Journal of Extracellular Vesicles, Volume 9, Issue 1 (2020)

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Journal of Extracellular Vesicles, Volume 9, Issue 1 (2020)

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Purity and yield of melanoma exosomes are dependent on isolation method
Shin La Shu, Yunchen Yang, Cheryl L. Allen, Edward Hurley, Kaity H. Tung, Hans Minderman, Yun Wu & Marc S. Ernstoff
Article: 1692401
Published online: 20 Nov 2019
AbstractforPurity and yield of melanoma exosomes are dependent on isolation method | Full Text | References | PDF (2.2 MB) | Supplemental
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Research Articles

Article
Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle–mediated release of ezrin to inhibit tumour cell movement
Chao Huang, Franklin A. Hays, James J. Tomasek, Siribhinya Benyajati & Xin A. Zhang
Article: 1692417
Published online: 25 Nov 2019
AbstractforTetraspanin CD82 interaction with cholesterol promotes extracellular vesicle–mediated release of ezrin to inhibit tumour cell movement | Full Text | References | PDF (3.3 MB) | Supplemental
  • 2652 Views
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Research Article

Article
Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance
Akihiro Matsumoto, Yuki Takahashi, Hsin-Yi Chang, Yi-Wen Wu, Aki Yamamoto, Yasushi Ishihama & Yoshinobu Takakura
Article: 1696517
Published online: 26 Nov 2019
AbstractforBlood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance | Full Text | References | PDF (2.8 MB) | Supplemental
  • 4669 Views
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Article
Large and small extracellular vesicles released by glioma cells in vitro and in vivo
Anudeep Yekula, Valentina R. Minciacchi, Matteo Morello, Huilin Shao, Yongil Park, Xuan Zhang, Koushik Muralidharan, Michael R. Freeman, Ralph Weissleder, Hakho Lee, Bob Carter, Xandra O. Breakefield, Dolores Di Vizio & Leonora Balaj
Article: 1689784
Published online: 27 Nov 2019
AbstractforLarge and small extracellular vesicles released by glioma cells in vitro and in vivo | Full Text | References | PDF (1.5 MB) | Supplemental
  • 4381 Views
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Article
Quality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry
Ye Tian, Manfei Gong, Yunyun Hu, Haisheng Liu, Wenqiang Zhang, Miaomiao Zhang, Xiuxiu Hu, Dimitri Aubert, Shaobin Zhu, Lina Wu & Xiaomei Yan
Article: 1697028
Published online: 29 Nov 2019
AbstractforQuality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry | Full Text | References | PDF (2.9 MB) | Supplemental
  • 14018 Views
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Article
MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression
Xing-Sheng Ren, Ying Tong, Yun Qiu, Chao Ye, Nan Wu, Xiao-Qing Xiong, Jue-Jin Wang, Ying Han, Ye-Bo Zhou, Feng Zhang, Hai-Jian Sun, Xing-Ya Gao, Qi Chen, Yue-Hua Li, Yu-Ming Kang & Guo-Qing Zhu
Article: 1698795
Published online: 02 Dec 2019
AbstractforMiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression | Full Text | References | PDF (4.5 MB) | Supplemental
  • 3893 Views
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Article
Role of Mac-1 integrin in generation of extracellular vesicles with antibacterial capacity from neutrophilic granulocytes
Ákos M. Lőrincz, Balázs Bartos, Dávid Szombath, Viktória Szeifert, Csaba I. Timár, Lilla Turiák, László Drahos, Ágnes Kittel, Dániel S. Veres, Ferenc Kolonics, Attila Mócsai & Erzsébet Ligeti
Article: 1698889
Published online: 09 Dec 2019
AbstractforRole of Mac-1 integrin in generation of extracellular vesicles with antibacterial capacity from neutrophilic granulocytes | Full Text | References | PDF (2.5 MB) | Supplemental
  • 2049 Views
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Article
Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells
Yuting Liang, Sheng Huang, Longwei Qiao, Xia Peng, Chong Li, Kun Lin, Guogang Xie, Jia Li, Lihui Lin, Yue Yin, Huanjin Liao, Qian Li & Li Li
Article: 1697583
Published online: 06 Dec 2019
AbstractforCharacterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells | Full Text | References | PDF (6.1 MB) | Supplemental
  • 2903 Views
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Editorial

Editorial
The EV-TRACK summary add-on: integration of experimental information in databases to ensure comprehensive interpretation of biological knowledge on extracellular vesicles
Quentin Roux, Jan Van Deun, Sandor Dedeyne & An Hendrix
Article: 1699367
Published online: 05 Jan 2020
First Page PreviewforThe EV-TRACK summary add-on: integration of experimental information in databases to ensure comprehensive interpretation of biological knowledge on extracellular vesicles | Full Text | References | PDF (1 MB)
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Article

Article
Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets
Samuel Antwi-Baffour, Memory Malibha-Pinchbeck, Dan Stratton, Samireh Jorfi, Sigrun Lange & Jameel Inal
Article: 1697124
Published online: 18 Dec 2019
AbstractforPlasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets | Full Text | References | PDF (2.1 MB) | Supplemental
  • 1439 Views
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Research Article

Article
Anti-melanogenic effects of extracellular vesicles derived from plant leaves and stems in mouse melanoma cells and human healthy skin
Ruri Lee, Hae Ju Ko, Kimin Kim, Yehjoo Sohn, Seo Yun Min, Jeong Ah Kim, Dokyun Na & Ju Hun Yeon
Article: 1703480
Published online: 18 Dec 2019
AbstractforAnti-melanogenic effects of extracellular vesicles derived from plant leaves and stems in mouse melanoma cells and human healthy skin | Full Text | References | PDF (2 MB) | Supplemental
  • 5374 Views
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Article

Article
Neuronal-derived extracellular vesicles are enriched in the brain and serum of HIV-1 transgenic rats
Raghubendra Singh Dagur, Ke Liao, Susmita Sil, Fang Niu, Zhiqiang Sun, Yuri L. Lyubchenko, Eric S. Peeples, Guoku Hu & Shilpa Buch
Article: 1703249
Published online: 20 Dec 2019
AbstractforNeuronal-derived extracellular vesicles are enriched in the brain and serum of HIV-1 transgenic rats | Full Text | References | PDF (1.9 MB)
  • 2665 Views
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Review Article

