The Chemistry of Eukaryotic Messenger RNA

Tsujiaki Hata Department of Life Chemistry, Tokyo Institute of Technology, Nagatsuta, Midoriku, Yokohama

Mitsuo Sekine Department of Life Chemistry, Tokyo Institute of Technology, Nagatsuta, Midoriku, Yokohama

Kin-Ichiro Miura Department of Industrial Chemistry, The Univeristy of Tokyo, Hongo 6-3-1, Bunkyoku, Tokyo

Abstract

The so-called “cap” structure of the 5′-terminus of eukaryotic messenger RNA (mRNA) is of importance for protein biosynthesis on ribosimes. We have examined the chemical synthesis and structural requirement of the 5′-terminus of mRNA.

This paper describes a brief summary of the synthesis of the cap structure and the 5′-terminus of mRNA bearing the leader sequences.

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The Chemistry of Eukaryotic Messenger RNA

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The Chemistry of Eukaryotic Messenger RNA

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