Nucleosides, Nucleotides & Nucleic Acids, Volume 6, Issue 1-2 (1987)

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Nucleosides and Nucleotides, Volume 6, Issue 1-2 (1987)

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Miscellany

Foreword
Pages: xiii-xiv
Published online: 05 Dec 2006
CitationforForeword | PDF (43 KB)
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PLENARY LECTURES

Article
The Introduction of C-Substitutents into Pyrimidine- and Purine-Nucleosides
Helmut Vorbrüggen & Konrad Krolikiewicz
Pages: 3-9
Published online: 05 Dec 2006
AbstractforThe Introduction of C-Substitutents into Pyrimidine- and Purine-Nucleosides | References | PDF (197.8 KB)
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Article
Synthesis and Application of Isosteric Purine 2′-Deoxyribofuranosides
Frank Seela, Uwe Bindig, Hansjürgen Driller, Wilhelm Herdering, Klaus Kaiser, Andreas Kehne, Helmut Rosemeyer & Herbert Steker
Pages: 11-23
Published online: 05 Dec 2006
AbstractforSynthesis and Application of Isosteric Purine 2′-Deoxyribofuranosides | References | PDF (421.4 KB)
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Article
Electrochemical Oxidations of Some Purine Nucleosides. Formation of Some Novel Purine Oligonucleosides
P. Subramanian, S. K. Tyagi & Glenn Dryhurst
Pages: 25-42
Published online: 05 Dec 2006
AbstractforElectrochemical Oxidations of Some Purine Nucleosides. Formation of Some Novel Purine Oligonucleosides | References | PDF (625.6 KB)
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Article
Anomalously Coupled Nucleosides
Erik B. Pedersen
Pages: 43-51
Published online: 05 Dec 2006
AbstractforAnomalously Coupled Nucleosides | References | PDF (307.2 KB)
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Article
Fluorine Substituted Analogs of Nucleosides and Nucleotides
Don Bergstrom, Eric Romo & Patrick Shum
Pages: 53-63
Published online: 05 Dec 2006
AbstractforFluorine Substituted Analogs of Nucleosides and Nucleotides | References | PDF (358.5 KB)
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Article
Systematic Synthesis and Biological Evaluation of α - and β-D-Xylo- and Lyxofuranonucleosides of the Five Naturally Occurring Nucleic Acid Bases
G. Gosselin, M. C. Bergogne, J. L. Imbach, J. De Rudder & E. De Clercq
Pages: 65-72
Published online: 05 Dec 2006
AbstractforSystematic Synthesis and Biological Evaluation of α - and β-D-Xylo- and Lyxofuranonucleosides of the Five Naturally Occurring Nucleic Acid Bases | References | PDF (288.4 KB)
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Article
New Substrate Analogues as Inhibitors of S-Adenosylmetfflonine Decarboxylase
John A. Secrist
Pages: 73-83
Published online: 05 Dec 2006
AbstractforNew Substrate Analogues as Inhibitors of S-Adenosylmetfflonine Decarboxylase | References | PDF (414.4 KB)
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Article
The Synthesis, Mutagenic and Pharmacological Activities of 2-Carbon-Substituted Adenosines
Akira Matsuda & Tohru Ueda
Pages: 85-94
Published online: 05 Dec 2006
AbstractforThe Synthesis, Mutagenic and Pharmacological Activities of 2-Carbon-Substituted Adenosines | References | PDF (348.1 KB)
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Article
Triciribine (TCN), A Novel Tricyclic Adenosine Analog with Anticancer Activity
Linda L. Wotring, Joseph L. Roti, Jerry L. Hudson, Joan E. Passiatore, Katherine Z. Borysko, Richard D. Newcomb & Leroy B. Townsend
Pages: 95-109
Published online: 05 Dec 2006
AbstractforTriciribine (TCN), A Novel Tricyclic Adenosine Analog with Anticancer Activity | References | PDF (514.5 KB)
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Article
DNA-Triesters - The Synthesis and Absolute Configuration Assignments at P-Stereogenic Centres
Piotr Guga, Maria Koziołkiewicz, Andrzej Okruszek, Bogdan Uznański & Wojciech J. Stec
Pages: 111-119
Published online: 05 Dec 2006
AbstractforDNA-Triesters - The Synthesis and Absolute Configuration Assignments at P-Stereogenic Centres | References | PDF (411.1 KB)
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Article
The Problem of 2′-Protection in Rapid Oligoribonucleotide Synthesis
Colin B. Reese
Pages: 121-129
Published online: 05 Dec 2006
AbstractforThe Problem of 2′-Protection in Rapid Oligoribonucleotide Synthesis | References | PDF (379.1 KB)
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Article
The Chemistry of Eukaryotic Messenger RNA
Tsujiaki Hata, Mitsuo Sekine & Kin-Ichiro Miura
Pages: 131-136
Published online: 05 Dec 2006
AbstractforThe Chemistry of Eukaryotic Messenger RNA | References | PDF (239.5 KB)
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Article
Semi-Mechanized Simultaneous Synthesis of Multiple Oligonucleotide Fragments
H. Seliger, A. Herold, U. Kotschi, J. Lyons, G. Schmidt & F. Eisenbeiß
Pages: 137-146
Published online: 05 Dec 2006
AbstractforSemi-Mechanized Simultaneous Synthesis of Multiple Oligonucleotide Fragments | References | PDF (407.6 KB)
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Article
Phosphonylmethyl Analogs of Nucleotides and Their Derivatives: Chemistry and Biology
Antonin Holy
Pages: 147-155
Published online: 05 Dec 2006
AbstractforPhosphonylmethyl Analogs of Nucleotides and Their Derivatives: Chemistry and Biology | References | PDF (360.8 KB)
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Article
Versatile Oligonucleotides: B DNA, Z DNA, and DNA Hairpins as Seen in Aqueous Solution by Two-Dimensional NMR
Cornells Altona
Pages: 157-172
Published online: 05 Dec 2006