Review Article
Inhibiting extracellular vesicles formation and release: a review of EV inhibitors
Mariadelva Catalano & Lorraine O’Driscoll
Article: 1703244
Published online: 19 Dec 2019
AbstractforInhibiting extracellular vesicles formation and release: a review of EV inhibitors | Full Text | References | PDF (2.1 MB)
  • 14894 Views
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Research Articles

Article
Monocytes mediate homing of circulating microvesicles to the pulmonary vasculature during low-grade systemic inflammation
Kieran P. O’Dea, Ying Ying Tan, Sneh Shah, Brijesh V Patel, Kate C Tatham, Mike R. Wilson, Sanooj Soni & Masao Takata
Article: 1706708
Published online: 05 Jan 2020
AbstractforMonocytes mediate homing of circulating microvesicles to the pulmonary vasculature during low-grade systemic inflammation | Full Text | References | PDF (3.2 MB) | Supplemental
  • 3203 Views
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Research Article

Article
Activated human astrocyte-derived extracellular vesicles modulate neuronal uptake, differentiation and firing
Yang You, Kathleen Borgmann, Venkata Viswanadh Edara, Satomi Stacy, Anuja Ghorpade & Tsuneya Ikezu
Article: 1706801
Published online: 26 Dec 2019
AbstractforActivated human astrocyte-derived extracellular vesicles modulate neuronal uptake, differentiation and firing | Full Text | References | PDF (3.2 MB) | Supplemental
  • 6107 Views
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Article
Exosomal PD-L1 functions as an immunosuppressant to promote wound healing
Dandan Su, Hsiang-I Tsai, Zhanxue Xu, Fuxia Yan, Yingyi Wu, Youmei Xiao, Xiaoyan Liu, Yanping Wu, Sepideh Parvanian, Wangshu Zhu, John E. Eriksson, Dongqing Wang, Haitao Zhu, Hongbo Chen & Fang Cheng
Article: 1709262
Published online: 27 Dec 2019
AbstractforExosomal PD-L1 functions as an immunosuppressant to promote wound healing | Full Text | References | PDF (1.9 MB)
  • 4993 Views
  • 55 CrossRef citations
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Article
Tracking the evolution of circulating exosomal-PD-L1 to monitor melanoma patients
Marine Cordonnier, Charlée Nardin, Gaëtan Chanteloup, Valentin Derangere, Marie-Paule Algros, Laurent Arnould, Carmen Garrido, François Aubin & Jessica Gobbo
Article: 1710899
Published online: 07 Jan 2020
AbstractforTracking the evolution of circulating exosomal-PD-L1 to monitor melanoma patients | Full Text | References | PDF (1.6 MB) | Supplemental
  • 5654 Views
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Review Article

Review Article
Phenotypic analysis of extracellular vesicles: a review on the applications of fluorescence
Maria S. Panagopoulou, Alastair W. Wark, David J S Birch & Christopher D. Gregory
Article: 1710020
Published online: 07 Jan 2020
AbstractforPhenotypic analysis of extracellular vesicles: a review on the applications of fluorescence | Full Text | References | PDF (1.7 MB)
  • 8993 Views
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Article

Article
Altered biodistribution of deglycosylated extracellular vesicles through enhanced cellular uptake
Nao Nishida-Aoki, Naoomi Tominaga, Nobuyoshi Kosaka & Takahiro Ochiya
Article: 1713527
Published online: 13 Jan 2020
AbstractforAltered biodistribution of deglycosylated extracellular vesicles through enhanced cellular uptake | Full Text | References | PDF (1.5 MB) | Supplemental
  • 3114 Views
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Research Articles

Article
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
Wang Jiang, Pengjuan Ma, Libin Deng, Zhi Liu, Xu Wang, Xiyu Liu & Gang Long
Article: 1716513
Published online: 22 Jan 2020
AbstractforHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles | Full Text | References | PDF (2.9 MB) | Supplemental
  • 3369 Views
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Research Article

Article
Extracellular microRNAs in blood differentiate between ischaemic and haemorrhagic stroke subtypes
M. Yashar S. Kalani, Eric Alsop, Bessie Meechoovet, Taylor Beecroft, Komal Agrawal, Timothy G. Whitsett, Matthew J. Huentelman, Robert F. Spetzler, Peter Nakaji, Seungchan Kim & Kendall Van Keuren-Jensen
Article: 1713540
Published online: 24 Jan 2020
AbstractforExtracellular microRNAs in blood differentiate between ischaemic and haemorrhagic stroke subtypes | Full Text | References | PDF (2.3 MB) | Supplemental
  • 2359 Views
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Article

Article
MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments
Joshua A. Welsh, Edwin Van Der Pol, Ger J.A. Arkesteijn, Michel Bremer, Alain Brisson, Frank Coumans, Françoise Dignat-George, Erika Duggan, Ionita Ghiran, Bernd Giebel, André Görgens, An Hendrix, Romaric Lacroix, Joanne Lannigan, Sten F.W.M. Libregts, Estefanía Lozano-Andrés, Aizea Morales-Kastresana, Stephane Robert, Leonie De Rond, Tobias Tertel, John Tigges, Olivier De Wever, Xiaomei Yan, Rienk Nieuwland, Marca H.M. Wauben, John P. Nolan & Jennifer C. Jones
Article: 1713526
Published online: 03 Feb 2020
AbstractforMIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments | Full Text | References | PDF (3.1 MB) | Supplemental
  • 15516 Views
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Research Articles

Article
Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation
Rossella Crescitelli, Cecilia Lässer, Su Chul Jang, Aleksander Cvjetkovic, Carina Malmhäll, Nasibeh Karimi, Johanna L. Höög, Iva Johansson, Johannes Fuchs, Annika Thorsell, Yong Song Gho, R. Olofsson Bagge & Jan Lötvall
Article: 1722433
Published online: 11 Feb 2020
AbstractforSubpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation | Full Text | References | PDF (4.7 MB) | Supplemental
  • 6068 Views
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Research Article

