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Nucleosides and Nucleotides Volume 16, 1997 - Issue 7-9
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V. NOVEL NUCLEOSIDES AND OLIGOMERS

Novel Bicyclic Nucleoside Analogues Related to Natural Griseolic Acids

Lea Pickering Department of Chemistry, The University of Iowa, Iowa City, IA, 52242, U.S.A.
&
Vasu Nair Department of Chemistry, The University of Iowa, Iowa City, IA, 52242, U.S.A.
Pages 1435-1438 | Published online: 16 Aug 2006
 
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Abstract

Methodologies for the synthesis of novel isomeric nucleosides related to the natural, biologically-active griseolic acids are described. The carbohydrate precursor for the synthesis, 1,4:3,6-dianhydro-d-glucitol, can be prepared easily from d-glucitol.

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