AbstractforVersatile Oligonucleotides: B DNA, Z DNA, and DNA Hairpins as Seen in Aqueous Solution by Two-Dimensional NMR | References | PDF (702.1 KB)
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Article
Phosphorothioate Analogs of 2–5A: Elucidation of the Stereochemical Course of the Enzymes of the 2–5A Synthetase/RNase L System
Katalin Karikó, Shu Wu Li, Robert W. Sobol Jr., Lorraine Suhadolnik, Nancy L. Reichenbach, Robert J. Suhadolnik, Ramamurthy Charubala & Wolfgang Pfleiderer
Pages: 173-184
Published online: 05 Dec 2006
AbstractforPhosphorothioate Analogs of 2–5A: Elucidation of the Stereochemical Course of the Enzymes of the 2–5A Synthetase/RNase L System | References | PDF (482.4 KB)
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Article
Chemoenzymatic Gene Synthesis of A Gene for Human Growth Hormone Releasing Hormone (hGHRH), its Expression in E. Coli and Enzymatic Amidation
Joachim W. Engels, Jan Glauder, Hubert Mülliner, Eugen Uhlmann, Waldemar Wetekam, T. Hashimoto Gotoh & Barbara Scheikl-lenz
Pages: 185-195
Published online: 05 Dec 2006
AbstractforChemoenzymatic Gene Synthesis of A Gene for Human Growth Hormone Releasing Hormone (hGHRH), its Expression in E. Coli and Enzymatic Amidation | References | PDF (444 KB)
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Article
Targets for the Antiviral Activity of Pyrimidine and Purine Nucleoside Analogues
Erik De Clercq
Pages: 197-207
Published online: 05 Dec 2006
AbstractforTargets for the Antiviral Activity of Pyrimidine and Purine Nucleoside Analogues | References | PDF (498 KB)
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Article
A Convergent Regiospecific Synthesis of the Lariat-Trinucleotides and A2′p 5′G and A2′p 5′G3′p 5′C from A O4-2-Nitrophenyl) -Uridine Building Block
J-M. Vial, N. Balgobin, G. Remaud, A. Nyilas & J. Chattopadhyaya
Pages: 209-226
Published online: 05 Dec 2006
AbstractforA Convergent Regiospecific Synthesis of the Lariat-Trinucleotides and A2′p 5′G and A2′p 5′G3′p 5′C from A O4-2-Nitrophenyl) -Uridine Building Block | References | PDF (616 KB)
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COMMUNICATIONS

Article
Synthetic Approaches to Rare 2-Substituted Purine Nucleosides
Vasu Nair, Stanley D. Chamberlain, Raymond Desilvia & Greg S. Buenger
Pages: 229-232
Published online: 05 Dec 2006
AbstractforSynthetic Approaches to Rare 2-Substituted Purine Nucleosides | References | PDF (124.9 KB)
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Article
A Novel Approach to Khantiokerically Pure Carbocyclic Nucleoside Analogues
Michael Bodenteich, Kurt Faber, Gerhard Penn And & Herfried Griengl
Pages: 233-237
Published online: 05 Dec 2006
AbstractforA Novel Approach to Khantiokerically Pure Carbocyclic Nucleoside Analogues | References | PDF (198.4 KB)
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Article
Synthesis of 2′,3′-Dideoxycyclopentenyl Carbocyclic Nucleosides as Potential Drugs for the Treatment of AIDS
Victor E. Marquez, Christopher K.H. Tseng, Susan P. Treanor & John S. Driscoll
Pages: 239-244
Published online: 05 Dec 2006
AbstractforSynthesis of 2′,3′-Dideoxycyclopentenyl Carbocyclic Nucleosides as Potential Drugs for the Treatment of AIDS | References | PDF (200 KB)
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Article
Synthesis and Biological Evaluation of 3-Chloro-4-(D-Ribofuranosyl)-Pyridine and 3-(D-Ribofuranosyl)-2- Pyridone
M. Belmans, I. Vrijens, E. L. Esmans, J. A. Lepoivre, F. C. Alderweireldt, L. L. Wotring & L. B. Townsend
Pages: 245-248
Published online: 05 Dec 2006
AbstractforSynthesis and Biological Evaluation of 3-Chloro-4-(D-Ribofuranosyl)-Pyridine and 3-(D-Ribofuranosyl)-2- Pyridone | References | PDF (116.1 KB)
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Article
Synthesis and Antitumor Activities of 5-Fluorouracil Derivatives
S. Ozaki, Y. Watanabe, T. Nagase, T. Ogasawara, S. Ahmad, A. Hoshi & M. Iigo
Pages: 249-256
Published online: 05 Dec 2006
AbstractforSynthesis and Antitumor Activities of 5-Fluorouracil Derivatives | References | PDF (242.4 KB)
  • 21 Views
  • 3 CrossRef citations
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Article
Synthesis and Biological Properties of 6-Substituted 5-Fluorouridines
K. Felczak, T. Kulikowski, J. A. Vilpo, J. Giziewicz & D. Shugar
Pages: 257-260
Published online: 05 Dec 2006
AbstractforSynthesis and Biological Properties of 6-Substituted 5-Fluorouridines | References | PDF (165.9 KB)
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Article
Direct Synthesis of Pyrrole Nucleosides by the Stereospecific Sodium Salt Glycosylation Procedure
G. R. Revankar, K. Ranasamy & R. K. Robins
Pages: 261-264
Published online: 05 Dec 2006
AbstractforDirect Synthesis of Pyrrole Nucleosides by the Stereospecific Sodium Salt Glycosylation Procedure | References | PDF (167 KB)
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Article
Synthesis of 6β-Hydroxyaristeromycin - A Novel Type of Carbocyclic Nucleoside Analogue
Azzouz Ben Cheikh & Jiří Žmlićka
Pages: 265-268
Published online: 05 Dec 2006
AbstractforSynthesis of 6β-Hydroxyaristeromycin - A Novel Type of Carbocyclic Nucleoside Analogue | References | PDF (137.5 KB)
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Article
A New Method of Synthesis of 4-N-Alkyl Substituted Cytosine Derivatives Via 4-N-Arylsulfonyl or Alkylsulfonyl Intermediates
W. T. Markiewicz, R. Kierzek & B. Hemes
Pages: 269-272
Published online: 05 Dec 2006
AbstractforA New Method of Synthesis of 4-N-Alkyl Substituted Cytosine Derivatives Via 4-N-Arylsulfonyl or Alkylsulfonyl Intermediates | References | PDF (147.5 KB)