Article
Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells
Yinuo Lin, Chi Zhang, Pingping Xiang, Jian Shen, Weijian Sun & Hong Yu
Article: 1722385
Published online: 03 Feb 2020
AbstractforExosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells | Full Text | References | PDF (3.1 MB) | Supplemental
  • 3986 Views
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Article
Small extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell-dominant allergic airway inflammation through delivery of miR-146a-5p
Shu-Bin Fang, Hong-Yu Zhang, Cong Wang, Bi-Xin He, Xiao-Qing Liu, Xiang-Ci Meng, Ya-Qi Peng, Zhi-Bin Xu, Xing-Liang Fan, Zhang-Jin Wu, Dong Chen, Lei Zheng, Song Guo Zheng & Qing-Ling Fu
Article: 1723260
Published online: 10 Feb 2020
AbstractforSmall extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell-dominant allergic airway inflammation through delivery of miR-146a-5p | Full Text | References | PDF (3.8 MB) | Supplemental
  • 4258 Views
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Article
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
Emanuela Mensà, Michele Guescini, Angelica Giuliani, Maria Giulia Bacalini, Deborah Ramini, Giacomo Corleone, Manuela Ferracin, Gianluca Fulgenzi, Laura Graciotti, Francesco Prattichizzo, Leonardo Sorci, Michela Battistelli, Vladia Monsurrò, Anna Rita Bonfigli, Maurizio Cardelli, Rina Recchioni, Fiorella Marcheselli, Silvia Latini, Serena Maggio, Mirco Fanelli, Stefano Amatori, Gianluca Storci, Antonio Ceriello, Vilberto Stocchi, Maria De Luca, Luca Magnani, Maria Rita Rippo, Antonio Domenico Procopio, Claudia Sala, Iva Budimir, Cristian Bassi, Massimo Negrini, Paolo Garagnani, Claudio Franceschi, Jacopo Sabbatinelli, Massimiliano Bonafè & Fabiola Olivieri
Article: 1725285
Published online: 18 Feb 2020
AbstractforSmall extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells | Full Text | References | PDF (7.2 MB) | Supplemental
  • 4660 Views
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Article
Location of neonatal microglia drives small extracellular vesicles content and biological functions in vitro
Adriana-Natalia Murgoci, Marie Duhamel, Antonella Raffo-Romero, Khalil Mallah, Soulaimane Aboulouard, Christophe Lefebvre, Firas Kobeissy, Isabelle Fournier, Monika Zilkova, Denisa Maderova, Milan Cizek, Dasa Cizkova & Michel Salzet
Article: 1727637
Published online: 18 Feb 2020
AbstractforLocation of neonatal microglia drives small extracellular vesicles content and biological functions in vitro | Full Text | References | PDF (4.6 MB) | Supplemental
  • 1998 Views
  • 18 CrossRef citations
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Article
Functional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD)
Goren Saenz-Pipaon, Patxi San Martín, Núria Planell, Alberto Maillo, Susana Ravassa, Amaia Vilas-Zornoza, Esther Martinez-Aguilar, José Antonio Rodriguez, Daniel Alameda, David Lara-Astiaso, Felipe Prosper, José Antonio Paramo, Josune Orbe, David Gomez-Cabrero & Carmen Roncal
Article: 1729646
Published online: 19 Feb 2020
AbstractforFunctional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD) | Full Text | References | PDF (2.7 MB) | Supplemental
  • 2227 Views
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Article
Label-free identification and chemical characterisation of single extracellular vesicles and lipoproteins by synchronous Rayleigh and Raman scattering
Agustin Enciso-Martinez, Edwin Van Der Pol, Chi M. Hau, Rienk Nieuwland, Ton G. Van Leeuwen, Leon W.M.M. Terstappen & Cees Otto
Article: 1730134
Published online: 19 Feb 2020
AbstractforLabel-free identification and chemical characterisation of single extracellular vesicles and lipoproteins by synchronous Rayleigh and Raman scattering | Full Text | References | PDF (2.5 MB) | Supplemental
  • 2614 Views
  • 31 CrossRef citations
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Article
Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy
Jack Taylor, Iman Azimi, Gregory Monteith & Mary Bebawy
Article: 1734326
Published online: 03 Mar 2020
AbstractforCa2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy | Full Text | References | PDF (2.1 MB)
  • 2338 Views
  • 46 CrossRef citations
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Article
Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration
Chang Hee Woo, Hark Kyun Kim, Gun Young Jung, Youn Jae Jung, Kyoung Soo Lee, Ye Eun Yun, Jihoon Han, Jeongmi Lee, Woo Sung Kim, Ji Suk Choi, Siyoung Yang, Jae Hyung Park, Dong-Gyu Jo & Yong Woo Cho
Article: 1735249
Published online: 09 Mar 2020
AbstractforSmall extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration | Full Text | References | PDF (3 MB) | Supplemental
  • 5735 Views
  • 139 CrossRef citations
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Article
Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Bert Dhondt, Edward Geeurickx, Joeri Tulkens, Jan Van Deun, Glenn Vergauwen, Lien Lippens, Ilkka Miinalainen, Pekka Rappu, Jyrki Heino, Piet Ost, Nicolaas Lumen, Olivier De Wever & An Hendrix
Article: 1736935
Published online: 11 Mar 2020
AbstractforUnravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine | Full Text | References | PDF (4.2 MB) | Supplemental
  • 8301 Views
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Article

Article
Extracellular vesicles from plasma have higher tumour RNA fraction than platelets
Kay Brinkman, Lisa Meyer, Anne Bickel, Daniel Enderle, Carola Berking, Johan Skog & Mikkel Noerholm
Article: 1741176
Published online: 25 Mar 2020
AbstractforExtracellular vesicles from plasma have higher tumour RNA fraction than platelets | Full Text | References | PDF (1 MB) | Supplemental
  • 2009 Views
  • 20 CrossRef citations
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Research Articles

Article
Fourier-transform Infrared (FT-IR) spectroscopy fingerprints subpopulations of extracellular vesicles of different sizes and cellular origin
Lucia Paolini, Stefania Federici, Giovanni Consoli, Diletta Arceri, Annalisa Radeghieri, Ivano Alessandri & Paolo Bergese
Article: 1741174
Published online: 30 Mar 2020
AbstractforFourier-transform Infrared (FT-IR) spectroscopy fingerprints subpopulations of extracellular vesicles of different sizes and cellular origin | Full Text | References | PDF (2.1 MB) | Supplemental
  • 2731 Views
  • 36 CrossRef citations
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Research Article

