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Nucleosides and Nucleotides
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Volume 16, Issue 7-9
Synthesis of New 1,2,3-Triazole Acyclonu ....

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Nucleosides and Nucleotides Volume 16, 1997 - Issue 7-9

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II. MEDICINAL CHEMISTRY OF NUCLEOSIDES/NUCLEOTIDES

Synthesis of New 1,2,3-Triazole Acyclonucleoside Analogues of ACV and HBG

H. B. Lazrek Laboratoire de Chimie Bio-Organique, Faculté des Sciences Semlalia, BP S15, Marrakech, Maroc.

M. Taourirte Laboratoire de Chimie Bio-Organique, Faculté des Sciences Semlalia, BP S15, Marrakech, Maroc.

T. Oulih Laboratoire de Chimie Bio-Organique, Faculté des Sciences Semlalia, BP S15, Marrakech, Maroc.

M. Lebtoumi Laboratoire de Chimie Bio-Organique, Faculté des Sciences Semlalia, BP S15, Marrakech, Maroc.

J. L. Barascut Laboratoire de Chimie Bio-Organique, Université des Sciences et Techniques Montpellier II, France

J. L. Imbach Laboratoire de Chimie Bio-Organique, Université des Sciences et Techniques Montpellier II, France

Pages 1115-1118 | Published online: 16 Aug 2006

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https://doi.org/10.1080/07328319708006145

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Abstract

1,3-dipolar cycloaddition of. N-9/N-1-propargylpurine/pyrimidine to the corresponding azido-compounds 9–10 produces acyclonucleoside analogues 13a-h, 14a-h in which the 4-methyl-1,2,3-triazole is used as spacer arm.

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