  • 30 Views
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Article
O6-Protection and Other Transformations at Guanosine and Inosine Lactam Sites with Application of Related Pyridinium Salts
S. Mielewczyk, Z. Gdaniec, G. Bobrowska & R. W. Adamiak
Pages: 273-277
Published online: 05 Dec 2006
AbstractforO6-Protection and Other Transformations at Guanosine and Inosine Lactam Sites with Application of Related Pyridinium Salts | References | PDF (238.6 KB)
  • 25 Views
  • 5 CrossRef citations
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Article
Phosphotriester Synthesis of Oligonucleotides with the Use of N- and O-Nucleophilic Intramolecular Catalysis
V. A. Efimov, A. A. Buryakova, N. N. Polushin, I. Y. Dubey, O. G. Chakhmakhcheva & Yu. A. Ovchinnikov
Pages: 279-282
Published online: 05 Dec 2006
AbstractforPhosphotriester Synthesis of Oligonucleotides with the Use of N- and O-Nucleophilic Intramolecular Catalysis | References | PDF (192.5 KB)
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  • 3 CrossRef citations
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Article
Studies on the Synthesis of Oligonucleotides via the Hydrogenphosphonate Approach
Per J. Garegg, Tor Regberg, Jacek Stawinski & Roger Stromberg
Pages: 283-286
Published online: 05 Dec 2006
AbstractforStudies on the Synthesis of Oligonucleotides via the Hydrogenphosphonate Approach | References | PDF (165.5 KB)
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Article
The Use of Nucleoside H-Phosphonates in the Synthesis of Deoxyoligonucleotides
Brian C. Froehler & Mark D. Matteucci
Pages: 287-291
Published online: 05 Dec 2006
AbstractforThe Use of Nucleoside H-Phosphonates in the Synthesis of Deoxyoligonucleotides | References | PDF (167 KB)
  • 59 Views
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Article
Use of the 2-(2-Pyridyl)Ethyl Protecting Group in the Synthesis of DNA Fragments via Phosphoramidite Intermediates
Hiroshi Takaku, Tetsuo Watanabe & Shoji Hamamoto
Pages: 293-296
Published online: 05 Dec 2006
AbstractforUse of the 2-(2-Pyridyl)Ethyl Protecting Group in the Synthesis of DNA Fragments via Phosphoramidite Intermediates | References | PDF (193.2 KB)
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Article
Base Modification and the Phosphoramidite Approach
L. J. McBride, J. S. Eadie, J. W. Efcavitch & W. A. Andrus
Pages: 297-300
Published online: 05 Dec 2006
AbstractforBase Modification and the Phosphoramidite Approach | References | PDF (187.6 KB)
  • 31 Views
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Article
Quantitative Measurements of Modified Thymine Residues in DNA Chains Formic Acid Hydrolysis
R. Téoule & A. Guy
Pages: 301-305
Published online: 05 Dec 2006
AbstractforQuantitative Measurements of Modified Thymine Residues in DNA Chains Formic Acid Hydrolysis | References | PDF (160.1 KB)
  • 13 Views
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Article
Specific Enzymes Degrading Diadenosine Tetraphosphate (Ap4 A). Promising Targets for Selective Drugs to be Designed
Andrzej Guranowski, Katedra Biochemii & Akademia Rolnicza
Pages: 307-310
Published online: 05 Dec 2006
AbstractforSpecific Enzymes Degrading Diadenosine Tetraphosphate (Ap4 A). Promising Targets for Selective Drugs to be Designed | References | PDF (260.3 KB)
  • 13 Views
  • 1 CrossRef citations
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Article
Biological Activities of Oligonucleotides Linked to Poly(L-Lysine)
M. Lemaltre, C. Bisbal, B. Bayard & B. Lebleu
Pages: 311-315
Published online: 05 Dec 2006
AbstractforBiological Activities of Oligonucleotides Linked to Poly(L-Lysine) | References | PDF (196.4 KB)
  • 17 Views
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Article
Base Analogue Interactions in DNA Duplexes
D. M. Brown, N. N. Anand & S. A. Salisbury
Pages: 317-320
Published online: 05 Dec 2006
AbstractforBase Analogue Interactions in DNA Duplexes | References | PDF (137.5 KB)
  • 9 Views
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Article
Versatile Methodology for the Construction of Artificial Genes
O. G. Chakhmakhcheva, V. A. Efimov & Yu. A. Ovchinnikov
Pages: 321-325
Published online: 05 Dec 2006
AbstractforVersatile Methodology for the Construction of Artificial Genes | References | PDF (211.4 KB)
  • 10 Views
  • 5 CrossRef citations
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Article
DNA Base Pair Binding Specificity of CC-1065
Nicole Y. Thériault, William C. Krueger & Mark D. Prairie
Pages: 327-330
Published online: 05 Dec 2006
AbstractforDNA Base Pair Binding Specificity of CC-1065 | References | PDF (185.9 KB)
  • 12 Views
  • 1 CrossRef citations
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Article
Site-Directed Mutagenesis of Stahphylococcal Nuclease: Role of Tyrosine Residues in Substrate Binding and Catalysis
E. Uhlmann & J. A. Smith
Pages: 331-334
Published online: 05 Dec 2006
AbstractforSite-Directed Mutagenesis of Stahphylococcal Nuclease: Role of Tyrosine Residues in Substrate Binding and Catalysis | References | PDF (130.8 KB)
  • 9 Views
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Article
Solid Supported Chemical 5′-Phosphorylation of Oligodeoxy-Ribonucleotides that can be Monitored by Trityl Cation Releasi Application to Gene Synthesis
Thomas Horn, Judith S. Allen & Mickey S. Urdea
Pages: 335-340
Published online: 05 Dec 2006
AbstractforSolid Supported Chemical 5′-Phosphorylation of Oligodeoxy-Ribonucleotides that can be Monitored by Trityl Cation Releasi Application to Gene Synthesis | References | PDF (218.8 KB)