Article
Heterogeneity of the nucleic acid repertoire of plasma extracellular vesicles demonstrated using high-sensitivity fluorescence-activated sorting
Kirill Kondratov, Yuri Nikitin, Anton Fedorov, Anna Kostareva, Vladimir Mikhailovskii, Dmitry Isakov, Andrey Ivanov & Alexey Golovkin
Article: 1743139
Published online: 30 Mar 2020
AbstractforHeterogeneity of the nucleic acid repertoire of plasma extracellular vesicles demonstrated using high-sensitivity fluorescence-activated sorting | Full Text | References | PDF (3.2 MB) | Supplemental
  • 1890 Views
  • 19 CrossRef citations
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Article
DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination
Chu-An Wang, I-Heng Chang, Pei-Chi Hou, Yu-Jing Tai, Wan-Ning Li, Pei-Ling Hsu, Shang-Rung Wu, Wen-Tai Chiu, Chien-Feng Li, Yan-Shen Shan & Shaw-Jenq Tsai
Article: 1746529
Published online: 04 Apr 2020
AbstractforDUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination | Full Text | References | PDF (2.9 MB) | Supplemental
  • 1951 Views
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Article
A circulating extracellular vesicles-based novel screening tool for colorectal cancer revealed by shotgun and data-independent acquisition mass spectrometry
Xi Zheng, Kailun Xu, Biting Zhou, Ting Chen, Yanqin Huang, Qilong Li, Fei Wen, Weiting Ge, Jian Wang, Shaojun Yu, Lifeng Sun, Liang Zhu, Wei Liu, Huanhuan Gao, Liang Yue, Xue Cai, Qiushi Zhang, Guan Ruan, Tiansheng Zhu, Zhicheng Wu, Yi Zhu, Yingkuan Shao, Tiannan Guo & Shu Zheng
Article: 1750202
Published online: 14 Apr 2020
AbstractforA circulating extracellular vesicles-based novel screening tool for colorectal cancer revealed by shotgun and data-independent acquisition mass spectrometry | Full Text | References | PDF (3.6 MB) | Supplemental
  • 3437 Views
  • 54 CrossRef citations
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Article
Membrane-binding peptides for extracellular vesicles on-chip analysis
Alessandro Gori, Alessandro Romanato, Greta Bergamaschi, Alessandro Strada, Paola Gagni, Roberto Frigerio, Dario Brambilla, Riccardo Vago, Silvia Galbiati, Silvia Picciolini, Marzia Bedoni, George G. Daaboul, Marcella Chiari & Marina Cretich
Article: 1751428
Published online: 17 Apr 2020
AbstractforMembrane-binding peptides for extracellular vesicles on-chip analysis | Full Text | References | PDF (3.1 MB) | Supplemental
  • 4876 Views
  • 36 CrossRef citations
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Article
Protein markers for Candida albicans EVs include claudin-like Sur7 family proteins
Charlotte S Dawson, Donovan Garcia-Ceron, Harinda Rajapaksha, Pierre Faou, Mark R Bleackley & Marilyn A Anderson
Article: 1750810
Published online: 16 Apr 2020
AbstractforProtein markers for Candida albicans EVs include claudin-like Sur7 family proteins | Full Text | References | PDF (3.6 MB) | Supplemental
  • 2323 Views
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Article
Extracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery
Heikki Saari, Tiia Turunen, Andres Lõhmus, Mikko Turunen, Matti Jalasvuori, Sarah J. Butcher, Seppo Ylä-Herttuala, Tapani Viitala, Vincenzo Cerullo, Pia R. M. Siljander & Marjo Yliperttula
Article: 1747206
Published online: 17 Apr 2020
AbstractforExtracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery | Full Text | References | PDF (4.7 MB) | Supplemental
  • 2489 Views
  • 21 CrossRef citations
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Article
Exosomes derived from neural progenitor cells preserve photoreceptors during retinal degeneration by inactivating microglia
Baishijiao Bian, Congjian Zhao, Xiangyu He, Yu Gong, Chunge Ren, Lingling Ge, Yuxiao Zeng, Qiyou Li, Min Chen, Chuanhuang Weng, Juncai He, Yajie Fang, Haiwei Xu & Zheng Qin Yin
Article: 1748931
Published online: 21 Apr 2020
AbstractforExosomes derived from neural progenitor cells preserve photoreceptors during retinal degeneration by inactivating microglia | Full Text | References | PDF (4.2 MB) | Supplemental
  • 3242 Views
  • 66 CrossRef citations
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Article
DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells
Marije E. Kuipers, Esther N.M. Nolte-‘t Hoen, Alwin J. van der Ham, Arifa Ozir-Fazalalikhan, D. Linh Nguyen, Clarize M. de Korne, Roman I. Koning, John J. Tomes, Karl F. Hoffmann, Hermelijn H. Smits & Cornelis H. Hokke
Article: 1753420
Published online: 30 Apr 2020
AbstractforDC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells | Full Text | References | PDF (3.6 MB)
  • 2688 Views
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Article
Quantitative proteomic analysis of trypsin-treated extracellular vesicles to identify the real-vesicular proteins
Dongsic Choi, Gyeongyun Go, Dae-Kyum Kim, Jaewook Lee, Seon-Min Park, Dolores Di Vizio & Yong Song Gho
Article: 1757209
Published online: 30 Apr 2020
AbstractforQuantitative proteomic analysis of trypsin-treated extracellular vesicles to identify the real-vesicular proteins | Full Text | References | PDF (2.3 MB) | Supplemental
  • 3654 Views
  • 21 CrossRef citations
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Article
CD73+ extracellular vesicles inhibit angiogenesis through adenosine A2B receptor signalling
Roberta Angioni, Cristina Liboni, Stephanie Herkenne, Ricardo Sánchez-Rodríguez, Giulia Borile, Elisabetta Marcuzzi, Bianca Calì, Maurizio Muraca & Antonella Viola
Article: 1757900
Published online: 04 May 2020
AbstractforCD73+ extracellular vesicles inhibit angiogenesis through adenosine A2B receptor signalling | Full Text | References | PDF (3.1 MB) | Supplemental
  • 2186 Views
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Article
Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells
Fabio Quaglia, Shiv Ram Krishn, George G. Daaboul, Srawasti Sarker, Raffaella Pippa, Josep Domingo-Domenech, Gaurav Kumar, Paolo Fortina, Peter McCue, William K. Kelly, Himisha Beltran, Qin Liu & Lucia R. Languino
Article: 1761072
Published online: 24 May 2020
AbstractforSmall extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells | Full Text | References | PDF (2.6 MB) | Supplemental
  • 1895 Views
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Article
Actin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes
Ana Bello-Gamboa, Marta Velasco, Solange Moreno, Gonzalo Herranz, Roxana Ilie, Silvia Huetos, Sergio Dávila, Alicia Sánchez, Jorge Bernardino De La Serna, Víctor Calvo & Manuel Izquierdo
Article: 1759926
Published online: 19 Jun 2020
AbstractforActin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes | Full Text | References | PDF (3.1 MB) | Supplemental
  • 4376 Views
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Article
The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis
Shiv Ram Krishn, Israa Salem, Fabio Quaglia, Nicole M. Naranjo, Ekta Agarwal, Qin Liu, Srawasti Sarker, Jessica Kopenhaver, Peter A. McCue, Paul H. Weinreb, Shelia M. Violette, Dario C. Altieri & Lucia R. Languino
Article: 1763594
Published online: 20 May 2020
AbstractforThe αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis | Full Text | References | PDF (3.1 MB) | Supplemental
  • 2476 Views
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Article
Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles
Javier Mariscal, Tatyana Vagner, Minhyung Kim, Bo Zhou, Andrew Chin, Mandana Zandian, Michael R. Freeman, Sungyong You, Andries Zijlstra, Wei Yang & Dolores Di Vizio
Article: 1764192
Published online: 10 Jun 2020
AbstractforComprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles | Full Text | References | PDF (3.1 MB) | Supplemental
  • 2831 Views
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Article
Indoor dust extracellular vesicles promote cancer lung metastasis by inducing tumour necrosis factor-α
Nhung Thi Hong Dinh, Jaewook Lee, Jaemin Lee, Sang Soo Kim, Gyeongyun Go, Seoyoon Bae, Ye In Jun, Yae Jin Yoon, Tae-Young Roh & Yong Song Gho
Article: 1766821
Published online: 19 May 2020
AbstractforIndoor dust extracellular vesicles promote cancer lung metastasis by inducing tumour necrosis factor-α | Full Text | References | PDF (1.9 MB) | Supplemental
  • 2112 Views
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Short Communication

