu, Yijun Deng, Enzhi Jia & Quan Cao
Pages: 1557-1568
Published online: 02 Nov 2020
AbstractforClinical characteristics of asymptomatic carriers of novel coronavirus disease 2019: A multi-center study in Jiangsu Province | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Novel biomarkers for the prediction of COVID-19 progression a retrospective, multi-center cohort study
Yalan Yu, Tao Liu, Liang Shao, Xinyi Li, Colin K. He, Muhammad Jamal, Yi Luo, Yingying Wang, Yanan Liu, Yufeng Shang, Yunbao Pan, Xinghuan Wang & Fuling Zhou
Pages: 1569-1581
Published online: 11 Nov 2020
AbstractforNovel biomarkers for the prediction of COVID-19 progression a retrospective, multi-center cohort study | Full Text | References | PDF (5.5 MB) | EPUB | Supplemental
  • 3064 Views
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Review Article

Review Article
Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions
Ansel Hsiao & Jun Zhu
Pages: 1582-1599
Published online: 11 Nov 2020
AbstractforPathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions | Full Text | References | PDF (2.2 MB) | EPUB
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Review Article
Pathogenicity & virulence of Mycoplasma hyopneumoniae
Fernanda M. A. Leal Zimmer, Jéssica Andrade Paes, Arnaldo Zaha & Henrique Bunselmeyer Ferreira
Pages: 1600-1622
Published online: 08 Dec 2020
AbstractforPathogenicity & virulence of Mycoplasma hyopneumoniae | Full Text | References | PDF (4.3 MB) | EPUB
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Article
Time-resolved analysis of Staphylococcus aureus invading the endothelial barrier
Elisa J.M. Raineri, Harita Yedavally, Anna Salvati & Jan Maarten van Dijl
Pages: 1623-1639
Published online: 22 Nov 2020
AbstractforTime-resolved analysis of Staphylococcus aureus invading the endothelial barrier | Full Text | References | PDF (8.4 MB) | EPUB | Supplemental
  • 1759 Views
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Article
Role of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection
Mario Perro, Matteo Iannacone, Ulrich H. von Andrian & Antonio Peixoto
Pages: 1640-1655
Published online: 29 Nov 2020
AbstractforRole of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection | Full Text | References | PDF (7.8 MB) | EPUB | Supplemental
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Article
Tissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency
Cecilia B. Korol, Shamira J. Shallom, Kriti Arora, Helena I. Boshoff, Alexandra F. Freeman, Alejandra King, Sonia Agrawal, Sean C. Daugherty, Timothy Jancel, Juraj Kabat, Sundar Ganesan, Marina N. Torrero, Elizabeth P. Sampaio, Clifton Barry III, Steve M Holland, Hervé Tettelin, Sergio D Rosenzweig & Adrian M. Zelazny
Pages: 1656-1673
Published online: 24 Dec 2020
AbstractforTissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
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Article
Pre-exposure to Candida glabrata protects Galleria mellonella against subsequent lethal fungal infections
Xiao-Wen Huang, Mei-Nian Xu, Huan-Xin Zheng, Meng-Lei Wang, Li Li, Kang Zeng & De-Dong Li
Pages: 1674-1684
Published online: 29 Nov 2020
AbstractforPre-exposure to Candida glabrata protects Galleria mellonella against subsequent lethal fungal infections | Full Text | References | PDF (4.2 MB) | EPUB | Supplemental
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Article
MoSec61β, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae
Yun-Yun Wei, Shuang Liang, Yun-Ran Zhang, Jian-Ping Lu, Fu-Cheng Lin & Xiao-Hong Liu
Pages: 1685-1700
Published online: 29 Nov 2020
AbstractforMoSec61β, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae | Full Text | References | PDF (15 MB) | EPUB | Supplemental
  • 1981 Views
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Article
The outer-membrane protein MafA of Neisseria meningitidis constitutes a novel protein secretion pathway specific for the fratricide protein MafB
Jesús Arenas, Laura Catón, Tom van den Hoeven, Vincent de Maat, Juan Cruz Herrero & Jan Tommassen
Pages: 1701-1715
Published online: 14 Dec 2020
AbstractforThe outer-membrane protein MafA of Neisseria meningitidis constitutes a novel protein secretion pathway specific for the fratricide protein MafB | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
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Article
Roles of the Hcp family proteins in the pathogenicity of Salmonella typhimurium 14028s
Ping Wang, Jun-Fang Dong, Ren-Qing Li, Lei Li & Qing-Hua Zou
Pages: 1716-1726
Published online: 10 Dec 2020
AbstractforRoles of the Hcp family proteins in the pathogenicity of Salmonella typhimurium 14028s | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1707 Views
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Article
Virulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii
Gema Labrador-Herrera, Antonio J. Pérez-Pulido, Rocío Álvarez-Marín, Carlos S. Casimiro-Soriguer, Tania Cebrero-Cangueiro, Jorgelina Morán-Barrio, Jerónimo Pachón, Alejandro M. Viale & María Eugenia Pachón-Ibáñez
Pages: 1727-1737
Published online: 10 Dec 2020
AbstractforVirulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 1791 Views
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Article
SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1
Aura M. Ramirez, Karen E. Beenken, Stephanie D. Byrum, Alan J. Tackett, Lindsey N. Shaw, Brittney D. Gimza & Mark S. Smeltzer
Pages: 1738-1762
Published online: 14 Dec 2020
AbstractforSarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1 | Full Text | References | PDF (4 MB) | EPUB | Supplemental
  • 1889 Views
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