  • 27 Views
  • 11 CrossRef citations
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Article
A New 5′-Protecting Group for Use in Solid-Phase Synthesis of Oligoribonucleotides
Chris Christodoulou, Sudhir Agrawal & Michael J. Gait
Pages: 341-344
Published online: 05 Dec 2006
AbstractforA New 5′-Protecting Group for Use in Solid-Phase Synthesis of Oligoribonucleotides | References | PDF (162.9 KB)
  • 27 Views
  • 9 CrossRef citations
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Article
New Approach to the Synthesis of 2′(3′)-O-Aminoacyloligoribonucleotides Related to the 3′-Terminus of Aminoacyl Transfer Ribonucleic Acid
C. Scalfi-happ, E. Happ & S. Chladek
Pages: 345-348
Published online: 05 Dec 2006
AbstractforNew Approach to the Synthesis of 2′(3′)-O-Aminoacyloligoribonucleotides Related to the 3′-Terminus of Aminoacyl Transfer Ribonucleic Acid | References | PDF (142.5 KB)
  • 19 Views
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Article
Synthesis Of Oligodeoxyribonucleotides Containing an Aliphatic Amino Linker Arm at Selected Adenine Bases and Derivatization with Biotin
Jean-Paul Roduit, Jeffrey Shaw, Angelika Chollet & André Chollet
Pages: 349-352
Published online: 05 Dec 2006
AbstractforSynthesis Of Oligodeoxyribonucleotides Containing an Aliphatic Amino Linker Arm at Selected Adenine Bases and Derivatization with Biotin | References | PDF (179.5 KB)
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Article
Transition Metal Complexes of 5-Amino-1-β-D-Ribofuranosylimidazole-4-Carboxylic Acid 5′-Phosphate, an Intermediate in the de novo Biosynthesis of Purine Nucleotides: Synthesis and Effects on Enzyme Activity
J. R. Chipperfield, R. W. Humble, G. Iveson, K. Kadir, G. Mackenzie & G. Shaw
Pages: 353-358
Published online: 05 Dec 2006
AbstractforTransition Metal Complexes of 5-Amino-1-β-D-Ribofuranosylimidazole-4-Carboxylic Acid 5′-Phosphate, an Intermediate in the de novo Biosynthesis of Purine Nucleotides: Synthesis and Effects on Enzyme Activity | References | PDF (234.8 KB)
  • 12 Views
  • 3 CrossRef citations
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Article
Polyfunctional O-Substituted Hydroxylamines: Modification of Nucleic Acids, Inhibition of Sam-Decarboxylase
A. R. Khomutov, A. M. Kritsky, E. Yu. Artamonova & R. M. Khomutov
Pages: 359-362
Published online: 05 Dec 2006
AbstractforPolyfunctional O-Substituted Hydroxylamines: Modification of Nucleic Acids, Inhibition of Sam-Decarboxylase | References | PDF (180.3 KB)
  • 11 Views
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POSTERS

Article
The Preparation and Utility of 5-β-D-Ribofuranosyl-(2H)-Tetrazole as a Key Synthon for C-Nucleoside Chemistry
Joze Kobe, Marija Prhavc, Marijan Hohnjec & Leroy B. Townsend
Pages: 365-368
Published online: 05 Dec 2006
AbstractforThe Preparation and Utility of 5-β-D-Ribofuranosyl-(2H)-Tetrazole as a Key Synthon for C-Nucleoside Chemistry | References | PDF (190.4 KB)
  • 13 Views
  • 6 CrossRef citations
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Article
Regiospecipic Synthesis of a New Cross-Linked Dinucleoside : 1-(N6-Deoxyadenyl)-2-(o4-Thymidyl)-Ethane
M. Nogueras, M. Lucas & J-L. Imbach
Pages: 369-370
Published online: 05 Dec 2006
AbstractforRegiospecipic Synthesis of a New Cross-Linked Dinucleoside : 1-(N6-Deoxyadenyl)-2-(o4-Thymidyl)-Ethane | References | PDF (95.9 KB)
  • 10 Views
  • 1 CrossRef citations
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Article
Intramolecular Transformations Related to the Structures of Allyl Derivatives of Hypoxanthine and Uracil
V. Škari, M. Škarić-Mlakar, M. Jokić & D. Škarić
Pages: 371-372
Published online: 05 Dec 2006
AbstractforIntramolecular Transformations Related to the Structures of Allyl Derivatives of Hypoxanthine and Uracil | References | PDF (98.8 KB)
  • 22 Views
  • 1 CrossRef citations
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Article
Synthesis of 7-Glycopyranosyl-5-oxq-pyrrolo[2,3-d]Pyrimidine and 4-Glyco Pyranosylamino-Furo[2,3-d]Pyrimidine Derivatives
M. Nogueras, M. L. Quijano, A. Sénchez & M. Melgarejo
Pages: 373-374
Published online: 05 Dec 2006
AbstractforSynthesis of 7-Glycopyranosyl-5-oxq-pyrrolo[2,3-d]Pyrimidine and 4-Glyco Pyranosylamino-Furo[2,3-d]Pyrimidine Derivatives | References | PDF (75 KB)
  • 11 Views
  • 2 CrossRef citations
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Article
Glycosides Derived from Pyrazino[2,3-C]-1,2,6-Thiadiazine 2,2-Dioxides
P. Goya, A. Martinez, M. L. Jimeno & W. Pfleiderer
Pages: 375-377
Published online: 05 Dec 2006
AbstractforGlycosides Derived from Pyrazino[2,3-C]-1,2,6-Thiadiazine 2,2-Dioxides | References | PDF (84.2 KB)
  • 10 Views
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Article
A New Method for Synthesizing Acyclonucleosioes
H. B. Lazrek, M. L. Taha, J. L. Barascut & J. L. Imbach
Pages: 379-380
Published online: 05 Dec 2006
AbstractforA New Method for Synthesizing Acyclonucleosioes | References | PDF (69.2 KB)
  • 15 Views
  • 8 CrossRef citations
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Article
Improved Synthesis and Cytostatic Activity of 1-Deazaadenosine
Gloria Cristalli, Palmarisa Franchetti, Mario Grifantini, Sauro Vittori, Teresa Bordoni & Cristina Geroni
Pages: 381-383
Published online: 05 Dec 2006
AbstractforImproved Synthesis and Cytostatic Activity of 1-Deazaadenosine | References | PDF (81.6 KB)
  • 12 Views
  • 1 CrossRef citations
