Abstract
A facile, eco-friendly and effective ultrasonic strategy to synthesize S-arylated-pyridopyrimidines is described starting from 4-thiol or 4-halogenopyridopyrimidines through a reaction involving a green procedure under ultrasonic irradiation and in presence of water as green solvent. The resulted derivatives were assessed for the antibacterial activity against different bacteria strains.
Graphical Abstract
![](/cms/asset/c0117bc8-0720-4790-bb1f-97b65031f062/gpol_a_1984953_uf0001_c.jpg)
Acknowledgment
Dr. Abuzer Ali is thankful to Taif University Researchers Supporting Project Number (TURSP-2020/124), Taif University, Taif, Saudi Arabia.
Disclosure statement
No potential conflict of interest was reported by the authors.