Biotechnology & Biotechnological Equipment, Volume 36, Issue 1 (2022)

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Biotechnology & Biotechnological Equipment, Volume 36, Issue 1 (2022)

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Review

Review
Organic dyes in contemporary medicinal chemistry and biomedicine. I. From the chromophore to the bioimaging/bioassay agent
Zvezdelina Yaneva, Donika Ivanova, Nevena Nikolova & Monika Toneva
Pages: 1-14
Published online: 21 Mar 2022
AbstractforOrganic dyes in contemporary medicinal chemistry and biomedicine. I. From the chromophore to the bioimaging/bioassay agent | Full Text | References | PDF (1.2 MB) | EPUB
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Articles

Article
Toxicity and degradation of 2,4,6-trinitrotoluene in transgenic Arabidopsis expressing Citrobacter freundii nitroreductase
Bo Zhu, Xiyan Hu, Shuanghong You, Jianjie Gao, Xiaoyan Fu, Hongjuan Han, Zhenjun Li & Quanhong Yao
Pages: 15-24
Published online: 21 Mar 2022
AbstractforToxicity and degradation of 2,4,6-trinitrotoluene in transgenic Arabidopsis expressing Citrobacter freundii nitroreductase | Full Text | References | PDF (2.8 MB) | EPUB
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Article
Comparative retrotransposon analysis of mutant and non-mutant rice varieties grown at different salt concentrations
Yunus Emre Arvas, İsmail Kocaçalışkan, Emel Ordu & Semiha Erişen
Pages: 25-34
Published online: 30 Mar 2022
AbstractforComparative retrotransposon analysis of mutant and non-mutant rice varieties grown at different salt concentrations | Full Text | References | PDF (1,001.3 KB) | EPUB
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Article
Hyperglycemia attenuates fibroblast contractility via suppression of TβRII receptor modulated α-smooth muscle actin expression
Alexandar Evangelatov, Georgi Georgiev, Borislav Arabadjiev, Stefan Pankov, Plamen Krastev, Albena Momchilova & Roumen Pankov
Pages: 35-44
Published online: 21 Mar 2022
AbstractforHyperglycemia attenuates fibroblast contractility via suppression of TβRII receptor modulated α-smooth muscle actin expression | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Ethanolic extract of Turkish bee pollen and propolis: phenolic composition, antiradical, antiproliferative and antibacterial activities
Hatice Ahu Kahraman, Hidayet Tutun, Muhammet Mükerrem Kaya, Melike Sultan Usluer, Soner Tutun, Ceren Yaman, Sedat Sevin & Erhan Keyvan
Pages: 45-56
Published online: 21 Mar 2022
AbstractforEthanolic extract of Turkish bee pollen and propolis: phenolic composition, antiradical, antiproliferative and antibacterial activities | Full Text | References | PDF (1 MB) | EPUB
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Article
Effect of mobile phone usage duration during pregnancy on the general motor movements of infants
Hava Bektas, Mehmet Selcuk Bektas & Suleyman Dasdag
Pages: 57-67
Published online: 22 Mar 2022
AbstractforEffect of mobile phone usage duration during pregnancy on the general motor movements of infants | Full Text | References | PDF (675.5 KB) | EPUB
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Article
Assaying for antiviral activity of the folkloric medicinal desert plant Rhazya stricta on coronavirus SARS-CoV-2
Mohammed N. Baeshen, Roba Attar, Thamer A. Bouback, Abdulaziz O. Albeshri, Naseebh N. Baeshen, Alaa Karkashan, Basma Abbas, Abdullah A. Aljaddawi, Yaaser Q. Almulaiky, Sara H. Mahmoud, Noura M. Abo Shama, Mohamed A. Ali, Moayad Baadhaim, Samer Zakri, Khaled Alsayegh, Arif Mohammed & Nabih A. Baeshen
Pages: 68-74
Published online: 21 Mar 2022
AbstractforAssaying for antiviral activity of the folkloric medicinal desert plant Rhazya stricta on coronavirus SARS-CoV-2 | Full Text | References | PDF (1,012 KB) | EPUB
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Article
Pituitary apoplexy associated with COVID-19 infection: review and a case report
Deyan Popov & Asen Hadzhiyanev
Pages: 75-81
Published online: 04 Apr 2022
AbstractforPituitary apoplexy associated with COVID-19 infection: review and a case report | Full Text | References | PDF (820.6 KB) | EPUB
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Review

Review
Recent advances and future prospects in topical creams from medicinal plants to expedite wound healing: a review
Iliyasu Datti Gwarzo, Siti Pauliena Mohd Bohari, Roswanira Abdul Wahab & Arifullah Zia
Pages: 82-94
Published online: 01 Apr 2022
AbstractforRecent advances and future prospects in topical creams from medicinal plants to expedite wound healing: a review | Full Text | References | PDF (1.5 MB) | EPUB
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Article

Article
Decolourization of synthetic dyes by laccase produced from Bacillus sp. NU2
Chiedu Epiphany Edoamodu & Uchechukwu Uchechukwu Nwodo
Pages: 95-106
Published online: 23 Mar 2022
AbstractforDecolourization of synthetic dyes by laccase produced from Bacillus sp. NU2 | Full Text | References | PDF (1.3 MB) | EPUB
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Reviews

Review
Enhancing precision medicine through clinical mass spectrometry platform
Julieta Hristova & Dobrin Svinarov
Pages: 107-117
Published online: 23 Mar 2022
AbstractforEnhancing precision medicine through clinical mass spectrometry platform | Full Text | References | PDF (749.5 KB) | EPUB
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Review
State of the art and applications in nanostructured biocatalysis
Fengfan Liu, Zhihao Shi, Weike Su & Jiequn Wu
Pages: 118-134
Published online: 23 Mar 2022
AbstractforState of the art and applications in nanostructured biocatalysis | Full Text | References | PDF (1.7 MB) | EPUB
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Articles

