The pulsatile 3D-Hemodynamics in a doubly afflicted human descending abdominal artery with iliac branching

Abstract

The study of patient-specific human arterial flow dynamics is well known to face challenges like a) apt geometric modelling, b) bifurcation zone meshing, and c) capturing the hemodynamic prone to variations with multiple disease complications. Due to aneurysms and stenosis in the same arterial network, the blood flow dynamics get affected, which needs to be explored. This study develops a new protocol for accurate geometric modelling, bifurcation zone meshing and numerically investigates the arterial network with abdominal aortic aneurysms (AAA) and right internal iliac stenosis (RIIAS). A realistic arterial model is reconstructed from the computed tomography (CT) data of a human subject. To understand the combined effect of the aneurysm and aortoiliac occlusive diseases in a patient, an arterial network with AAA, RIIAS, multiple branches tapering, and curvature has been considered. Clinically significant pulsatile blood flow simulations have been carried out to trace the alteration in the flow dynamics with multiple pathological complications under consideration. The transient blood flow dynamics are investigated via wall shear stress, wall pressure, velocity contour, streamlines, vorticity, and swirling strength. During the systolic deceleration phase, the rhythmic nested rapid secondary oscillatory WSS, adverse pressure gradients, high WSS, and high WP bands are noticed. Also, the above studies will help researchers, clinicians, and doctors understand the influence of morphological changes on hemodynamics in cardiovascular studies.

Keywords:

• Abdominal artery
• aneurysm
• iliac-stenosis
• WSS
• finite volume method
• CFD

Acknowledgements

The authors would like to acknowledge Department of Radiology, Institute of Medical Science, BHU, and Varanasi, India, for ethical clearance and data support and acknowledge the School of Biomedical Engineering, Indian Institute of Technology BHU, Varanasi for heavy workstation facilities support.

Disclosure statement

There is no conflict of interest in this work.

Additional information

Funding

The authors would like to acknowledge ICMR, Govt of India, for funding and support, file Project File No: GIA/2019/000607/PRCGIA IRIS cell, ICMR, ID. No. 2020-9527.