Monitoring HSP70 exosomes in cancer patients’ follow up: a clinical prospective pilot study
Gaëtan Chanteloup, Marine Cordonnier, Nicolas Isambert, Aurélie Bertaut, Alice Hervieu, Audrey Hennequin, Maxime Luu, Sylvie Zanetta, Bruno Coudert, Leila Bengrine, Isabelle Desmoulins, Laure Favier, Aurélie Lagrange, Pierre-Benoit Pages, Ivan Gutierrez, Jeanine Lherminier, Laure Avoscan, Clémentine Jankowski, Cédric Rébé, Angélique Chevriaux, Marie-Martine Padeano, Charles Coutant, Sylvain Ladoire, Sylvain Causeret, Laurent Arnould, Céline Charon-Barra, Vanessa Cottet, Julie Blanc, Christine Binquet, Marc Bardou, Carmen Garrido & Jessica Gobbo
Article: 1766192
Published online: 20 May 2020
AbstractforMonitoring HSP70 exosomes in cancer patients’ follow up: a clinical prospective pilot study | Full Text | References | PDF (1.2 MB) | Supplemental
  • 2927 Views
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Research article

Article
Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer
Kisho Ono, Chiharu Sogawa, Hotaka Kawai, Manh Tien Tran, Eman A. Taha, Yanyin Lu, May Wathone Oo, Yuka Okusha, Hirohiko Okamura, Soichiro Ibaragi, Masaharu Takigawa, Ken-Ichi Kozaki, Hitoshi Nagatsuka, Akira Sasaki, Kuniaki Okamoto, Stuart K. Calderwood & Takanori Eguchi
Article: 1769373
Published online: 31 May 2020
AbstractforTriple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer | Full Text | References | PDF (3.3 MB) | Supplemental
  • 2949 Views
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Research Article

Article
Y-RNA subtype ratios in plasma extracellular vesicles are cell type- specific and are candidate biomarkers for inflammatory diseases
Tom A.P. Driedonks, Sanne Mol, Sanne de Bruin, Anna-Linda Peters, Xiaogang Zhang, Marthe F.S. Lindenbergh, Boukje M. Beuger, Anne-Marieke D. van Stalborch, Thom Spaan, Esther C. de Jong, Erhard van der Vries, Coert Margadant, Robin van Bruggen, Alexander P.J. Vlaar, Tom Groot Kormelink & Esther N.M. Nolte-‘T Hoen
Article: 1764213
Published online: 26 May 2020
AbstractforY-RNA subtype ratios in plasma extracellular vesicles are cell type- specific and are candidate biomarkers for inflammatory diseases | Full Text | References | PDF (2.9 MB) | Supplemental
  • 2498 Views
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Article
Small RNA fingerprinting of Alzheimer’s disease frontal cortex extracellular vesicles and their comparison with peripheral extracellular vesicles
Lesley Cheng, Laura J. Vella, Kevin J. Barnham, Catriona McLean, Colin L. Masters & Andrew F. Hill
Article: 1766822
Published online: 04 Jun 2020
AbstractforSmall RNA fingerprinting of Alzheimer’s disease frontal cortex extracellular vesicles and their comparison with peripheral extracellular vesicles | Full Text | References | PDF (2.6 MB) | Supplemental
  • 3070 Views
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Research article

Article
Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells
Marta Colletti, Luigi Tomao, Angela Galardi, Alessandro Paolini, Virginia Di Paolo, Cristiano De Stefanis, Paolo Mascio, Francesca Nazio, Stefania Petrini, Aurora Castellano, Ida Russo, Roberta Caruso, Simone Piga, Rita De Vito, Luisa Pascucci, Hector Peinado, Andrea Masotti, Franco Locatelli & Angela Di Giannatale
Article: 1774144
Published online: 03 Jun 2020
AbstractforNeuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells | Full Text | References | PDF (5.8 MB) | Supplemental
  • 1953 Views
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Research Article