Article
Two QTL for kernel number per spike identified from durum wheat
Jingtian Yang, Zhengqiao Liao, Baoguo Du, Kuan Zhang & Lei Liu
Pages: 135-141
Published online: 23 Mar 2022
AbstractforTwo QTL for kernel number per spike identified from durum wheat | Full Text | References | PDF (947.8 KB) | EPUB | Supplemental
  • 779 Views
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Article
Comparative study on the metabolic behaviour of anode biofilm in microbial fuel cell under different external resistance
Yana Mersinkova, Hyusein Yemendzhiev & Valentin Nenov
Pages: 142-147
Published online: 23 Mar 2022
AbstractforComparative study on the metabolic behaviour of anode biofilm in microbial fuel cell under different external resistance | Full Text | References | PDF (594.8 KB) | EPUB
  • 1187 Views
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Article
Structure and features of the complete chloroplast genome of Salix triandroides (Salicaceae)
Xiaoxing Zhou, Shihong Sheng, Qi Xu, Rihui Lu, Chuan Chen, Huiming Peng & Chen Feng
Pages: 148-158
Published online: 20 Apr 2022
AbstractforStructure and features of the complete chloroplast genome of Salix triandroides (Salicaceae) | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
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Article
Induction of gene silencing of NIb gene region of Potato virus Y by dsRNAs and siRNAs and reduction of infection in potato plants cultivar Djeli
Nikolay Manchev Petrov, Mariya Ivanova Stoyanova, Antoniy Vasilev Stoev & Rajarshi Kumar Gaur
Pages: 159-164
Published online: 11 Apr 2022
AbstractforInduction of gene silencing of NIb gene region of Potato virus Y by dsRNAs and siRNAs and reduction of infection in potato plants cultivar Djeli | Full Text | References | PDF (546.5 KB) | EPUB
  • 1092 Views
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Article
What food will we be eating on our journey to Mars?
Krzysztof Lewandowski & Aleksandra Stryjska
Pages: 165-175
Published online: 13 Apr 2022
AbstractforWhat food will we be eating on our journey to Mars? | Full Text | References | PDF (773.4 KB) | EPUB
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Article
Expression analysis of squalene synthase gene in mevalonate pathway of Sanghuangporus baumii
Shixin Wang, Xutong Wang, Zengcai Liu, Tingting Sun & Li Zou
Pages: 176-183
Published online: 10 Apr 2022
AbstractforExpression analysis of squalene synthase gene in mevalonate pathway of Sanghuangporus baumii | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 1083 Views
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Article
Genetic analysis of yield and yield contributing traits in rice (Oryza sativa L.) BC2F3 population derived from MR264 × PS2
Nor’Aishah Hasan, Mohd Yusop Rafii, Abdul Rahim Harun, Nusaibah Syed Alı, Norida Mazlan & Shamsiah Abdullah
Pages: 184-192
Published online: 10 Apr 2022
AbstractforGenetic analysis of yield and yield contributing traits in rice (Oryza sativa L.) BC2F3 population derived from MR264 × PS2 | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
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Article
Clinical and radiological findings, SEM analysis and evaluation of caries risk in ectodermal dysplasia cases
Yasemin Yavuz, Ebru Akleyin, Mehmet Zülküf Akdağ, Mehmet Çolak, Mehmet Sinan Doğan & Sedef Kotanlı
Pages: 193-199
Published online: 11 Apr 2022
AbstractforClinical and radiological findings, SEM analysis and evaluation of caries risk in ectodermal dysplasia cases | Full Text | References | PDF (1.5 MB) | EPUB
  • 988 Views
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Article
Specific alterations in mucosa-associated bacterial composition in ulcerative colitis (UC) patients with different degrees of inflammation
Yansheng Shang, Zhenzhen Zhai, Jiaguo Huang, Lixiang Li & Xiuli Zuo
Pages: 200-208
Published online: 27 Apr 2022
AbstractforSpecific alterations in mucosa-associated bacterial composition in ulcerative colitis (UC) patients with different degrees of inflammation | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Diversity of nirS and nirK denitrifying bacteria in rhizosphere and non-rhizosphere soils of halophytes in Ebinur Lake Wetland
Yanhui Niu, Wenge Hu, Tingting Zhou, Bo He, Xuemei Chen & Yang Li
Pages: 209-219
Published online: 01 May 2022
AbstractforDiversity of nirS and nirK denitrifying bacteria in rhizosphere and non-rhizosphere soils of halophytes in Ebinur Lake Wetland | Full Text | References | PDF (1 MB) | EPUB | Supplemental
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Article
Adaptation of micro- and metafauna in activated sludge with microbial augmentation to shock loading with amaranth
Ivaylo Dimitrov Yotinov, Mihaela Vladimirova Belouhova, Nora Kirilova Dinova, Yovana Todorova Todorova, Irina Dietmar Schneider & Yana Ilieva Topalova
Pages: 220-231
Published online: 01 May 2022
AbstractforAdaptation of micro- and metafauna in activated sludge with microbial augmentation to shock loading with amaranth | Full Text | References | PDF (1.6 MB) | EPUB
  • 1098 Views
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Article
Identification and expression analysis of capsaicin biosynthesis pathway genes at genome level in Capsicum chinense
Wei Zhang, Dan Wu, Liping Zhang, Chengzhi Zhao, Huangying Shu, Shanhan Cheng, Zhiwei Wang, Jie Zhu & Pingwu Liu
Pages: 232-244
Published online: 31 May 2022
AbstractforIdentification and expression analysis of capsaicin biosynthesis pathway genes at genome level in Capsicum chinense | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 2499 Views
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Article
Investigation of soil microbiota reveals variable dominant species at different land areas in China
Hai Liu, Shan Jiang, Jintao Ou, Jinfeng Tang, Yang Lu & Yongjun Wei
Pages: 245-255
Published online: 08 May 2022
AbstractforInvestigation of soil microbiota reveals variable dominant species at different land areas in China | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1356 Views
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Article
Evaluation of advanced protein oxidation and RAGE gene variants in the risk of laryngeal cancer
Ozlem Kucukhuseyin, Karolin Yanar, Mehmet Tolgahan Hakan, Aysegul Verim, Yusufhan Suoglu, Pinar Atukeren, Seval Aydin, Ufuk Cakatay, Hulya Yılmaz Aydogan & Ilhan Yaylim
Pages: 256-267
Published online: 09 May 2022
AbstractforEvaluation of advanced protein oxidation and RAGE gene variants in the risk of laryngeal cancer | Full Text | References | PDF (871.6 KB) | EPUB
  • 858 Views
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Article
Genome-wide identification and expression analysis of tomato glycoside hydrolase family 1 β-glucosidase genes in response to abiotic stresses
Jinpeng Wei, Qiusen Chen, Jiaxin Lin, Fengqiong Chen, Runan Chen, Hanlin Liu, Peiyu Chu, Zhiyong Lu, Shaozhe Li & Gaobo Yu
Pages: 268-280
Published online: 18 May 2022
AbstractforGenome-wide identification and expression analysis of tomato glycoside hydrolase family 1 β-glucosidase genes in response to abiotic stresses | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 1601 Views
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Article
Fermentation medium optimization, molecular modelling and docking analysis of the alginate lyase of a novel Pseudomonas sp. LB56 isolated from seaweed waste
Bidyut Ranjan Mohapatra
Pages: 281-291
Published online: 10 May 2022
AbstractforFermentation medium optimization, molecular modelling and docking analysis of the alginate lyase of a novel Pseudomonas sp. LB56 isolated from seaweed waste | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 1356 Views
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Article
Campylobacter infection in children and adults in Bulgaria: comparative characteristics and antimicrobial resistance
Valeri Velev, Maria Pavlova, Ekaterina Alexandrova, Ivan Ivanov & Metodi Popov
Pages: 292-298
Published online: 10 May 2022
AbstractforCampylobacter infection in children and adults in Bulgaria: comparative characteristics and antimicrobial resistance | Full Text | References | PDF (693.4 KB) | EPUB
  • 768 Views
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Article
The role of angio-optical coherent tomography in the surgical management of the vitreoretinal interface
Aleksandrina Tsenova Gatseva, Irina Kuneva, Monika Dimitrova & Boryana Mihaylova Irinkova
Pages: 299-304
Published online: 11 May 2022
AbstractforThe role of angio-optical coherent tomography in the surgical management of the vitreoretinal interface | Full Text | References | PDF (746.3 KB) | EPUB
  • 588 Views
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Review