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Article
Transglycosylation of Guanine Nucleosides
Jeratzy Boryski & Bozenna Golankiewicz
Pages: 385-386
Published online: 05 Dec 2006
AbstractforTransglycosylation of Guanine Nucleosides | References | PDF (68.5 KB)
  • 20 Views
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Article
Synthesis of Some Quinolinium Nucleosides
L. Kemps, E. L. Esmans, R. Dommisse, J. A. Lepoivre & F. C. Alderweireldt
Pages: 387-388
Published online: 05 Dec 2006
AbstractforSynthesis of Some Quinolinium Nucleosides | References | PDF (57.4 KB)
  • 14 Views
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Article
One-Step Protection of the Guanine Moiety in 2′-Deoxyguanosine and Guanosine
A. M. A. Pistorius, C. A. A. Claesen, F. J. B. Kremer, E. A. V. Rijk & G. I. Tesser
Pages: 389-390
Published online: 05 Dec 2006
AbstractforOne-Step Protection of the Guanine Moiety in 2′-Deoxyguanosine and Guanosine | References | PDF (79.7 KB)
  • 55 Views
  • 3 CrossRef citations
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Article
Novel Acyclic Analogues of Purine Nucleosides: 2,3-Dihydroxy-1-Methoxypropyl and 3-Hydroxy-1-Methoxypropyl Derivatives
S. Bailey & M. R. Harnden
Pages: 391-392
Published online: 05 Dec 2006
AbstractforNovel Acyclic Analogues of Purine Nucleosides: 2,3-Dihydroxy-1-Methoxypropyl and 3-Hydroxy-1-Methoxypropyl Derivatives | PDF (67.6 KB)
  • 13 Views
  • 3 CrossRef citations
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Article
Facile Synthesis of Base-Labile 2′-Deoxyribonucleosides: An Improved Synthesis of 2′-Deoxy-5-aza-Cytidine
Jean Ben-hattar & Josef Jiricny
Pages: 393-394
Published online: 05 Dec 2006
AbstractforFacile Synthesis of Base-Labile 2′-Deoxyribonucleosides: An Improved Synthesis of 2′-Deoxy-5-aza-Cytidine | References | PDF (78.1 KB)
  • 23 Views
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Article
Deuteration and Tritiation of 2′-Deoxyribonucleosides in the 5′ and 4′ Positions
M. Berger, A. Shaw, J. Cadet & J. R. Jones
Pages: 395-396
Published online: 05 Dec 2006
AbstractforDeuteration and Tritiation of 2′-Deoxyribonucleosides in the 5′ and 4′ Positions | References | PDF (62.7 KB)
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Article
Reactions of Purine Nucleosides with Aqueous Alkalies: The Effect of the C6 Substituent on the Kinetics of the Multistage Pathway
Marri Lönnberg, Pertti Lehikoinen & Rainer Käppi
Pages: 397-398
Published online: 05 Dec 2006
AbstractforReactions of Purine Nucleosides with Aqueous Alkalies: The Effect of the C6 Substituent on the Kinetics of the Multistage Pathway | References | PDF (77.5 KB)
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Article
Amination of Ethyl 5-Amino-1-Qlycofuranosylimidazole-4-Carboxylates Using Trimethylaluminium
A. Grouiller, R. W. Humble, G. Iveson, G. Mackenzie, B. Najib, H. Pacheco & G. Shaw
Pages: 399-400
Published online: 05 Dec 2006
AbstractforAmination of Ethyl 5-Amino-1-Qlycofuranosylimidazole-4-Carboxylates Using Trimethylaluminium | References | PDF (82.6 KB)
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Article
Arylamidation of Purine Nucleosides by 2-Acetylalkoxy- Aminofluorene - an Intramolecular Approach to the Synthesis of Nucleoside - Carcinogen Adducts
A. Leterme, M. F. Lhomme & J. Lhomme
Pages: 401-402
Published online: 05 Dec 2006
AbstractforArylamidation of Purine Nucleosides by 2-Acetylalkoxy- Aminofluorene - an Intramolecular Approach to the Synthesis of Nucleoside - Carcinogen Adducts | References | PDF (80.3 KB)
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Article
Synthesis of 5′-O-Dimeth0Xytrityl-4-N-/6-Trifluoroacetamidohexyl/-2′-Deoxycytidine and its Application in the Synthesis of Biotin-Labeled Oligonucleotides
Ryszard Kierzek & Wojciech T. Markiewicz
Pages: 403-405
Published online: 05 Dec 2006
AbstractforSynthesis of 5′-O-Dimeth0Xytrityl-4-N-/6-Trifluoroacetamidohexyl/-2′-Deoxycytidine and its Application in the Synthesis of Biotin-Labeled Oligonucleotides | References | PDF (107.8 KB)
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Article
Preparative Syntheses of Guanylate-Rich Oligonucleotides Using the Phosphotriester Method in Solution
H. Schott, R. Semmler & K. Cloß
Pages: 407-408
Published online: 05 Dec 2006
AbstractforPreparative Syntheses of Guanylate-Rich Oligonucleotides Using the Phosphotriester Method in Solution | References | PDF (89.6 KB)
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Article
Oligonucleotide Mediated Mutational Analysis of Recognition Sequence Effects on Lariat Formation During Messenger RNA Splicing in Yeast
Eduard Felder, Alessandra Cellini & John Rossi
Pages: 409-411
Published online: 05 Dec 2006
AbstractforOligonucleotide Mediated Mutational Analysis of Recognition Sequence Effects on Lariat Formation During Messenger RNA Splicing in Yeast | References | PDF (113.6 KB)
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Article
Synthesis and Cloning of a Gene Encoding Human Interleukin-1β (IL-1β)
David C. Humber, Michelle Allsopp, Barry A. Coomber, Lucia G. D'urso, Colin W. Dykes, Adrian N. Hobden, Melville Mitchell & Stewart A. Noble
Pages: 413-414
Published online: 05 Dec 2006
AbstractforSynthesis and Cloning of a Gene Encoding Human Interleukin-1β (IL-1β) | References | PDF (95.2 KB)
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Article
5-Hydroxymethyl-2′-Deoxyuridine: Studies of Antileukemic Properties in Vitro and in Vivo
J. A. Vilpo, D. Bergstrom, L. Kangas & E. Suvanto
Pages: 415-417
Published online: 05 Dec 2006
