A New Model for the Comparison of the Efficiency and Selectivity of Photoreactive Groups Towards the Nucleic Acid and Protein Functional Groups

Dmitri G. Knorre Institute of Bioorganic Chemistry, Lavrentyev St. 8, Novosibirsk, 630090, Russia

Tatyana S. Godovikova Institute of Bioorganic Chemistry, Lavrentyev St. 8, Novosibirsk, 630090, Russia

Vera D. Knorre Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow

Vladimir V. Koval Institute of Bioorganic Chemistry, Lavrentyev St. 8, Novosibirsk, 630090, Russia

Abstract

A new model for the comparison of the efficiency and selectivity of photoreactive groups towards the nucleic acid and protein functional groups is described. It was shown that reagents carrying p-azidoaniline residue are the most efficient and selective for the modiication of the side radicals of amino acids.

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A New Model for the Comparison of the Efficiency and Selectivity of Photoreactive Groups Towards the Nucleic Acid and Protein Functional Groups

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A New Model for the Comparison of the Efficiency and Selectivity of Photoreactive Groups Towards the Nucleic Acid and Protein Functional Groups

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