Review
Aquaponic systems: biological and technological parameters
Milena Krastanova, Ivo Sirakov, Sofiya Ivanova-Kirilova, Dobry Yarkov & Petya Orozova
Pages: 305-316
Published online: 11 May 2022
AbstractforAquaponic systems: biological and technological parameters | Full Text | References | PDF (972 KB) | EPUB
  • 12996 Views
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Articles

Article
Functional characterization of Medicago truncatula GRAS7, a member of the GRAS family transcription factors, in response to abiotic stress
Miglena Revalska, Mariana Radkova & Anelia Iantcheva
Pages: 317-326
Published online: 11 May 2022
AbstractforFunctional characterization of Medicago truncatula GRAS7, a member of the GRAS family transcription factors, in response to abiotic stress | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 995 Views
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Article
Intratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancer Immune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and colorectal cancer development
Maya Vladova Gulubova, Dimitur Chavdarov Chonov, Koni Vancho Ivanova, Mariyna Kostova Hristova, Maria Magdalena Krasimirova-Ignatova & Tatyana Ivanova Vlaykova
Pages: 327-338
Published online: 14 May 2022
AbstractforIntratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancer Immune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and colorectal cancer development | Full Text | References | PDF (1.1 MB) | EPUB
  • 984 Views
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Article
Detection of chicken adulteration in beef via ladder-shape melting temperature isothermal amplification (LMTIA) assay
Yongzhen Wang, Borui Wang & Deguo Wang
Pages: 339-345
Published online: 26 May 2022
AbstractforDetection of chicken adulteration in beef via ladder-shape melting temperature isothermal amplification (LMTIA) assay | Full Text | References | PDF (1.3 MB) | EPUB
  • 975 Views
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Article
Analgesic efficacy of preoperative ultrasound transversal abdominal plane block for open hysterectomy
Georgi Penev & Evgeni Grigorov
Pages: 346-352
Published online: 26 May 2022
AbstractforAnalgesic efficacy of preoperative ultrasound transversal abdominal plane block for open hysterectomy | Full Text | References | PDF (1,010.1 KB) | EPUB
  • 799 Views
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Article
Gene silencing of VP1 gene of coxsackievirus B3 neurotropic strain Nancy by dsRNAs and siRNAs
Nikolay Petrov, Mariya Stoyanova, Adelina Stoyanova, Ivanka Nikolova, Petar Grozdanov & Angel Galabov
Pages: 353-361
Published online: 02 Jun 2022
AbstractforGene silencing of VP1 gene of coxsackievirus B3 neurotropic strain Nancy by dsRNAs and siRNAs | Full Text | References | PDF (761.7 KB) | EPUB
  • 757 Views
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Article
Impact of CYP3A7, CYP2D6 and ABCC2/ABCC3 polymorphisms on tacrolimus steady state concentrations in Bulgarian kidney transplant recipients
Tsvetelin Lukanov, Milena Ivanova, Petya Yankova, Bushra Al Hadra, Anastasiya Mihaylova, Marianka Genova, Dobrin Svinarov & Elisaveta Naumova
Pages: 362-369
Published online: 31 May 2022
AbstractforImpact of CYP3A7, CYP2D6 and ABCC2/ABCC3 polymorphisms on tacrolimus steady state concentrations in Bulgarian kidney transplant recipients | Full Text | References | PDF (589.2 KB) | EPUB
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Article
Dicer induced reactive oxygen species inhibit hepatocellular carcinoma through interacting with cytochrome c oxidase
Lin Hou, Na Xing, Zhao Yue, Jianhua Wu, Fujun Wang & Zhanjun Guo
Pages: 370-378
Published online: 31 May 2022
AbstractforDicer induced reactive oxygen species inhibit hepatocellular carcinoma through interacting with cytochrome c oxidase | Full Text | References | PDF (1 MB) | EPUB
  • 791 Views
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Article
Microbial functional diversity in rhizosphere and non-rhizosphere soil of different dominant species in a vegetation concrete slope
Lu Xia, Bin Qing Zhao, Ting Luo, Wennian Xu, Ting Guo & Dong Xia
Pages: 379-388
Published online: 03 Jun 2022
AbstractforMicrobial functional diversity in rhizosphere and non-rhizosphere soil of different dominant species in a vegetation concrete slope | Full Text | References | PDF (830.3 KB) | EPUB
  • 1867 Views
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Article
Transcriptome data mining towards characterization of single nucleotide polymorphisms (SNPs) controlling salinity tolerance in bread wheat
Ahmed Karam, Salah El-Din Sayed El-Assal, Basita Abbas Hussein & Mohamed Atia Mohamed Atia
Pages: 389-400
Published online: 07 Jun 2022
AbstractforTranscriptome data mining towards characterization of single nucleotide polymorphisms (SNPs) controlling salinity tolerance in bread wheat | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 1703 Views
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Article
Improved drought tolerance in soybean by protein elicitor AMEP412 induced ROS accumulation and scavenging
Quan Liu, Siwen Wang, Yanli Du & Kuide Yin
Pages: 401-412
Published online: 23 Jun 2022
AbstractforImproved drought tolerance in soybean by protein elicitor AMEP412 induced ROS accumulation and scavenging | Full Text | References | PDF (1.8 MB) | EPUB
  • 734 Views
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Article
Cerebral vasospasm after subarachnoid hemorrhage from intracranial aneurysm rupture in SARS-CoV-2 positive patients. A retrospective review from two Bulgarian hospitals
Dimitar Monov, Nikolay Lilyanov, Stefan Bogovsky, Kristina Sirakova & Dimitar Nikolakov
Pages: 413-417
Published online: 23 Jun 2022
AbstractforCerebral vasospasm after subarachnoid hemorrhage from intracranial aneurysm rupture in SARS-CoV-2 positive patients. A retrospective review from two Bulgarian hospitals | Full Text | References | PDF (413.6 KB) | EPUB
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Article
C-peptide levels and glycemic indices in COVID-19 patients
Ralitsa Robeva, Daniela Petrova, Atanaska Elenkova, Tsvetalina Tankova & Sabina Zacharieva