Abstractfor5-Hydroxymethyl-2′-Deoxyuridine: Studies of Antileukemic Properties in Vitro and in Vivo | References | PDF (102.2 KB)
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  • 1 CrossRef citations
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Article
Sequencing of Synthetic DNA Fragments Containing Various 5-Substituted Pyrimidines by Solid-Phase Chemical Degradation Using CCS Paper
Andre Rosenthal
Pages: 419-420
Published online: 05 Dec 2006
AbstractforSequencing of Synthetic DNA Fragments Containing Various 5-Substituted Pyrimidines by Solid-Phase Chemical Degradation Using CCS Paper | References | PDF (112.2 KB)
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Article
Mechanism of Antiviral Activity of 5-Ethyl-2′-Deoxyuridine
Ria Bernaerts & Erik De Clercq
Pages: 421-422
Published online: 05 Dec 2006
AbstractforMechanism of Antiviral Activity of 5-Ethyl-2′-Deoxyuridine | References | PDF (93.2 KB)
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Article
Role of Adenosine Kinase in the Biological (Antiviral and Anticellular) Activities of Adenosine Analogues
Marina Cools, Erik De Clercq & John C. Drach
Pages: 423-424
Published online: 05 Dec 2006
AbstractforRole of Adenosine Kinase in the Biological (Antiviral and Anticellular) Activities of Adenosine Analogues | References | PDF (108.6 KB)
  • 13 Views
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Article
Activation of Nucleoside Hydrogenphosphonates by Use of Aryl Sulfonyl Chlorides
Per J. Garegg, Jacek Stawinski & Roger Strömberg
Pages: 425-427
Published online: 05 Dec 2006
AbstractforActivation of Nucleoside Hydrogenphosphonates by Use of Aryl Sulfonyl Chlorides | References | PDF (87.5 KB)
  • 23 Views
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Article
Studies on the Oxidation of Nucleoside Hydrogenphosphonates
Par J. Garegg, Tor Regberg, Jacek Stawinski & Roger Strömberg
Pages: 429-432
Published online: 05 Dec 2006
AbstractforStudies on the Oxidation of Nucleoside Hydrogenphosphonates | References | PDF (174.2 KB)
  • 49 Views
  • 7 CrossRef citations
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Article
Synthesis and 15N NMR of d[CGT(15N6)ACG] and d[CGT(CGT)(15N1)ACG]
Xiolian Gao & Roger A. Jones
Pages: 433-435
Published online: 05 Dec 2006
AbstractforSynthesis and 15N NMR of d[CGT(15N6)ACG] and d[CGT(CGT)(15N1)ACG] | References | PDF (99.2 KB)
  • 13 Views
  • 3 CrossRef citations
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Article
Hybridization Probes with Deoxyinosine, Deoxyxanthosine or Deoxynebularine at Ambiguous Codon Positions
A. Van Aerschot, B. Peeters & H. Vanderhaeghe
Pages: 437-439
Published online: 05 Dec 2006
AbstractforHybridization Probes with Deoxyinosine, Deoxyxanthosine or Deoxynebularine at Ambiguous Codon Positions | References | PDF (129 KB)
  • 13 Views
  • 6 CrossRef citations
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Article
Synthesis and Activity of Oligonucleotides Containing a Biologically Active Nucleoside at the 2′End
P. Herdewijn, R. Charubala, R. Pauwels, E. De Clercq & W. Pfleiderer
Pages: 441-442
Published online: 05 Dec 2006
AbstractforSynthesis and Activity of Oligonucleotides Containing a Biologically Active Nucleoside at the 2′End | PDF (73.9 KB)
  • 14 Views
  • 3 CrossRef citations
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Article
Synthesis and Biological Activity of 3′-Modified 2′-5′ Adenylate Trimers
P. Herdewijn, R. Charubala, R. Pauwels, E. De Clercq & W. Pfleiderer
Pages: 443-444
Published online: 05 Dec 2006
AbstractforSynthesis and Biological Activity of 3′-Modified 2′-5′ Adenylate Trimers | References | PDF (88.7 KB)
  • 12 Views
  • 4 CrossRef citations
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Article
Easily Available Column Device for Manual Oligonucleotide Synthesis on Solid Support by P(III) Methodology
R. W. Adamiak & F. Cramer
Pages: 445-446
Published online: 05 Dec 2006
AbstractforEasily Available Column Device for Manual Oligonucleotide Synthesis on Solid Support by P(III) Methodology | References | PDF (87.9 KB)
  • 18 Views
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Article
Oligomers Containing 2′-Deoxyinosine Isosteres as Ambiguous Nucleoside or 1,3-Propanediol as Nucleoside Substitute
Frank Seela & Klaus Kaiser
Pages: 447-449
Published online: 05 Dec 2006
AbstractforOligomers Containing 2′-Deoxyinosine Isosteres as Ambiguous Nucleoside or 1,3-Propanediol as Nucleoside Substitute | References | PDF (94.6 KB)
  • 18 Views
  • 7 CrossRef citations
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Article
Phosphoramidites of [180] Chiral (Rp)- and (Sp)-Configurated Dimer-Blocks and their Use in Automated Oligonucleotide Synthesis
F. Seela, A. Kehne, W. Herdering & U. Kretschmer
Pages: 451-456
Published online: 05 Dec 2006
AbstractforPhosphoramidites of [180] Chiral (Rp)- and (Sp)-Configurated Dimer-Blocks and their Use in Automated Oligonucleotide Synthesis | References | PDF (158.9 KB)
  • 17 Views
  • 3 CrossRef citations
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Article
Substituent Influence on the Reaction Rate of Deoxyribonucleoside Phosphoramidites with Deoxyribonucleosides Catalysed by Tetrazole
Bjarne H. Dahl, John Nielsen & Otto Dahl
Pages: 457-460
Published online: 05 Dec 2006
AbstractforSubstituent Influence on the Reaction Rate of Deoxyribonucleoside Phosphoramidites with Deoxyribonucleosides Catalysed by Tetrazole | References | PDF (90.4 KB)
  • 26 Views
  • 7 CrossRef citations
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Article
