An Interesting and Highly Efficient Route to 2-(Arylethynyl)Selanyl-Azoles: Fe₃O₄-Serine-CuI Nanocomposite Catalyzed Three-Component Coupling Reaction of Azoles, Se Powder, and Alkynes

Abstract

2-(arylethynyl)selanyl-azoles are important and vital compounds that both azoles and aryl ethynyl selenides presented in their structure. In this article, we have constructed copper (I) iodide supported on the surface of magnetic Fe₃O₄ nanoparticles functionalized with Serine [Fe₃O₄-Serine-CuI] and evaluated its catalytic behavior in the preparation of 2-(arylethynyl)selanyl-azoles though one-pot three-component coupling reaction of azoles, Se powder and alkynes under ecofriendly conditions. The structure of Fe₃O₄-Serine-CuI nanocatalyst is well analyzed by several spectroscopic techniques like: FT-IR, SEM, EDX, TEM, MAP, XRD, TGA, VSM, ICP-OES techniques. High reusability and well characterization of Fe₃O₄-Serine-CuI nanocatalyst, high purity and yields of products, ecofriendly conditions, and simple operation are several considerable advantages this catalytic system.

Keywords:

• Fe₃O₄-Serine-CuI nanocatalyst
• 2-(arylethynyl)selanyl-azoles
• ecofriendly conditions
• high reusability
• three-component reactions

Disclosure statement

No potential conflict of interest was reported by the author(s).