Pages: 418-424
Published online: 25 Jun 2022
AbstractforC-peptide levels and glycemic indices in COVID-19 patients | Full Text | References | PDF (598 KB) | EPUB
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Article
Autologous ovarian platelet rich plasma treatment improves oocyte and embryo quality: a before-after prospective study
Dimitar Parvanov, Rumiana Ganeva, Nina Vidolova, Kristina Nikolova, Magdalena Vasileva, Tihomir Totev & Georgi Stamenov
Pages: 425-432
Published online: 29 Jun 2022
AbstractforAutologous ovarian platelet rich plasma treatment improves oocyte and embryo quality: a before-after prospective study | Full Text | References | PDF (869.5 KB) | EPUB
  • 3010 Views
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Article
Protein engineering of CMP kinases to improve thermal stability and resultant production of 3′-sialyllactose
Jingjing Wang, Jinyong Wu, Zhongkui Li, Xiangsong Chen, Weiwei Liu & Jianming Yao
Pages: 433-441
Published online: 05 Jul 2022
AbstractforProtein engineering of CMP kinases to improve thermal stability and resultant production of 3′-sialyllactose | Full Text | References | PDF (1.5 MB) | EPUB
  • 749 Views
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Article
Optimization of succinic acid production from xylose mother liquor (XML) by Actinobacillus succinogenes using response surface methodology
Naikun Shen, Shiyong Li, Yan Qin, Mingguo Jiang & Hongyan Zhang
Pages: 442-450
Published online: 05 Jul 2022
AbstractforOptimization of succinic acid production from xylose mother liquor (XML) by Actinobacillus succinogenes using response surface methodology | Full Text | References | PDF (1 MB) | EPUB
  • 787 Views
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Article
The wheat (Triticum aestiveum L.) MADS-box transcription factor TaMADS32 plays a role in response to abiotic stresses
Xuemei Zhang, Ting Li, Huangxin Chen, Huaping Tang, Yang Mu, Lulu Gou, Ahsan Habib, Xiujin Lan & Jian Ma
Pages: 451-461
Published online: 12 Jul 2022
AbstractforThe wheat (Triticum aestiveum L.) MADS-box transcription factor TaMADS32 plays a role in response to abiotic stresses | Full Text | References | PDF (1.2 MB) | EPUB
  • 873 Views
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Article
An appropriate unstructured kinetic model describing the batch fermentation growth of Debaryomyces hansenii for xylitol production using hydrolysis of oil palm empty fruit bunch
Kasbawati Kasbawati, Efri Mardawati, Rusni Samsir, Sri Suhartini & Anisa Kalondeng
Pages: 462-471
Published online: 14 Jul 2022
AbstractforAn appropriate unstructured kinetic model describing the batch fermentation growth of Debaryomyces hansenii for xylitol production using hydrolysis of oil palm empty fruit bunch | Full Text | References | PDF (1.5 MB) | EPUB
  • 1298 Views
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Article
Transcriptome analysis for genes involved in fructan biosynthesis in the Jerusalem artichoke (Helianthus tuberosus L.)
Ying Wang, Gui Wang, Zhenjie Zhou, Yuan Zong, Lihui Wang, Shipeng Yang, Yaqi Zhang & Xuemei Sun
Pages: 472-480
Published online: 29 Aug 2022
AbstractforTranscriptome analysis for genes involved in fructan biosynthesis in the Jerusalem artichoke (Helianthus tuberosus L.) | Full Text | References | PDF (1.4 MB) | EPUB
  • 778 Views
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Article
Quality of life, control of treatment and satisfaction of patients with asthma in Bulgaria: a pilot study
Miglena Doneva, Petya Milushewa, Maria Dimitrova, Maria Kamusheva, Jordan Stoitchkov, Guenka Petrova, Kremena Naydenova, Borislava Krusheva, Vasil Dimitrov & Dragana Lakic
Pages: 481-488
Published online: 20 Jul 2022
AbstractforQuality of life, control of treatment and satisfaction of patients with asthma in Bulgaria: a pilot study | Full Text | References | PDF (1.1 MB) | EPUB
  • 818 Views
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Article
Design, synthesis and evaluation of semi- and thiosemicarbazides containing a methylxanthine moiety with in vitro neuroprotective and MAO-B inhibitory activities
Javor Mitkov, Magdalena Kondeva-Burdina, Lily Peikova, Maya Georgieva & Alexander Zlatkov
Pages: 489-502
Published online: 23 Jul 2022
AbstractforDesign, synthesis and evaluation of semi- and thiosemicarbazides containing a methylxanthine moiety with in vitro neuroprotective and MAO-B inhibitory activities | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 881 Views
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Article
Analysis and characterization of the chloroplast genome of Stephania cepharantha Hayata
Xinran Li, Qingyan Zhang, Guiying Weng, Miao Zhu & Xuying Wang
Pages: 503-512
Published online: 20 Jul 2022
AbstractforAnalysis and characterization of the chloroplast genome of Stephania cepharantha Hayata | Full Text | References | PDF (1.5 MB) | EPUB
  • 815 Views
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Article
Genetic mapping of QTL for three root-related traits in wheat (Triticum aestivum)
Li Li, Zhigui Liu & Jun Wu
Pages: 513-519
Published online: 19 Jul 2022
AbstractforGenetic mapping of QTL for three root-related traits in wheat (Triticum aestivum) | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 898 Views
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Article
Internalization of myriocin involved in energy and affected expression of genes and proteins in the endocytosis pathway in Fusarium oxysporum f. sp. niveum
Shiqi Luo, Hengxu Wang, Zhigang Wang, Weihui Xu, Renmao Tian & Jiaxin Zhou
Pages: 520-532
Published online: 20 Jul 2022
AbstractforInternalization of myriocin involved in energy and affected expression of genes and proteins in the endocytosis pathway in Fusarium oxysporum f. sp. niveum | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
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Article
Bio-enhanced contact oxidation process using a heterotrophic nitrifying-aerobic denitrifying strain
Yangyue Zhan, Bin Zhang, Jia Xie & Wei Liu
Pages: 533-544
Published online: 20 Jul 2022
