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Nucleosides and Nucleotides Volume 16, 1997 - Issue 7-9
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II. MEDICINAL CHEMISTRY OF NUCLEOSIDES/NUCLEOTIDES

Dinucleotides Incorporating Isomeric Nucleosides: Synthesis, Structural and Stereochemical Characterization, and Enzymology

Tamera S. Jahnke Department of Chemistry, The University of Iowa, Iowa City, IA, 52242, U.S.A.
,
Qi Chao Department of Chemistry, The University of Iowa, Iowa City, IA, 52242, U.S.A.
&
Vasu Nair Department of Chemistry, The University of Iowa, Iowa City, IA, 52242, U.S.A.
Pages 1087-1090 | Published online: 16 Aug 2006
 
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Abstract

The synthesis, stability toward nucleases, and conformational properties of 3′→5′ and 5′→5′ dinucleotides bearing an isomeric nucleoside component is described.

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