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Phosphorus, Sulfur, and Silicon and the Related Elements Volume 197, 2022 - Issue 5-6: ICPC-23: 23rd International Conference on Phosphorus Chemistry; Guest Editors:Professor Jozef Drabowicz; Professor Piotr Kiełbasiński and Professor Tomasz Cierpiał
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Short Communication

The synthesis of hydroxymethylenebisphosphonic- (dronic-) and acyl-ethoxycarbonyl-methylphosphonate derivatives

György KeglevichDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, HungaryCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5366-472XView further author information
ORCID Icon,
Zsuzsanna SzalaiDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, HungaryView further author information
,
Kinga V. GulyásDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, HungaryView further author information
,
Róbert ZahárDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, HungaryView further author information
,
Alajos GrünDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, HungaryORCID Iconhttps://orcid.org/0000-0001-8710-7326View further author information
ORCID Icon &
Csilla Sepsey FürDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, HungaryORCID Iconhttps://orcid.org/0000-0003-3356-1616View further author information
ORCID Icon
Pages 520-522 | Received 24 Sep 2021, Accepted 23 Oct 2021, Published online: 08 Dec 2021
 
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Abstract

Recent results on the synthesis of substituted hydroxymethylenebisphosphonic acids (A and B), as well as acylated ethoxycarbonyl-methylphosphonate derivatives (C and D) are summarized. In the first part, solvent mixtures were applied in the preparation of known dronic acids, while in the second series of experiments, new acyl species were synthesized.

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Additional information

Funding

This project was supported by the National Research, Development and Innovation Office (K134318).

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