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Abstract
A simple integrated agarose microchip-based substrate is reported for surface enhanced Raman spectroscopy. The substrate was evaluated for the determination of sodium thiocyanate in milk. The limit of detection was 5 × 10−7 grams per milliliter. The microarray design allowed the synchronous processing of many samples. The reported procedure is green and practical for on-site determination of sodium thiocyanate in milk with potential for additional applications.