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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 20
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Articles

A simple method for the synthesis of sulfonic esters

, , &
Pages 3133-3148 | Received 25 Apr 2020, Published online: 21 Jul 2020
 

Abstract

An efficient and simple approach for the direct synthesis of aryl and heteroaryl sulfonic esters was developed using DMS and DES as alkoxysulfonylation reagents. The reaction is operationally simple and scalable. This protocol does not require solvent, expensive catalysts, base, ligand additives or other reagents. A wide range of sulfonic esters were synthesized in moderate to good chemical yields. This method has the advantage of low cost, facile and tolerated a wide range of substrates.

Graphical Abstract

Acknowledgments

The authors are grateful to Suven Life Sciences management for allowing us to publish these results.

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