Article
miR-23a-3p-abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration
Hongxing Hu, Lanlan Dong, Ziheng Bu, Yifan Shen, Jian Luo, Hang Zhang, Shichang Zhao, Fang Lv & Zhongtang Liu
Article: 1778883
Published online: 16 Jun 2020
AbstractformiR-23a-3p-abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration | Full Text | References | PDF (5.6 MB) | Supplemental
  • 3528 Views
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Research article

Article
Endothelial cell-derived extracellular vesicles alter vascular smooth muscle cell phenotype through high-mobility group box proteins
Michael J. Boyer, Yayoi Kimura, Tomoko Akiyama, Ariele Y. Baggett, Kyle J. Preston, Rosario Scalia, Satoru Eguchi & Victor Rizzo
Article: 1781427
Published online: 18 Jun 2020
AbstractforEndothelial cell-derived extracellular vesicles alter vascular smooth muscle cell phenotype through high-mobility group box proteins | Full Text | References | PDF (2.5 MB) | Supplemental
  • 2665 Views
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Article
Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling
Lizhou Xu, Farid N. Faruqu, Revadee Liam-or, Omar Abu Abed, Danyang Li, Kerrie Venner, Rachel J Errington, Huw Summers, Julie Tzu-Wen Wang & Khuloud T. Al-Jamal
Article: 1779458
Published online: 19 Jun 2020
AbstractforDesign of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling | Full Text | References | PDF (6.5 MB) | Supplemental
  • 4153 Views
  • 44 CrossRef citations
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Article
Stem cell-derived extracellular vesicles mitigate ageing-associated arterial stiffness and hypertension
Rui Feng, Mujib Ullah, Kai Chen, Quaisar Ali, Yi Lin & Zhongjie Sun
Article: 1783869
Published online: 24 Jun 2020
AbstractforStem cell-derived extracellular vesicles mitigate ageing-associated arterial stiffness and hypertension | Full Text | References | PDF (4.7 MB) | Supplemental
  • 2512 Views
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Editorial

Editorial
Stumbling on elusive cargo: how isomiRs challenge microRNA detection and quantification, the case of extracellular vesicles
S. Eréndira Avendaño-Vázquez & C. Fabián Flores-Jasso
Article: 1784617
Published online: 28 Jun 2020
First Page PreviewforStumbling on elusive cargo: how isomiRs challenge microRNA detection and quantification, the case of extracellular vesicles | Full Text | References | PDF (977.5 KB)
  • 1807 Views
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Review article

Review Article
Exosome therapeutics for lung regenerative medicine
Kristen Popowski, Halle Lutz, Shiqi Hu, Arianna George, Phuong-Uyen Dinh & Ke Cheng
Article: 1785161
Published online: 29 Jun 2020
AbstractforExosome therapeutics for lung regenerative medicine | Full Text | References | PDF (1.6 MB)
  • 4458 Views
  • 50 CrossRef citations
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Research article

Article
Sja-miR-71a in Schistosome egg-derived extracellular vesicles suppresses liver fibrosis caused by schistosomiasis via targeting semaphorin 4D
Lifu Wang, Yao Liao, Ruibing Yang, Zilong Yu, Lichao Zhang, Zifeng Zhu, Xiaoying Wu, Jia Shen, Jiahua Liu, Lian Xu, Zhongdao Wu & Xi Sun
Article: 1785738
Published online: 09 Jul 2020
AbstractforSja-miR-71a in Schistosome egg-derived extracellular vesicles suppresses liver fibrosis caused by schistosomiasis via targeting semaphorin 4D | Full Text | References | PDF (23.5 MB) | Supplemental
  • 2000 Views
  • 27 CrossRef citations
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Research Article

Article
Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles
Yiyao Huang, Lesley Cheng, Andrey Turchinovich, Vasiliki Mahairaki, Juan C. Troncoso, Olga Pletniková, Norman J. Haughey, Laura J. Vella, Andrew F. Hill, Lei Zheng & Kenneth W. Witwer
Article: 1785746
Published online: 30 Jun 2020
AbstractforInfluence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles | Full Text | References | PDF (10.2 MB) | Supplemental
  • 3290 Views
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Research article

Article
The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles
Andreas Zietzer, Mohammed Rabiul Hosen, Han Wang, Philip Roger Goody, Marc Sylvester, Eicke Latz, Georg Nickenig, Nikos Werner & Felix Jansen
Article: 1786967
Published online: 02 Jul 2020
AbstractforThe RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles | Full Text | References | PDF (12 MB) | Supplemental
  • 3846 Views
  • 44 CrossRef citations
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Article
miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas
Joseph P. Flemming, Brianna L. Hill, Mohammed W. Haque, Jessica Raad, Claudine S. Bonder, Larry A. Harshyne, Ulrich Rodeck, Adam Luginbuhl, James K. Wahl III, Kenneth Y. Tsai, Peter J. Wermuth, Andrew M. Overmiller & Mỹ G. Mahoney
Article: 1790159
Published online: 13 Jul 2020
AbstractformiRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas | Full Text | References | PDF (13.4 MB)
  • 2635 Views
  • 26 CrossRef citations
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Article
Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury
Gareth R. Willis, Angeles Fernandez-Gonzalez, Monica Reis, Vincent Yeung, Xianlan Liu, Maria Ericsson, Nick A. Andrews, S. Alex Mitsialis & Stella Kourembanas
Article: 1790874
Published online: 13 Jul 2020
AbstractforMesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury | Full Text | References | PDF (8.7 MB) | Supplemental
  • 2139 Views
  • 49 CrossRef citations
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Article
A novel three step protocol to isolate extracellular vesicles from plasma or cell culture medium with both high yield and purity
Xiaogang Zhang, Ellen G. F. Borg, A. Manuel Liaci, Harmjan R. Vos & Willem Stoorvogel
Article: 1791450
Published online: 14 Jul 2020
AbstractforA novel three step protocol to isolate extracellular vesicles from plasma or cell culture medium with both high yield and purity | Full Text | References | PDF (6.6 MB) | Supplemental
  • 6743 Views
  • 69 CrossRef citations
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Article
Cargo and cell-specific differences in extracellular vesicle populations identified by multiplexed immunofluorescent analysis
Kevin Burbidge, Virginia Zwikelmaier, Ben Cook, Michael M. Long, Barak Balva, Michael Lonigro, Grace Ispas, David J. Rademacher & Edward M. Campbell
Article: 1789326
Published online: 17 Jul 2020
AbstractforCargo and cell-specific differences in extracellular vesicle populations identified by multiplexed immunofluorescent analysis | Full Text | References | PDF (11.4 MB) | Supplemental
  • 2782 Views
  • 21 CrossRef citations
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Research Article

