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Nucleosides and Nucleotides Volume 6, 1987 - Issue 1-2
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Synthesis of Modified Thymidine Dimers

S. Farkas Fakultät für Chemie, Universität Konstanz, D-7750, Konstanz
&
W. Pfleiderer Fakultät für Chemie, Universität Konstanz, D-7750, Konstanz
Pages 509-511 | Published online: 05 Dec 2006
 
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Abstract

A1kylating agents are mutagenic and carcinogenic substances due to reaction with the pyrimidine and purine bases of the various nucleic acids. The thymine base can be alkylated at N3-, 02 - or 04-position. Their behaviour during transcription and replication is unknown (1).

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