Synthesis and Fluorescence of N,N,N‐Trimethyl‐2‐[methyl(7‐nitrobenzo[c][l,2,5]oxadiazol‐4‐yl) amino]ethanaminium Iodide, a pH‐Insensitive Reporter of Organic Cation Transport

Bhasker Reddy Aavula Department of Chemistry, University of Arizona, Tucson, Arizona, USA

M. Ahad Ali Department of Chemistry, University of Arizona, Tucson, Arizona, USA

Eugene A. Mash Department of Chemistry, University of Arizona, Tucson, Arizona, USACorrespondence[email protected]

Dallas Bednarczyk Department of Physiology, University of Arizona, Tucson, Arizona, USA

Stephen H. Wright Department of Physiology, University of Arizona, Tucson, Arizona, USA

Abstract

A synthesis of the title compound, its characterization, and the pH dependence of its fluorescence properties are described. This compound serves as a pH‐insensitive real‐time reporter of organic cation transport in biological systems.

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Acknowledgment

This research was supported in part by National Institutes of Health Awards DK49222, ES06694, and HL07249.

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Synthesis and Fluorescence of N,N,N‐Trimethyl‐2‐[methyl(7‐nitrobenzo[c][l,2,5]oxadiazol‐4‐yl) amino]ethanaminium Iodide, a pH‐Insensitive Reporter of Organic Cation Transport

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Synthesis and Fluorescence of N,N,N‐Trimethyl‐2‐[methyl(7‐nitrobenzo[c][l,2,5]oxadiazol‐4‐yl) amino]ethanaminium Iodide, a pH‐Insensitive Reporter of Organic Cation Transport

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