Solid Phase Synthesis of DNA Under a Non-Depurinating Condition with a Base Labile 5′-Protecting Group (Fmoc) Using Phosphiteamidite Approach
N. Balgobin & J. Chattopadhyaya
Pages: 461-463
Published online: 05 Dec 2006
AbstractforSolid Phase Synthesis of DNA Under a Non-Depurinating Condition with a Base Labile 5′-Protecting Group (Fmoc) Using Phosphiteamidite Approach | References | PDF (106.4 KB)
  • 35 Views
  • 13 CrossRef citations
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Article
Anomeric Mixtures of D-Xylo-and D-Lyxo-Furanonucleosides: Correlations between their Structures and their Retention Times in HPLC Analysis
A. Pompon, G. Gosselin, M. C. Bergogne & J. L. Imbach
Pages: 465-466
Published online: 05 Dec 2006
AbstractforAnomeric Mixtures of D-Xylo-and D-Lyxo-Furanonucleosides: Correlations between their Structures and their Retention Times in HPLC Analysis | References | PDF (87.6 KB)
  • 15 Views
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Article
DNA Apurinic Sites: Synthesis of a Model Compound and Study of its Reactivity with 3-Aminocarbazole
J.-J. Vasseur, B. Rayner, J.-L. Imbach, S. Verla, J. A. McCloskey, J. W. Lown & D. K. Chang
Pages: 467-468
Published online: 05 Dec 2006
AbstractforDNA Apurinic Sites: Synthesis of a Model Compound and Study of its Reactivity with 3-Aminocarbazole | References | PDF (77.3 KB)
  • 14 Views
  • 4 CrossRef citations
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Article
Unexpected Transposition of a Deoxyguanosine Derivative
A.-F. Maggio, M. Lucas, J.-L. Barascut & J.-L. Imbach
Pages: 469-470
Published online: 05 Dec 2006
AbstractforUnexpected Transposition of a Deoxyguanosine Derivative | References | PDF (87.3 KB)
  • 15 Views
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Article
α-DNA. Synthesis, Characterization and Base-Pairing Properties of Unnatural α-Oligodeoxyribonucleotides
P. Morvan, B. Rayner, J.-L. Imbach, D.-K. Chang & J. W. Lown
Pages: 471-472
Published online: 05 Dec 2006
Abstractforα-DNA. Synthesis, Characterization and Base-Pairing Properties of Unnatural α-Oligodeoxyribonucleotides | References | PDF (83 KB)
  • 14 Views
  • 7 CrossRef citations
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Article
Amide Protection in Oligodeoxynucleotide Synthesis
Joachim W. Engels & Matthias Mag
Pages: 473-475
Published online: 05 Dec 2006
AbstractforAmide Protection in Oligodeoxynucleotide Synthesis | References | PDF (105.5 KB)
  • 22 Views
  • 6 CrossRef citations
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Article
Preparation of 15N Labeled Nucleosides and Large Scale Synthesis of Labeled Oligonucleotides with a New Type DNA-Synthesizer
B. Fera, B. Singrün, G. Kupferschmitt, J. Schmidt, F. Buck & H. Ruterjans
Pages: 477-481
Published online: 05 Dec 2006
AbstractforPreparation of 15N Labeled Nucleosides and Large Scale Synthesis of Labeled Oligonucleotides with a New Type DNA-Synthesizer | References | PDF (179.9 KB)
  • 25 Views
  • 7 CrossRef citations
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Article
Oligonucleotide Analogues with Dialkyl Silyl Internucleoside Linkages
Hartmut Seliger & Georg Feger
Pages: 483-484
Published online: 05 Dec 2006
AbstractforOligonucleotide Analogues with Dialkyl Silyl Internucleoside Linkages | References | PDF (104.7 KB)
  • 17 Views
  • 8 CrossRef citations
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Article
Automated Preparation of DNA-RNA Hybrids and their Joining with RNA Ligase; An Approach to Single-Strand Gene Synthesis
D. Zeh & H. Seliger
Pages: 485-488
Published online: 05 Dec 2006
AbstractforAutomated Preparation of DNA-RNA Hybrids and their Joining with RNA Ligase; An Approach to Single-Strand Gene Synthesis | References | PDF (121.8 KB)
  • 21 Views
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Article
Use of Long Oligonucleotides in Gene Synthesis: Chemical Synthesis and Cloning of a Gene for Salmon Calcitonin
F. Hein, H. W. Jansen & E. Uhlmann
Pages: 489-490
Published online: 05 Dec 2006
AbstractforUse of Long Oligonucleotides in Gene Synthesis: Chemical Synthesis and Cloning of a Gene for Salmon Calcitonin | PDF (101.2 KB)
  • 11 Views
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Article
The 9-Fluorenylmethyloxycarbonyl (Fmoc) Group as a 5′-O Base Labile Protecting Group in Solid Supported Oligonucleotide Synthesis
Yunxi Ma & Etienne Sonveaux
Pages: 491-493
Published online: 05 Dec 2006
AbstractforThe 9-Fluorenylmethyloxycarbonyl (Fmoc) Group as a 5′-O Base Labile Protecting Group in Solid Supported Oligonucleotide Synthesis | References | PDF (105.9 KB)
  • 72 Views
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Article
2′-Deoxycoformycin: Biosynthesis and Enzymatic Conversion of 8-Keto-Deoxycoformycin to 2′-Deoxycoformycin by Streptomyces Antibioticus
Jeffery C. Hanvey, Elma Smal, Robert J. Suhadolnik & David C. Baker
Pages: 495-496
Published online: 05 Dec 2006
Abstractfor2′-Deoxycoformycin: Biosynthesis and Enzymatic Conversion of 8-Keto-Deoxycoformycin to 2′-Deoxycoformycin by Streptomyces Antibioticus | References | PDF (85.1 KB)
  • 21 Views
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Article
Cordycepin Analogs of 2–5 a as Activators of RNase L: Study of the Structural Requirements for RNase L Activation
Katalin Kariko, Nancy L. Reichenbach, Robert J. Suhadolnik, Ramamurthy Charubala & Wolfgang Pfleiderer
Pages: 497-500
Published online: 05 Dec 2006
AbstractforCordycepin Analogs of 2–5 a as Activators of RNase L: Study of the Structural Requirements for RNase L Activation | References | PDF (189.6 KB)
