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Pediatric Hematology and Oncology Volume 24, 2007 - Issue 6
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Brief Report

GOT PURE BLOOD IN FETAL RATS?

C. Mao Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
J. Guan Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China; Department of Microbiology, Bengbu Medical College, Bengbu, Anhui, China
,
X. Yuan Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
Y. Miao Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
H. Zhu Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
L. Chen Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
J. Lv Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
F. Xu Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
Y. Liu Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
P. Hui Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
,
Y. Zhu Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China
&
Z. Xu Perinatal Biology Center, Soochow University School of Medicine, Suzhou, China; Center for Perinatal Biology, Loma Linda University, California, USA
 show all
Pages 457-460 | Received 20 Feb 2007, Accepted 24 Apr 2007, Published online: 09 Jul 2009
 
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Abstract

Have you felt frustration when fetal blood is needed for your studies in rats, or have you been concerned about fetal rat “blood” collected from decapitation? The traditional approach has been to collect fetal blood from decapitation of fetuses. The new method of collecting fetal blood is from the fetal heart, and makes it possible to obtain pure fetal blood at near-term in rodents for fetal studies. This study also demonstrated a significant difference of fetal blood oxygen levels between the traditional and new methods of blood collection.

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