AbstractforBio-enhanced contact oxidation process using a heterotrophic nitrifying-aerobic denitrifying strain | Full Text | References | PDF (2.3 MB) | EPUB
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Article
Bicistronic vector-based procedure to measure correlative expression and bacteriostatic activity of recombinant neutrophil gelatinase-associated lipocalin
Somphot Saoin, Naphatswan Arunyanak, Pornuma Muangchan, Chatikorn Boonkrai, Trairak Pisitkun, Chiraphat Kloypan & Sawitree Nangola
Pages: 545-552
Published online: 08 Sep 2022
AbstractforBicistronic vector-based procedure to measure correlative expression and bacteriostatic activity of recombinant neutrophil gelatinase-associated lipocalin | Full Text | References | PDF (872.5 KB) | EPUB
  • 562 Views
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Article
Transcriptome analysis identifies key genes involved in anthocyanin biosynthesis in black and purple fruits (Lycium ruthenicum Murr. L)
Xuemei Bao, Xiaolong Gan, Guanghui Fan, Guangrui Liu, Xiaolin Ma, Baolong Liu & Yuan Zong
Pages: 553-560
Published online: 08 Sep 2022
AbstractforTranscriptome analysis identifies key genes involved in anthocyanin biosynthesis in black and purple fruits (Lycium ruthenicum Murr. L) | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Article
Arabidopsis sucrose transporter 4 (AtSUC4) is involved in high sucrose-mediated inhibition of root elongation
Siwen Liu, Jianmei Long, Liding Zhang, Jiayu Gao, Tiantian Dong, Ying Wang & Changcao Peng
Pages: 561-574
Published online: 08 Sep 2022
AbstractforArabidopsis sucrose transporter 4 (AtSUC4) is involved in high sucrose-mediated inhibition of root elongation | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
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Article
Genome-wide identification, phylogeny and expression analyses of group III WRKY genes in cotton (Gossypium hirsutum)
Lijun Dong, Meng Wang, Xue Zhang, Jianfeng Liu & Shuling Zhang
Pages: 575-586
Published online: 08 Sep 2022
AbstractforGenome-wide identification, phylogeny and expression analyses of group III WRKY genes in cotton (Gossypium hirsutum) | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
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Article
Identification and quantification of anthocyanins of 62 blueberry cultivars via UPLC-MS
Silu Wang, Bowei Wang, Kun Dong, Jing Li, Yadong Li & Haiyue Sun
Pages: 587-597
Published online: 12 Sep 2022
AbstractforIdentification and quantification of anthocyanins of 62 blueberry cultivars via UPLC-MS | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Article
Combinations of mild chemical and bacterial pretreatment for improving enzymatic saccharification of corn stover
Guoqing Liu, Dongjing Han & Shaohua Yang
Pages: 598-608
Published online: 10 Sep 2022
AbstractforCombinations of mild chemical and bacterial pretreatment for improving enzymatic saccharification of corn stover | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
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Article
Identification and estimation of sequence variation dynamics of Tomato Leaf curl Palampur virus and betasatellite complex infecting a new weed host
Muhammad Naeem Sattar, Muhammad Khurshid, Hossam S. El-Beltagi & Zafar Iqbal
Pages: 609-619
Published online: 08 Sep 2022
AbstractforIdentification and estimation of sequence variation dynamics of Tomato Leaf curl Palampur virus and betasatellite complex infecting a new weed host | Full Text | References | PDF (1.5 MB) | EPUB
  • 853 Views
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Article
Identification of Cladosporium fulvum infection responsive genes in tomato through cDNA-AFLP
Guan Liu, Dongye Zhang, Tingting Zhao, Huanhuan Yang, Jingbin Jiang, Jingfu Li, He Zhang, Xiangyang Xu & Xiaohang Hu
Pages: 620-630
Published online: 08 Sep 2022
AbstractforIdentification of Cladosporium fulvum infection responsive genes in tomato through cDNA-AFLP | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 787 Views
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Article
Inhibitory effect of pentoxifylline on the synthesis and deposition of glycosaminoglycans in hypothyroid skin
Georgeta Bocheva, Lina Malinova, Dimitar Bakalov, Georgi Bogdanov, Julieta Hristova & Dobrin Svinarov
Pages: 631-636
Published online: 08 Sep 2022
AbstractforInhibitory effect of pentoxifylline on the synthesis and deposition of glycosaminoglycans in hypothyroid skin | Full Text | References | PDF (1.2 MB) | EPUB
  • 578 Views
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Article
Genetic diversity and population structure of modern Bulgarian and foreign durum wheat based on microsatellite and agronomic data
Nikolai Kirilov Christov, Stefan Tsonev, Rangel Dragov, Krasimira Taneva, Violeta Bozhanova & Elena Georgieva Todorovska
Pages: 637-652
Published online: 08 Sep 2022
AbstractforGenetic diversity and population structure of modern Bulgarian and foreign durum wheat based on microsatellite and agronomic data | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 1164 Views
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Article
Analysis on bacterial community structure of new and old fermented pit mud of Shedian Liquor
Yanbo Liu, Mingyue Xu, Zhijun Zhao, Junyi Wu, Xian Wang, Xiyu Sun, Suna Han & Chunmei Pan
Pages: 653-661
Published online: 08 Sep 2022
AbstractforAnalysis on bacterial community structure of new and old fermented pit mud of Shedian Liquor | Full Text | References | PDF (1.1 MB) | EPUB
  • 626 Views
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Article
Relationship between smoking and periodontal clinical findings and gene expression of IL-6 and TNF-α in severe periodontitis (clinical and laboratory data)
Velitchka Dosseva-Panova, Zdravka Pashova-Tasseva & Antoaneta Mlachkova
Pages: 662-667
Published online: 08 Sep 2022
AbstractforRelationship between smoking and periodontal clinical findings and gene expression of IL-6 and TNF-α in severe periodontitis (clinical and laboratory data) | Full Text | References | PDF (486.4 KB) | EPUB
  • 839 Views
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Review

