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Nucleosides and Nucleotides Volume 6, 1987 - Issue 1-2
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COMMUNICATIONS

DNA Base Pair Binding Specificity of CC-1065

Nicole Y. Thériault Biopolymer Chemistry, The Upjohn Company, Kalamazoo, Ml, 49001, U.S.A.
,
William C. Krueger Physical and Analytical Chemistry, The Upjohn Company, Kalamazoo, Ml, 49001, U.S.A.
&
Mark D. Prairie Physical and Analytical Chemistry, The Upjohn Company, Kalamazoo, Ml, 49001, U.S.A.
Pages 327-330 | Published online: 05 Dec 2006
 
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Abstract

Oligomer duplexes were prepared by a solid-phase phosphoramidite triester coupling approach in order to study the DNA base pair binding specificity of the antitumor antibiotic CC-1065 by CD spectroscopy.

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