Carbon Dots in the Detection of Pathogenic Bacteria and Viruses

Abstract

Bacterial and viruses pathogens are a significant hazard to human safety and health. In the imaging and detection of pathogenic microorganisms, the application of fluorescent nanoparticles is very useful. Carbon dots and quantum dots are preferred in this regard as labels, amplifiers, and/or electrode modifiers because of their outstanding features. However, precise diagnostics to identify numerous harmful bacteria simultaneously still face considerable hurdles, yet it is an inevitable issue. With the growing development of biosensors, nanoproduct-based bio-sensing has recently become one of the most promising methods for accurately identifying and quantifying various pathogens at low cost, high sensitivity, and selectivity, with time savings. The most recent applications of carbon dots in optical and electrochemical-based sensors are discussed in this review, along with some examples of pathogen sensors.

Highlights

• Simultaneous and early detection of pathogens is a critical issue in the management of readily spread to prevent epidemics.

• Carbon dots-based biosensors are more preferred in detection of pathogens due to high selectivity and sensitivity, as well as quick and cheap point-of-care platform.

• Summary of recent advances in the design of optical and electrochemical biosensors for the detection of pathogens.

Graphical Abstract

Keywords:

• Pathogen
• carbon dots
• graphene quantum dots
• virus detection
• bacteria detection
• optical sensor
• electrochemical sensor