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Nucleosides and Nucleotides Volume 16, 1997 - Issue 7-9
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VI. CHEMICAL DEVELOPMENT AND ANALYTICAL CHEMISTRY

Solution Phase Synthesis of an Oligodeoxyribonucleotide Phosphorothioate for Therapeutic Applications

Z. S. Cheruvallath Isis Pharmaceuticals, 2292 Faraday Avenue, Carlsbad, CA, 92008
,
A. H. Krotz Isis Pharmaceuticals, 2292 Faraday Avenue, Carlsbad, CA, 92008
,
D. L. Cole Isis Pharmaceuticals, 2292 Faraday Avenue, Carlsbad, CA, 92008
&
V. T. Ravikumar Isis Pharmaceuticals, 2292 Faraday Avenue, Carlsbad, CA, 92008
Pages 1625-1628 | Published online: 16 Aug 2006
 
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Abstract

Solution phase synthesis of an oligodeoxyribonucleotide phosphorothioate Octamer (5′-TTGGGGTT) using phosphorothioate triester method is reported.

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