Article
Metabolic characteristics of large and small extracellular vesicles from pleural effusion reveal biomarker candidates for the diagnosis of tuberculosis and malignancy
Ping Luo, Kaimin Mao, Juanjuan Xu, Feng Wu, Xuan Wang, Sufei Wang, Mei Zhou, Limin Duan, Qi Tan, Guangzhou Ma, Guanghai Yang, Ronghui Du, Hai Huang, Qi Huang, Yumei Li, Mengfei Guo & Yang Jin
Article: 1790158
Published online: 14 Jul 2020
AbstractforMetabolic characteristics of large and small extracellular vesicles from pleural effusion reveal biomarker candidates for the diagnosis of tuberculosis and malignancy | Full Text | References | PDF (9.3 MB) | Supplemental
  • 1713 Views
  • 36 CrossRef citations
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Research article

Article
Lactobacillus plantarum-derived extracellular vesicles induce anti-inflammatory M2 macrophage polarization in vitro
Wanil Kim, Eun Jung Lee, Il-Hong Bae, Kilsun Myoung, Sung Tae Kim, Phil June Park, Kyung-Ha Lee, An Vuong Quynh Pham, Jaeyoung Ko, Sang Ho Oh & Eun-Gyung Cho
Article: 1793514
Published online: 17 Jul 2020
AbstractforLactobacillus plantarum-derived extracellular vesicles induce anti-inflammatory M2 macrophage polarization in vitro | Full Text | References | PDF (5.8 MB) | Supplemental
  • 4667 Views
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Review article

Review Article
How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger
Yu Xiao, Tom Driedonks, Kenneth W. Witwer, Qian Wang & Hang Yin
Article: 1793515
Published online: 15 Jul 2020
AbstractforHow does an RNA selfie work? EV-associated RNA in innate immunity as self or danger | Full Text | References | PDF (1.3 MB)
  • 1193 Views
  • 10 CrossRef citations
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Technical Report

In vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning
Jan Kranich, Nikolaos-Kosmas Chlis, Lisa Rausch, Ashretha Latha, Martina Schifferer, Tilman Kurz, Agnieszka Foltyn-Arfa Kia, Mikael Simons, Fabian J. Theis & Thomas Brocker
Article: 1792683
Published online: 16 Jul 2020
AbstractforIn vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning | Full Text | References | PDF (11.8 MB) | Supplemental
  • 2147 Views
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Research Article

Article
Study of immune-tolerized cell lines and extracellular vesicles inductive environment promoting continuous expression and secretion of HLA-G from semiallograft immune tolerance during pregnancy
Kyoungshik Cho, Hyejin Kook, Suman Kang & Jangho Lee
Article: 1795364
Published online: 20 Jul 2020
AbstractforStudy of immune-tolerized cell lines and extracellular vesicles inductive environment promoting continuous expression and secretion of HLA-G from semiallograft immune tolerance during pregnancy | Full Text | References | PDF (7.6 MB) | Supplemental
  • 4461 Views
  • 7 CrossRef citations
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Article
Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo
Mahmoud Elashiry, Mohamed M. Elashiry, Ranya Elsayed, Mythily Rajendran, Carol Auersvald, Rana Zeitoun, Mohammad H. Rashid, Roxan Ara, Mohamed M. Meghil, Yutao Liu, Ali S. Arbab, Roger M. Arce, Mark Hamrick, Mohammed Elsalanty, Marshall Brendan, Rafal Pacholczyk & Christopher W. Cutler
Article: 1795362
Published online: 07 Aug 2020
AbstractforDendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo | Full Text | References | PDF (5.1 MB) | Supplemental
  • 2371 Views
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Research article

Article
Dendritic cells release exosomes together with phagocytosed pathogen; potential implications for the role of exosomes in antigen presentation
Marthe F. S. Lindenbergh, Richard Wubbolts, Ellen G. F. Borg, Esther M. van ’T Veld, Marianne Boes & W. Stoorvogel
Article: 1798606
Published online: 26 Jul 2020
AbstractforDendritic cells release exosomes together with phagocytosed pathogen; potential implications for the role of exosomes in antigen presentation | Full Text | References | PDF (8.1 MB) | Supplemental
  • 1964 Views
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Review article

Review Article
Systematic review of extracellular vesicle-based treatments for lung injury: are EVs a potential therapy for COVID-19?
Kasra Khalaj, Rebeca Lopes Figueira, Lina Antounians, Giuseppe Lauriti & Augusto Zani
Article: 1795365
Published online: 06 Aug 2020
AbstractforSystematic review of extracellular vesicle-based treatments for lung injury: are EVs a potential therapy for COVID-19? | Full Text | References | PDF (2.3 MB) | Supplemental
  • 3768 Views
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Research article