Review
Research advance and clinical implication of circZNF609 in human diseases
Jieyi Luo, Shengchun Wang, Lu Zhang, Lu Zhang, Shanshan Wu, Weirang Zheng, Xueshan Huang, Xiaoxia Ye & Minhua Wu
Pages: 668-683
Published online: 08 Sep 2022
AbstractforResearch advance and clinical implication of circZNF609 in human diseases | Full Text | References | PDF (1.7 MB) | EPUB
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Article

Article
Transcriptome analysis of strawberry (Fragaria × ananasa) responsive to Colletotrichum gloeosporioides inoculation and mining of resistance genes
Wenwei Liang, Mingjie Wang, Binghao Du, Lei Ling, Yingdong Bi, Jinghua Zhang, Yimin Sun, Shuang Zhou, Lili Zhang, Xiao Ma, Jun Ma, Liren Wu & Changhong Guo
Pages: 684-696
Published online: 08 Sep 2022
AbstractforTranscriptome analysis of strawberry (Fragaria × ananasa) responsive to Colletotrichum gloeosporioides inoculation and mining of resistance genes | Full Text | References | PDF (2.5 MB) | EPUB | Supplemental
  • 1069 Views
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Review

Review
The concept for the antivirulence therapeutics approach as alternative to antibiotics: hope or still a fiction?
Stoyanka Stoitsova, Tsvetelina Paunova-Krasteva, Petya D. Dimitrova & Tsvetozara Damyanova
Pages: 697-705
Published online: 08 Sep 2022
AbstractforThe concept for the antivirulence therapeutics approach as alternative to antibiotics: hope or still a fiction? | Full Text | References | PDF (962.5 KB) | EPUB
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Article

Article
Effects of salt stress on sucrose metabolism and growth in Chinese rose (Rosa chinensis)
Caihua Li, Yuhuan Li, Peiyu Chu, Zhao Hao-hao, Zunmiao Wei, Yan Cheng, Xianxian Liu, Fengzhou Zhao, Yan-jun Li, Zhiwen Zhang, Yi Zheng & Zhongsheng Mu
Pages: 706-716
Published online: 08 Sep 2022
AbstractforEffects of salt stress on sucrose metabolism and growth in Chinese rose (Rosa chinensis) | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 1323 Views
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Review

