http://orcid.org/0000-0001-7740-8766
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Abstract
A hybrid hydrogel combining collagen and chitosan (Ch) and human amniotic membranes (AM) were produced. To produce hybrid hydrogels, a fixed concentration of chitosan (2%) was used, adding AM as a booster at the concentrations of 2.5, 5.0. and 10.0% (w/w). DSC curves showed the denaturation of collagen. The swelling capacity of hydrogels ranged between 333 ± 19% and 368 ± 28%. The groups Ch-1.0 mg/mL and Ch-2.0 mg/mL had an elastic modulus 27% higher than the other groups.
Graphical Abstract
Disclosure statement
The authors declare that there is no conflict of interest.
Additional information
Funding
This work was supported by the Sao Paulo Research Foundation (FAPESP) under Grant [16/01584-4] and National Council for Scientific and Technological Development (CNPq) under Grant [303752/2017-3].