Article
(Sub)populations of extracellular vesicles released by TNF-α –triggered human endothelial cells promote vascular inflammation and monocyte migration
Baharak Hosseinkhani, Nynke M.S. van den Akker, Daniel G.M. Molin & Luc Michiels
Article: 1801153
Published online: 11 Aug 2020
Abstractfor(Sub)populations of extracellular vesicles released by TNF-α –triggered human endothelial cells promote vascular inflammation and monocyte migration | Full Text | References | PDF (5.1 MB) | Supplemental
  • 2127 Views
  • 28 CrossRef citations
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Article
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging
Dhanu Gupta, Xiuming Liang, Svetlana Pavlova, Oscar P.B Wiklander, Giulia Corso, Ying Zhao, Osama Saher, Jeremy Bost, Antje M. Zickler, Andras Piffko, Cecile L. Maire, Franz L. Ricklefs, Oskar Gustafsson, Virginia Castilla Llorente, Manuela O. Gustafsson, R. Beklem Bostancioglu, Doste R Mamand, Daniel W. Hagey, André Görgens, Joel Z. Nordin & Samir EL Andaloussi
Article: 1800222
Published online: 21 Aug 2020
AbstractforQuantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging | Full Text | References | PDF (4.4 MB) | Supplemental
  • 6825 Views
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Article
Increased small extracellular vesicle secretion after chemotherapy via upregulation of cholesterol metabolism in acute myeloid leukaemia
Chang-Sook Hong, Emily Jeong, Michael Boyiadzis & Theresa L. Whiteside
Article: 1800979
Published online: 07 Aug 2020
AbstractforIncreased small extracellular vesicle secretion after chemotherapy via upregulation of cholesterol metabolism in acute myeloid leukaemia | Full Text | References | PDF (1.7 MB) | Supplemental
  • 1425 Views
  • 20 CrossRef citations
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Article
Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells
Liangzhi Gong, Bi Chen, Juntao Zhang, Yongjin Sun, Ji Yuan, Xin Niu, Guowen Hu, Yu Chen, Zongping Xie, Zhifeng Deng, Qing Li & Yang Wang
Article: 1800971
Published online: 10 Aug 2020
AbstractforHuman ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells | Full Text | References | PDF (6.2 MB) | Supplemental
  • 1952 Views
  • 33 CrossRef citations
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Article
Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles
Thomas E. Whittaker, Anika Nagelkerke, Valeria Nele, Ulrike Kauscher & Molly M. Stevens
Article: 1807674
Published online: 26 Aug 2020
AbstractforExperimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles | Full Text | References | PDF (10.2 MB) | Supplemental
  • 3854 Views
  • 45 CrossRef citations
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Article
A combined “eat me/don’t eat me” strategy based on extracellular vesicles for anticancer nanomedicine
Zakia Belhadj, Bing He, Hailiang Deng, Siyang Song, Hua Zhang, Xueqing Wang, Wenbing Dai & Qiang Zhang
Article: 1806444
Published online: 19 Aug 2020
AbstractforA combined “eat me/don’t eat me” strategy based on extracellular vesicles for anticancer nanomedicine | Full Text | References | PDF (4.8 MB) | Supplemental
  • 3989 Views
  • 115 CrossRef citations
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Article
Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection
Carina Conzelmann, Rüdiger Groß, Min Zou, Franziska Krüger, André Görgens, Manuela O Gustafsson, Samir El Andaloussi, Jan Münch & Janis A. Müller
Article: 1808281
Published online: 24 Aug 2020
AbstractforSalivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection | Full Text | References | PDF (13 MB) | Supplemental
  • 2551 Views
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Research Article

Article
Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer
Ping Wei, Fei Wu, Bin Kang, Xiaohua Sun, Fabienne Heskia, Alexandre Pachot, Ji Liang & Dawei Li
Article: 1809765
Published online: 26 Aug 2020
AbstractforPlasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer | Full Text | References | PDF (3 MB) | Supplemental
  • 3339 Views
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Meeting Report

Meeting Report
The future of Extracellular Vesicles as Theranostics – an ISEV meeting report
Carolina Soekmadji, Bo Li, Yiyao Huang, Haifang Wang, Taixue An, Chunchen Liu, Weilun Pan, Jing Chen, Lesley Cheung, Juan Manuel Falcon-Perez, Yong Song Gho, Harry B. Holthofer, Minh T. N. Le, Antonio Marcilla, Lorraine O’Driscoll, Faezeh Shekari, Tang Long Shen, Ana Claudia Torrecilhas, Xiaomei Yan, Fuquan Yang, Hang Yin, Yu Xiao, Zezhou Zhao, Xue Zou, Qian Wang & Lei Zheng
Article: 1809766
Published online: 04 Sep 2020
AbstractforThe future of Extracellular Vesicles as Theranostics – an ISEV meeting report | Full Text | References | PDF (354.8 KB)
  • 3156 Views
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Research article

Article
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake
Santra Brenna, Hermann C. Altmeppen, Behnam Mohammadi, Björn Rissiek, Florence Schlink, Peter Ludewig, Christoph Krisp, Hartmut Schlüter, Antonio Virgilio Failla, Carola Schneider, Markus Glatzel, Berta Puig & Tim Magnus
Article: 1809065
Published online: 27 Aug 2020
AbstractforCharacterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake | Full Text | References | PDF (7.1 MB) | Supplemental
  • 2319 Views
  • 35 CrossRef citations
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Article
Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties
Raghavendra Upadhya, Leelavathi N. Madhu, Sahithi Attaluri, Daniel Leite Góes Gitaí, Marisa R Pinson, Maheedhar Kodali, Geetha Shetty, Gabriele Zanirati, Smrithi Kumar, Bing Shuai, Susan T Weintraub & Ashok K. Shetty
Article: 1809064
Published online: 26 Aug 2020
AbstractforExtracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties | Full Text | References | PDF (12.5 MB) | Supplemental
  • 4635 Views
  • 81 CrossRef citations
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Article
Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies
Hui Li, Itziar Pinilla-Macua, Yingshi Ouyang, Elena Sadovsky, Kazuhiro Kajiwara, Alexander Sorkin & Yoel Sadovsky
Article: 1812261
Published online: 28 Aug 2020
AbstractforInternalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies | Full Text | References | PDF (6.7 MB) | Supplemental
  • 1615 Views
  • 21 CrossRef citations
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Article
Fusion protein engineered exosomes for targeted degradation of specific RNAs in lysosomes: a proof-of-concept study
Zhelong Li, Xueying Zhou, Xiaotong Gao, Danna Bai, Yan Dong, Wenqi Sun, Lianbi Zhao, Mengying Wei, Xuekang Yang, Guodong Yang & Lijun Yuan
Article: 1816710
Published online: 06 Sep 2020
AbstractforFusion protein engineered exosomes for targeted degradation of specific RNAs in lysosomes: a proof-of-concept study | Full Text | References | PDF (6.1 MB) | Supplemental
  • 2331 Views
  • 28 CrossRef citations
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Review Article

Review Article
Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration
Joshua A. Welsh, Edwin van der Pol, Britta A. Bettin, David R. F. Carter, An Hendrix, Metka Lenassi, Marc-André Langlois, Alicia Llorente, Arthur S. van de Nes, Rienk Nieuwland, Vera Tang, Lili Wang, Kenneth W. Witwer & Jennifer C. Jones
Article: 1816641
Published online: 24 Sep 2020
AbstractforTowards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration | Full Text | References | PDF (14.3 MB)
  • 2834 Views
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Correction

Correction
Correction
Article: i
Published online: 17 Apr 2020
CitationforCorrection | Full Text | PDF (245.8 KB)
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Free Access

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