Review
35-bp deletion in ABCG2 gene: mini-review and report on two herds of Bulgarian dairy synthetic population sheep breed
Milena Bozhilova-Sakova, Ivona Dimitrova, Nevyana Stancheva, Maya Ignatova & Tanya Ivanova
Pages: 717-723
Published online: 08 Sep 2022
Abstractfor35-bp deletion in ABCG2 gene: mini-review and report on two herds of Bulgarian dairy synthetic population sheep breed | Full Text | References | PDF (493.6 KB) | EPUB
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Articles

Article
The common bean (Phaseolus vulgaris) SULTR gene family: genome-wide identification, phylogeny, evolutionary expansion and expression patterns
Qiang Zhao, Jing Geng, Yanli Du, Siqi Li, Xiankai Yuan, Jixing Zhu, Zhiheng Zhou, Qi Wang & Jidao Du
Pages: 724-736
Published online: 08 Sep 2022
AbstractforThe common bean (Phaseolus vulgaris) SULTR gene family: genome-wide identification, phylogeny, evolutionary expansion and expression patterns | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
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Article
Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study
Janet Kirilova, Dimitar Kirov, Dimitar Yovchev, Snezhanka Topalova-Pirinska & Elitsa Deliverska
Pages: 737-744
Published online: 08 Sep 2022
AbstractforEndodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study | Full Text | References | PDF (965.2 KB) | EPUB
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Article
Time-course RNA-seq analysis provides an improved understanding of genetic regulation in response to cold stress from white clover (Trifolium repens L.)
Xueqi Zhang, Huanhuan Yang, Manman Li, Chao Chen, Yan Bai, Donglin Guo, Changhong Guo & Yongjun Shu
Pages: 745-752
Published online: 08 Sep 2022
AbstractforTime-course RNA-seq analysis provides an improved understanding of genetic regulation in response to cold stress from white clover (Trifolium repens L.) | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 964 Views
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Article
Preoperative ultrasound assessment of myometrial invasion in endometrial cancer and prediction of surgical stage
Nikolay Geshev, Roumen Dimitrov, Vidin Kirkov, Alexandrina Vodenicharova, Antoniya Yanakieva & Sergei Slavov
Pages: 753-758
Published online: 08 Sep 2022
AbstractforPreoperative ultrasound assessment of myometrial invasion in endometrial cancer and prediction of surgical stage | Full Text | References | PDF (407.9 KB) | EPUB
  • 1417 Views
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Article
Genome-wide identification and expression analysis of the WRKY gene family in cabbage (Brassica oleracea var. capitata L.)
Xuyan Yang, Shuang Zhao, Wendong Ge, Tenghui Wang, Zhenyu Fan & Yushu Wang
Pages: 759-772
Published online: 08 Sep 2022
AbstractforGenome-wide identification and expression analysis of the WRKY gene family in cabbage (Brassica oleracea var. capitata L.) | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 979 Views
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Article
STING-associated vasculopathy with onset in infancy: the first case in Bulgaria and review of the literature
Margarita Ganeva, Guergana Petrova, Snezhina Mihailova, Nevena Gesheva, Mariya Nedevska, Martin Boyadzhiev, Petar Shivachev & Stefan Stefanov
Pages: 773-781
Published online: 12 Sep 2022
AbstractforSTING-associated vasculopathy with onset in infancy: the first case in Bulgaria and review of the literature | Full Text | References | PDF (917.6 KB) | EPUB
  • 994 Views
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Article
Characterization of the individual capacity for repair of genotoxic damage of a Bulgarian hESC line and two commonly used stabilized cell lines
Rumena Petkova, Pavlina Chelenkova, Borislav Arabadjiev, Roumen Pankov & Stoyan Chakarov
Pages: 782-787
Published online: 08 Sep 2022
AbstractforCharacterization of the individual capacity for repair of genotoxic damage of a Bulgarian hESC line and two commonly used stabilized cell lines | Full Text | References | PDF (424 KB) | EPUB
  • 397 Views
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Article
Analysis of cytokinin content and associated genes at different developmental stages in pak choi (Brassica rapa ssp. chinensis Makino)
Yue Bao, Xuan Li, Xianhui Qi, Xueting Wang, Xianjun Feng, Yinglong Chen, Leiping Hou & Meilan Li
Pages: 788-797
Published online: 08 Sep 2022
AbstractforAnalysis of cytokinin content and associated genes at different developmental stages in pak choi (Brassica rapa ssp. chinensis Makino) | Full Text | References | PDF (1.2 MB) | EPUB
  • 727 Views
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Correction

Correction
Correction
Pages: 798-801
Published online: 14 Oct 2022
First Page PreviewforCorrection | Full Text | PDF (252.6 KB) | EPUB
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Articles

