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Amide Protection in Oligodeoxynucleotide Synthesis

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Pages 473-475 | Published online: 05 Dec 2006
 

Abstract

Several O6 -protected deoxyguanosine- as well as O4 -protected thymidine-phosphoramidites were prepared according to the Mitsunobu reaction and Michael addition and were tested in a solid-phase automated DNA synthesizer.

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