  • 21 Views
  • 1 CrossRef citations
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Article
Base Labile Protecting Groups for Hydroxyl Functions in Ribonucleosides and Deoxyribonucleosides
H. Schirmeister & W. Pfleiderer
Pages: 501-503
Published online: 05 Dec 2006
AbstractforBase Labile Protecting Groups for Hydroxyl Functions in Ribonucleosides and Deoxyribonucleosides | References | PDF (103.4 KB)
  • 50 Views
  • 3 CrossRef citations
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Article
Synthesis of 2′-O-p-Nitrophenylethylsulfonyl-Ribonucleosides
M. Pfister & W. Pfleiderer
Pages: 505-507
Published online: 05 Dec 2006
AbstractforSynthesis of 2′-O-p-Nitrophenylethylsulfonyl-Ribonucleosides | References | PDF (103 KB)
  • 19 Views
  • 5 CrossRef citations
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Article
Synthesis of Modified Thymidine Dimers
S. Farkas & W. Pfleiderer
Pages: 509-511
Published online: 05 Dec 2006
AbstractforSynthesis of Modified Thymidine Dimers | References | PDF (75.4 KB)
  • 15 Views
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Article
Synthesis of P-Thioadenylyl (2′-5′) Adenosine and P-Thioadenylyl (2′-5′)-P-Thioadenylyl-(2′-5′)-Adenosine
R. Charubala & W. Pfleiderer
Pages: 513-516
Published online: 05 Dec 2006
AbstractforSynthesis of P-Thioadenylyl (2′-5′) Adenosine and P-Thioadenylyl (2′-5′)-P-Thioadenylyl-(2′-5′)-Adenosine | References | PDF (134.6 KB)
  • 12 Views
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Article
2′-OH Protection by the p-Nitrophenylethylsulfonyl (NPES) Group in Oligoribonucleotide Synthesis
R. Charubala & W. Pfleiderer
Pages: 517-520
Published online: 05 Dec 2006
Abstractfor2′-OH Protection by the p-Nitrophenylethylsulfonyl (NPES) Group in Oligoribonucleotide Synthesis | References | PDF (143.1 KB)
  • 13 Views
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Article
2′5′-Phosphodiesterase Activity Studies with Xyloadenosine Analogs of 2–5A Cores
P. P. Torrence, D. Alster, S. Huss, G. Gosaelin & J.-L. Imbach
Pages: 521-522
Published online: 05 Dec 2006
Abstractfor2′5′-Phosphodiesterase Activity Studies with Xyloadenosine Analogs of 2–5A Cores | References | PDF (77.8 KB)
  • 12 Views
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Article
Only One 3′-Hydroxyl Group Of ppp 5′A 2′p 5′A 2′p 5′A(2–5A) is Required for Activation of the Mouse 2–5A-Dependent Endonuclease
P. F. Torrence, D. Alster, R. Charubala, W. Pfleiderer & D. Brozda
Pages: 523-524
Published online: 05 Dec 2006
AbstractforOnly One 3′-Hydroxyl Group Of ppp 5′A 2′p 5′A 2′p 5′A(2–5A) is Required for Activation of the Mouse 2–5A-Dependent Endonuclease | PDF (106.9 KB)
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  • 1 CrossRef citations
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Article
2′,5′-Phosphodiesterase Activity Depends Upon the Presence of a 3-Hydroxyl Moiety in the Penultimate Position of the Oligonucleotide Substrate
David Alster, Danuta Brozda, Yukio Kitade, Alice Wong, Ramamurthy Charubala, Wolfgang Pfleiderer & Paul Torrence
Pages: 525-526
Published online: 05 Dec 2006
Abstractfor2′,5′-Phosphodiesterase Activity Depends Upon the Presence of a 3-Hydroxyl Moiety in the Penultimate Position of the Oligonucleotide Substrate | PDF (85.2 KB)
  • 10 Views
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Article
Synthesis of 2′-5′ Adenylate Trimers Containing 3′-Modified β-D-Xylofuranosyl-Adenine Derivatives at the 2′-End
K. Ruf, P. Herdewijn & W. Pfleiderer
Pages: 527-528
Published online: 05 Dec 2006
AbstractforSynthesis of 2′-5′ Adenylate Trimers Containing 3′-Modified β-D-Xylofuranosyl-Adenine Derivatives at the 2′-End | References | PDF (78.6 KB)
  • 11 Views
  • 1 CrossRef citations
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Article
Synthesis of 06-Alkylated Guanosine and Deoxyguanosinephosphoramidites
B. S. Schulz & W. Pfleiderer
Pages: 529-531
Published online: 05 Dec 2006
AbstractforSynthesis of 06-Alkylated Guanosine and Deoxyguanosinephosphoramidites | References | PDF (84.5 KB)
  • 24 Views
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Article
5-Substituted 2-(Pyrimidin-2-yl)-Ethanols as New Phosphate Protecting Groups
T. Reiner & W. Pfleiderer
Pages: 533-535
Published online: 05 Dec 2006
Abstractfor5-Substituted 2-(Pyrimidin-2-yl)-Ethanols as New Phosphate Protecting Groups | References | PDF (86.1 KB)
  • 15 Views
  • 1 CrossRef citations
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Article
Synthesis of Terminal Nucleoside Phosphates and Thiophosphates via Phosphoramidite Chemistry
M. W. Schwarz & W. Pfleiderer
Pages: 537-539
Published online: 05 Dec 2006
AbstractforSynthesis of Terminal Nucleoside Phosphates and Thiophosphates via Phosphoramidite Chemistry | References | PDF (102.9 KB)
  • 27 Views
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Article
Synthesis and Hybridization Characteristics of Oligodeoxynucleotide-Alkaline Phosphatase Conjugates
Jerry L. Ruth & Edward Jablonski
Pages: 541-542
Published online: 05 Dec 2006
AbstractforSynthesis and Hybridization Characteristics of Oligodeoxynucleotide-Alkaline Phosphatase Conjugates | References | PDF (97.3 KB)
  • 14 Views
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Editorials

Editorial
Editorial board page for “Nucleosides & Nucleotides”, Volume 6, Number 1-2
Page: a
Published online: 05 Dec 2006
AbstractforEditorial board page for “Nucleosides & Nucleotides”, Volume 6, Number 1-2 | PDF (57.7 KB)
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