Article
Nelumbo nucifera Gaertn. leaves: network pharmacology and molecular docking analysis of active ingredients and their mechanisms of action in treating atherosclerosis
Linhai Wang, Zhuoji Guan, Shaodong Li, Xin Dong, Jialin Jiang, Lingjun Wang & Shaoxiang Xian
Pages: 802-817
Published online: 13 Oct 2022
AbstractforNelumbo nucifera Gaertn. leaves: network pharmacology and molecular docking analysis of active ingredients and their mechanisms of action in treating atherosclerosis | Full Text | References | PDF (3.4 MB) | EPUB
  • 873 Views
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Article
Effect of exogenous melatonin on salt stress in cucumber: alleviating effect and molecular basis
Tingting Liu, Guoming Xing, Zhifeng Chen, Xijiao Zhai, Xuyang Wei, Chen Wang, Tianmeng Li & Shaowen Zheng
Pages: 818-827
Published online: 13 Oct 2022
AbstractforEffect of exogenous melatonin on salt stress in cucumber: alleviating effect and molecular basis | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1073 Views
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Article
Cost of arthropathic diseases therapy with biologicals disease modifying drugs (bDMARs): a 5-year cost analysis at national level
Konstantin Tachkov, Vladimira Boyadzhieva, Ivan Manev, Nikolay Stoilov, Zornitsa Mitkova, Konstantin Mitov & Guenka Petrova
Pages: 828-837
Published online: 19 Oct 2022
AbstractforCost of arthropathic diseases therapy with biologicals disease modifying drugs (bDMARs): a 5-year cost analysis at national level | Full Text | References | PDF (741 KB) | EPUB
  • 518 Views
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Article
An immobilization-based, loop-mediated isothermal amplification device for nucleic acid detection of SARS-CoV-2 N gene
Tianyu Song, Chang Chen, Shaoheng Bao, Bin Du, Xiaokun Wang, Jiajia Liu, Fuli Wang, Wei Ma, Ge Yao, Xiukun Wan, Xinlong Zhang, Jingjing Wang & Hui Jiang
Pages: 838-847
Published online: 31 Dec 2022
AbstractforAn immobilization-based, loop-mediated isothermal amplification device for nucleic acid detection of SARS-CoV-2 N gene | Full Text | References | PDF (977.8 KB) | EPUB | Supplemental
  • 667 Views
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Article
Cloning, expression and functional analysis of the SOC1 homologous gene in pak choi (Brassica rapa ssp. Chinensis makino)
Xuan Li, Amin Ping, Xianhui Qi, Meilan Li & Leiping Hou
Pages: 848-857
Published online: 19 Oct 2022
AbstractforCloning, expression and functional analysis of the SOC1 homologous gene in pak choi (Brassica rapa ssp. Chinensis makino) | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Reasons for requesting cone-beam computed tomography in children and adolescents: a 10-year study
Ebru Akleyin & Büşra Karaağaç Eskibağlar
Pages: 858-864
Published online: 26 Oct 2022
AbstractforReasons for requesting cone-beam computed tomography in children and adolescents: a 10-year study | Full Text | References | PDF (653.8 KB) | EPUB
  • 1189 Views
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Article
A novel prediction method for protein DNA-binding residues based on neighboring residue correlations
Jiazhi Song, Guixia Liu & Jingqing Jiang
Pages: 865-877
Published online: 27 Oct 2022
AbstractforA novel prediction method for protein DNA-binding residues based on neighboring residue correlations | Full Text | References | PDF (1.7 MB) | EPUB
  • 607 Views
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Article
Molasses fermentation to produce low-cost carbon source for denitrification
Chang Liu & Kai Cheng
Pages: 878-890
Published online: 29 Oct 2022
AbstractforMolasses fermentation to produce low-cost carbon source for denitrification | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 1641 Views
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Article
Ecophysiological characterization of a nitrite-oxidizing bacterial culture from a freshwater aquaculture pond
Runfeng Zhou, Yayuan Li, Shuwen Xiao, Xingguo Liu, Chong Liu, Guofeng Cheng, Wang Zhang & Shimin Lu
Pages: 891-901
Published online: 13 Nov 2022
AbstractforEcophysiological characterization of a nitrite-oxidizing bacterial culture from a freshwater aquaculture pond | Full Text | References | PDF (1.4 MB) | EPUB
  • 694 Views
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Article
AcdS gene of Bacillus cereus enhances salt tolerance of seedlings in tobacco (Nicotiana tabacum L.)
Zengyuan Tian, Yange Chen, Shuai Chen, Daoliang Yan, Xiaoming Wang & Yuqi Guo
Pages: 902-913
Published online: 14 Nov 2022
AbstractforAcdS gene of Bacillus cereus enhances salt tolerance of seedlings in tobacco (Nicotiana tabacum L.) | Full Text | References | PDF (1.3 MB) | EPUB
  • 691 Views
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Article
Light filtration technology for sustainable microalgal biomass production
Emmanuel Tapiwa Sero, Nqobizitha Siziba, Tavengwa Bunhu & Ryman Shoko
Pages: 914-924
Published online: 10 Nov 2022
AbstractforLight filtration technology for sustainable microalgal biomass production | Full Text | References | PDF (1 MB) | EPUB
  • 744 Views
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Article
In vitro and in silico inhibition performance of choline against CYP1A2, CYP2D6 and CYP3A4
Emilio Mateev, Antoaneta Balkanska-Mitkova, Lily Peikova, Maria Dimitrova & Magdalena Kondeva-Burdina
Pages: 925-932
Published online: 14 Nov 2022
AbstractforIn vitro and in silico inhibition performance of choline against CYP1A2, CYP2D6 and CYP3A4 | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 664 Views
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Article
A survey of knowledge, attitudes and use of antibiotics among Bulgarian population
Krassimira Zaykova, Silviya Nikolova, Rouzha Pancheva & Asena Serbezova
Pages: 933-941
Published online: 12 Nov 2022
AbstractforA survey of knowledge, attitudes and use of antibiotics among Bulgarian population | Full Text | References | PDF (605.4 KB) | EPUB
  • 2013 Views
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Article
High rate of fluoroquinolone resistant Neisseria gonorrhoeae detected by molecular surveillance of antimicrobial resistance determinants in Bulgaria
Ivva Philipova, Victoriya Levterova, Ivan Simeonovski & Todor Kantardjiev
Pages: 942-948
Published online: 17 Nov 2022
AbstractforHigh rate of fluoroquinolone resistant Neisseria gonorrhoeae detected by molecular surveillance of antimicrobial resistance determinants in Bulgaria | Full Text | References | PDF (704.3 KB) | EPUB
  • 547 Views
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Article
Inhibitory activity of carbon quantum dots against Phytophthora infestans and fungal plant pathogens and their effect on dsRNA-induced gene silencing
Kaloyan Kostov, Boika Andonova-Lilova & Guy Smagghe
Pages: 949-959
Published online: 21 Nov 2022
AbstractforInhibitory activity of carbon quantum dots against Phytophthora infestans and fungal plant pathogens and their effect on dsRNA-induced gene silencing | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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