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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 6
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Original Articles

Synthesis and Fluorescence of N,N,N‐Trimethyl‐2‐[methyl(7‐nitrobenzo[c][l,2,5]oxadiazol‐4‐yl) amino]ethanaminium Iodide, a pH‐Insensitive Reporter of Organic Cation Transport

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Pages 701-705 | Received 15 Sep 2005, Published online: 16 Aug 2006

References

  • Zhang , J. , Campbell , R. E. , Ting , A. Y. and Tsien , R. Y. 2002 . Creating new fluorescent probes for cell biology . Nat. Rev. Mol. Cell. , 3 : 906 – 918 .
  • Tsien , R. Y. 2005 . Building and breeding molecules to spy on cells and tumors . FEBS Lett. , 579 : 927 – 932 .
  • Gekle , M. , Mildenberger , S. , Sauvant , C. , Bednarczyk , D. , Wright , S. H. and Dantzler , W. H. 1999 . Inhibition of initial transport rate of basolateral organic anion carrier in renal PT by BK and phenylephrine . Am. J. Physiol. , 277 : F25 – F256 .
  • Miller , D. S. and Pritchard , J. B. 1993 . Analysis of organic anion (fluorescein, FL) compartmentation within renal cells . FASEB J. , 7 : A456
  • Sullivan , L. P. , Grantham , J. A. , Rome , L. , Wallace , D. and Grantham , J. J. 1990 . Fluorescein transport in isolated proximal tubules in vitro: Epifluorometric analysis . Am. J. Physiol. , 258 : F46 – F51 .
  • Welborn , J. R. , Shpun , S. , Dantzler , W. H. and Wright , S. H. 1998 . Effect of α‐ketoglutarate on organic anion transport in single rabbit renal proximal tubules . Am. J. Physiol. , 274 : F165 – F174 .
  • Miller , D. S. , Villalobos , A. R. and Pritchard , J. B. 1999 . Organic cation transport in rat choroid plexus cells studied by fluorescence microscopy . Am. J. Physiol. , 276 : C955 – C968 .
  • Stachon , A. , Schlatter , E. and Hohage , H. 1996 . Dynamic monitoring of organic cation transport processes by fluorescence measurements in LLC‐PK1 cells . Cell Physiol. Biochem. , 6 : 72 – 81 .
  • Bednarczyk , D. , Mash , E. A. , Aavula , B. R. and Wright , S. H. 2000 . NBD‐TMA: A novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules . Pflügers Arch—Eur. J. Physiol. , 440 : 184 – 192 .
  • Cottrell , G. T. , Lin , R. , Warn‐Cramer , B. J. , Lau , A. F. and Burt , J. M. 2000 . Mechanism of v‐Src‐ and mitogen‐activated protein kinase‐induced reduction of gap junction communication . Am. J. Physiol. Cell Physiol. , 284 : C511 – C520 .
  • Cottrell , G. T. , Wu , Y. and Burt , J. M. 2002 . C×40 and C×43 expression ratio influences heteromeric heterotypic gap junction channel properties . Am. J. Physiol. Cell Physiol. , 282 : C1469 – C1482 .
  • Ek‐Vitorin , J. F. and Burt , J. M. 2005 . Quantification of gap junction selectivity . Am. J. Physiol. Cell Physiol. , 289 : C1535 – C1546 .
  • Zhang , X. , Shirahatti , N. Y. , Mahadevan , D. and Wright , S. H. 2005 . A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2) . J. Biol. Chem. , 280 : 34813 – 34822 .
  • Li , Y. and Mash , E. A. , eds. “ Replacement of the anilinic proton of 1 with a phenyl group kills the fluorescence of the molecule ” . unpublished work, University of Arizona .
  • Callan , J. F. , de Silva , A. P. , Ferguson , J. , Huxley , A. J.M. and O'Brien , A. M. 2004 . Fluorescent photonic devices with two receptors and two switching mechanisms: Applications to pH sensors and implications for metal ion detection . Tetrahedron , 60 : 11125 – 11131 .
  • Xiao , Y. and Qian , X. 2003 . Novel highly efficient fluoroionophores with a peri‐effect and strong electron‐donation receptors: TICT‐promoted PET and signaling response to transition metal cations with low background emission . Tetrahedron Lett. , 44 : 2087 – 2091 .
  • Kolonis , N. , Clayton , A. H.A. , Voss , E. W. Jr. and Sawyer , W. H. 1998 . Spectral properties of fluorescein in solvent–water mixtures: Applications as a probe of hydrogen bonding environments in biological systems . Photochem. Photobiol. , 67 : 500 – 510 .

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