New Approach to the Synthesis of 2′(3′)-O-Aminoacyloligoribonucleotides Related to the 3′-Terminus of Aminoacyl Transfer Ribonucleic Acid

Abstract

A new methodology for the synthesis of 2′(3′)-0-aminoacyl oligonucleotides based on an unique combination of protecting groups is described. The blocking scheme allows a simple two step deblocking procedure, which provides easy access to the target compounds.